2,530 search results for “drug research” in the Public website
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First-pass and systemic metabolism of cytochrome P450 3A substrates in neonates, infants, and children
Growth and development affect the metabolism of drugs administered to neonates, infants, and children.
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Discovery of novel inhibitors to investigate diacylglycerol lipases and α/β hydrolase domain 16A
Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt
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Leiden researchers join forces against tuberculosis
About one and a half million people worldwide die each year from tuberculosis. For thirty years, therapy with antibiotics has been the same, while it takes far too long and can lead to resistant pathogens. Leiden researchers from four institutes are now joining forces to develop more effective and efficient…
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Horizon Europe grant for research into personalised treatment for high blood pressure
Professor Thomas Hankemeier and his international research team HYPERMARKER have received a 10m-euro grant from Horizon Europe and UK Research and Innovation.
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Medicine development is hunting magic bullets
Medicines are becoming increasingly precise and innovative, but at the same time increasingly expensive. With their innovations, it is up to universities to increase competition, thus causing prices to drop. This is what newly appointed Professor of Biomolecular Analysis Hubertus Irth argues. His inaugural…
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Reversing cardiovascular diseases
How can the development of constrictions in the blood vessels be reversed?
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The molecular secrets of medicinal cannabis
Chronic pain, nausea or vomiting due to chemotherapy. If you suffer from such ailments, medicinal cannabis can be a godsend. Though a downside is that it can make patients high. Therefore, Leiden researchers from the Oncode Institute are investigating alternatives that do not make you high. In Nature…
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Vision
The Pharmacy research group focusses on the development of predictive models to improve clinical drug efficacy and safety. We work on clinical problems that require further mechanistic understanding and strive for ultimate benefit to patients.
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From discovery to business: 'In the lab, we often don't realise that we are working to help an immense number of patients'
'It gave our team a big boost to hear that our work was valuable,' says medical chemist Elmer Maurits about the moment they won the Venture Challenge. With their company Iprotics, they want to develop a drug that can better treat patients with autoimmune diseases and blood cancers. 25,000 euros of prize…
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Light relief
How can new compounds relieve cancer patients of severe side effects?
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Targeted biomolecule production for therapeutic use
We aim to develop a drug-delivery method based on the production of biomolecules directly at the target site.
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Personalized Medicine
Getting personal
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New resource for the modelling community
The Repository from the Drug Disease Model Resources (DDMoRe) consortium provides a home to a collection of computational models of disease and drug action that have been used in pharmaceutical and/or academic research. This publically available open-access resource will make it easier for researchers…
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Microbial Sciences
In the research programme Microbial Sciences we perform state-of-the-art research in the field of biotechnology and microbial sciences.
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Pharmacodynamics of analgesics and sedatives in neonates and infants
In neonates and infants, body size, enzyme pathways, and expression and function of receptors and (target) proteins are still developing.
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Hit Discovery
The goal of hit discovery is to identify suitable chemical starting points to modulate a drug target. A hit can be, a.o., a small molecule, a protein or mRNA. Hit identification is performed via rational design, genome mining, (targeted) library screening, or in silico approaches.
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€8.5m for research into healthy ageing and vitality
A large multidisciplinary team of experts on ageing has secured over €8.5m for a major study of which factors and solutions promote healthy ageing and increase vitality. The LUMC and the Leiden Academic Centre for Drug Research (LACDR) are two of the centres involved in this national research projec…
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BioTherapeutics
Research in the BioTherapeutics research programme is aimed at a smoother and speedier transition from preclinical research to pharmacological interventions, and the delivery of drugs in the human body by use of small molecules and biologics.
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Four bold Faculty of Science researchers receive NWO XS grants
Four scientists from the Faculty of Science will receive a grant of up to 50,000 euros in the Open Competition Domain Science - XS from science financier NWO. This category emphatically strives to encourage curiosity-driven and bold research involving a relatively quick analysis of a promising idea.…
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From descriptive to predictive pharmacology in children using semi-physiological population modelling: application to hepatic metabolism
Clearance is the most important pharmacokinetic parameter for drug dose selection. Pharmacokinetic information is typically first available in the adult population, and in general only limited pharmacokinetic data are available in children when drugs enter into the market. It is therefore of the utmost…
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Concepts and applications for evidence-based dosing in morbidly obese patients before and after weight loss surgery
Promotor: C.A.J. Knibbe, Co-promotores: H.P.A. van Dongen, B. van Ramshorst
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Strategy
The Division of Systems Pharmacology and Pharmacy (SPP) aims to develop precision medicine approaches to characterize and predict variation in treatment response and enhance translational drug development strategies.
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Hall of Fame 2023
In 2023, many of our students and staff won great prizes and secured important research grants.
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History
Life Sciences Artificial Intelligence Data Science
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Remarkable PhD research: diagnosing sepsis in premature babies
How can we diagnose the life-threatening condition sepsis in premature babies as quickly and accurately as possible? That is what PhD student Manchu Thangavelu from the Leiden Academic Centre for Drug Research (LACDR) wants to figure out.
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Development of hyaluronan-based dissolving microneedle arrays for dermal vaccination
Dissolving microneedles are a subgroup of microneedle types that completely dissolve within the skin. During this dissolving process the vaccine, stored in the needle matrix, is released into the skin.
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Coen Wirtz
Faculteit der Sociale Wetenschappen
c.wirtz@fsw.leidenuniv.nl | +31 71 527 3731
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Carolien Rieffe
Faculteit der Sociale Wetenschappen
crieffe@fsw.leidenuniv.nl | +31 71 527 3674
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Arash Pourebrahimi Andouhjerdi
Faculty Governance and Global Affairs
a.pourebrahimi.andouhjerdi@fgga.leidenuniv.nl | +31 70 800 9502
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Judith Bovée
Faculteit Geneeskunde
j.v.m.g.bovee@lumc.nl | +31 71 526 9111
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Gieneke Teeuwen
Faculteit Rechtsgeleerdheid
g.teeuwen@law.leidenuniv.nl | +31 71 527 2727
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Fenneke Sysling
Faculty of Humanities
f.h.sysling@hum.leidenuniv.nl | +31 71 527 2737
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Lisa Schreuders
Faculteit der Sociale Wetenschappen
e.schreuders@fsw.leidenuniv.nl | +31 71 527 2727
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Haye Geukes
Science
h.h.geukes@cml.leidenuniv.nl | +31 71 527 2727
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David Heyne
Faculteit der Sociale Wetenschappen
d.heyne@fsw.leidenuniv.nl | +31 71 527 2727
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Min Cho
Faculty Governance and Global Affairs
m.j.cho@luc.leidenuniv.nl | +31 70 800 9503
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Katy Wolstencroft
Science
k.j.wolstencroft@liacs.leidenuniv.nl | +31 71 527 8926
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Lucy Opoka
Faculteit Rechtsgeleerdheid
l.a.opoka@law.leidenuniv.nl | +31 71 527 6438
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Camille Lefebvre
Faculteit Rechtsgeleerdheid
c.l.lefebvre@law.leidenuniv.nl | +31 71 527 2727
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Eva Sievers
Science
e.m.sievers@cml.leidenuniv.nl | +31 71 527 2727
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Joram van Ketel
Faculteit Rechtsgeleerdheid
j.e.van.ketel@law.leidenuniv.nl | +31 71 527 7536
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Marieke Liem
Faculty Governance and Global Affairs
m.c.a.liem@fgga.leidenuniv.nl | +31 70 800 9935
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Kees Verduin
Faculteit der Sociale Wetenschappen
c.j.verduin@fsw.leidenuniv.nl | +31 71 527 2727
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Experimental Systems: Future Knowledge in Artistic Research
The experimental approach of science applied to artistic research
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Corpora Non Agunt Nisi Fixata: Ligand Receptor Binding Kinetics in G Protein-Coupled Receptors
The present thesis focuses on the pharmacological concept of drug-target interaction, which dates back to the beginning of modern pharmacology.
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EU awards 18 million euros for research into new antibiotics
An international consortium of research groups is aiming to develop novel antibiotics against the tuberculosis bacteria and two other deadly bacteria. The European Union has awarded a total of 18 million euros to the RespiriTB and RespiriNTM projects. Researchers from the Leiden University Medical Centre…
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Career prospects
Many students receive their first job offer during or right after their Business Studies internship. After graduating you can also aim for a career in Bio-Pharmaceutical research.
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Research
Research is meant to generate knowledge, in a rational and sensible way. Many research methods exist to do this, and creativity is an important factor. Our mission is to explore creative, playful, unexpected, and unconventional forms of academic research.
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Research
The Institute of Public Administration is one of the largest and oldest institutes of academic research and teaching in the field of public administration in the Netherlands. The Institute combines a solid international academic reputation with a central positioning among the international, national,…
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Research
Research at Leiden Law School means research at the highest level. Leiden Law School has eight broad research programmes and one specific ‘profile area’: Interaction between legal systems - which aims to understand the complex interaction between the various levels of jurisdiction and to solve the resulting…