1,040 search results for “global gene regulation” in the Public website
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Leiden University modifies BSA regulation for the first year and ends experiment with second year
Leiden University is ending the experiment with the Binding Study Advice in the second year of the bachelor's programme (BSA 2) with immediate effect. Under the terms of BSA 2, students were required to obtain 90 credits within two years, including their first-year diploma.
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ADAPTED
The ADAPTED (Alzheimer's Disease Apolipoprotein Pathology for Treatment Elucidation and Development) project is a major new initiative to investigate an area of Alzheimer's Disease (AD) research which has previously received little attention. The project aims to improve understanding of the function…
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Molecular engineering of plant development using Agrobacterium-mediated protein translocation
Supervisor: P.J.J. Hooykaas Co-Supervisor: R. Offringa
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Evaluation of the zebrafish embryo as an alternative model for hepatotoxicity testing
Promotor: Prof.dr. B. van de Water, Co-promotores: L.T.M. van der Ven, A.S. Kienhuis
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Simcha Jong Kon Chin
Science
s.jong@liacs.leidenuniv.nl | +31 71 527 7201
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Crystal Ennis
Faculty of Humanities
c.a.ennis@hum.leidenuniv.nl | +31 71 527 5635
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T-DNA integration and DNA repair of DSBs in plants
Identification and characterization of components of DNA repair pathways and their role in Agrobacterium T-DNA integration and repair of CRISPR/Cas induced DSBs.
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Workshop: Interdisciplinary Research Design for Global Studies
What does it mean to do “global research”? Global studies is an emerging field that focuses on transboundary, international, and global processes and systems, such as climate change, global social media, and globalization. These issues call for researchers to think beyond conventional state actors or…
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Autism and higher education
How can we improve quality of life and study success in young, high-functioning adults with autism?
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Sheltering 10 billion people in a warming and resource-scarce world: challenges and opportunities
Sheltering is an immediate human need and determines well-being andhealth.
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Half minor Global Health a great success!
The pandemic has challenged us to revisit the way we structure education and how to reach out to students remotely. It almost seems fitting that a course devoted to a topic so closely related to the context of the corona crisis, that of global health, would explore the possibilities of making the course…
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Role of leukocytes in metastasis formation in a zebrafish
How do macrophages and neutrophils contribute to metastatic onset?
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Hybrid zone dynamics in amphibians
Hybrid zones occur where two species meet and produce offspring (hybrids). Typically, hybrids show a considerable reduction in fitness. In this thesis two hybrid zones are treated.
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Lunch Seminar: Transformations in Global Climate Finance
On 8 April, Michael Sampson and Shiming Yang, from the new GTGC Seed Grant project 'Transformations in Global Climate Finance' presented on their research set-up and engaged in a discussion with the audience.
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Functions of leptin in tuberculosis and diabetes: multi-omics studies across species
In this thesis, I study 1) metabolic alterations in tuberculosis related to wasting syndrome in human patients as well as in rodent and fish animal models. 2) effects of the mutation of the leptin gene on cachexia and diabetes in rodent and zebrafish animal models.
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2011 Leiden Centre for Global Heritage
A Centre for Global Heritage will be set up at Leiden University, that integrates the unique global breadth and quality of academic expertise at the University and the Leiden Museums with the global infrastructure of practical consultancy expertise built up over the past years by the Centre for International…
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Distinctive user groups
What legislative and regulatory questions arise when children, adolescents or elderly people use the Internet?
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Chromatin organization & dynamics (Dr. Remus Dame)
Throughout all domains of life, from bacteria and archaea to eukaryotes, genomes adopt well-organized three-dimensional structures that can change in space and time to accommodate preferred transcriptional programs for environmental adaptation, the maintenance of cellular identity and differentiation…
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GTGC Global Justice and Human Rights Seminar
On 28 October 2021, Matthew Hoye presented his paper during a seminar organized by the GTGC Global Justice and Human Rights group. His paper was about the Remittances and Global Justice: Paradoxes and Potentials.
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Future Directions in Global Legitimacy Research
Jan Aart Scholte was lead organizer of a conference on ‘Future Directions in Global Legitimacy Research’, held in Stockholm on 21-22 June 2022. The gathering assembled 50 leading scholars on this subject to reflect on future research concerning the sources, processes, and consequences of legitimacy…
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Another global environmental conference is far more successful than the UN Climate Conference
In Montreal, the 34th Meeting of Parties on the Montreal Protocol (MOP), dealing with ozone layer damage, just ended. This protocol is ratified by all countries in the world and is very successful. Shiming Yang, a university lecturer and member of the Leiden University Global Transformations and Government…
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Chemical genetic approaches for target validation
Drug development is a time- and resource-consuming process that starts with the discovery and validation of a (protein) target that contributes to pathogenesis or disease progression.
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Follow the Governance and Global Affairs Blog
Stay in touch with the recent developments at the faculty!
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Science for Society
By carrying out fundamental research and providing excellent education, universities become a breeding ground for innovation and entrepreneurship.
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Paul Hooykaas
Science
p.j.j.hooykaas@biology.leidenuniv.nl | +31 71 527 4933
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Policy brief on 'Deepening G20-UN System Cooperation to Foster Socio-Economic Recovery from the Pandemic and Reduce Inequality Worldwide'
This Think20 (T20) policy brief recommends the introduction of a
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GTGC Global Justice and Human Rights Seminar
On 25 November 2021, Jelena Belic presented her paper during a seminar organized by the GTGC Global Justice and Human Rights group. Her paper was about the Right to Withdraw from International Treaties: A Normative Analysis.
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GTGC Global Justice and Human Rights Seminar
On Thursday 2 June 2022, Olivia Serrano, a guest researcher in the GTGC programme, gave a presentation to the GTGC Global Justice and Human Rights stream. Olivia's presentation was about the Role of Independent Expert Committees in the Interpretation of Human Rights Treaties: the Right to Health as…
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Alan Sears
Faculteit Rechtsgeleerdheid
a.m.sears@law.leidenuniv.nl | +31 71 527 8154
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Simona Demková discusses the EU’s human-centred approach to regulating artificial intelligence
On 27 and 28 April, Simona Demková participated as a panelist at the conference 'A
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Trying to fight global warming with philosophy
In her inaugural lecture Susanna Linberg will ask how philosophy should respond to global warming.
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Ben Van Rompuy on EU competition law and the transnational private regulation of sport
At two recent events, Ben Van Rompuy, Assistant Professor of competition law at the Europa Institute in Leiden, discussed current developments in the application of EU competition rules to regulatory aspects of sport.
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Kick off Honours Programme Tackling Global Challenges
During the honours programme’s start of the year event of September the 15th, Pierre van Eijl and Albert Pilot were invited to talk about their research on talent development in honours programmes and the honours laboratory for 21st century skills. The honours programme with a new name is ‘Tackling…
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Agression and emotions
Cultural and individual differences
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Dr. Amy Strecker receives Global Interactions BREED Grant
Dr Amy Strecker (Heritage Dept., Faculty of Archaeology) has recently been awarded a LGI BREED grant to develop her project on property and spatial justice in international law. Building on her previous research into landscape protection from cultural heritage, environmental and human rights perspectives…
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Rave reviews of anniversary exhibition 'Global Imaginations'
The Dutch press has given the anniversary exhibition in the Leiden Meelfabriek some rave reviews: ‘Global Imaginations is amusing and confrontational.’ The exhibition celebrates the 440th anniversary of Leiden University and can be seen until 5 October.
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Leiden involved in global science communication study
Launched in early March, GlobalSCAPE is an EU-funded project seeking to understand the current state of science communication globally, especially in non-western countries. Through the Department of Science Communication & Society, Leiden University is one of the main partners of the project, which…
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Personalized drug repositioning using gene expression
PhD defence
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Summer School Global and European Labour Law
This summer the department of Labour Law at Leiden University will start a new tradition of an annual summer school addressing current issues in labour law from an international, transnational and European point of view. With a mixture of lectures, seminars and a field trip, topics will be explored…
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Leiden University seventh in global sustainability ranking
Leiden University has taken seventh place in the UI Green Metric, a global sustainability ranking for universities. Almost 1,000 universities from all over the world participate in the ranking.
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Research
At the division of Biopharmaceutics, we aim to develop and test new therapeutic approaches to limit or even prevent the development of atherosclerosis in order to reduce the number of acute cardiovascular syndromes such as myocardial infarction or stroke.
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ZF-HEALTH - Zebrafish Regulomics for Human Health
How can zebrafish research help understanding human diseases?
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Understanding plant transgenesis
How is Pol θ responsible for T-DNA integration, and how do other DNA double-strand break repair pathways interact with Pol θ? How may we manipulate T-DNA integration to stimulate error-free integration at a predetermined genomic site?
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Chitin in the fungal cell wall: towards valorization of spent biomass of Aspergillus niger
Aspergillus niger is an important industrial producer of organic acids and enzymes producing large amounts of spent fungal biomass.
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In Pursuit of Next-Generation Lipopeptide Antibiotics
Can new variants of daptomycin and the polymyxins be found?
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Functional analysis of agrobacterium tumefaciens virulence protein VirD5
Supervisor: P.J.J. Hooykaas
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Chemical genetics strategy to profile kinase target engagement reveals role of FES in neutrophil phagocytosis, Nat. Comm. 2020
Chemical tools to monitor drug-target engagement of endogenously expressed protein kinases are highly desirable for preclinical target validation in drug discovery. Here, we describe a chemical genetics strategy to selectively study target engagement of endogenous kinases.
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Resistance to PARP inhibition by DNA damage response alterations in BRCA1/2-deficient tumors
Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.
- Leiden Institute of Chemistry
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Unravelling cell fate decisions through single cell methods and mathematical models
Despite being the object of intense study, embryonic development has been difficult to model due to a number of reasons. First, complex tissues can be comprised of many cell types, of which we probably only know a subset.