69 search results for “bioactive molecules” in the Student website
-
Lina Bayona Maldonado
Science
l.m.bayona.maldonado@biology.leidenuniv.nl | +31 71 527 4791
-
Nicola Thome
Science
n.u.thome@biology.leidenuniv.nl | +31 71 527 4395
-
Annemarie Meijer
Science
a.h.meijer@biology.leidenuniv.nl | +31 71 527 4927
-
Researchers tackle antibiotic-resistant bacteria
When a bacterium becomes more resistant to one antibiotic, it sometimes becomes more sensitive to another. To better understand this interaction, researchers from the Leiden Institute of Biology (IBL) and the Leiden Academic Center for Drug Research (LACDR) under supervision of Daniel Rozen and Coen…
-
Surprising molecule helps detect protoplanets
A team of scientists, including Leiden Astronomer Alice Booth, has discovered silicon monosulfide molecules in the dust disk around a young star. Such molecules indicate planet formation. The team made the discovery using the ALMA telescopes. This method provides an alternative when direct observation…
-
Modified caffeine molecules help medical research move forward
Before researchers can develop targeted drugs, they need to know exactly how a disease works. Biochemist Bert Beerkens created molecules that allow them to find out. He used caffeine as the basis for new molecules that enable research into certain receptor proteins on cells.
-
What do complex molecules tell us about star formation?
How do you progress from an immense gas cloud somewhere in the universe to a star with planets? Research by Astronomy PhD student Martijn van Gelder sheds more light on the earliest phases of this process. He will receive his doctorate on November 24th.
-
Tracking the origin and evolution of molecules in space
How do molecules originate and evolve in space? And how does that ultimately determine the chemical composition of planets and their atmospheres? The Dutch Astrochemistry Network (DANIII) receives 1.6 million euros from NWO to find out. A large group of Leiden astronomers and chemists is contributing:…
-
Michel Orrit
Science
orrit@physics.leidenuniv.nl | +31 71 527 2727
-
Not wrapping but folding: Bacteria also organise their DNA (but they do it a bit differently)
Some bacteria, it turns out, have proteins much like ours that organise the DNA in their cells. They just do it a bit differently. This is revealed by new research from biochemists at the Leiden Institute of Chemistry and the Max Planck Institute for Biology. The discovery helps us better understand…
-
Remus Dame
Science
rtdame@chem.leidenuniv.nl | +31 71 527 5605
-
Dennis Hetterscheid
Science
d.g.h.hetterscheid@chem.leidenuniv.nl | +31 71 527 4545
-
Geert-Jan Kroes
Science
g.j.kroes@chem.leidenuniv.nl | +31 71 527 4396
-
Laura Heitman
Science
l.h.heitman@lacdr.leidenuniv.nl | +31 71 527 4558
-
Marcel Schaaf
Science
m.j.m.schaaf@biology.leidenuniv.nl | +31 71 527 4975
-
Amin Moradi
Science
moradi@physics.leidenuniv.nl | +31 71 527 5676
-
Fatema Zahra Rashid
Science
f.z.m.rashid@lic.leidenuniv.nl | +31 71 527 1037
-
Planet-forming discs around young low-mass star differs fundamentally from one around sun-like star
Using the James Webb Space Telescope, an international team of researchers, including Leiden Professor of Molecular Astrophysics Ewine van Dishoeck, has discovered a palette of hydrocarbons in a planet-forming disc around a young, low-mass star. The results confirm that discs around very lightweight…
-
Alireza Mashaghi Tabari
Science
a.mashaghi.tabari@lacdr.leidenuniv.nl | +31 71 527 4425
-
Open Science debate - STIBNITE: developing the next generation organic semiconductors
Conference
-
Hunting for life’s building blocks at minus 250 degrees Celsius
James Webb life’s building blocks
-
With this algorithm, new medicines can be found more quickly
Did he dare take a gamble with his PhD research? Jeroen Methorst didn’t have to think long about it. It could fail or turn out very well. The latter is the case. Methorst developed a computer system that helps researchers find the protein they need. ‘Our whole group is now using this program.’ Methorst…
-
Making the invisible visible with ‘click chemistry’
Sander van Kasteren (Professor of Molecular Immunology) makes the invisible visible. He will explain more in his inaugural lecture.
-
Madouc Bergers made her own enzyme inhibitors for her bachelor’s thesis
For her bachelor’s thesis, Molecular Science and Technology student Madouc Bergers synthesized her own molecule that can inhibit the breakdown of sugars. Although most students do not even manage to make one building block, Madouc made three. Partly because of this, she has been nominated for the Science…
-
Flu stops when you block the enzyme that cleaves off virus particles
A flu virus could cause a pandemic. And then we would be poorly armed because flu viruses are starting to become resistant to flu medications like Tamiflu. Chemist Merijn Vriends successfully worked on an improved version of such medications. He will be awarded his doctorate on September 12th.
-
In memoriam Harold V.J. Linnartz 1965 – 2023: Unlocking the Chemistry of the Heavens
With great sadness we share the news that Prof. Harold Linnartz passed away suddenly and unexpectedly on Sunday 31 December 2023. We are all in shock, and our thoughts are with his wife and children, other family, and friends. Harold was at the heart of our institute, as a researcher, as a supervisor,…
-
Artificial intelligence as the co-pilot for drug discovery
There are more molecules that could conceivably be candidate drugs than there are stars in the universe. How can we ever efficiently identify those molecules? Professor of AI and Medicinal Chemistry, Gerard van Westen: ‘I’m going to use artificial intelligence as the co-pilot to make an automated search.’…
-
Antibiotic resistance: an economic problem universities could help to solve
Antibiotic resistance is an economic problem. Pharmaceutical companies cannot earn much from antibiotic research, so they do not invest in it. This makes it important that universities do so, says Ned Buijs.
-
Webb detects icy ingredients for making potential habitable worlds
An international team of astronomers, led by Will Rocha of Leiden Observatory, using the NASA/ESA/CSA James Webb Space Telescope have discovered that the key ingredients for making potentially habitable worlds are present in early-stage protostars, where planets have not yet formed.
-
Status update in the evolutionary race between humans and resistant bacteria: two steps forward for us
A patent for what may be a potent, new antibiotic. And: a clear overview of promising approaches to overcome a crucial resistance tactic employed by bacteria. In the span of one week, two researchers from Leiden are receiving their PhDs, each of them on an important step in the battle against bacteria…
-
Astronomers spot benzene in planet-forming disk around star for first time
An international team of astronomers including Leiden professor Ewine van Dishoeck has observed the benzene molecule (C6H6) in a planet-forming disk around a young star for the first time. The observations tell us more about the forming of planets in this disc, like our own Earth. The scientists publish…
-
Improving nature’s antibiotic
'What nature made isn’t necessarily an optimized medicine to use in the human body,’ says Professor of Biological Chemistry Nathaniel Martin. That’s why a group of Leiden researchers is making a chemistry-based improved version of the frequently used antibiotic vancomycin. They received an NWO NACTAR…
-
‘Ultimately, the goal is to develop antibiotics for tuberculosis with a lower risk of resistance’
Tuberculosis stands as one of the most lethal infectious diseases worldwide. A significant challenge in combatting tuberculosis lies in the emergence of antibiotic resistance triggered by genetic alterations, commonly known as mutations. These mutations can diminish the responsiveness to antibiotics,…
-
Rubicon grant for Remko Fermin: superconducting diodes for energy-efficient data centres
Physicist Remko Fermin from Leiden University was awarded a Rubicon grant from NWO. He will use it to study superconducting diodes that could contribute to reducing the CO2 emission of data centres.
-
What if superbugs were as tall as buildings?
In Sci-Fi comic book Resist NOW!, wondrous adventures will illustrate possibilities to combat antimicrobial resistance. But the comic book will only be produced if enough money is raised to make the project into reality.
-
€10.6 million for innovative toolboxes to tackle brain cancer
Researchers at the Universities of Amsterdam (Uva) and Leiden together with the Netherlands Cancer Institute and Oncode Institute have received a €10,6 million ERC Synergy Grant to develop innovative therapeutic approaches to target glioblastoma. This is a deadly primary brain tumour for which no curing…
-
First detailed picture of ice in planet-forming disk
An international team of astronomers led by Ardjan Sturm of the Observatory has made the first two-dimensional inventory of ice in a planet-forming disk of dust and gas surrounding a young star. The researches, including Melissa McClure, used the James Webb Space Telescope and publish their findings…
-
Fighting gliobastoma brain tumours with two grants
Few researchers see potential in research on glioblastoma, an incurable brain tumour. Alexander Kros brought together colleagues who are up to the challenge. European research funder ERC recently made 10.6 million euros available, a year earlier NWO provided 3 million euros. ‘In six years, we certainly…
-
From discovery to business: 'In the lab, we often don't realise that we are working to help an immense number of patients'
'It gave our team a big boost to hear that our work was valuable,' says medical chemist Elmer Maurits about the moment they won the Venture Challenge. With their company Iprotics, they want to develop a drug that can better treat patients with autoimmune diseases and blood cancers. 25,000 euros of prize…
-
'If you think astronomy is a man's world, then it's your job to make a change'
During her master's thesis, Nashanty Brunken (24) worked in a team with five other women. With this female team, they discovered the largest molecule so far identified in a disc. 'I have learned so much and because we are all women, it is incredibly empowering. It's very cool to see how far we've come…
-
A look behind the scenes at the Leiden Science Family Day
More than 700 visitors got to know the Science Faculty during the Leiden Science Family Day. People of all ages could enjoy fascinating experiments, tours, interesting lectures, spectacular nitrogen shows and various workshops. It was an informative day with many (future) scientists, amazement and,…
-
Royal honour for emeritus professor Ad IJzerman
Ad IJzerman, Emeritus Professor of Pharmacochemistry, was made a Knight of the Order of the Lion of the Netherlands on 26 April. He was presented with the royal honour by Mayor Elbert Roest in the town hall in Bloemendaal.
-
Two ERC Consolidator Grants for Leiden researchers
Research on quantum computers and Islamic charities: two Leiden researchers have received a Consolidator Grant from the European Research Council.
-
How Oncode-PACT is bringing new cancer medicines closer with 325 million in Growth Fund money
How can you ensure that more experimental drugs reach the finish line? At the moment, only one in twenty cancer drugs that are tested on humans makes it to the market. This is an enormous loss for patients and society. With a grant from the National Growth Fund, Oncode-PACT aims to efficiently select…
-
Ewine van Dishoeck goes stargazing
From the birth of the universe to the molecules in a planet's atmosphere. The first five pictures from the James Webb Space Telescope (JWST) show the enormous range in which the space telescope can operate. Ewine van Dishoeck, professor of molecular astrophysics, took a look at the first images Tuesday…
-
Leiden PhD student discovers thin atmosphere on exoplanet TRAPPIST-1 c with JWST
A group of astronomers led by Leiden PhD student Sebastian Zieba has discovered using the James Webb Space Telescope (JWST) that the rocky exoplanet TRAPPIST-1 c has a thin atmosphere. Although the planet is nearly identical to Venus in size and temperature, and was expected to have a thick atmosphere,…
-
Four Vici grants for Leiden University researchers
Four researchers from Leiden University have been awarded prestigious Vici grants the Dutch Research Council (NWO) has announced. The honoured applications are from researchers at the Faculty of Social and Behavioural Sciences, Leiden Observatory, the LUMC and the Faculty of Archaeology.
-
Wood formation further explored by NWO-XL grant
Leiden researchers, Professor Remko Offringa and co-applicants Salma Balazadeh and Frederic Lens received an NWO-XL grant (2.5 million euros). Together with researchers in Wageningen and Groningen, they will study the genetic and environmental drivers of woodiness. From plant to molecule, the groups…
-
And the winner is… Results of the annual physics image competition
Salt crystals, a nano-sized golf stick and molten glass. The LION Image Award competition of 2023 yielded a lot of beautiful images once again. But in the end, only one can be the winner.
-
Reliable research with virtual patients
The right medicine in the right dosage for every patient, that is something medical science aspires. 'Personalised medicine' is the term for that. But it does require a lot of research with patient data and that can be hard to get due to privacy legislation. Researchers Laura Zwep and Coen van Hasselt…