2,086 search results for “disease prevention” in the Public website
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Quantitative pharmacological modelling for optimizing treatment of sepsis
Sepsis is a life-threatening condition caused by a dysregulated host response to infection, it is associated with significant morbidity, mortality, and with a high financial burden on global healthcare systems. Bacterial infections are the primary cause of sepsis, but the growing prevalence of antimicrobial…
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Bioengineering and biophysics of viral hemorrhagic fever
Viral hemorrhagic fever (VHF) is a group of acute diseases caused by highly infectious viruses including Ebola, Lassa, Dengue viruses. Its high mortality rate poses high risk to public health, however, studies on VHF have been hampered due to the non-availability of proper models and incomplete knowledge…
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Regulation of autophagy-related mechanisms during bacterial infection
Autophagy is a fundamental degradative process, maintaining cellular homeostasis and functions in host defense against intracellular pathogens, including mycobacteria and Salmonella.
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Bioarchaeology
Bioarchaeology covers the study of all biological remains from archaeological sites.
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In vitro and in vivo evaluation of synergistic and opposing effects of Chinese herbal medicine and natural compounds on immuno-modulation.
Can we link multiple components from herbal extracts with their biological activities?
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Phenotypic screening with 3D cell-based assays
Traditional drug discovery approaches have been hampered by (in vitro) cell-culture models that poorly represent the situation in the human body.
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A History of Plague in Java, 1911–1942
In A History of Plague in Java, 1911–1942, Maurits Bastiaan Meerwijk demonstrates how the official response to the 1911 outbreak of plague in Malang led to one of the most invasive health interventions in Dutch colonial Indonesia.
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Topic: E-health
The research connected to this topic is related to E-health.
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Chemical Tools to Illuminate N-acylphosphatidylethanolamine Biosynthesis
This thesis describes the development and optimization of the first molecular tools to study the enzyme PLA2G4E.
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Target Discovery
The goal of target discovery is to identify and validate proteins and biological pathways that are involved in the disease process. Modulating these target proteins and pathways with small molecules, therapeutic proteins or other biomolecules (e.g. mRNA) could deliver an effective and safe drug or v…
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Modulation of leukocyte homeostasis in atherosclerosis
Promotores: Prof.dr. E.A.L. Biessen, Prof.dr. T.J.C. van Berkel
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Analysis of sub-visible particles in complex injectable formulations
Promotors: W. Jiskoot; G.J. Witkamp, Co-promotor: M.R. Nejadnik
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The endocannabinoid system in zebrafish larvae
In this thesis, we have studied the potential of the zebrafish larval model in studying the ECS, as a complementary model to the existing rodent models.
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Research
Although there has been an increase in the research into brain function and dysfunction in relation to stress and emotions, there are still many unanswered questions.
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Macromolecular Biochemistry
Macromolecular Biochemistry is a section of the Leiden Institute of Chemistry at Leiden University, comprising the PIs Marcellus Ubbink, Remus Dame, Aimee Boyle, Lars Jeuken and Anne Wentink.
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Modern Drug Discovery
How are new drugs developed? This question is central to the Minor Modern Drug Discovery (MDD), which covers the entire trajectory from disease to drug molecule and vice versa. The various research groups involved offer a complementary and interdisciplinary perspective by connecting the diverse subjects…
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Human Evolution
This multidisciplinary minor provides students with knowledge on how and why humans became the way they are. The minor focuses on the evolution of the species Homo sapiens from other hominin lineages and animal ancestors, and on the various factors shaping this process. Not only is human evolution of…
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Continuing your studies
LUC graduates have an internationally-recognised Bachelors honours degree (BA/BSc) that qualifies them to apply for competitive programmes at top research universities. Over 90% of our alumni continue their studies into a master programme.
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Fulltime programme
The below schedule gives an overview of the curriculum of the one year fulltime master's programme Health, Ageing and Society for 2024-2025.
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Innovative sample preparation and handling strategies for automated and high-throughput metabolomics
Metabolomics has the potential to play a pivotal role in understanding disease onset and progression, and ultimately personalized treatments. One of its major challenges is its large-scale implementation, which is necessary to deal with the high variability of the metabolome. In this work we have developed…
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Research groups
The research at The Metabolomics & Analytics Centre is centered around developing innovating analytical methods to enable metabolomics-driven systems biology in personalized health strategies.
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Research
Biotherapeutics or biologics, such as proteins, peptides, and nucleic acids, comprise an increasing share of the pharmaceutical market, whilst offering new therapies for difficult-to-treat diseases. Most notable is their contribution to the vaccination efforts during the COVID-19 pandemic. In most cases,…
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Occupational health in the Emergency Department: A study on work-related factors and health/well-being in nurses and doctors in 19 Emergency
Occupational health in the Emergency Department
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Social Safety
Social safety is all about creating a supportive community
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Francesco Ragazzi, Students as suspects?
Could policies aimed at preventing radicalisation undermine the very trust and social cohesion they aim to strengthen?
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Is thyroid status a common denominator of age-related disease?
PhD defence
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LED3 Lecture: Organoids to model human health and disease in vitro
Lecture
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Major international study links genes to brain structural changes over time
There seem to be genes that influence how our brains develop over time. A large international consortium has discovered this with an extensive study. The results of the study were recently published in Nature Neuroscience.
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Erik Danen part of NWO Perspectief grant for organ-on-chip
A consortium of research groups, including that of LACDR professor Erik Danen, will use an NWO Perspective grant of nearly five million euros to build a universal standard for organ-on-chip models. They aim to stimulate the application of these chips in the biomedical and pharmaceutical industry. Danen…
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for imaging and analysis of hydrolase function in Cancer, Infectious Diseases and the microbiome
Lecture
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Joining hands to advance Dutch microscopy
Advanced microscopy to understand life and fight disease: that’s the goal of the new NL-BioImaging network that will develop and integrate state-of-the-art microscopy technologies and services. Researchers from all Dutch universities, including Leiden University and the Leiden University Medical Centre,…
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The Centre for Digital\\Jurisprudence
Online platforms such as YouTube, Facebook, and X (formerly Twitter) have become part and parcel of everyday media use. Journalists incorporate posts from politicians into newspaper reports, scientists share their insights in short posts or videos, and the judiciary uses social media to explain their…
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Foreign fighters
Understanding what motivates foreign fighters to go and fight in war zones and analysing their social environment offers a basis for preventing them from going.
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The Leiden Family Lab study on Social Anxiety Disorder
Social anxiety runs in families, but the neurobiology underlying this genetic vulnerability is until now largely unknown. The unique Leiden Family Lab study on Social Anxiety Disorder (LFLSAD) aims to broaden our knowledge with respect to this genetic susceptibility.
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Just Future
Which key factors contribute to effective land justice pathways for the protection of people’s land rights and prevention of conflict?
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Education
The Institute of Security and Global Affairs (ISGA) offers courses at both bachelor’s and master’s level. There are also minors, online learning and courses for professionals.
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About the programme
The programme of Parenting and Child Development consists of four substantive courses devoted to the following subjects:
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EUREX: European Registry of Exonerations to learn from miscarriages of justice
The European Registry of Exonerations database provides an overview of miscarriages of justice in Europe with a view to preventing future errors.
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Quantification in untargeted mass spectrometry-based metabolomics
Promotor: Prof.dr. T. Hankemeier, Co-promotor: T.H. Reijmers
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Allosteric modulation and ligand binding kinetics at the Kv11.1 channel
Promotor: Prof.dr. A.P. IJzerman, Co-Promotor: L.H. Heitman
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Leiden Institute for Brain and Cognition
The Leiden Institute for Brain and Cognition (LIBC) is a network focusing on science valorisation and outreach, stimulating interdisciplinary exchange of knowledge and expertise on topics related to brain and cognition.
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Healthy Society
The theme 'Healthy Society' is one of the focal points of the Faculty of Social and Behavioural Sciences (FSW).
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Current and next generation influenza vaccines: Formulation and production strategies
Vaccination is the most effective method to prevent influenza infection. However, current influenza vaccines have several limitations. Relatively long production times, limited vaccine capacity, moderate efficacy in certain populations and lack of cross-reactivity are important issues that need to be…
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Billing address
Read how to submit your invoice and how to ensure that payment is not delayed.
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Buccal and sublingual vaccine delivery
Because of their large surface area and immunological competence, mucosal tissues are attractive administration and target sites for vaccination.
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Ebifananyi. On photographs and telling histories from and about Uganda
In Luganda, the widest spoken minority language in East African country Uganda, the word for photographs is Ebifananyi. However, ebifananyi does not, contrary to the etymology of the word photographs, relate to light writings. Ebifananyi instead means things that look like something else. Ebifananyi…
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Dyslipidemia at the crossroad of the skin barrier and the arterial wall
The research described in this thesis shows that hypercholesterolemia, a well-established risk factor for atherosclerosis, can impact skin lipid pool and barrier function already at young age. In the field of atherosclerosis, we showed that the small peptide Lyp-1 can be used as a targeting molecule…
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Resistance to PARP inhibition by DNA damage response alterations in BRCA1/2-deficient tumors
Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.
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Crime victims and the police
On 1 February 2018 Nathalie-Sharon Koster defended her doctoral thesis ‘Crime victims and the police’. The doctoral research was supervised by Professor J.P. van der Leun and M.J.J. Kunst.