2,233 search results for “drug safety” in the Public website
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Madouc Bergers made her own enzyme inhibitors for her bachelor’s thesis
For her bachelor’s thesis, Molecular Science and Technology student Madouc Bergers synthesized her own molecule that can inhibit the breakdown of sugars. Although most students do not even manage to make one building block, Madouc made three. Partly because of this, she has been nominated for the Science…
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Tom van der Wel
Science
t.van.der.wel@lic.leidenuniv.nl | +31 71 527 3527
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Serkan Aslan
Science
s.aslan@lacdr.leidenuniv.nl | +31 71 527 5919
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Erik Danen
Science
e.danen@lacdr.leidenuniv.nl | +31 71 527 4486
- Coordinators
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Quantitative pharmacology approaches to inform treatment strategies against tuberculosis
Tuberculosis (TB) is associated with 1.5 million deaths annually. There is a need exists to optimize both current as well as novel antibiotic combination treatment strategies to improve the effectiveness and safety of treatments against TB.
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Programme structure
The strengths of this master’s specialisation are its research-orientated approach, combined with training in safety and quality control in the production of medicinal products in the biotechnology and pharmaceutical industry.
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Predicting dementia
In the future, physicians may be able to identify dementia much earlier than they can today because a computer algorithm will be able to predict from brain scans how our memory is going to develop.
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Lifestyle and nutrition to combat diseases (of affluence)
We know this, but we don’t act on it: eat healthily, move more, address our stress levels and sleep well. Internist and Professor of Diabetology Hanno Pijl is fascinated by the effect that a healthy lifestyle can have on health. He researches how this lifestyle is achievable and satisfying, for patients…
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Animal Sciences
We perform multidisciplinary research at molecular, cellular, and organismal levels of animal biology to increase fundamental understanding of health and disease.
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Glucocorticoid modulation of the immune response
Unraveling the immune-suppressive actions of drugs like prednisone.
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ZF-CANCER - Developing high-throughput bioassays for human cancers in zebrafish
How can zebrafish research help to understand and fight human cancer?
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FAQ research with animals
Antwoord op veelgestelde vragen over onderzoek met proefdieren bij de Universiteit Leiden. FAQ
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Infrastructure
An overview of our infrastructure at the SPP division:
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Exploring the mechanisms of metastatic onset for novel treatment strategies
This thesis represents a comprehensive investigation into the control of cancer stemness and metastatic initiation using a combination of advanced zebrafish xenograft models and in vitro assays.
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Search and rescue: tackling antibiotic resistance with chemistry
With the rise of multi-drug resistant bacterial pathogens, the possibility of a post-antibiotic world is quickly becoming reality.
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Novel chemical tools for target validation in neuroinflammation
In what way can new tools and techniques be used to develop drug candidates for the treatment of neurological disorders?
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Advanced Pre-clinical Evaluation of the Guanidino Lipoglycopeptides: A Novel Family of Glycopeptide Antibiotics with Best-in-Class Potential
Can we make a better vancomycin?
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Development of organ-on-a-chip systems for translational and personalized medicine
We have developed a microfluidic platform for complex 3D organotypic cell cultures (so-called organ-on-a-chip systems) which are suited for integration in 96 or higher well plate format.
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Imaging
The imaging group focuses on bio-imaging, image analysis and visualization.
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Human skin equivalent barrier optimization
The currently available in vitro generated human skin equivalents resemble the human skin in many aspects. However, some essential barrier characteristics do not fully mimic the native barrier. Consequently, the human skin equivalents cannot be used for screening of drugs for skin penetration.
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Bioactive Molecules
Bioactive Molecules is one of the four research themes of the Institute of Biology Leiden.
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Leiden University and LUMC strengthen ties with Janssen pharmaceutical company
Leiden University, the LUMC and Janssen have signed a partnership agreement stating that they will collaborate in different areas, including infectious disease prevention, clinical tests, drug production and e-health. By joining forces, the three partners will be able to provide better, more innovative…
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Graduation Ceremony Interdisciplinary Master Cyber Security
On Thursday 7 February 2019, the graduation ceremony for the executive master programme Cyber Security took place at The Hague Security Delta (HSD). The Cyber Security programme is a collaboration of University Leiden, Delft University of Technology, and The Hague University of Applied Sciences. A total…
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Safety of the Artisan iris-fixated phakic intraocular lens
PhD defence
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Maartje van der Woude
Faculteit Rechtsgeleerdheid
m.a.h.vanderwoude@law.leidenuniv.nl | +31 71 527 7552
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Terrorism and Political Violence
Understanding the evolving landscape of extremism in the 21st century.
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Ensnaring tumours in their own web
Erik Danen is looking at how to inhibit tumours that do not respond well to medicine – and he is making some headway. The Professor of Cancer Drug Target Discovery studies the interaction between tumour cells and their surroundings. Inaugural lecture on Friday 10 May.
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Seven Comenius grants for Leiden lecturers
Eleven lecturers from Leiden University have been awarded Comenius grants that will allow them to work with their teams on an innovation project within their own teaching. They have been awarded three grants of 100,000 euros within the Senior Fellows programme and four grants of 50,000 euros within…
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XAIPRE - Explainable AI For Predictive Maintenance
The project XAIPre (pronounce “Xyper”) aims to develop predictive maintenance system for the maritime industry using sensor technology and artificial intelligence. The project aims at developing Explainable Predictive Maintenance (XPdM) algorithms that do not only provide the engineers with a prediction…
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Scientific integrity
All LIAS members and visitors are kindly requested to familiarize themselves with the information provided below, to the level of detail they feel is appropriate to their situation. This information overlaps in part with the University’s web pages on scientific integrity.
- Facilities and services
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Career prospects
A master's degree in Psychology at Leiden University combines theoretical knowledge with academic and professional skills, making you an attractive candidate for many employers.
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Career prospects
A master's degree in Psychology at Leiden University combines theoretical knowledge with academic and professional skills, making you an attractive candidate for many employers.
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Programme structure
Throughout your 3-year Security Studies programme you explore the effects of events (such as war or natural disaster), understand them via relevant academic perspectives, and actively design strategies and solutions to resulting security challenges.
- Lunch Time Seminar: Applications of Artificial Intelligence in Early Drug Discovery
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Ruling: temporary coffeeshop licences are allowed
Coffeeshop licences may be issued temporarily and reissued after this period has expired. This follows from a ruling by the Administrative Jurisdiction Division of the Council of State in the appeal lodged by the mayor of Roermond municipality against the Court's April 2021 ruling.
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Systems pharmacology-based optimization of postoperative morphine treatment
Previous research has found important inter-individual differences in the pharmacokinetics (PK) of morphine in special populations such as children, the morbidly obese or the critically ill.
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Imaging and Bioinformatics
On the basis of the characteristic aspects of a picture, certain computers can tell us what the picture is showing. They can learn this in the same way that young children are able to learn to recognize images. Further improving these techniques opens the way to a whole range of new applications. Biology…
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Skin Barrier and Vaccination
The Skin Barrier and Vaccination group is led by Prof. Joke Bouwstra. One of the key functions of the skin is its barrier function, which is located in the uppermost layer of the skin, the stratum corneum. The stratum corneum consists of enucleated dead cells (corneocytes) embedded in a lipid matrix.…
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Research
Leiden University seeks to bring knowledge, academic top talents, and resources from Leiden and China together in mutually beneficial joint research projects that are content-driven, based on existing excellent research.
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Prediction of binding kinetics
Supervisor: Gerard van Westen
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Research
Combining different disciplines, researchers work together to formulate innovative solutions to societal problems.
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Research
The chemical industry must continue to innovate for a more sustainable, healthier society. The reseachers from the Leiden Institute of Chemistry (LIC) contribute by applying their knowledge to themes such as sustainability, energy and health.
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COMMUNITY: unraveling the regulatory networks in Streptomyces that switch on antibiotic production on demand
Through his project we will unravel the global regulatory networks that control gene expression in Streptomyces bacteria and allow them to properly respond to major changes in the environment; we will then harness this knowledge to activate and identify novel antibiotics
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Research
Research at the MCBIM group is comprised of the following research themes:
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Bioactive Molecules in Plant Sciences
Plant Sciences' contribution to the Bioactive Molecules research theme is to identify new plant bioactive molecules, and unravel their mechanisms of action in plant development or health, and the regulatory networks and (bio)synthetic pathways required for their production.
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Delivery of Biotherapeutics
The Delivery of Biotherapeutics research group is led by Prof. Matthias Barz and focusses on the synthesis and characterization of polypept(o)ids and their application in nanomedicine to improve existing therapies or enable novel diagnostic or therapeutic approaches.
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Cell Observatory: visualising structures of life
From molecule, to cell, to organism. The high-level drug research at the Cell Observatory aimes at reducing the spread of cancer and developing new medicines for tuberculosis.
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Knowledge of DNA repair in the fight against tumour cells
What is the most effective way to eliminate tumour cells? The DNA repair mechanism could play an important role in increasing the effectiveness of chemotherapy in the fight against cancerous cells. If we are to influence this mechanism, we need fundamental knowledge about how the mechanism works.