1,397 search results for “treatment” in the Public website
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Healthy ageing
The elderly accept may minor discomforts like stiffer muscles and getting tired more quickly, but they do want to go to their children's birthdays independently. Preventive elderly care helps people with that. The goal is to let people grow old while maintaining their self-reliance and independence…
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The rights of the developing child
As children learn, develop and acquire more skills, their legal position also changes. Professor of Children’s Rights Ton Liefaard works closely together with Leiden social sciences researchers to shed light on these growing capacities and their implications for our legal system. ‘Our ideas about children’s…
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Leiden Academic Centre for Drug Research
Drug development is a complex process in which many parties work together. Every day, the researchers at LACDR devote their energies to developing drugs that are new, better, more efficient and easier to produce. And thus to the millions of patients who know all too well why this research in Leiden…
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Leiden Early Drug Discovery & Development
Despite recent advances in medicine, many devastating disorders like cancer and cardiovascular, neurodegenerative and infectious diseases still lack effective treatments. In order to address this challenge, we, as scientists from Leiden University, joined hands in the LED3 network. LED3, for Leiden…
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Early recognition and intervention of stress and anxiety in the classroom
How can we facilitate the early recognition of stress and anxiety in the classroom and collaborate with schools in providing low-threshold interventions?
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AI in Neuroscience: Development of Methods to make Personalized Predictions for Migraine and Stroke from E-Health Sensor Data
The research of this PhD project can be subdivided into two main disease areas: migraine and stroke. For both we will be investigating how artificial intelligence (AI) and machine learning (ML) techniques can be used to study these afflictions, their (early) detection, and their potential treatment.
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Topic: Music and health
Music can affect how we feel, think, and behave. But how do we learn about the specifics of people's responses to music so that we can apply this to health and well-being? By looking at characteristics of the music, as well as the differences between listeners, we hope to better understand as well as…
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Development of new antibiotics from plant-originated products
Utilization of plant-originated products as new antibiotics
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Light-activatable ruthenium-based anticancer prodrugs
Can light-activatable ruthenium compounds be used as a more selective anticancer treatment?
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A comparative perspective on perceived legitimacy: evaluating authorities in democratic and no-democratic contexts
Does the political context (e.g., democracy vs. authoritarianism) influence what makes people perceive authorities as legitimate?
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Imperative in the Rigveda
This work sets out to investigate the form and function of the imperative in the Rigveda. The morphology (and, where relevant, etymology), syntax and semantics of the imperative are covered.
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Knowledge of DNA repair in the fight against tumour cells
What is the most effective way to eliminate tumour cells? The DNA repair mechanism could play an important role in increasing the effectiveness of chemotherapy in the fight against cancerous cells. If we are to influence this mechanism, we need fundamental knowledge about how the mechanism works.
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Workshops & Demo's
During the Leiden Science Family Day, you can take part in various workshops. You can also watch various demonstrations. Where will you go?
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Determining the kinetic profile of ENT1 inhibitors
Supervisor: Anna Vlachodimou
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Topic: Movement and mental functions
Our ability to learn and control movements is essential for engaging in goal-directed behaviour. From buttoning your shirt and driving a car, to cooking dinner and brushing your teeth -- our actions in daily life rely on this ability.
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Leiden Science Young Talent Award
The Leiden Science Young Talent Award is awarded yearly to a student who completed their bachelor’s degree with an excellent thesis.
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Topic: Stress and stress-related disorders
The precise psychobiological mechanisms leading to chronic physiological stress responses have not been sufficiently explained, although stress is a major risk factor for disease and early death. A problem for conventional stress theory is that most of these responses seem to occur in situations without…
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New imaging technology to assess early drug success
Human and animal cells are very complex: very different chemical processes are going on at the same time, but they are separated from each other because the cells are divided in compartments. These compartments may also have a profound effect on the potential efficacy of therapeutics, because the drug…
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Studies on molecular basics of metabolic syndrome in zebrafish
The research described in this thesis has, using the zebrafish as a model system, shed new light on the intricate relationship between TB and DM2, in particular on the role of leptin, SHP-1 and glucocorticoids.
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Leiden Academic Centre for Drug Research
The Leiden Academic Centre for Drug Research (LACDR) is a centre of excellence for multidisciplinary research on drug discovery and development.
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Imaging & Intervention (MSc)
This specialisation focuses on two important trends in health care: early diagnosis and developing the most targeted patient-specific treatment possible with the shortest possible recovery time and minimal side effects.
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Maartje van der Woude on discrimination at border controls
In its ruling this week, The Hague Court of Appeal made short work of how the Dutch Border Police allow the colour of a person’s skin to be taken into account when selecting people to check. According to Maartje van der Woude, this ruling reaches far beyond the border police. ‘This is a problem for…
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Peter Rodrigues ‘The boundaries for discrimination have shifted’
The judicial authorities are looking into the possibilities for prosecution for the slogans that were projected on the Erasmus Bridge in Rotterdam on New Year’s Eve. Not an easy task, according to legal experts. When do we consider something to be ‘discrimination’?
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Peter Rodrigues on discrimination case Giethoorn: 'Incorrect assessment by police'
The Public Prosecutor’s Office Oost-Nederland, the Police in Oost-Nederland and the municipality of Steenwijkerland failed in their handling of a case involving discrimination in Giethoorn. This is the opinion of experts, including Professor Peter Rodrigues, in Dutch investigative journalism programme…
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Abstracts
We warmly welcome late abstracts for Poster Communications! Late abstracts submission closes on the 1st of August 2022.
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Education
Within the bachelor's program of Education and Child Studies, we include the minor Kindermishandeling en Verwaarlozing: een levensloopperspectief and several other courses.
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Health Data Science special interest group
Health Data Science Leiden University
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About Healthy Society
The research area "Health and well-being in a healthy society" studies the institutional and behavioral factors that play a role in health and well-being for people of all ages.
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Watañi lāntaṃ: Khotanese and Tumshuqese Loanwords in Tocharian
Contacts between Tocharian A and B and Khotanese and Tumshuqese, four languages once spoken in today’s Xīnjiāng Uyghur Autonomous Region in Northwest China, lack a comprehensive treatment and are still a controversial topic. This work contains the first systematic investigation of the matter from a…
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Imaging of alkyne-functionalized ruthenium complexes for photoactivated chemotherapy
In photoactivated chemotherapy (PACT), a biologically active compound is caged by a light-cleavable protecting group.
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Social Anxiety and Specific Phobia in Youth
From basic science to real-world interventions
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Education
Social Policy is increasingly incorporated as a subject of European law. The Social Dialogue with labour and management organisations leads to agreements that can be transformed into Directives of the Council
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Pharmacodynamics of analgesics and sedatives in neonates and infants
In neonates and infants, body size, enzyme pathways, and expression and function of receptors and (target) proteins are still developing.
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Navigation Lab Leiden
The Navigation Lab Leiden is part of the department of Health, Medical and Neuropsychology at Leiden University, and led by Ineke van der Ham We study human spatial cognition, with an emphasis on navigation ability. We examine factors that can explain for individual differences, such as gender and age.…
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Development of novel metabolomics and systems pharmacology methods
We are developing biology-driven platforms to measure metabolites based on liquid chromatography-mass spectrometry (LC-MS), gas chromatography-MS (GC-MS), and capillary electrophoresis-MS (CE-MS).
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Potentiation of Gram-positive specific antibiotics against Gram-negative bacteria through outer membrane disruption
Extending our current arsenal of antibiotics is key to staying ahead in the arms race between humans and resistant bacteria.
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Mental health and the law
Mental health issues in the Dutch court: The criminal court as a border guard between the regular Mental Health System and the Criminal Justice system?
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Experiences with the Liverpool care pathway for the dying patient in nursing home residents
The Liverpool care pathway for the dying patient (LCP) is a multidisciplinary tool developed for the dying phase for use in palliative care settings. The literature reports divergent experiences with its application in a nursing home setting related to its implementation and staff competencies. The…
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Lab facilities Health, Medical and Neuropsychology
Psycho-physiological studies for health and disease.
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Applications of multisource data-based dynamic modeling to cell-cell signaling and infectious disease spreading
The emergence of complex diseases resulting from abnormal cell-cell signaling and the spread of infectious diseases caused by pathogens are significant threats to humanity. Unraveling the dynamic mechanisms underlying cell-cell signaling and infectious disease spreading is crucial for effective disease…
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Construction and exploration of modular goldnanoparticles for glycan-based immune-interventions of worm infections
Chiodo
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Quantitative Clinical Pharmacology
The Quantitative Clinical Pharmacology group is led by Prof. Dr. Catherijne Knibbe. Her research group aims to define how to adjust a drug dose in special patient populations such as (prematurely born) neonates or children, obese individuals or critically ill patients. Through combining the statistical…
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Characterization of Cell-based medicinal products (CBMPs)
Cell-based medicinal products (CBMPs) show great promise when it comes to the treatment of genetic disorders. However, there is limited knowledge about CBMP stability during their production, storage, and administration to patients. The main focus of my research is the characterization of CBMPs using…
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Translational Neuroscience
Within the LUMC medical research profile Translational Neuroscience innovative multidisciplinary research is performed on a number of severe disorders of the brain, nerves and muscles.
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A novel biofilm for skin barrier repair of patients with atopic eczema
Atopic eczema is a skin disease with increasing incidence currently affecting 25% of the paediatric population. In atopic eczema the skin barrier function is reduced. This barrier is formed by the outermost layer of the skin called the stratum corneum (SC). The SC consists of terminally differentiated…
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Hye Kyong Kim
PhD at the Natural Product Laboratory, Institute of Biology, Leiden University - the Netherlands
- About this minor
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Using zebrafish to target the Achilles’ heel of cancer
Exploiting metabolic vulnerabilities to identify anticancer compounds in zebrafish synthetic lethality screens.
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Bio-organic Synthesis
The research in the Biosyn group is focused on the design, synthesis and function of the four major types of biomolecules: nucleic acids, carbohydrates, peptides and lipids and hybrid structures thereof. These biomolecules and their derivatives are used in drug discovery and chemical biology, to develop…
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Development of life cycle assessment for residue-based bioenergy
What are the key issues in conducting LCA of bioenergy systems? What is the environmental sustainability status of second generation bioethanol? How much would the final results of biogenic carbon neutrality assumptions deviate from the true values based on a complete inventory? How to assess the impact…