2,027 search results for “this week s discoveries” in the Public website
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Mechanistic modelling of drug target binding kinetics as determinant of the time course of drug action in vivo
Drug-target binding kinetics determine the time course of the central event in pharmacotherapy: Drug-target interaction.
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No classes and working from home: here’s what our week looked like
From the new Hortus botanicus podcast to conference call bingo: all the students, lecturers and other members of staff from Leiden University had to switch at breakneck speed to working and studying from home this week. That meant decluttering offices, getting your head around remote teaching and installing…
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In pictures: kick-off Healthy University Week
On Monday 28 October, we celebrated the start of Healthy University Week 2019. During this week, students and staff of Leiden University can follow workshops to help them adopt a healthier lifestyle.
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Anthe Janssen
Science
a.p.a.janssen@lic.leidenuniv.nl | +31 71 527 4362
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Discovery of a unique silver bowl from the Early Middle Ages
On an excavation site in Oegstgeest Leiden University archaeologists discovered a very rare silver bowl from the first half of the seventh century. The bowl is decorated with gold-plated representations of animals and plants and inlaid with semi-precious stones. The discovery suggests the existence…
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Chemical Biology
Chemical biology research at the Leiden Institute of Chemistry is aimed at understanding biological processes at the molecular level to strengthen the knowledge base of human health and disease. The approach to achieve this goal is a fundamental chemical one; with the aid of chemical probes biological…
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Sensing Transport
Solute carrier (SLC) transporters are a large and diverse class of relatively understudied transmembrane proteins.
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Towards improved drug action : target binding kinetics and functional efficacy at the mGlu2 receptor
During the course of drug discovery translational steps are made.
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Flurry of new discoveries as incredible new image revealing 4.4 million galaxies is made public
Over a seven year period an international team of scientists has mapped more than a quarter of the northern sky using the Low Frequency Array (LOFAR), a pan-European radio telescope. From Leiden, Astronomer Timothy Shimwell and Huub Röttgering, among others, are involved. It reveals an astonishingly…
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Master's application and admission
Find out how to apply for Drug Discovery and Safety at Leiden University by following our step-by-step guide.
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Hypoxic Signalling and Tuberculosis
IBL-researcher Phil Elks in the group of Annemarie Meijer won the Cell Observatory Publication of the Year 2013. He received the award for his paper in PLoS Pathogens, showing that activation of hypoxia signaling protects against mycobacterial infection.
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Chemical tools to study the cannabinoid receptor type 2
The cannabinoid receptor type 2 (CB2R) is associated with several inflammatory diseases with an unmet medical need (e.g. Alzheimers, multiple sclerosis, reumatoid arthritis). Development of new chemical biology strategies to study this protein is essential to aid future development of drugs for these…
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Registration open for introduction weeks: what to expect
Will you be coming to study at our university? If so, we want you to feel welcome. We therefore offer three different introduction weeks, with something for everyone: one in Leiden, one in The Hague and one for internationals. Register soon!
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Sebastian Pomplun
Science
s.j.pomplun@lacdr.leidenuniv.nl | +31 71 527 4651
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How EL CID week can go ahead after all
When the government introduced its corona measures, the future of EL CID suddenly looked uncertain. But this annual introduction week will start on 5 August after all. How did the EL CID board pull this off? A glimpse behind the scenes through the eyes of chair Mirte Haanappel.
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iGEM team Leiden 2016
Using E. coli bacteria to convert a toxic compound in the soil on Mars into oxygen to make life on the planet possible. A team of thirteen Leiden students are taking part in the annual iGEM competition with an entry based on this idea. iGEM is an international competition for students where they use…
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Minister Dijkgraaf visits OWL international introduction week
On Monday, Minister of Education, Culture and Science Robbert Dijkgraaf attended the start of Orientation Week Leiden (OWL), the introduction week for international students at Leiden University. He welcomed the students and spoke with them about their ambitions and the problems they face.
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Fluorescence Polarization Activity-Based Protein Profiling on Retaining Glycosidases
Glycosidases are important enzymes in the turnover of polysaccharides and glycoconjugates, and are involved in a range of human pathologies including genetic disorders such as Gaucher and Pompe disease, but also in various cancers.
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Record number of international students join introduction week
From Afghanistan to South Africa: 1,144 international students, including refugees from Syria, are taking part in the Orientation Week Leiden.
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Illuminating N-acylethanolamine biosynthesis with new chemical tools
In this thesis, the discovery and optimization is described of chemical tools to study the N-acylethanolamine (NAE) biosynthetic pathway.
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National Week without Meat
National Week Withouth Meat: March 9th-15th @ Leiden University PURE restaurants
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Week Zonder Vlees
Nationale Week Zonder Vlees is een landelijke campagne en wordt breed gedragen door diverse partners uit de voedselindustrie!⠀
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Singing Basics: A Vocal Discovery in 6 weeks
Arts and leisure
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Make your choice! Three introduction weeks for students at Leiden University
Leiden or The Hague? Dutch or English? These two questions decide which introduction week new students at Leiden University can best choose: EL CID, HOP or OWL.
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Make your choice! Three introduction weeks for students at Leiden University
Leiden or The Hague? Dutch or English? These two questions decide which introduction week new students at Leiden University can best choose: EL CID, HOP or OWL.
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Make your choice! Three introduction weeks for students at Leiden University
Leiden or The Hague? Dutch or English? These two questions decide which introduction week new students at Leiden University can best choose: EL CID, HOP or OWL.
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Webinar Week: reaching out to prospective master's students
Not all students who are thinking of doing a master’s programme at Leiden University can come to the Master’s Open Day. Hence the first Webinar Week, from 2 to 5 December. ‘Online video is the way to reach today’s generation of prospective master’s students.’
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Come visit us at the Online Master's Week
On Friday March 12 2021.
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Zebrafish: a new engraft model to study Ewing sarcoma progression
Can zebrafish provide a fast, sensitive in vivo vertebrate model for identifying novel mechanisms of Ewing sarcoma progression and for development of new anticancer compounds in a time- and cost-effective manner?
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Marijana Vujosevic
Faculty of Humanities
m.vujosevic@hum.leidenuniv.nl | +31 71 527 2727
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Ann Skelton
Faculteit Rechtsgeleerdheid
a.m.skelton@law.leidenuniv.nl | +31 71 527 2727
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Mariëlle Bruning
Faculteit Rechtsgeleerdheid
m.r.bruning@law.leidenuniv.nl | +31 71 527 8913
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Ursula Kilkelly
Faculteit Rechtsgeleerdheid
u.kilkelly@law.leidenuniv.nl | +31 71 527 2727
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Jessie Pool
Faculteit Rechtsgeleerdheid
j.m.w.pool@law.leidenuniv.nl | +31 71 527 4035
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Sophy Baird
Faculteit Rechtsgeleerdheid
s.b.baird@law.leidenuniv.nl | +31 71 527 2727
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Lucy Opoka
Faculteit Rechtsgeleerdheid
l.a.opoka@law.leidenuniv.nl | +31 71 527 6438
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Katrien Klep
Faculteit Rechtsgeleerdheid
k.f.m.klep@law.leidenuniv.nl | +31 71 527 1325
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Ton Liefaard
Faculteit Rechtsgeleerdheid
t.liefaard@law.leidenuniv.nl | +31 71 527 2727
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Affinity-based profiling of the adenosine receptors
The adenosine receptors are proteins that reside in the extracellular membranes of cells. Activation of adenosine receptors plays a role in many physiological and pathological processes, such as immune responses and cancers.
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Role of leukocytes in metastasis formation in a zebrafish
How do macrophages and neutrophils contribute to metastatic onset?
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First discovery of methanol in a warm planet-forming disk
An international team of researchers led by Alice Booth (Leiden University, the Netherlands) have discovered methanol in the warm part of a planet-forming disk. The methanol cannot have been produced there and must have originated in the cold gas clouds from which the star and the disk formed. Thus,…
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Robust rules for prediction and description.
In this work, we attempt to answer the question:
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Predicting early Alzheimer's disease stage in human
A new research line is the development of liquid biopsy fingerprints to predict early Alzheimer’s disease (AD) stage in human in readily accessible body fluids in human (in collaboration with: Dr. Geert-Jan Groeneveld, CHDR; Prof. Elga de Vries, Free University Medical Center; and others).
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Laura Heitman
Science
l.h.heitman@lacdr.leidenuniv.nl | +31 71 527 4558
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SysMedPD: Systems Medicine of Mitochondrial Parkinson's Disease
The overall objective of this project is to identify novel drug candidates that are capable of slowing down the progression of neurodegeneration in the subset of Parkinson’s disease (PD) patients with overt mitochondrial dysfunction. Multimodal phenotypic characterisation of cohorts of monogenic PD…
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Chemical genetic approaches for target validation
Drug development is a time- and resource-consuming process that starts with the discovery and validation of a (protein) target that contributes to pathogenesis or disease progression.
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FishForPharma: Training network on zebrafish infection models for pharmaceutical screens
How can zebrafish models be used to gain a better understanding of host-pathogen interaction mechanisms and to screen new drugs for infectious disease treatment?
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Mirjam Sombroek-van Doorm
Faculteit Rechtsgeleerdheid
m.p.sombroek@law.leidenuniv.nl | +31 71 527 2727
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Developing metabolomics for a systems biology approach to understand Parkinson's disease
Neurodegenerative diseases, including Parkinson’s disease (PD), are increasing in prevalence due to the aging population. Despite extensive study, these diseases are still not fully understood and the lack of personalised treatment options that can target the cause of the diseases, rather than the symptoms,…
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Archive
Our Talents and Discoveries is a yearly publication by the Faculty of Science of Leiden University, published since 2003. You can read all the editions online. Note that the original publication was in Dutch; the original title translates as 'What we are proud of'.