698 search results for “acoustic signals” in the Public website
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Calcium-dependent regulation of auxin transport in plant development
The plant hormone auxin regulates plant growth and development through polar cell-to-cell transport-generated maxima and minima. PIN FORMED (PIN) auxin efflux carriers determine the direction of this auxin flow through their asymmetric placement on the plasma membrane (PM).
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Nanomaterial safety for microbially-colonized hosts: Microbiota-mediated physisorption interactions and particle-specific toxicity
The external tissues of plants and animals are colonized by microbial communities termed microbiota. When organisms are exposed to environmental pollutants, these substances will therefore encounter microbiota at the exposure interface.
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Precarious Modernities
Assembling State, Space and Society on the Urban Margins in Morocco
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The Ecology and Evolution of Microbial Warfare in Streptomyces
The soil-dwelling, filamentous bacteria of the genus Streptomyces are renowned for their production of useful secondary metabolites including antibiotics. The work described in this thesis provides new insights on the role and regulation of antibiotic production and resistance in these bacteria.
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Evolution & Biodiversity
Evolution & Biodiversity is one of the four research themes of the Institute of Biology Leiden.
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Gibbs processes and applications
Gibbs processes, g-measures, fuzzy Gibbs states
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Spreading the Fire: Why is Pyroptotic Cell Death Contagious?
The word ¨pyroptosis¨ can be understood as ¨fiery falling¨, which describes the bursting of pro-inflammatory signals from the dying cell. Our observations indicate that pyroptosis also ¨spreads like wildfire¨ and once a cell dies via pyroptotic cell death, neighbouring cells are more prone to die as…
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Medical Biochemistry
Medical Biochemistry is a section of the Leiden Institute of Chemistry at Leiden University. The section is headed by Prof. Dr. Hans Aerts.
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Languages of Islam and Christianity: Institutional Discourses, Community Strategies and Missionary Rhetoric
On February 20th, Gulnaz Sibgatullina succesfully defended her doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Gulnaz on this great result.
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Forensic linguistics and speech evidence
Investigating specific language and speech behaviour of people.
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Endocannabinoids in health and stress
How does the endocannabinoid system in the zebrafish function at the molecular and phenotypic levels and how is it linked to the stress axis?
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The unexpected norm-setters: Intelligence agencies in cyberspace
Ilina Georgieva published an article in the journal Contemporary Security Policy on the norm-setting role of intelligence agencies.
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Cellular Forces: Adhering, Shaping, Sensing and Dividing
Promotor: Prof.dr. T. Schmidt
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Making the invisible visible: paramagnetic NMR and the transient protein complex
Promotor: Prof.dr. M. Ubbink
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Rebel Legal Order, Governance and Legitimacy: Examining the Islamic State and the Taliban Insurgency
This article explores how ISIS and the Taliban have fostered support through their parallel legal systems.
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Integrating cellular and tissue dynamics with cell fate decisions through computational modeling
There is a need for alternative methods to replace, reduce and refine (3R) animal experimentation. Combining experimental data from high-throughput in vitro studies with in silico modeling is a promising approach to unravel the effect of chemicals on living cells and to gain a better understanding of…
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Bayesian Inference for Gaussian Models
This dissertation studies the Asymptotics of Bayesian nonparametric inference for Gaussian linear models.
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Cognitive Psychology
Cognitive psychology is the study of cognitive functions such as attention, memory, consciousness, emotion, language and action control. The goal is to understand the complex relationships between brain, mind and behavior.
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Dynamics and radiation from tidal disruption events
When a star gets too close to a supermassive black hole, it is torn apart by strong tidal forces in a tidal disruption event (TDE).
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The Limited Impact of Reference Groups’ Symbolic Gender Representation on Willingness to Coproduce
This article discusses the impact of symbolic gender representation on the willingness of citizens to coproduce.
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Discovery of a NAPE-PLD inhibitor that modulates emotional behavior in mice, Nat. Chem. Biol. 2020
N-acylethanolamines (NAEs), which include the endocannabinoid anandamide, represent an important family of signaling lipids in the brain. The lack of chemical probes that modulate NAE biosynthesis in living systems hamper the understanding of the biological role of these lipids.
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Performance information and issue prioritisation by political and managerial decision-makers: A discrete choice experiment
This article explores the concept of issue prioritisation within the context of public administration research, focusing on decision-making processes.
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Genomics applications of nanopore long-read sequencing for small to large sized genomes
In this thesis I highlight the applications of Oxford Nanopore Technologies (ONT) sequencing. This technique is a relatively new approach in the sequencing field, where nanopores are embedded in a membrane, DNA molecules are pulled through nanopores and an electrical current serving as the sequencing…
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Call-induced water ripples put frogs at risk of bat predation
Wouter Halfwerk and colleagues from Panama and the US published a paper on multisensory communication in Science. The authors provide compelling data on the consequences of multisensory perception on signal evolution in tropical frogs.
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‘Vestito a ponti d’oro e a cento corde in seno’: history, repertoire and playing techniques of the Italian salterio in the eighteenth century
This research aims to fully recall these lost sound aspects of the eighteenth century and is, therefore, a study that passionately advocates the diversity of musical experience in the context of historical performance practice.
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PROGENY
How do you make a technology sustainable that does not even exist yet? Well, by bringing together an interdisciplinary team of pioneering European experts right at the start and paying attention to sustainability right from the development phase.
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A YEAR IN THE LIFE OF THE SONOLOGY ELECTROACOUSTIC ENSEMBLE
Research report January 2020. Supported by the lectorate ‘Music, Education and Society’, research group ‘Making in Music’, Royal Conservatoire The Hague
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Noise pollution affects marine life worldwide
Man-made sounds in and around the oceans stress marine life and have an impact on marine species and ecosystems by changing the underwater acoustic climate. Hans Slabbekoorn from the Institute of Biology Leiden pleads for technical solutions to mitigate problems of noise pollution. Science review paper…
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Mazène Hochane and Xueying Fan win LION Image Award 2018
Mazène Hochane and Xueying Fan have won the fourth annual LION Image Award. They created a detailed colour image of a human kidney in development.
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IAFPA research grant for Willemijn Heeren and Lei He
Willemijn Heeren has, together with dr. Lei He (Department of Linguistics, Tübingen & Center for Forensic Phonetics and Acoustics, Zürich), received a research grant from the International Association for Forensic Phonetics and Acoustics to start a pilot project on “Between-speaker variability in dynamic…
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Third national Bioacoustics day in Zeeland
On the 15th of October, IMARES and IBL co-organized a symposium on underwater acoustics related to research on fish and marine mammals.
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Detection of Archaeological Sites in High Resolution Satellite Images
In this project we develop algorithms to automatically detect a particular type of archaeological sites in satellite images of the Alps.
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Inflammafish: Cross-talk between inflammation and autophagy in tuberculosis
Effective host defence against tuberculosis bacteria depends on a properly balanced level of inflammation. The Inflammafish project uses zebrafish larvae to study how autophagy controls this inflammation and vice versa.
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Consonant and lexical tone interaction: Evidence from two Chinese dialects
On the 4th of June, Menghui Shi successfully defended a doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Menghui Shi on this achievement!
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Anticancer compounds from actinomycetes
How can we find novel natural products from Actinomycetes that act as growth modulators on mammalian cells? Can we harvest and develop the potential of these novel compounds for industrial and medical biotechnology?
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High-throughput simulation studies of angiogenesis - Reverse engineering the role of tip cells and pericytes in vascular development
Promotor: Prof.dr. R.M.H. Merks
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Vital Art: Transgender Portraiture as Visual Activism
In what ways can visual art play a vital role in countering the discriminating stigma experienced by transgender communities?
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A time-space translation mechanism for patterning the vertebrate anteroposterior axis
My PhD project studies how the temporally sequential Hox gene expression is regulated during head-tail patterning of the frog embryo.
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Development & Disease
Development & Disease is one of the four research themes of the Institute of Biology Leiden.
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Grants & Awards
Grants awarded to molecular physiology research
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Role of non-homologous end-joining in T-DNA integration in Arabidopsis thaliana
Promotor: P. J. J. Hooykaas Co-promotor: B. S de Pater
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Towards High Performance and Efficient Brain Computer Interface Character Speller: Convolutional Neural Network based Methods
A P300-based Brain Computer Interface character speller, also known as P300 speller, has been an important communication pathway, under extensive research, for people who lose motor ability, such as patients with Amyotrophic Lateral Sclerosis or spinal-cord injury because a P300 speller allows human-beings…
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Yes/no question-marking in Italian dialects - A typological, theoretical and experimental approach
This dissertation provides an account of polar questions in Italian dialects from a typological, theoretical and empirical perspective.
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Unraveling cross-presentation pathways using a chemical biology approach
Is it possible for sugar patterns on cells to activate the immune system to combat cancer?
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Caught off guard? Evaluating how external experts in Germany warned about Russia’s war on Ukraine
This article reviews how external expertise supports intelligence production and crisis decision-making with Germany's response to the Russio-Ukrainian war.
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The role of 14-3-3 proteins in ion homeostasis in the yeast Saccharomyces cerevisiae
We aim to understand ion homeostasis in the model eukaryote S. cerevisiae.
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A₃ adenosine receptor allosteric modulator induces an anti-inflammatory effect: in vivo studies and molecular mechanism of action
Source: Mediators Inflamm (2014)
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The early stress response of jasmonic acid in cell suspension cultures of Catharanthus roseus
In order to gain a better insight into the basis of the rapid jasmonic acid (JA)-mediated stress response, an integrated approach using a targeted high-resolution mass spectrometry-based (HRMS) platform, was conducted to monitor the metabolism of JA using the model system of cell suspension cultures…
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Painting with starlight : optical techniques for the high-contrast imaging of exoplanets
This thesis describes the development and validation of new high-contrast imaging techniques, with the ultimate goal of enabling the next generation of instruments for ELT-class telescopes to directly image Earth-like extra-solar planets orbiting around nearby stars.
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Drug Discovery & Safety
In the research programme Drug Discovery & Safety, we are interested in the efficacy and safety of new drugs and novel means to decipher these aspects. Hence, we employ advanced imaging and high-throughput screening techniques next to computational approaches such as chem- and bioinformatics.