2,851 search results for “disease prevention” in the Public website
-
Learn to Dare!
The ‘Leer te Durven!’ program (Learn to Dare) is a preventive training program for children with mild anxiety symptoms (Simon & Bögels, 2014). The program has been developed for children between the ages of 8 and 12 who feel or behave anxiously, avoid situations, are afraid of doing things wrong, appear…
-
Research lines
Current research at the Skin Barrier and Vaccination group.
-
Drugs for our immune system in the right place at the right time
Immunologist Leender Trouw specialises in the complement system, which is part of the immune system. In some diseases drugs help activate or inhibit this system. This is best done ‘in the right place at the right time’ − the title of his inaugural lecture.
-
What makes us ill?
Genes predict whether you have a propensity for an illness but environmental factors often have the last word: nutrition, air pollution, lifestyle, stress. The exposome as both culprit and chance. Large-scale research is being carried out into this at Leiden. Thomas Hankemeier, Professor of Analytical…
-
Better vaccines against malaria and tuberculosis
The infectious diseases malaria and tuberculosis are responsible for 2.1 million deaths every year. Leiden researchers are currently testing a new tuberculosis vaccine.
-
Vascular and Regenerative Medicine
Methods of treatment for chronic illnesses are limited. Doctors and researchers at Leiden University Medical Center (LUMC) and Leiden University are working on new therapies as an alternative for organ transplants. The goal is to cure the illnesses by restoring organs to their original function. Stem…
-
Global Public Health (BSc Major of Liberal Arts and Sciences: Global Challenges)
Although the world has made tremendous progress in health, education, sanitation and hygiene, global public health challenges still exist. Disparities in health exist between and within nations as evidenced by inequalities in disease burden, mortality, nutrition and environmental well-being. How does…
-
Osteoarchaeologist Maia Casna receives the NVFA Incentive Prize: ‘I try to push osteology into the public eye as much as I can’
PhD candidate Maia Casna received an Incentive Prize from the Dutch Association for Physical Anthropology (NVFA). She was rewarded this honor for her innovative research into respiratory diseases and her talent for presenting her results to both academic and general audiences. ‘It feels really nice…
-
CD11b+Gr-1+ myeloid-derived suppressor cells reduce atherosclerotic lesion development in LDLr deficient mi
Publication by: Amanda Foks, Gijs van Puijvelde, Jolien Wolbert, Mara Kröner, Vanessa Frodermann, Thomas van der Heijden, Peter van Santbrink, Louis Boon, Ilze Bot and Johan Kuiper. Cardiovascular Research. 2016;111(3):252-261.
-
‘We couldn't really celebrate our vaccine being approved, but we were over the moon’
On 11 March, pharmaceutical company Janssen received approval to launch its corona vaccine on the European market. This made Janssen the fourth company to be given the green light by the European Medicines Agency. As Lead of the Janssen Campus in the Netherlands, Biology alumnus Bart van Zijll Langhout…
-
Strategies to Investigate Lipoprotein Metabolism and Combat Cardiometabolic Disease
PhD defence
-
Versatile SNP genotyping
The SNP genotyping line offers flexible genotyping for small and large projects at affordable price and high quality. The use as SNPs as molecular markers is very versatile and can be used for a wide variety of scientific questions ranging from paternity analysis, conservatuion genetis towards QTL…
-
Growth and development of actinomycetes
We aim to provide new insights relating to the spectacular multi-cellular life cycle of streptomycetes and other actinobacteria.
-
Development and evaluation of evidence based self-help and online programs for people with a somatic stressor and depressive symptoms
What is the effectiveness of (booklet or online) self-help programmes for people with somatic stressors and depressive symptoms? What works best for whom? How to improve motivation and adherence?
- Contact
-
Imaging and Bioinformatics
On the basis of the characteristic aspects of a picture, certain computers can tell us what the picture is showing. They can learn this in the same way that young children are able to learn to recognize images. Further improving these techniques opens the way to a whole range of new applications. Biology…
-
Skin Barrier and Vaccination
The Skin Barrier and Vaccination group is led by Prof. Joke Bouwstra. One of the key functions of the skin is its barrier function, which is located in the uppermost layer of the skin, the stratum corneum. The stratum corneum consists of enucleated dead cells (corneocytes) embedded in a lipid matrix.…
-
Education
The Faculty of Archaeology at Leiden University offers education in Human Osteoarchaeology. We offer a second-year Bachelor course in Human Osteoarchaeology and an extensive one-year track in the Master’s in Archaeological Science specialisation, resulting in a Master of Science degree after complet…
-
Serge Rombouts: 'AI is learning from brain scans and helping find a diagnosis'
Serge Rombouts is a physicist whose PhD thesis was about functional MRI (fMRI). This visualises activity in regions of the brain. The appealing images of glowing brain regions that emerge from the computer are the result of calculations. According to Rombouts, this isn’t proper artificial intelligence.…
-
Research
The chemical industry must continue to innovate for a more sustainable, healthier society. The reseachers from the Leiden Institute of Chemistry (LIC) contribute by applying their knowledge to themes such as sustainability, energy and health.
-
Partners
Our research programme collaborates with all kinds of partners to achieve our goal: bringing scientific discoveries to the clinic as soon as possible.
-
Unwiring beneficial functions and regulatory networks in the plant endosphere
How do plants lure microscopically small 'support teams' into their roots for protection against diseases? And what functions are activated in the microbes and the plants?
-
Quantitative Systems Pharmacology
This research area is focused on the development and application of novel concepts and models in the emerging area of quantitative systems pharmacology (QSP).
-
Kinetic profiling of positive allosteric modulators of the mGlu2 receptor
Supervisor: Maarten Doornbos
-
Systems Biomedicine and Pharmacology (MSc)
The two-years master’s specialisation System Biomedicine and Pharmacology at Leiden university focuses on predicting drug response with computational modelling, developing individualised therapies, and developing innovative analytical tools for personalised health strategies.
-
NWO grant gives way to more sustainable production of antibiotics
The opportunity to explore a new, exciting research topic. That is how Lennart Schada von Borzyskowski describes his successful application for the NWO XS grant. It comprises 50,000 euros, which the researcher from the Institute of Biology Leiden (IBL) will spend on investigating a more sustainable…
-
Discovery Leiden nominated for KIJK: Best Tech-idea of 2021
Using artificial intelligence to find new antibiotics. With that, researchers from Leiden University are nominated by magazine KIJK for the Best Tech-idea of 2021. From September 14 onwards people can vote to crown one of the nominees as the winner.
-
Cleaning up tuberculosis and salmonella infections
The cellular recycling system in zebrafish is capable of eating harmful bacteria and thus resist infections such as tuberculosis and salmonellosis. That is written by Leiden biologists from the group of Annemarie Meijer. Stimulating this form of defence could be used in new treatment methods against…
-
Ultrasensitive in situ visualization of active glucocerebrosidase molecules
Deficiency of glucocerebrosidase (GBA) underlies Gaucher disease, a common lysosomal storage disorder. Carriership for Gaucher disease has recently been identified as major risk for parkinsonism. Presently, no method exists to visualize active GBA molecules in situ. We here report the design, synthesis…
-
Personalized Medicine
Assessing and implementing new diagnostics strategies for stratifying patients
-
B cell modulation in atherosclerosis
Cardiovascular disease is a major global burden and atherosclerosis is the main underlying pathological process.
-
NACTAR: The lugdunomycins: a new class of polyketide antibiotics with unique chemical scaffold
Aim of the proposal is to develop lugdunomycin into a drug candidate able to treat infectious diseases caused by multi-drug resistant pathogens.
-
Fluorescence Polarization Activity-Based Protein Profiling on Retaining Glycosidases
Glycosidases are important enzymes in the turnover of polysaccharides and glycoconjugates, and are involved in a range of human pathologies including genetic disorders such as Gaucher and Pompe disease, but also in various cancers.
-
European Lead Factory
The European Lead Factory has been created with the ultimate goal to develop lead drug candidates to address neglected diseases including bacterial infections, psychiatric disorders and oncology.
-
Strategy
The division of BioTherapeutics consists of the former divisions Biopharmaceutics and Drug Delivery Technology.
-
Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity, Nat. Commun., 2017
The cannabinoid CB2 receptor (CB2R) represents a promising therapeutic target for various forms of tissue injury and inflammatory diseases. Although numerous compounds have been developed and widely used to target CB2R, their selectivity, molecular mode of action and pharmacokinetic properties have…
-
Translational pharmacokinetics-pharmacodynamics in zebrafish: integration of experimental and computational methods
The zebrafish is a promising vertebrate model organism in early drug discovery and development.
-
Involvement of host and bacterial factors in Agrobacterium-mediated transformation
Agrobacterium tumefaciens, a gram-negative plant pathogen belonging to the family Rhizobiaceae, is the causative agent of crown gall disease, which can affect many plant species including agronomically important ones.
-
Chemical genetic approaches for target validation
Drug development is a time- and resource-consuming process that starts with the discovery and validation of a (protein) target that contributes to pathogenesis or disease progression.
-
Systems pharmacology of the endocannabinoid system
What are the functions of the endocannabinoid system?
-
Visual analytics for spatially-resolved omics data at single cell resolution: Methods and Applications
The deeper understanding of an organism's pathology is important for developing treatments. Over centuries of systematic research, clinical researchers have demonstrated that the more information they acquire about the cellular properties and their organisation in the tissue, the better they can understand…
- Martina Huber Lab - EPR Group
-
Strategy
The Division of Systems Pharmacology and Pharmacy (SPP) aims to develop precision medicine approaches to characterize and predict variation in treatment response and enhance translational drug development strategies.
-
Sybil-AA: Systems Biology of Alcohol Addiction
The Horizon 2020 project Sybil-AA (Systems Biology of Alcohol Addiction) focuses on modeling and validating disease state networks in human and animal brains for understanding pathophysiology, predicting outcomes and improving therapy in alcohol addiction. Alcohol addiction, the most severe form of…
-
Exploring chemical space in covalent and competitive glycosidase inhibitor design
Glycoside hydrolases (glycosidases/GHs) are widely abundant enzymes in all kingdoms of life and are important biocatalysts that catalyze the hydrolysis of glycosidic linkages in oligo/polysaccharides, glycoproteins and glycolipids with tremendous efficiency
-
Lipid signaling and inflammation: metabolomics for better diagnosis and treatment strategy
Lipid signaling is an essential biological event/process in a plethora of pathophysiological conditions. The underlying idea of this thesis is that many of the roles and the complex interplay of the individual signaling lipids in inflammatory processes and related conditions in health and disease is…
-
Systems Pharmacology
The aim of the research programme Systems Pharmacology lies in the development of personalised medicine strategies, and development of new systems-based approaches in translational and clinical pharmacology.
-
Development of formulation for treatment of Atopic Eczema
description that google uses to depict when in presented in search results
-
Design and development of conformational inhibitors and activity-based probes for retaining glycosidases
Glycosidases are essential in fundamental biological processes and are responsible for the degradation of most (oligo)saccharides, glycolipids and glycoproteins.
-
Cell Therapy
Decision support tool for cell therapy commercialization and business development