566 search results for “drug treatment” in the Staff website
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How a pathogenic bacterium searches for food
Bacteria whirl around in the mouths of most people, forming dental plaques and sometimes causing nasty gum infections. Treponema denticola might be a dangerous pathogen, but not much is known about this bacterium. It was up to Ariane Briegel and her research group to change that.
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Tom van der Wel
Science
t.van.der.wel@lic.leidenuniv.nl | +31 71 527 3527
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Serkan Aslan
Science
s.aslan@lacdr.leidenuniv.nl | +31 71 527 5919
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Erik Danen
Science
e.danen@lacdr.leidenuniv.nl | +31 71 527 4486
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Madouc Bergers made her own enzyme inhibitors for her bachelor’s thesis
For her bachelor’s thesis, Molecular Science and Technology student Madouc Bergers synthesized her own molecule that can inhibit the breakdown of sugars. Although most students do not even manage to make one building block, Madouc made three. Partly because of this, she has been nominated for the Science…
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Three awarded research projects in NWO-XS call
Cryogenic memories, antibiotic treatment for urinary tract infections and recycling plastic sustainably. These are the subjects of the three NWO-XS grants awarded to Leiden Science researchers.
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In conversation with the head of the rodent facility
Before patients can take a pill, scientists often spend years in the lab developing and testing a candidate drug. That often includes experiments with laboratory animals. As head of the rodent facility, Ilze Bot and her colleagues ensure that these experiments are conducted in an ethically responsible…
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Experimental Studies on the Normative Force of Law: The Problem of 'Treatment Resistance'
Lecture
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Data stewards
Do you have questions about data management? Please contact the data stewards:
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New centre of expertise makes placebo research accessible for healthcare and society
Positive expectations about treatment increase the likelihood of success. The new Center for Interdisciplinary Placebo Studies Leiden is therefore promoting research on the placebo effect and offering expertise and training for care providers. At the opening, the founders demonstrated their VR communications…
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Michiel van de Sande delivers inaugural lecture on advancing sarcoma care
On 5 November 2021, Professor Michiel van de Sande of the Department of Orthopedics in the Leiden University Medical Centre (LUMC) delivered his inaugural lecture ‘The Art of Doing and Doing Nothing’. Van de Sande used the opportunity to explore both physical and philosophical aspects of co-decision…
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Combating antibiotic resistance together
Antibiotic resistance is a common problem among patients. The European Project TIPAT trains pharmacologists, microbiologists and immunologists of six universities in interdisciplinary thinking. The ultimate goal is to develop better treatment guidelines to combat resistance. Coen van Hasselt of the…
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Rob van Wijk
Science
r.c.van.wijk@lacdr.leidenuniv.nl | +31 71 527 4505
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Nature Communications paper on therapeutic melanoma inhibition by local micelle-mediated cyclic nucleotide repression
Cancer immunotherapy represents a significant breakthrough in cancer treatment. However, tumors have numerous mechanisms by which they evade destruction by the immune system. It is therefore necessary to decipher and reverse these mechanisms in order to improve immunotherapies.
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Forum Antiquum Lecture Spring 2022: 'Christiani et Ceteri. The Treatment of Christians in the Roman Empire'
Lecture
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Targeting the immune system to inhibit atherosclerosis
A new treatment for atherosclerosis showed promising results in isolated cells but proved to be less effective in initial animal tests. Bachelor student Biopharmaceutical Sciences Willemijn van der Heijden aimed to understand why. She investigated whether the formation of a protein layer around the…
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ERC-grant for Sebastian Pomplun to cure disease by controlling gene expression with synthetic transcription factors
Sebastian Pomplun receives an ERC starting grant of 1.85 million Euros in five years. He wants to develop synthetic transcription factors that can enter cells and activate or deactivate specific genes. For example to disrupt cancer-related processes or to trigger the production of an important missing…
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Peter Rodrigues ‘The boundaries for discrimination have shifted’
The judicial authorities are looking into the possibilities for prosecution for the slogans that were projected on the Erasmus Bridge in Rotterdam on New Year’s Eve. Not an easy task, according to legal experts. When do we consider something to be ‘discrimination’?
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Maartje van der Woude on discrimination at border controls
In its ruling this week, The Hague Court of Appeal made short work of how the Dutch Border Police allow the colour of a person’s skin to be taken into account when selecting people to check. According to Maartje van der Woude, this ruling reaches far beyond the border police. ‘This is a problem for…
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With 30 million dollars, this consortium aims to tackle tuberculosis
Thanks to a clever research method, progress is being made in the quest for better tuberculosis medications. Within an American consortium that received a 30 million dollars grant, Leiden researcher Rob van Wijk plays a significant role. ‘The next breakthrough in tuberculosis research will come much…
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Gene Networks-based Mechanistic Assessment of Drug-induced Organ Toxicity
PhD defence
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signaling and inflammation: metabolomics for better diagnosis and treatment strategy
PhD defence
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Patient derived zebrafish xenograft models for personalized treatment of uveal melanoma
PhD defence
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Peter Rodrigues on discrimination case Giethoorn: 'Incorrect assessment by police'
The Public Prosecutor’s Office Oost-Nederland, the Police in Oost-Nederland and the municipality of Steenwijkerland failed in their handling of a case involving discrimination in Giethoorn. This is the opinion of experts, including Professor Peter Rodrigues, in Dutch investigative journalism programme…
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Farewell symposium Prof. dr. Joke Bouwstra
Valedictory lecture
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Digital accessibility
The digital accessibility expert group focuses on improving the accessibility of the university website, digital learning tools and digital examinations. As a result of the corona crisis many educational activities are now online. The group is therefore working closely with the Centre for Innovation…
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Sibel Bahtiri is one of the new Faces of Science: ‘I want to show how we’re finding alternatives to animal testing’
PhD candidate Sibel Bahtiri is one of the new Faces of Science. In videos and blogs, she will show what life is like as a young researcher.
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Why arteriosclerosis looks like an autoimmune disease
Arteriosclerosis bears great similarities to autoimmune diseases. Researchers from Leiden University show this in a new study they published in the renowned scientific journal Nature Cardiovascular Research. 'This discovery suggests that treatment methods for autoimmune diseases might also be effective…
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Atherosclerosis resembles an autoimmune disease. Marie Depuydt graduated on this topic, with honours
In addition to cholesterol and high blood pressure as risk factors for atherosclerosis, we may need to address our own immune system to prevent a heart attack or stroke. Marie Depuydt revealed which cells exactly reside in the atherosclerotic plaque that narrows an artery. The presence of a diverse…
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With this algorithm, new medicines can be found more quickly
Did he dare take a gamble with his PhD research? Jeroen Methorst didn’t have to think long about it. It could fail or turn out very well. The latter is the case. Methorst developed a computer system that helps researchers find the protein they need. ‘Our whole group is now using this program.’ Methorst…
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LUMC signs international agreement on developing Advanced Therapy Medicinal Products
Skåne University Hospital, Lund University and Leiden University Medical Center will work together to expand their research, teaching and development relating to Advanced Therapy Medicinal Products. That is the essence of a Memorandum of Understanding signed at SciLifeLab near Stockholm on Wednesday…
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Researchers tackle antibiotic-resistant bacteria
When a bacterium becomes more resistant to one antibiotic, it sometimes becomes more sensitive to another. To better understand this interaction, researchers from the Leiden Institute of Biology (IBL) and the Leiden Academic Center for Drug Research (LACDR) under supervision of Daniel Rozen and Coen…
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300 million euros for new international stem cell consortium
The Leiden University Medical Center (LUMC), the Danstem Institute from the University of Copenhagen and the Murdoch Children’s Research Institute in Melbourne have received 300m euros from the Novo Nordisk foundation. The aim of this new international consortium is to bring stem-cell based therapies…
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Reliable research with virtual patients
The right medicine in the right dosage for every patient, that is something medical science aspires. 'Personalised medicine' is the term for that. But it does require a lot of research with patient data and that can be hard to get due to privacy legislation. Researchers Laura Zwep and Coen van Hasselt…
- Framing Late Antique Religion Lecture Series
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Unacceptable behaviour
Leiden University aims to create a safe environment where everyone feels comfortable and no one experiences unacceptable behaviour. Should students experience this nevertheless, there are various resources that you can refer them to.
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Interactive lecture 'Brown Eyes Blue Eyes'
Diversity
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Rubicon grant for four Leiden researchers
Four promising young researchers from Leiden University have received a Rubicon grant from the Dutch Research Council (NWO). This grant will enable them to gain valuable research experience at top universities abroad.
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ERC grant to further investigate next-generation antibiotics with reduced toxicity
The European Research Council (ERC) has awarded Nathaniel Martin a Proof of Concept (PoC) grant. With it, his group aims to make a dangerous but potent antibiotic less toxic. He receives €150.000.
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European grant to research colonial medical experiments: 'Should we keep using this data?'
When we think of unethical medical experiments, we tend to think first of Nazi Germany. What is less well known is that experiments were also carried out in colonised areas without the explicit consent of the test subject. University lecturer Fenneke Sysling has received a European grant to research…
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BrAInpower exhibition: tremendous and troubling uses of AI in our daily lives
Care robots, medical treatments, deepfakes and self-driving cars all with the aid of artificial intelligence (AI). The BrAInpower exhibition at Rijksmuseum Boerhaave shows spectacular applications of AI and explains how it can make such huge leaps. Bas Haring, Professor of Public Understanding of Science,…
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‘I am curious and full of passion for understanding molecular chemistry’
Since May, Assistant professor BioTherapeutics Lu Su works in our faculty. Although she is still young, she already worked in many different fields and co-operated on two publications in big scientific journals. How did she become so successful and what motivates her to keep researching the possibilities…
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Study associations sign covenant: limit your alcohol consumption and look after each other
Opting more often for mocktails or soft drinks rather than beer or wine, talking to others about their drinking and pointing out the ban on drugs. Leiden University’s new covenant on alcohol and drugs for study associations encourages providing more alcohol-free alternatives.
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Scouring the brain for causes of psychiatric illnesses
What happens in the brains of people with psychiatric illnesses? With a €23.23 million gravity grant, scientists from different fields will search for biological causes over the next decade. ‘By joining forces, we hope to improve diagnosis and treatment for patients with these diseases.’
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ICT-contact persons
For each university unit, the ICT Shared Service Centre (ISSC) has an appointed ICT contact person responsible for applying for ICT facilities for research, teaching and operational management.
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Health insurance
If you wish, you can take part in the collective health insurance scheme offered by Leiden University and Zorg en Zekerheid. This scheme offers a collective discount, for you and your family.
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Unacceptable behaviour
The workplace should be completely free from unacceptable behaviour, such as bullying, sexual harassment, intimidation, discrimination and violence. If you experience or witness unacceptable behaviour, it can be difficult to talk about it. Yet it’s very important that you report it to one of the confidential…
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Leiden Healthy University
Leiden University is committed to making your work safe, healthy and enjoyable and joined the Healthy Universities international network in 2018.
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PhD candidates
Leiden University strives to accommodate young talent, which is why it does its best to create an inspiring environment for PhD candidates. With the University Training Programme for PhDs, we offer a degree programme that is both complete and challenging.
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Rethinking antibiotic therapy of urinary tract infections
Suruchi Nepal, postdoc in the group of Coen van Hasselt at LACDR, was awarded an NWO XS project which aims to study the response to antibiotic treatment during a urinary tract infection (UTI). This knowledge will be used to determine how treatments of UTIs with antibiotics can be further improved.