574 search results for “cancer drug resistance” in the Staff website
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Geographies of Repression and Resistance
Lecture, Teach-In Series on Palestine and Israel
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Babak Rezaeedaryakenari
Faculteit der Sociale Wetenschappen
s.rezaeedaryakenari@fsw.leidenuniv.nl | +31 70 800 3687
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Elizabeth (Liesbeth) de Lange
Science
ecmdelange@lacdr.leidenuniv.nl | +31 71 527 6330
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The molecular secrets of medicinal cannabis
Chronic pain, nausea or vomiting due to chemotherapy. If you suffer from such ailments, medicinal cannabis can be a godsend. Though a downside is that it can make patients high. Therefore, Leiden researchers from the Oncode Institute are investigating alternatives that do not make you high. In Nature…
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Nicolas Rodriguez Idarraga
Faculty of Humanities
n.rodriguez.idarraga@hum.leidenuniv.nl | +31 71 527 2727
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Bas ter Braak
Science
s.j.ter.braak@lacdr.leidenuniv.nl | +31 71 527 2727
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Marije Niemeijer
Science
m.c.niemeijer@lacdr.leidenuniv.nl | +31 71 527 6105
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Marcel Schaaf
Science
m.j.m.schaaf@biology.leidenuniv.nl | +31 71 527 4975
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Thomas Hankemeier
Science
hankemeier@lacdr.leidenuniv.nl | +31 71 527 4226
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Leiden researchers join forces against tuberculosis
About one and a half million people worldwide die each year from tuberculosis. For thirty years, therapy with antibiotics has been the same, while it takes far too long and can lead to resistant pathogens. Leiden researchers from four institutes are now joining forces to develop more effective and efficient…
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Discovery of BUB1 kinase inhibitors for the treatment of cancer
PhD defence
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Steffen Brünle
Science
s.bruenle@lic.leidenuniv.nl | +31 71 527 4544
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ERC-grant for Sebastian Pomplun to cure disease by controlling gene expression with synthetic transcription factors
Sebastian Pomplun receives an ERC starting grant of 1.85 million Euros in five years. He wants to develop synthetic transcription factors that can enter cells and activate or deactivate specific genes. For example to disrupt cancer-related processes or to trigger the production of an important missing…
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‘Pharmacogenetics will become part of patient care’
Does medicine make patients feel better or worse? We are getting better at predicting this from people’s DNA profiles, says Professor Jesse Swen. ‘It never fails to fascinate me how one DNA base pair can have such a huge effect on treatment with medication and the outcome.’
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Review on “Anticancer opportunities at every stage of chemokine function” is featured on the cover of TIPS
Last November, Dr. Natalia Ortiz, Martijn Bemelmans (MSc), and Prof. Laura Heitman published a review in Trends in Pharmacological Sciences (TIPS) on targeting the chemokine system in cancer (https://doi.org/10.1016/j.tips.2021.08.001). The review was written in collaboration with Prof. Tracy Handel…
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Regulation of signal transduction pathways by hypoxia in breast cancer subtypes
PhD defence
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To explore the drug space smarter: Artificial intelligence in drug design for G protein-coupled receptors
PhD defence
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Strategic advice
Communication
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Code of Conduct on Integrity
Anyone who comes into contact with Leiden University should be able to trust that we will act with integrity. The Code of Conduct on Integrity describes how we can work together to ensure that this is the case, whether in relation to research, interactions with students, purchasing or the use of University…
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Identification and characterization of viral Xrn1-resistant RNAs
PhD defence
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Search and Rescue: Tackling antibiotic resistance with chemistry
PhD defence
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On the nature of the right to resist
PhD defence
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Fighting gliobastoma brain tumours with two grants
Few researchers see potential in research on glioblastoma, an incurable brain tumour. Alexander Kros brought together colleagues who are up to the challenge. European research funder ERC recently made 10.6 million euros available, a year earlier NWO provided 3 million euros. ‘In six years, we certainly…
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Erik Danen new Dean of the Graduate School of Science
The Graduate School of Science starts 2024 with a new Dean. The Faculty Council appointed Erik Danen for the coming four years. He succeeds Eric Eliel, who has held the position since May 2020.
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‘Using real-world data to enhance our healthcare system’
On 16 May 2022, Professor Michel Wouters from the Department of Biomedical Data Sciences at the Leiden University Medical Centre (LUMC), will deliver his inaugural lecture titled ‘Quality of Cancer Care: why the real world matters’. Wouters will use the opportunity to describe how quality registries…
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Collaboration across borders: virtual learning between Leiden University College and Myanmar
Jyothi Thrivikraman set up a Virtual International Collaboration project with a university in Myanmar.
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Leiden University joins the Just Transitions for AMR Working Group
Leiden University joins the Just Transitions for AMR Working Group, an interdisciplinary team of social science and humanities researchers who are exploring ways to mitigate the growing threat of antimicrobial resistance in a just and equitable manner, with due consideration to the human rights of present…
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Evolution of Molecular Resistance to Snake Venom α-Neurotoxins in Vertebrates
PhD defence
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BRCA1-associated breast cancer: finding new weapons for an old villain
PhD defence
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Disrupting the transcriptional machinery to combat triple-negative breast cancer
PhD defence
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Cancer-induced somatic mutations in G protein-coupled receptors
PhD defence
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mRNA and Drug Delivery with Lipid-based Nanoparticles
PhD defence
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ASCL/LUCIR book presentation: Violent Resistance - Militia Formation and Civil War in Mozambique
Lecture
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Tom van der Wel
Science
t.van.der.wel@lic.leidenuniv.nl | +31 71 527 3527
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Serkan Aslan
Science
s.aslan@lacdr.leidenuniv.nl | +31 71 527 5919
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Madouc Bergers made her own enzyme inhibitors for her bachelor’s thesis
For her bachelor’s thesis, Molecular Science and Technology student Madouc Bergers synthesized her own molecule that can inhibit the breakdown of sugars. Although most students do not even manage to make one building block, Madouc made three. Partly because of this, she has been nominated for the Science…
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Studies on the Normative Force of Law: The Problem of 'Treatment Resistance'
Lecture
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Country Meeting: Violent Resistance - Militia Formation and Civil War in Mozambique
Lecture
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Life after the Grand Jamboree: Wrapping-up iGEM
‘A challenging rollercoaster, but also a very bonding and insightful experience,’ that’s how the team of iGEM Leiden 2022 wraps up their participation in the iGEM contest. The contest for synthetic biology climaxed during the Grand Jamboree in Paris. The team ended up in the top 10 of over 360 teams…
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Church and Politics, Humanity and Resistance: The Case of the Bethel Church Asylum in The Hague
Lecture
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environmental factors determining heterogeneity in preservation stress resistance of Aspergillus niger conidia
PhD defence
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Discovery of Antibiotics and Their Targets in Multidrug-Resistant Bacteria
PhD defence
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Resistance against the Achaemenid Empire: The Egyptian Rebellions of 521 and 487/86 BC
PhD defence
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ERC grant to further investigate next-generation antibiotics with reduced toxicity
The European Research Council (ERC) has awarded Nathaniel Martin a Proof of Concept (PoC) grant. With it, his group aims to make a dangerous but potent antibiotic less toxic. He receives €150.000.
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In conversation with the head of the rodent facility
Before patients can take a pill, scientists often spend years in the lab developing and testing a candidate drug. That often includes experiments with laboratory animals. As head of the rodent facility, Ilze Bot and her colleagues ensure that these experiments are conducted in an ethically responsible…
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IBL Spotlights - Development & Disease
Lecture
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Inclusive leadership for Depolarisation at Leiden University
Course, Course
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Data stewards
Do you have questions about data management? Please contact the data stewards:
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Superselective bonds light up
Rather than one key and one strong lock, biology often uses tens or hundreds of weaker links to bind parts together, such as cells membranes. This allows for selectivity and also reversibility: the binding can also be undone. Researchers first caught this phenomenon using spheres or colloids, and published…
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Race against time: Helping the Netherlands secure almost 20 million Pfizer vaccines
The whole world is waiting anxiously for sufficient supplies of coronavirus vaccines. As Launch Navigator at Pfizer, alumnus Dennis de Mik must help ensure that the Netherlands receives 19.8 million doses of the Pfizer/BioNTech vaccine. How is he going about this and how has his Bio-Pharmaceutical Sciences…