2,362 search results for “drug research” in the Public website
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Binding kinetics
A tantalizing concept that has emerged in our recent research is binding kinetics. An important parameter is residence time (RT), a direct reflection of how long a drug stays bound to its target. This parameter is of crucial importance, because drug action lasts only as long as the receptor-ligand complex…
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‘A revolution is coming in treatments for neurodegenerative diseases’
Professor by Special Appointment of Clinical Neuropharmacology Geert Jan Groeneveld will deliver his inaugural lecture entitled ‘The importance of the biomarker’ on 11 March 2022. According to him, new genetic knowledge will revolutionise drug research.
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Ukraine
This is an Erasmus+ International Credit Mobility project of the Faculty of Sciences with one partner in Ukraine.
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Development of novel anti-cancer strategies utilizing the zebrafish xenograft model
In this thesis, we will utilize embryonic zebrafish tumour models to understand the interaction between engrafted human cancer cells and macrophages from the host, test drug administration modalities and anti-cancer efficacies of newly-developed PDT and PACT compounds, and test a light-triggered liposomal…
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Roos van Oosten
Faculteit Archeologie
r.m.r.van.oosten@arch.leidenuniv.nl | +31 71 527 2448
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Harmen van der Veer
Faculteit der Sociale Wetenschappen
h.a.a.van.der.veer@fsw.leidenuniv.nl | +31 71 527 2727
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Boya Li
Faculteit der Sociale Wetenschappen
b.li@fsw.leidenuniv.nl | +31 71 527 2727
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Anne Hafkemeijer
Faculteit der Sociale Wetenschappen
a.hafkemeijer@fsw.leidenuniv.nl | +31 71 527 1375
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Joop van Holsteijn
Faculteit der Sociale Wetenschappen
holsteyn@fsw.leidenuniv.nl | +31 71 527 3954
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Research
Research in the POD-group addresses all features of random phenomena – modelling, structuring, analysis, control, optimisation – and covers both fundamental and applied aspects.
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Research
Within the Chinese medicine, more than 80% of the constituents of the preparations are derived from plants. Like any other organism, plants are constantly interacting with their changing and often harsh environment during the various phases of their life cycle.
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Research
The research of the Mathematical Institute is driven by the curiosity of its members and has many internal and external connections. It can be characterised as fundamental but with an open attitude towards applications.
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More effective blocking of CCR2 receptor
The discovery of new medicines is a tedious and lengthy process. On average, over 10,000 molecules need to be studied for one to become a drug and reach the patient. Part of that process are the very costly clinical trials in humans, and candidate drugs often fail due to side effects or lack of efficacy.…
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Doris Jacobs
Dr. Doris M. Jacobs, Lead Scientist at Unilever R&D, Wageningen, The Netherlands.
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Research
At the division of Biopharmaceutics, we aim to develop and test new therapeutic approaches to limit or even prevent the development of atherosclerosis in order to reduce the number of acute cardiovascular syndromes such as myocardial infarction or stroke.
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Research
The research conducted is centred around three themes. Within the different themes a multi-level approach is used, focussing on issues at the level of the health care system, the level of organizations and networks of organizations and at professionals within organisations.
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Research
PBDL favors multidisciplinary research. Depending on the problems under investigation, PBDL establishes collaborations between experts from for example molecular genetics, molecular and electro cell physiology, biochemistry, organic chemistry, analytical mathematics, mathematical statistics and computational…
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Research
Research framework CIAS
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Optimizing antifungal treatment through pharmacometrics: dosing considerations to enhance outcome
Fungal infections pose a significant threat to individuals with compromised immune systems and despite advancements in diagnosis and treatment, they continue to jeopardize patient’s health.
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Illuminating N-acylethanolamine biosynthesis with new chemical tools
In this thesis, the discovery and optimization is described of chemical tools to study the N-acylethanolamine (NAE) biosynthetic pathway.
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In vivo modelling of Ewing sarcoma in zebrafish
Promotores: Prof.dr. P.C.W. Hogendoorn & Prof.dr. H.P. Spaink, Co-promotor: Dr. B.E. Snaar-Jagalska
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Cancer chess: molecular insights into PARP inhibitor resistance
The clinical potential of applying synthetic lethality to cancer treatment is famously demonstrated by the BRCA1/PARP1 paradigm: a tumor specific defect in BRCA1 – a component of the DNA double-strand break (DSB) repair pathway homologous recombination (HR) – results in a remarkable sensitivity to PARP1…
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NACTAR: The lugdunomycins: a new class of polyketide antibiotics with unique chemical scaffold
Aim of the proposal is to develop lugdunomycin into a drug candidate able to treat infectious diseases caused by multi-drug resistant pathogens.
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Amphiphilic miktoarm star copolymers
Within this project, PeptoMiktoStars were realized through an orthogonal protecting group strategy and should be investigated further regarding their potential as drug delivery systems in the field of drug delivery to inflamed areas in cancer, bacterial infections or autoimmune diseases.
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Research
LUCSoR has chairs in Comparative Religion, Islam in the West, Christianity, and Judaism. Main areas of expertise include ancient Mesopotamian religions, the Enlightenment, Islam in the West, and new spiritual movements.
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Research
The programme group Research Methods and Statistics offers support to researchers from a variety of research projects within Education and Child Studies.
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Development of novel metabolomics & systems pharmacology concepts to realize personalized medicine
The predication of the effect (efficiency and toxicity) of a drug in a patient is very important in (i) clinical decision support and (ii) the development of novel drug treatments.
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Contact
Division contact information & address
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Liesbeth de Lange wins Lewis B. Sheiner Career Prize
Pharmacologist Liesbeth de Lange has won the Lewis B. Sheiner Lecturer Award from the International Society of Pharmacometrics (ISoP). As Professor of Predictive Pharmacology she is working, among other things, on a mathematical model that can predict drug concentrations in the brain. On the occasion…
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Research Schools
Many researchers of the Faculty of Science are members of a research school related to their area of expertise. Research schools aim at collaboration of researchers from different faculties in the same university (interfaculty schools) or in different universities (interuniversity schools).
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CCLS Past Events
On this page you can find information about previous CCLS events.
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Novel chemical tools for target validation in neuroinflammation
In what way can new tools and techniques be used to develop drug candidates for the treatment of neurological disorders?
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The activation mechanisms of G protein-coupled receptors: the case of the adenosine A2B and HCA2/3 receptors
Promotor: A.P. IJzerman
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Dosing considerations for preterm neonates: from pharmacometrics to clinical practice
Prematurely born neonates require, amongst others, pharmaceutical therapy. Dosing guidelines for these therapies are often based on data from term born neonates or older infants, while these are not necessarily similar to prematurely born neonates.
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Research facilities
Access to high-quality research facilities is essential to research success. That is why Leiden University makes its research facilities available to researchers from the business community, knowledge institutions and universities.
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Research software
The term research software encompasses many different things: source code files, algorithms, scripts, computational workflows and programs that were created during the research process or for a research purpose.
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Metabolomics Facility officially in operation
The Metabolomics Facility of Leiden University is now officially in operation to prevent disease and to improve health throughout the human lifespan.
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The Netherlands becomes global player organ-on-chip technology
Organ-on-chip technology is used in drug research and customized treatments for patients. Research Institutes and industry join forces within the Institute for human Organ and Disease Model Technologies (hDMT) that was officially launched on May 18. Combining facilities, people and expertise will allow…
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Research
Currently, Navigation Lab Leiden works on three main themes: navigation ability, spatial abilities, novel techniques in neuropsychology.
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Research areas
Within the Graduate School you can conduct your PhD research in a wide range of subjects across the Social and Behavioural Sciences, with five distinct research areas offered by its Institutes.
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Postdoctoral Research
It is essential for researchers to be able to obtain independent research funding to advance in their careers.
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Coiled-coil biomaterials for biological applications
This dissertation contains four works during my PhD. Different biomaterials have been designed based on coiled-coil peptides. These biomaterials have a range of applications, inclusing drug delivery, cell sorting to cell-cell fusion.
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The endocannabinoid system in zebrafish larvae
In this thesis, we have studied the potential of the zebrafish larval model in studying the ECS, as a complementary model to the existing rodent models.
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Postdoctoral Research
It is essential for researchers to be able to obtain independent research funding in order to advance in their career.
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Research assessment
As part of the process of safeguarding the quality of our research, our institutes are audited regularly by a committee of external experts.
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Guest Researcher
We welcome a new round of advanced researchers (post-MA) to apply to the institute's guest researchers positions.
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Visiting Researchers
Leiden Law School welcomes visiting researchers who would like to spend time with us furthering their (PhD) research. As a visiting researcher, you can make use of our extensive library, our digital resources and the expertise of the Law School’s institutes.
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Imaging and Bioinformatics
On the basis of the characteristic aspects of a picture, certain computers can tell us what the picture is showing. They can learn this in the same way that young children are able to learn to recognize images. Further improving these techniques opens the way to a whole range of new applications. Biology…
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Research opportunities
For students who wish to conduct short-term research at Leiden University, there are a number of options available.
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Affiliated Researchers
The GTGC network currently spans over 200 researchers across 6 faculties at Leiden University. We especially foster thematic interfaculty collaborations on a wide variety of global transformations and governance challenges.