415 search results for “blood vessels” in the Public website
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New cell therapy facility at Leiden Bio Science Park
American pharmaceutical company Bristol Myers Squibb will be building a new (CAR-T) cell therapy facility in the Oegstgeest part of the Leiden Bio Science Park. The company will manufacture and develop CAR T-cell therapy for patients with blood cancer (leukaemia), for example.
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First clinical trial with genetically modified malaria vaccine completed
In an innovative study, Radboudumc and LUMC jointly tested a candidate vaccine based on a genetically weakened malaria parasite. The results of this clinical trial, published in Science Translational Medicine, show that the vaccine is safe and elicits a defense response against a malaria infection.
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The Evolution of Fangs, Venom, and Mimicry Systems in Blenny Fishes
Venomous animals serve as models for a variety of mimicry types. Michael Richardson (IBL) and his international colleagues find that a group of fishes (called fangblennies) evolved venom after the origin of their venom-delivering fangs.
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Liesbeth de Lange wins Lewis B. Sheiner Career Prize
Pharmacologist Liesbeth de Lange has won the Lewis B. Sheiner Lecturer Award from the International Society of Pharmacometrics (ISoP). As Professor of Predictive Pharmacology she is working, among other things, on a mathematical model that can predict drug concentrations in the brain. On the occasion…
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2012 Spectacular finds Fieldschool 2012 Anse Trabaud
In June and July 2012 a Leiden Fieldschool was conducted at the late pre-Columbian site of Anse Trabaud in southeastern Martinique. High levels of preservation and waterlogged contexts revealed spectacular finds.
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Europa Institute participates in Odysseus Summer School
Europa Institute staff members Jorrit Rijpma, Melanie Fink and Kristof Gombeer participated last week in the Odysseus Network’s Summer School on EU Immigration and Asylum Law and Policy (Brussels, 2-13 July).
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How to determine medication dosages for premature babies
Premature babies almost always require treatment with medication. Doctors usually determine the dosages based on data from children who were not born prematurely, while preterm infants often develop differently. Medication researcher Aline Engbers investigated three commonly used drugs, focusing on…
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How do children's kidneys eliminate drugs?
What dose of medicine do you give a child? That depends to a large extent on how quickly their kidneys remove the drug from the blood. For ethical reasons it is impossible to measure this directly in little patients. PhD candidate Sinziana Cristea combined different types of modelling and lots of data…
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Fetal laser surgery as a last resort
For his dissertation, Joost Akkermans searched for areas of improvement for delicate fetal laser surgery with Twin Transfusion Syndrome (TTS). This syndrome occurs in the Netherlands 60 to 70 times a year among single-egg twins sharing one placenta. Treatment is possible, but not without risk. Inaugural…
- Laboratory for Ceramics Studies
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Martinique
Since 2005 Leiden fieldschools have maintained local collaborations with archaeologists on Martinique carrying out surveys and excavations.
- Week 3: 22-29 January 2017
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Bordering Up: Regulating Mobility Through Passes, Walls and Guards
Bordering Up: Regulating Mobility Through Passes, Walls and Guards
- Week 6: 11–17 February
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Deep sea research with microphone
‘Even at the deepest point in the ocean you can still hear the noise from boats,' says biologist Hans Slabbekoorn. ‘And that's while sound is the most important means of communication for underwater life.' What is the effect of all that underwater noise on fish and other animals? Slabbekoorn is on board…
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Newly discovered gene regulates balance of ‘bad cholesterol’
In a publication in Science, Noam Zelcer from the Division of Biopharmaceutics describes a previously unrecognized pathway to regulate LDL-cholesterol levels. He is also able to modulate this pathway. This opens the possibility for complementing and improving the efficacy of statins: A class of drugs…
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Direct relationship between depression and inflammation called into question
Depression has traditionally been linked to increased inflammation. Innovative research by psychologist Eiko Fried refutes this popular assumption. He shows that specific depression symptoms such as sleeping problems explain this relationship. Publication in Psychological Medicine .
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New project funded to study Alzheimer's disease
Researchers from Leiden University will develop a new approach to study the biomarkers of Alzeimer’s disease. This approach focusses on the molecular messengers of the cells. The project, led by Thomas Hankemeier and coordinated by Yuliya Shakalisava (Leiden Academic Centre for Drug Research, LACDR),…
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Leiden University Medical Center
In the Leiden University Medical Centre (LUMC) we strive to improve health care and the health of people.
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Cultures of Collecting: The Leiden Anatomical Collections in Context
The general aim of the project is a description and analysis of the Leiden anatomical collections from a humanities perspective. The project investigates how historical and cultural practices and concerns have shaped anatomical preparations and how exhibitions of the anatomical body have informed cultural…
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Veni subsidies for sixteen Leiden researchers
Sixteen researchers at Leiden University have received a Veni award from the Netherlands Organisation for Academic Research (NWO). This award offers promising young researchers the opportunity to further develop their ideas for a period of three years.
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€10.6 million for innovative toolboxes to tackle brain cancer
Researchers at the Universities of Amsterdam (Uva) and Leiden together with the Netherlands Cancer Institute and Oncode Institute have received a €10,6 million ERC Synergy Grant to develop innovative therapeutic approaches to target glioblastoma. This is a deadly primary brain tumour for which no curing…
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The magic of liquid helium: this person makes ice-cold research in Leiden possible
White clouds of ice-cold gas flowing across the floor. Magical, but be careful not to freeze your fingers off. We are of course talking about liquid nitrogen and helium. You may have seen the spectacular Freezing Physics science show by the student organisation Rino. But did you know that this commodity…
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Melanie Fink and Emma Irving present at ‘New Female Voices in Academia’ – Book Launch ‘Frontex and Human Rights'
On 11 February 2019 the Women in International Law Network, established in 2017 as an informal network for midlevel to senior female officials, experts, advisers and academics working in international law in the Netherlands, organised a panel discussion and the book launch of ‘Frontex and Human Rights’,…
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Chasing nanoplastics
How dangerous are micro- and nanoplastics? Do they affect the environment? What harm can they do to our bodies? Questions that we can now finally answer because of Fazel Abdolahpur Monikh. Together with his colleagues, he developed a method to detect and quantify nano-sized plastics. Their paper has…
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Saving for discounts by living healthily
A new health programme will reward patients with - or at risk of developing - cardio-vascular diseases for keeping to a healthy lifestyle. A research group including psychologist Andrea Evers has been awarded 2.5 million euros by the Dutch Heart Foundation and the Ministry of Public Health, Welfare…
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Archaeological fieldwork in Central Nicaragua, summer 2014
This coming June and July, excavations will continue at the Aguas Buenas archaeological site.
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Fighting gliobastoma brain tumours with two grants
Few researchers see potential in research on glioblastoma, an incurable brain tumour. Alexander Kros brought together colleagues who are up to the challenge. European research funder ERC recently made 10.6 million euros available, a year earlier NWO provided 3 million euros. ‘In six years, we certainly…
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Stressed brain, stressed heart?
Ilze Bot and Johan Kuiper have published in The Lancet: Study unveils how stress may increase risk of heart disease and stroke. Aso: The National Dutch newspaper 'NRC' has mentioned them in a column
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From lab discovery to a new drug: the Venture Challenge makes it possible
A breakthrough from the PhD research of medical chemist Elmer Maurits may help patients with autoimmune diseases and blood cancer in the future. But bringing a discovery from the lab to the clinic is not so easily done. Thanks to NWO's Venture Challenge, Maurits and his team will receive ten weeks of…
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These Science students excelled and won a KHMW Young Talent Prize
No fewer than seven Leiden FWN students received a Young Talent Award from the Royal Dutch Academy of Sciences on Monday, 29 November. Mark van den Bosch and Karlijn Kruiswijk won a graduation prize, a group of young astronomers won the ET Outreach Award and the other five students each received an…
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Cellular therapy promising treatment for arteriosclerosis
Vanessa Frodermann, a PhD student at the Biopharmaceutical department of the Leiden Academic Centre for Drug Research, has discovered that arteriosclerosis could be inhibited by cellular therapy. Arteriosclerosis is one of the leading causes of the development of cardiovascular disease. Her PhD defence…
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Stress-related prolonged cardiovascular activity: The impact and changeability of stressful cognition without awareness
The research question is that unconscious perseverative cognition (UPC) is responsible for a considerable part of cardiovascular (CV) activity that occurs even in the absence of threats and other stressors that one may encounter in one’s daily life.
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Better vaccines against malaria and tuberculosis
The infectious diseases malaria and tuberculosis are responsible for 2.1 million deaths every year. Leiden researchers are currently testing a new tuberculosis vaccine.
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DNAmarkerpoint
The main purpose of DNAmarkerpoint is to better understand the ecology, evolution and biodiversity through the study of ancient- and modern DNA.
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Mapping Medieval Malaria
This research project studies the distribution and impact of medieval malaria in the Netherlands.
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Fighting in God’s Name
This book underscores the interplay between religion and politics (local and global) in the production, escalation, management, mitigation, and resolution of conflict.
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Discovering and developing drugs
Improving healthcare with our scientific discoveries: that is the goal of pharmaceutical research at Leiden University. And there’s a lot involved in that. Our research starts with the discovery of the effect achieved by a particular substance, and sometimes continues all the way through to the development…
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Animal welfare
We carry a profound responsibility for our research animals and strive to provide them with the best possible quality of life. In our studies, we make every effort to avoid and minimise discomfort for the animals. Below, you can learn more about how this is put into practice.
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Science
The Faculty of Science
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Prediction of human (CNS) target site concentrations in health and disease
Prediction of human (CNS) target site concentrations in health and disease In the vision of Prof. de Lange we will only be able to predict human (central nervous system, CNS) target site concentrations and effects if we perform systematic, condition-dependent, integrative, and strictly quantitative…
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Research lines
Physics and Engineering Approaches to Biomedicine and Pharmacology
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The potters’ perspectives
A vibrant chronological narrative of ceramic manufacturing practices in the valley of Juigalpa, Chontales, Nicaragua (cal 300 CE - present)
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Ephesus
Situated on the west coast of modern Turkey, the site of Ephesus is one of the largest excavations in Turkey and one of the most visited tourist attractions. Only one tenth of the city has been exposed until now although the Austrian Archaeological Institute in Vienna (ÖAI) has been excavating here…
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Tarsus
After the advent of Islam in the 7th century C.E., the strategic geographical position of Tarsus (its proximity to the sea and to the mountain pass leading to inland Anatolia) made this town the de facto capital of the thughur, a historical and geographical term created by Muslim geographers qualifying…
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The domestic implements of the Single Grave Culture: the case of the Noord-Holland province
The use-wear analysis of domestic implements provided new insights of the Single Grave Culture population in the Netherlands.
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Auxin
Mathematical and computational analysis of the dynamics of polar transport of the plant hormone auxin.
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Neutrino telescope KM3NeT receives 12.7 Million Euro NWO grant
KM3NeT is selected as one of the ten top research facilities in NWO’s National Roadmap for Large-scale Research Infrastructure. Leiden physicist Dorothea Samtleben is the deputy program leader of Nikhef’s KM3NeT group.
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ILS/LUF Workshop ‘Search and rescue at sea: The interaction between public and private actors’
On 20 April 2017 Jorrit Rijpma, Eugenio Cusumano, and Melanie Fink organise a Workshop to discuss the legal and policy implications of the surge in privately conducted search and rescue operations in the Central Mediterranean. The Workshop takes place in cooperation between the Law School and the Faculty…
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Sugarcoating the search for a new vaccine
A vaccine based on sugar coats does have the potential to combat a multi-resistant staphylococcus. That is what Jeroen Codée and his colleagues from Utrecht state in Nature. In doing so, they are contradicting the earlier conclusions of German colleagues.