1,091 search results for “acute en chronische stress” in the Public website
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Cholesterol metabolism and hematopoiesis interaction in atherothrombosis
Cardiovascular disease is the leading cause of death worldwide.
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‘I always thought I was immune to stress, but now I’m not so sure’
Lecturers had a week to move their courses online. An enormous challenge because remote teaching definitely wasn’t commonplace at Leiden University. Suzan Verberne, a lecturer and researcher at LIACS, shares her experiences. ‘I tried to do too much in my first week working from home.’
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Risk stratification of outpatient management in acute venous thromboembolism
PhD defence
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Therapeutic intervention to enhance atherosclerotic plaque stability
Proteases degrade matrix molecules in the atherosclerotic plaque, thereby reducing atherosclerotic plaque stability. Mast cells, that contain proteases such as tryptase and chymase, have been identified at the site of rupture in specimens of human coronary arteries and their number in the plaque was…
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Conferencia de la Prof.dr. Sayak Valencia en el X Congreso Internacional de la AHBx
El viernes 3 de noviembre a las 11.15 tendremos el gusto y honor de escuchar a la Prof.dr. Sayak Valencia en el marco del X Congreso Internacional de la AHBx. Prof.dr. Sayak Valencia (Tijuana, Mexico, 1980) impartirá la segunda conferencia plenaria del X Congreso Internacional de la AHBx bajo el título:…
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Research projects
The research of the Van Eck Group focusses on 3 interconnected research lines: 1) Identification and therapeutic targeting of key pathways/regulators in macrophages essential for prevention of atherosclerotic lesion development or stimulation of regression of existing lesions, 2) Atherosclerosis as…
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2024
Elk jaar organiseert het LIBC in samenwerking met de gemeente Leiden een Publieksdag over hersenonderzoek.
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Stressed-out Stress Systems
PhD defence
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War in Ukraine
Information about the situation in Ukraine
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Een dag vol (nep)skeletten en mammoettanden
De Faculteit Archeologie bestaat dit jaar 25 jaar. Ter ere van dit jubileum opende de faculteit op 1 maart zijn deuren voor het brede publiek.
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The endocannabinoid system in zebrafish larvae
In this thesis, we have studied the potential of the zebrafish larval model in studying the ECS, as a complementary model to the existing rodent models.
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Activity-based protein profiling of diacylglycerol lipases
Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt
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Ecology, Migration and Tolerance: Limits to Cooperation
Many of the most acute problems we face today are global: they transcend national boundaries, they put the future of society and even humanity at peril, and they can only be addressed through international cooperation. However, what can international cooperation deliver? Find out in the minor Ecology,…
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Swimming Bass under Pounding Bass: fish response to sound exposure
Promotor: C.J. ten Cate, Co-promotor: H.W. Slabbekoorn
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Phenotypic engineering of photosynthesis related traits in Arabidopsis thaliana using genome interrogation
Promotor: P.J.J. Hooykaas, Co-Promotor: E.J. van der Zaal
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Vijver en Barmentlo in radio show Vroege Vogels about Living Lab results
Water fleas and damselflies are much more sensitive to crop protection products in nature than in the lab. These test results from the Living Lab were presented by Henrik Barmentlo and Martina Vijver in Dutch radio show Vroege Vogels.
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Priyanka Chopra
Science
p.chopra@biology.leidenuniv.nl | +31 71 527 1886
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Stephanus Huijbregts
Faculteit der Sociale Wetenschappen
shuijbregts@fsw.leidenuniv.nl | +31 71 527 1723
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Hans Slabbekoorn
Science
h.w.slabbekoorn@biology.leidenuniv.nl | +31 71 527 5049
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Renate Buisman
Faculteit der Sociale Wetenschappen
r.s.m.buisman@fsw.leidenuniv.nl | +31 71 527 3441
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Maximilian König
Faculteit der Sociale Wetenschappen
m.konig@fsw.leidenuniv.nl | +31 71 527 6619
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Marret Noordewier
Faculteit der Sociale Wetenschappen
m.k.noordewier@fsw.leidenuniv.nl | +31 71 527 8852
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Daan Scheepers
Faculteit der Sociale Wetenschappen
scheepersdt@fsw.leidenuniv.nl | +31 71 527 3642
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The team
Meet the people of the Resilience Center
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Multimodality imaging for myocardial injury in acute myocardial infarction and the assessment of valvular heart disease
PhD defence
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Triage of stroke patients in the chain of acute stroke care
PhD defence
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Research
Although there has been an increase in the research into brain function and dysfunction in relation to stress and emotions, there are still many unanswered questions.
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Healthy Society
The theme 'Healthy Society' is one of the focal points of the Faculty of Social and Behavioural Sciences (FSW).
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INFLANET - Training European Experts in Inflammation: from the molecular players to animal models and the bedside
How is inflammation in tuberculosis controlled by interplay between autophagy and inflammasome signalling?
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Chemical genetics strategy to profile kinase target engagement reveals role of FES in neutrophil phagocytosis, Nat. Comm. 2020
Chemical tools to monitor drug-target engagement of endogenously expressed protein kinases are highly desirable for preclinical target validation in drug discovery. Here, we describe a chemical genetics strategy to selectively study target engagement of endogenous kinases.
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B cell modulation in atherosclerosis
Cardiovascular disease is a major global burden and atherosclerosis is the main underlying pathological process.
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Ethnicity, Orthodoxy, and Policy in Medieval China: The Political Philosophy of Wang Tong (584?-617)
This research project focuses on the thoughts of ethnicity and political orthodoxy in Medieval China by investigating Wang Tong’s works.
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3D Image to Characterize and Optimize antibody-mediated antitumor immunity
Bispecific antibodies with one Fab arm binding to effector cells, such as T-cells and NK-cells, while the other Fab arm recognizing a tumor associated antigen (TAA) can be used to redirect these effector cells for tumor specific killing. Using bispecific antibodies to treat hematological cancers is…
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Protein arginine methyltransferases as modulators of lipid metabolism and inflammation and the relevance for atherosclerosis
Acute cardiovascular clinical events such as myocardial infarction and cerebral stroke represent the major cause of death in Western societies. These pathologies are primarily resulting from atherosclerosis, a progressive condition characterized by the accumulation of lipids, immune cells, and fibrous…
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Chemical genetic approaches for target validation
Drug development is a time- and resource-consuming process that starts with the discovery and validation of a (protein) target that contributes to pathogenesis or disease progression.
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The limits of tolerance: before and after Brexit and the German Refugee Crisis
This study investigates how two social and political developments, in the UK and Germany, impacted on the experiences of minorities and the attitudes of majorities vis-à-vis tolerance in those two countries. The results provide a thought-provoking picture of the views of minority and majority groups…
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Chemical tools to modulate endocannabinoid biosynthesis
Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt
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Innovation in tradition
This dissertation explores the history of the language of a manuscript known as Tönnies Fonne's Russian-German Phrasebook (Pskov 1607).
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Bioengineering and biophysics of viral hemorrhagic fever
Viral hemorrhagic fever (VHF) is a group of acute diseases caused by highly infectious viruses including Ebola, Lassa, Dengue viruses. Its high mortality rate poses high risk to public health, however, studies on VHF have been hampered due to the non-availability of proper models and incomplete knowledge…
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De Jongh & Fougère, Specters of Arendt
The threat of totalitarian domination; the rise of bureaucratic expertise; the resurgence of nationalisms and xenophobia; the claims of religion in secular societies; and the importance of robust legal and political institutions: these are among the main issues that mark—or specters that haunt—the 20th…
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Single-cell immune profiling of atherosclerosis: from omics to therapeutics
Acute cardiovascular syndromes, including myocardial infarction or stroke, are the principal cause of death in the Western society. The main underlying pathology of cardiovascular diseases is atherosclerosis, which is caused by the accumulation of lipids and inflammatory cells in the vessel wall, in…
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Phonetic experiments on the word and sentence prosody of Betawi Malay and Toba Batak
In this study Lilie Roosman describes the effects of prominence and boundary marking on the temporal and melodic structures of two regional languages of Indonesia, viz. Toba Batak, a stress language, and her native language Betawi Malay, a non-stress language.
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Members
LIBC Stress & Emotion is a network focusing on science valorisation and outreach, stimulating interdisciplinary exchange of knowledge and expertise on topics related to brain and cognition/Stress and Emotion. Its research members come from a broad and diverse spectrum of specialized academic fields…
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Hybrid art in the former Dutch East Indies: the Iko ‘oeuvre’ as shared cultural heritage
This project involves research into the oeuvre of the Sundanese sculptor Iko, who has worked for the Catholic mission in Java and has carved sculptures for a chapel and church in Ganjuran. The images were designed by the Catholic layman Jos Schmutzer and are characterized by a fusion in style and symbolism…
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Leijten en Arenas Catalán present current research at conference on economic and social rights
On 9 and 10 November, the Institute of International and European Law of the University of Göttingen and the Minerva Center for Human Rights of the Hebrew University of Jerusalem, organized a conference called ‘Unpacking Economic and Social Rights: International and Comparative Dimensions’.
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Functional characterization and unraveling the Gene Regulatory Networks (GRNs) of HD-Zip transcription factor HB40 (and HB22) in Arabidopsis
In this Ph.D. thesis, we characterized two novel upstream regulators of JUB1, HB40, and HB22, in Arabidopsis thaliana. In Chapter 2, we described functions of HB40 in modulating growth and development via the regulation of JUB1 and GA inactivation genes GA2OXs.
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Illuminating N-acylethanolamine biosynthesis with new chemical tools
In this thesis, the discovery and optimization is described of chemical tools to study the N-acylethanolamine (NAE) biosynthetic pathway.
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Why are governments sharing intelligence on the Ukraine war with the public and what are the risks?
In this article, Thomas Maguire, assistant professor at the Institute of Governance and Global Affairs, examines the intelligence of the US, British and Ukrainian governments and NATO partners concerning Russia and its war against Ukraine. This article discusses how and why governments communicate intelligence…
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Inhibitor discovery of phospholipases and N-acyltransferases
In this thesis an activity-based probe was discovered that could visualize the activity of PLAATs. With an optimized gel-based ABPP assay in hand, screening of a compound library led to the discovery of alpha-ketoamides as a hit for PLAAT3.
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Molecular Signatures of the Evolving Immune Response in Mice following a Bordetella pertussis Infection
Worldwide resurgence of pertussis necessitates the need for improvement of pertussis vaccines and vaccination strategies.