1,068 search results for “treatment” in the Public website
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Novel Immune Cell-Based Therapies for Atherosclerosis
Promotor: Prof.dr. J. Kuiper, Co-Promotor: S.C.A. de Jager
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Strategy
The Division of Systems Pharmacology and Pharmacy (SPP) aims to develop precision medicine approaches to characterize and predict variation in treatment response and enhance translational drug development strategies.
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Sybil-AA: Systems Biology of Alcohol Addiction
The Horizon 2020 project Sybil-AA (Systems Biology of Alcohol Addiction) focuses on modeling and validating disease state networks in human and animal brains for understanding pathophysiology, predicting outcomes and improving therapy in alcohol addiction. Alcohol addiction, the most severe form of…
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The diverse roles of integrin α3β1 in cancer: Lessons learned from skin and breast carcinogenesis
In this thesis, we aim to shed light on the diverse and often opposing roles of integrin α3β1 in cancer.
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Biorythm and brain dysfunction
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Systemic Treatment in Malignant Mesothelioma: Treat it or Leave it
PhD defence
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Quantitative Pharmacology
The Quantitative Pharmacology group headed by Coen van Hasselt focusses on the application of state-of-the-art quantitative pharmacometrics and systems pharmacology modeling combined with translational experimental models to develop personalized treatment strategies for antibiotics and to combat antimicrobial…
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High-Throughput Metabolomics
Development of Comprehensive and High-throughput metabolomics techniques and Clinical applications of (pharmaco)metabolomics
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Translational Immuno-Pharmacology
The Translational Immuno-Pharmacology group works on translating the efficacy of anti-infective therapy from preclinical (e.g. in vivo) to clinical, and is led by Rob van Wijk. Infectious diseases, such as tuberculosis, are in constant need of new therapies that work better, faster, and with less risk…
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Fundamental research: Underlying mechanisms of disease and health
To make the right clinical decisions or develop effective diagnostic tests and treatments, it is important to understand the underlying mechanisms of a condition or behavior.
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Hypermarker
Developing a clinical decision support tool that will make it easier for clinicians to personalise the treatment for patients with high blood pressure. The team is using AI, deep learning methods and patient cohort data from 11 European countries.
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Refining individualized treatment in older patients with breast cancer
PhD defence
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Strategies to optimise the treatment of community-acquired pneumonia
PhD defence
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New Approaches to Imaging and Treatment of Ocular Melanoma
PhD defence
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Patient readiness for shared decision making about treatment
PhD defence
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Updates in Molecular Diagnosis and Targeted Treatment of Thyroid Neoplasia
PhD defence
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Optimizing antiseizure medication treatment in glioma patients with epilepsy
PhD defence
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Prosthetic Joint Infection, new diagnostic and treatment strategies
PhD defence
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Quality assessment and multi modalty in gastric cancer treatment
PhD defence
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Discrepancies in diagnoses and treatment of type B ankle fractures
PhD defence
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Towards personalized treatment for high risk endometrial cancer
PhD defence
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Substrate Identification and Treatment of Right Ventricular Tachycardia
PhD defence
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Female workers Tesco Stores win case on unequal pay
Female workers at Tesco Stores, a chain of supermarkets in the UK, brought a case to the European Court of Justice claiming they received unequal pay for doing work of equal value to that of their male colleagues.
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Evidence-based treatment of central serous chorioretinopathy
PhD defence
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Leiden University Medical Center
The Leiden University Medical Center (LUMC) is committed to improving healthcare and the health of individuals. The LUMC staff put this mission into practice on a daily basis with their leading research, cutting-edge teaching and optimal, innovative healthcare.
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Research
Tuberculosis causes 1.5 million deaths yearly and anti-tuberculosis therapies are threatened by emergence of drug resistance. Development of innovative drug combinations should be accelerated with the use of translational pharmacological models. Moreover, host-directed therapies (HDT), which stimulate…
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Topic: Psychopharmacology in Health and Medical Psychology
In this research line, the role pharmacological agents and neurochemcial processes play in behavior and cognition is examined with a particular focus on pain, placebo and nocebo effects and intensive care treatments.
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SFA of PVC in Sweden
In this study the flows of PVC and its additives through the Swedish Society were followed from the cradle to the grave (from production to waste treatment).
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Challenged by cognition
Toward optimal measurement and greater understanding of youth cognition in school refusal and cognitive behavioural therapy outcome
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Novel regulators of prostate cancer stem cells and tumor aggressiveness
Promotor: R.C.M. Pelger Co-Promotor: G. van der Pluijm
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Education
The group is involved in training in areas of diagnostic skills, treatment/prevention/intervention, neuropsychological assessment, behavioral observations, clinical interviewing, knowledge of intellectual disability, autism, ADHD, psychosis and aggression.
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Our Research
From basic science to real-world interventions
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Efficacy of Self-management training in adolescents and adults with Klinefelter syndrome (XXY)
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“Special Needs by Placebo”: Programme to Advise, Normalize And Control its European Administration (PANACEA)
While many healthcare professionals indicate that they frequently use placebo effects and their mechanisms, there is little formal training on how to deal with placebo and nocebo effects in clinical practice. This project aims to address this gap between scientific knowledge on placebo and nocebo effects…
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Cancer pathogenesis and therapy
With cancer, a person’s body cells grow uncontrollably. Putting together a detailed picture of how this comes about makes it possible to develop efficient therapies. Researchers at the Leiden University Medical Centre (LUMC) and Leiden University are working together to gain a better understanding…
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School non-attendance in students with intellectual disability
Are the types of school non-attendance which have been evidenced in typically developing youth also found among children and adolescents with an intellectual disability (ID)? If so, which types are most prevalent and thus in greatest need of attention, and what factors (child, family, school/environmental)…
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Control theory methods for quantitative systems pharmacology models
Following their application to system biological models, control theory techniques have further potential to aid in the understanding and application of quantitative systems pharmacology models.
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RE-PAIR: Unravelling the Impact of Emotional Maltreatment on the Developing Brain
What role do parent-child interactions play in the development, maintenance and treatment of depression in young people?
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Research projects
An overview of research themes and projects at ABS.
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Topic: Persistent physical symptoms
Persistent somatic symptoms are long term symptoms that lack a clear medical explanation. These symptoms have a high prevalence where most people know someone who experiences such symptoms or they experience such symptoms themselves. Symptoms can vary greatly in and between people. While one person…
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Redemption in the Old Babylonian period: texts, archives, practice
Stephen Moore defended his thesis on 26 May 2020.
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Topic: Work and health
The research connected to this topic is related to Work and health.
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Education
The Clinical Psychology Educational Programme aims to provide specialized knowledge of psychopathology, diagnostic and treatment skills and related scientific research.
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Evaluation of synergistic effects of Chinese herbal medicine and natural compounds on cancers
What are the biological effects of Chinese herbal medicine in regulation of cancer cell metastasis?
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Developing metabolomics for a systems biology approach to understand Parkinson's disease
Neurodegenerative diseases, including Parkinson’s disease (PD), are increasing in prevalence due to the aging population. Despite extensive study, these diseases are still not fully understood and the lack of personalised treatment options that can target the cause of the diseases, rather than the symptoms,…
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Unraveling temporal processes using probabilistic graphical models
Real-life processes are characterized by dynamics involving time. Examples are walking, sleeping, disease progress in medical treatment, and events in a workflow.
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Severe behavioral and emotional problems, special education and youth care
Which educational and child welfare interventions offer optimal opportunities for positive development to children with severe behavioral and emotional disorders.
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Cancer chess: molecular insights into PARP inhibitor resistance
The clinical potential of applying synthetic lethality to cancer treatment is famously demonstrated by the BRCA1/PARP1 paradigm: a tumor specific defect in BRCA1 – a component of the DNA double-strand break (DSB) repair pathway homologous recombination (HR) – results in a remarkable sensitivity to PARP1…
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Clinical Psychology
Clinical psychology is a discipline concerned with the application of psychological science to the assessment and treatment of mental disorders.
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Brave Steps
A step-by-step approach to building confidence in anxiety-prone young children.