86 search results for “microbiology” in the Public website
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Professor Ben Lugtenberg received ‘The Arima Award for Applied Microbiology’
Emeritus Professor Ben Lugtenberg received ‘The Arima Award for Applied Microbiology’ from the IUMS (International Union of Microbial Societies) for his life-time contributions to this field.
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Kornelia Serwatowska
Science
k.j.serwatowska@cml.leidenuniv.nl | +31 71 527 2727
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Hannah Augustijn
Science
h.e.augustijn@biology.leidenuniv.nl | +31 71 527 4791
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Looking at the big world of microbiology through the smallest lenses
Antoni van Leeuwenhoek, the father of microbiology, died 300 years ago. 2023 has therefore been designated the Antoni van Leeuwenhoek year. The new Unimaginable exhibition in Rijksmuseum Boerhaave is about the amazing world that Van Leeuwenhoek made visible. What was so special about the way he worked?…
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Gilles van Wezel
Science
g.wezel@biology.leidenuniv.nl | +31 71 527 4310
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Anticancer compounds from actinomycetes
How can we find novel natural products from Actinomycetes that act as growth modulators on mammalian cells? Can we harvest and develop the potential of these novel compounds for industrial and medical biotechnology?
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Plant-microbe interactions
Which microorganisms live near and inside plant roots? How do they contribute to plant health? Can microorganisms be employed in plant protection?
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Han de Winde
Science
j.h.de.winde@science.leidenuniv.nl | +31 71 527 1036
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Horizontal gene transfer and spreading of biosynthetic gene clusters and antimicrobial resistance
Biosynthetic gene clusters (BGCs) for natural products are widespread in microbial genomes, and they are rapidly exchanged. This research assesses the factors that control the spread of BGCs and resistance genes in nature. This includes risk assessment for the spread of engineered DNA in nature.
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Harnessing the soil microbiome for improved stress tolerance in crop plants
Which compounds and microorganisms that live near and inside plant roots are beneficial? Can we use this knowledge to improve the health and growth of crop plants?
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New STW-grant to redirect the plant micro biome: “Back to the Roots”
Professors Jos Raaijmakers (NIOO) and Gilles Van Wezel (IBL) received an STW Perspectief- grant of €3 million from the Dutch Technology Foundation and several supporting companies.
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Marjolein Crooijmans
Science
m.e.crooijmans@biology.leidenuniv.nl | +31 71 527 5075
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Unwiring beneficial functions and regulatory networks in the plant endosphere
How do plants lure microscopically small 'support teams' into their roots for protection against diseases? And what functions are activated in the microbes and the plants?
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Host-Microbe Interactions in Microbial Sciences
Microbial Sciences' contribution to the Host-Microbe Interactions research theme is to investigate how beneficial or disease-causing microbes associate and interact with their host.
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Xinya Pan
Science
x.pan@biology.leidenuniv.nl | +31 71 527 4791
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Anna Roseboom
Science
j.m.roseboom@biology.leidenuniv.nl | +31 71 527 4395
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Less is more: reduced mycelial heterogeneity for improved production of enzymes and antibiotics
How can cell wall engineering approaches be used to improve streptomycetes for industry to make new antibiotics?
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Gitlab
GitLab is a single application for the entire software development lifecycle. We use the Leiden University gitlab services
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MicroGRICE: Greenhouse Gas Reduction in RICE: MICRO-biome climate smart applications
Can we use indigenous microbial rice communities to reduce methane production in agricultural settings?
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Molecular Genetics and Biotechnology (MSc)
In the master’s specialisation Molecular Genetics and Biotechnology at Leiden University students are trained by experts in the areas of molecular biology, microbiology, plant genetics, cellular imaging, animal disease models, and various –omics technologies and the corresponding bioinformatics.
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Evolution & Biodiversity in Microbial Sciences
Microbial Sciences' contribution to the Evolution & Biodiversity research theme focuses on understanding how bacteria sense and respond to their environment, and how bacterial diversity and evolution is influenced by cooperative and antagonistic interactions taking place between microbes.
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The archaellum: a rotating type IV pilus
Now online in Molecular Microbiology our studies on the motility of Sulfolobus acidocaldarius and its unique swimming organelle, the archaellum.
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Advisory Board
The Advisory Board of the IBL consists of five eminent scientists with specialist expertise in complementary disciplines. They all have prominent positions for the field of Biology in the Netherlands outside our own institute.
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Soil bacteria can produce a wealth of new antibiotics
Soil bacteria can produce a wealth of antibiotics that are new to us, claims Gilles van Wezel, Professor of Molecular Biotechnology at the Institute of Biology Leiden. His research group has developed a method that can rapidly identify and produce these unknown compounds.
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From stress to success: how actinobacteria exploit life without a cell wall
The central question of this Vici proposal is to investigate if, and how actinobacteria exploit life without a cell wall.
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Our approach
Our group operates at the cross-roads of different disciplines: molecular and cellular microbiology, biochemistry, structural biology and biophysics. The group harbors expertise in a multitude of molecular and cellular approaches including:
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Véronique Ongenae
Science
v.m.a.ongenae@biology.leidenuniv.nl | +31 71 527 5075
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Dennis Claessen
Science
d.claessen@biology.leidenuniv.nl | +31 71 527 5052
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Anthropogenic effects on links between macro-invertebrate diversity and ecosystem functioning
How are links between macro-invertebrate diversity and ecosystem functioning influenced by anthropogenic pressures?
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Lipid mediated colloidal interactions
The lipid membrane is a basic structural component of all living cells. Embedded in this nanometer-thin barrier, membrane proteins shape the membrane and at the same time respond to the shape of the membrane.
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Expertise
The CMCB brings together a diverse range of unique expertise in microbial cell biology. Members of the CMCB investigate both model and non-model organisms, bacteria and archaea, pathogens and non-pathogens.
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Centre for Microbial Cell Biology
The CMCB brings together microbial cell biology expertise in Leiden. It aims at optimal resonance between the groups and maximal exploitation of the available infrastructure and to develop innovative cross-boundary technology platforms.
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Development of innovative engineered models for viral diseases
A main goal of MSBB research is to address the major bottle-necks in combatting viral diseases: the lack of experimental models that are representative of human pathology and are cost effective and versatile. Viral diseases such as those that cause viral hemorrhagic syndromes or severe acute respiratory…
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Potential interference of fungal endophytes in Vanilla planifolia on vanilla flavor compounds biosynthesis
Natural vanilla flavor is one of the most important in the world. However, the cost of this flavor is expensive. Production of this flavor by alternative methods, could reduce the cost.
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Bioactive Molecules in Microbial Sciences
Microbial Sciences' contribution to the Bioactive Molecules research theme is to discover new bioactive molecules and enzymes and unravel their mechanisms of action, regulatory networks, and the (bio)synthetic pathways required for their production.
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Key publications
Key research articles and book chapters of the Chromatin group.
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PhD student in Plant - Microbe symbiosis
Science, Institute of Biology Leiden (IBL)
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Microbial Induction of Plant Resilience to Drought Stress (MicroRes)
What are the genes and molecular mechanisms involved in bacteria-mediated plant drought tolerance?
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Unfolding the principles of genome folding and dynamics in bacteria
What are the principles of genome folding and dynamics in bacteria?
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Functions of autophagy in the filamentous fungus Aspergillus niger
What are the functions of autophagy in the filamentous fungus Aspergillus niger?
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Bacteria evolve gambling behaviour
In an unpredictable environment bacteria evolve the same strategy as shareholders who try to protect themselves against unpredictable swings in the stock market. Experimental evolution biologist Dr Bertus Beaumont published an article on this discovery on 5 November in the journal Nature.
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Six million boost to search for new antibiotics
Edith Schippers, Minister of Health, will be investing six million euros over the coming four years to boost research on new antibiotics. The programme will be set up by several different parties, including the Leiden Centre for Antimicrobial Research.
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About
The Institute of Biology Leiden (IBL) is an internationally oriented institute for research and education in biology. We are part of the Faculty of Science at Leiden University.
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Cell architecture and pathways for parallel secretion in the filamentous fungus Aspergillus niger
Research aims: Identification of key genes involved in programming the cellular architecture of A. niger & Genetic engineering of A. niger in order to improve its secretory capacities and rheological behavior under industrial fermentation conditions.
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Key publications
Key publications of the Quantitative Pharmacology group
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New Directors of Education IBL
Remko Offringa, Associate Professor in Plant Developmental Genetics, and Associate Professor in Molecular Microbiology Arthur Ram both have been appointed as the new Directors of Education at the IBL. Offringa in the role as Director of Education for the Master program and Ram as Director for the Bachelor…
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LUMC involved in development of novel drugs to treat and prevent SARS-CoV-2 and other coronaviruses
The Department of Medical Microbiology at Leiden University Medical Center (LUMC) is researching antiviral drugs that could treat and prevent SARS-CoV-2 in various projects. One part of the PanCoroNed project is being led by Martijn van Hemert and involves lab tests into the antiviral effect of molecules…
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Which MPs have Leiden roots?
Twenty-two of the 150 newly elected members of the Dutch House of Representatives studied at Leiden University or did their PhD research here. But who are they and which degrees are most popular?
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Cancer pathogenesis and therapy
With cancer, a person’s body cells grow uncontrollably. Putting together a detailed picture of how this comes about makes it possible to develop efficient therapies. Researchers at the Leiden University Medical Centre (LUMC) and Leiden University are working together to gain a better understanding…