2,331 search results for “development disease” in the Public website
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Novel approaches to develop filamentous micro-organisms for enzyme production (FILAZYME)
Can we develop new enzymes and cell factories to upgrade current enzyme cocktails towards complete degradation of biomass?
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Development of a universal delivery system for tailor-made cancer vaccines
The potential of liposomal cancer vaccines
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Development of hyaluronan-based dissolving microneedle arrays for dermal vaccination
Dissolving microneedles are a subgroup of microneedle types that completely dissolve within the skin. During this dissolving process the vaccine, stored in the needle matrix, is released into the skin.
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Religion, Class, and the Postwar Development of the Dutch Welfare State
Religion, Class, and the Postwar Development of the Dutch Welfare State. Dennie Oude Nijhuis.
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European foreign policy in times of crisis: a political development lens
EU foreign policy has become increasingly politicised over the past years, amongst others as a consequence of the succession of crises. Crises may engender processes of crisis framing and contestation. This article focuses on how the policy demands being voiced in these processes of contestation are…
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Profile 6. Developing a parcel based historical GIS of the Netherlands
Historical geo data are gaining in importance. Provided that they are exactly geo referenced, they can be stored into a GIS and thus be combined with all kinds of maps (topographical, pedological, etc.) and datasets. This makes it possible to analyze historical developments in space and time on a detailed…
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Institutes
All research at Leiden University is organised into institutes. To do justice to the wide spectrum of research (and consequently teaching) that comes from these, you will find descriptions of all the Leiden institutes on these pages.
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Cholesterol metabolism in mouse models of atherosclerosis and adrenal steroidogenesis
Cholesterol influences many pathways, including serving as precursor for adrenal steroidogenesis. Imbalance of cholesterol levels has been implicated in several diseases including cardiovascular diseases and its underlying pathology, atherosclerosis.
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Why don't drugs make it to the market?
How can we extend the drug residence time to combat diseases more effectively?
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Visual analytics for spatially-resolved omics data at single cell resolution: Methods and Applications
The deeper understanding of an organism's pathology is important for developing treatments. Over centuries of systematic research, clinical researchers have demonstrated that the more information they acquire about the cellular properties and their organisation in the tissue, the better they can understand…
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CoSTREAM: Understanding Stroke and Alzheimer
The Horizon 2020 project CoSTREAM aims to improve our understanding of the co-occurrence of stroke and Alzheimer’s disease. It has long been known that both diseases share underlying causes, but their exact interaction or link is not fully understood. CoSTREAM combines multiple factors to identify and…
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Research
The current projects of the Molecular Physiology group focus on proteins of the endocannabinoid system, kinases and antibacterial targets. MSc- and BSc-students can contact Jessica van Krimpen-Kraaijenoord to apply for research internships.
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The historical development of the Dutch posture-verb progressive construction
On the 22nd of February, Ami Okabe successfully defended a doctoral thesis. The Leiden University Centre for Linguistics congratulates Ami on this achievement!
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Development of a Transgenic Mouse Model to Study the Immunogenicity of Recombinant Human Insulin
Mouse models are commonly used to assess the immunogenicity of therapeutic proteins and to investigate the immunological processes leading to antidrug antibodies. The aim of this work was to develop a transgenic (TG) Balb/c mouse model for evaluating the immunogenicity of recombinant human insulin (insulin)…
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T-CYCLE EPR: Development at 275 GHz for the study of reaction kinetics & intermediates
A difficulty of studies on chemical kinetics are the reaction time scales and detection of their intermediates.
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Topological decoding of biomolecular fold complexity
Biological polymers, including proteins and the genome, undergo folding processes crucial for their proper functioning. Even slight changes in the folding structure of these biopolymers can have significant implications, leading to the development of various pathological conditions, such as neurodegenerative…
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Novel receptor concepts
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Development of Cost efficient Advanced DNA-based methods for specific Traceability issues and High Level On-site applications
Schneider
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Systems pharmacology of the endocannabinoid system
What are the functions of the endocannabinoid system?
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LUMC signs international agreement on developing Advanced Therapy Medicinal Products
Skåne University Hospital, Lund University and Leiden University Medical Center will work together to expand their research, teaching and development relating to Advanced Therapy Medicinal Products. That is the essence of a Memorandum of Understanding signed at SciLifeLab near Stockholm on Wednesday…
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Medical Biochemistry
Medical Biochemistry is a section of the Leiden Institute of Chemistry at Leiden University. The section is headed by Prof. Dr. Hans Aerts.
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Data-Driven Machine Learning and Optimization Pipelines for Real- World Applications
Machine Learning is becoming a more and more substantial technology for industry.
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Ayokunu Adedokun
Faculty Governance and Global Affairs
a.b.adedokun@luc.leidenuniv.nl | +31 70 800 9503
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Rizal Shidiq
Faculty of Humanities
a.r.shidiq@hum.leidenuniv.nl | +31 71 527 8057
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Jacqueline Vel
Faculteit Rechtsgeleerdheid
j.a.c.vel@law.leidenuniv.nl | +31 71 527 7260
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Carolien Rieffe
Faculteit der Sociale Wetenschappen
crieffe@fsw.leidenuniv.nl | +31 71 527 3674
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Sjoerd Lopik
Faculteit Rechtsgeleerdheid
s.j.lopik@law.leidenuniv.nl | +31 71 527 2727
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Merijn de Bakker
Science
m.a.g.de.bakker@biology.leidenuniv.nl | +31 71 527 5043
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Jonathan Phillips
Faculteit der Sociale Wetenschappen
j.p.phillips@fsw.leidenuniv.nl | +31 71 527 2727
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Stephanus Huijbregts
Faculteit der Sociale Wetenschappen
shuijbregts@fsw.leidenuniv.nl | +31 71 527 1723
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Joost Visser
Science
j.m.w.visser@liacs.leidenuniv.nl | +31 71 527 2727
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Jochanan Veerbeek
Faculteit der Sociale Wetenschappen
j.veerbeek@fsw.leidenuniv.nl | +31 71 527 3399
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Horst Fischer
Faculteit Rechtsgeleerdheid
h.fischer@law.leidenuniv.nl | +31 71 527 2727
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Paul van den Broek
Faculteit der Sociale Wetenschappen
broekpwvanden@fsw.leidenuniv.nl | +31 71 527 2727
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Xiaoyang Zhong
Science
x.zhong@cml.leidenuniv.nl | +31 71 527 5148
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Jan Michiel Otto
Faculteit Rechtsgeleerdheid
j.m.otto@law.leidenuniv.nl | +31 71 527 7260
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Alette Vonk
Faculty of Humanities
a.p.vonk@hum.leidenuniv.nl | +31 71 527 2746
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Maximilian König
Faculteit der Sociale Wetenschappen
m.konig@fsw.leidenuniv.nl | +31 71 527 6619
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Bert Koenders
Faculty Governance and Global Affairs
a.g.koenders@fgga.leidenuniv.nl | +31 70 800 9506
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Lina van Drunen
Faculteit der Sociale Wetenschappen
l.van.drunen@fsw.leidenuniv.nl | +31 71 527 2727
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Mapping Medieval Malaria
This research project studies the distribution and impact of medieval malaria in the Netherlands.
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Knowledge development of secondary school L1 teachers on concept-context rich education in an action-research setting
This thesis reports on a study that examined the development of L1 teachers’ practical knowledge when they researched and implemented concept-context rich education in an action-research setting.
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Subang: An Indigenous Institution for Sustainable Community-Based Development in the Sunda Region of West Java, Indonesia
This study attempts to understand how indigenous community institutions pose an important role in sustainable community-based development, including the integration between local culture and development.
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About the programme
To maximise your personal development, we ensure tutorials are small-scale and staff members extremely accessible. In year one, you’ll have an average of 12 contact hours, half of which comprise lectures (in English) and the remainder tutorials (optionally Dutch or English).
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and Pains of Polysemy: Maritime Trade, Averages, and Institutional Development in the Low Countries (15th–16th Centuries)
The Power and Pains of Polysemy: Maritime Trade, Averages, and Institutional Development in the Low Countries (15th–16th Centuries) investigates the development of General Average and other so-called Averages in the Low Countries on the eve of the early modern period, showing how the various varieties…
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Surya Tjandra defends his Ph. D thesis ‘Labour Law and Development in Indonesia’ on 4 February 2016
In his thesis Tjandra analuses the development of labour law in Indonesia. He focusses on the developments after the fall of the Soeharto regime (1998), the so called reformasi period.
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Animal sciences and health
In the research theme ‘Animal Sciences and Health’, we work with various animal species to gain insights into fundamental biological processes in both animals and humans.
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Data Analytics and Management
Our group is part of the Metabolomics and Analytics Centre where we accompany the data from its acquisition all the way to the publication of identified associations and biomarkers for a range of human diseases. The generated data of the metabolic measurements are assessed using an in-house quality…
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Develop a methodology for assessing the effective dose of nanomaterials for environmental risk assessment purposes
How to make a quantitative assessment of the relative contribution to toxicity of ions and particles? Is the toxicity of nanoparticles related to their size or shape? Which physicochemical property of nanoparticles is an appropriate dose metric of nanoparticles?
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RE-PAIR: Unravelling the Impact of Emotional Maltreatment on the Developing Brain
What role do parent-child interactions play in the development, maintenance and treatment of depression in young people?