525 search results for “genome organization” in the Public website
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Spatiotemporal Organization of Organelles through Membrane Contact Sites
PhD defence
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Flu stops when you block the enzyme that cleaves off virus particles
A flu virus could cause a pandemic. And then we would be poorly armed because flu viruses are starting to become resistant to flu medications like Tamiflu. Chemist Merijn Vriends successfully worked on an improved version of such medications. He will be awarded his doctorate on September 12th.
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The hunt for frozen organic molecules in space
PhD defence
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launch: Kseniya Oksamytna - Advocacy and Change in International Organizations
Lecture
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Ancient DNA provides new insights into the early peopling of the Caribbean
According to a new study by an international team of researchers from the Caribbean, Europe and North America, the Caribbean was settled by several successive population dispersals that originated on the American mainland.
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Political scientist Juan Masullo awarded Elise Mathilde Fund/LUF grant for research on public attitudes towards the mafia
Juan Masullo (Leiden University Institute of Political Science) receives a grant from the Elise Mathilde Fund/Leiden University Fund to conduct his research project ‘Forging an Anti-Mafia Culture: Observational and Experimental Evidence from Italy’. Masullo aims to find out what ordinary Italians think…
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ERC Starting Grants for five young researchers from Leiden University
The ERC Council has awarded Starting Grants to five promising Leiden researchers. With an impressive three laureates, the Faculty of Social and Behavioural Sciences has done particularly well. The fourth grant goes to the LUMC and the fifth to the Faculty of Governance and Global Affairs.
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Medicine development is hunting magic bullets
Medicines are becoming increasingly precise and innovative, but at the same time increasingly expensive. With their innovations, it is up to universities to increase competition, thus causing prices to drop. This is what newly appointed Professor of Biomolecular Analysis Hubertus Irth argues. His inaugural…
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Building bridges between science and business
The scientific world is under increasing pressure from all directions: the money that society invests has to show clear returns. ‘The best thing we can do is to go along with this development,' says Ivo de Nooijer, Director of Luris, Leiden University's valorisation institute.
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Youthful DNA in old age
The DNA of young people is regulated to express the right genes at the right time. With the passing of years, the regulation of the DNA gradually gets disrupted, which is an important cause of ageing. A study of over 3,000 people shows that this is not true for everyone: there are people whose DNA appears…
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“Kees Bakker" award for Thijmen Breeschoten
Leiden Biology student Thijmen Breeschoten received the annual award for being the best BSc-student in 2013 from the “Stichting Professor Dr. K. Bakker-fonds”.
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NWO Projectruimte Grant for DNA Flexibility Research
Theoretical physicist Helmut Schiessel receives an NWO Projectruimte grant of 390,000 euro. He will use this budget to hire a postdoc and a PhD student to continue his research on flexibility of double stranded DNA.
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Delegation of Holland Rijnland visits the Institute of Biology
On Thursday the 24th of November, Tseard Hoekstra and Jeroen Ververs (members of the delegation Holland Rijnland), Geert de Snoo (Dean Faculty of Science), Martina Vijver (CML), Herman Spaink (Scientific Director IBL) and Klaas Vrieling (IBL) explored possibilities for collaborations between companies…
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Awards and Grants 2020
An overview of awards and prizes granted to our staff and students in 2020, as well as special appointments at Leiden University and other institutions.
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Dynamics and practices of internationalisation in model organism science - a South American perspective
Seminar
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Workers of Istanbul Unite! A Socialist Workers' Organization in the Late Ottoman Capital, 1909-1922
Lecture, LUCIS What's New?! Series
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Correcting each other’s mistakes - why cells stuck together in early evolution
The transition from single cells to multicellular organisms was a key step in evolution. Researchers from Leiden and Amsterdam developed a mathematical model that explains how this transition may have come about. They suspect cooperating cells may correct each other’s mistakes. Publication in eLife…
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IBL symposium “Integrative Biology towards Healthy Communities”
On Monday the 8th of December, the annual symposium of the IBL will be organized at the main building of the LUMC Leiden. This year’s theme is “Integrative Biology towards Healthy Communities”.
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Supramolecular and Biomaterials Chemistry
Alexander Kros studies supramolecular systems in a biological environment. The unifying theme between the projects in my lab is specific molecular recognition, i.e. the intermolecular interaction between complementary molecules with high affinity and selectivity. Studying, imitating and dissecting processes…
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Cancer pathogenesis and therapy
With cancer, a person’s body cells grow uncontrollably. Putting together a detailed picture of how this comes about makes it possible to develop efficient therapies. Researchers at the Leiden University Medical Centre (LUMC) and Leiden University are working together to gain a better understanding…
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Publications
Relevant publications of the CIGR participants.
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Overview
The Division of Systems Pharmacology and Pharmacy (SPP) aims to develop precision medicine approaches to characterise and predict variation in treatment response and enhance translational drug development strategies.
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Sea sponges may seem like simple creatures, but…
One of them turned out to be two thousand years old. And older giant barrel sponges appear to have a faster rate of cell division, unlike us. They produce antibiotics and much, much more. Lina Bayona Maldonado studied how the differences in such factors as age or oceanic depth affect the production…
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resistance: defense against enteropathogens and multi-drug resistant organisms
PhD defence
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supramolecular chemistry approach for potentiating live attenuated whole-organism vaccines
PhD defence
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investigations into the role of ceramide subclass composition on lipid organization and skin barrier
PhD defence
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determinants of effective eHealth: high-quality applications and optimal organization
PhD defence
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challenge of quality assessment and regional perfusion to increase donor organ utilisation
PhD defence
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Gene Networks-based Mechanistic Assessment of Drug-induced Organ Toxicity
PhD defence
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The bite that heals: New antibiotics with help from venomous animals
Prof. Gilles van Wezel and Prof. Mike Richardson of the Institute of Biology Leiden received €1.4 million to find new antibiotics.
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Reading through proteins with graphene: NWO Vidi grant awarded to Dr. Grégory Schneider
While there are numerous and extremely advanced methods to sequence the genome, only a few methods exist to sequence the proteome. The Vidi project of Grégory Schneider promises to shed light on the most difficult paradigm of proteomics: achieving an error-free determination of the sequence of single…
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New collaboration aims to predict cancer survival
Predicting cancer survival with machine learning, that is the aim of a new collaboration between the Mathematical Institute, the European Organisation for Research and Treatment of Cancer (EORTC) in Brussels and Leiden University Medical Center. The focus of this project is to characterise the model…
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New STW-grant to redirect the plant micro biome: “Back to the Roots”
Professors Jos Raaijmakers (NIOO) and Gilles Van Wezel (IBL) received an STW Perspectief- grant of €3 million from the Dutch Technology Foundation and several supporting companies.
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Vici grants for three Leiden researchers
Three Leiden researchers have been awarded a prestigious Vici grant, the Dutch Research Council (NWO) announced on Tuesday. Two of the researchers work at Leiden University and the third at the Leiden University Medical Center (LUMC).
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Andrew Littlejohn awarded Hunt Postdoctoral Fellowship
Dr. Andrew Littlejohn has been awarded a Hunt Postdoctoral Fellowship by the Wenner-Gren Foundation for Anthropological Research. The fellowship provides funds for early-career scholars to write and publish significant monographs that will impact the development of anthropology.
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Big data cannot do without statistics
Data science and statistics are closely linked, says Spinoza laureate and Stochastics professor Aad van der Vaart. We talk with him about the big data hype, genome research and collaboration with other disciplines. ‘Statistics helps wherever data is not perfect.’
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Zebrafish models for disease and environmental stress
We use zebrafish as a model organism to study human development and disease as well as animal welfare and environmental impact.
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Ten years of Life Science and Technology
On September 9th 2009, the study Life Science and Technology (LS&T) celebrates its 10th anniversary. In 1999, a group of enthusiastic pioneers within the Technical University Delft (TUD) and Leiden University (LU) founded a novel study based on the biotechnological expertise of research institutes within…
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LUMC offers free online course on transplantation
The LUMC is the first medical institution in the world to offer a Massive Open Online Course (MOOC) on clinical kidney and pancreas transplantation.
- to be an Academic in a World on Fire: A Hands-On Workshop co-organized with LUGO
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DNA folded in compliant helix
In an Advance Online Publication biophysicist John van Noort and others show using magnetic tweezers that DNA is folded in compliant helices of chromatin. This allows enzymes access to the DNA needed for gene expression. Van Noort's research group made the discovery in close partnership with researchers…
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Artificial intelligence helps in the search for new antibiotics
With the search for new antibiotics becoming increasingly urgent, artificial intelligence offers valuable help. Smart software developed by Leiden PhD candidate Alexander Kloosterman searched genomes of bacteria and found clusters of DNA that code for proteins that have an antibiotic effect. ‘This new…
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Producing new plants without sowing
Producing offspring of a crop without sowing and that is even bigger than the parent plant. According to Leiden researchers this can be achieved by overstimulating a single gene that rejuvenates cells, including bringing them back to the embryonic phase.
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AI, Healthcare, and the Law Panel at CPDP 2020
On 24 January 2020, eLaw attended the Annual Conference on Privacy and Data Protection (CPDP) in Brussels, Belgium. The overarching theme of the 13th edition was
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IBL-research interview: Daniel Rozen
Daniel Rozen (45), at the IBL since September 2012, uses bacteria in laboratory tests on experimental evolution to study the ecology and genetics of adaptation. His research has applied importance, as it reveals how bacteria may be induced to produce new antibiotics. Last January, Rozen received the…
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European collaboration shines a light on enzyme discovery for industry
A European consortium has provided a disruptive technological breakthrough to allow the discovery and characterization of novel enzymes for industrial biotechnology. The technology will open the way to more efficient industrial processes such as in the biofuel, animal feed and paper and pulp industr…
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Feodor-Lynen research fellowship for Bela Bode
Dr Bela Bode receives a Feodor Lynen research fellowship for postdoctoral researchers by the Alexander von Humboldt-Foundation for development of new methods for signal enhancement in solid state NMR. He aims to create a specific analytical tool for surface studies and research on membranes and membrane…
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Preventing or curing diseases with X-omics
In April, the X-omics initiative was granted 17 million euros from the Dutch Organization for Scientific Research. The subsidy is part of the National Roadmap for large-scale scientific infrastructure, intended to build or renew large-scale research facilities. What new insights will this investment…
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‘Using real-world data to enhance our healthcare system’
On 16 May 2022, Professor Michel Wouters from the Department of Biomedical Data Sciences at the Leiden University Medical Centre (LUMC), will deliver his inaugural lecture titled ‘Quality of Cancer Care: why the real world matters’. Wouters will use the opportunity to describe how quality registries…
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Science Groot funding for Leiden scientists
Leiden scientists are the main applicants for five projects that have been awarded a Science Groot grant of up to 3 million euros in the Science Domain. In addition, several Leiden scientists are involved in other projects that have been awarded funding.