1,609 search results for “mexican drug violence” in the Public website
-
Advanced in vitro models for studying drug induced toxicity
Promotor: Prof.dr. B. van de Water, Co-promotor: L.S. Price
-
Drug-target binding kinetics in vivo
A next, general pharmacological problem to be tackled is how drug-target binding kinetics in vivo, affects target occupancy as an important indicator of the time-course of drug effects.
-
Activity-based protein profiling in drug discovery
In the last decades, activity-based protein profiling (ABPP) has emerged as a powerful chemical tool that may aid the ever-challenging drug discovery process.
-
Drug use and harm reduction policies
Harm reduction in practice: a comparative analysis of the Dutch and Brazilian approach towards drug users.
-
Discovery of metastasis promoting candidate drug targets
Discovery of metastasis promoting candidate drug targets
-
Collective violence offenders and offending. The role of individual characteristics
On 29 September 2020, Tom van Ham defended his thesis 'Collective violence offenders and offending. The role of individual characteristics'. The doctoral research was supervised by Prof. A.A.J. Blokland, Prof. O.M.J. Adang (RUG) and Prof. Th.A.H. Doreleijers (VUMC).
-
Proving discriminatory violence at the European Court of Human Rights
On Tuesday 23 May 2017, Jasmina Mackic defended her doctoral thesis ‘Proving discriminatory violence at the European Court of Human Rights’. The supervisor of the research is Vice Dean and Professor of Public International Law Larissa van den Herik. A brief summary of her thesis is provided below.
-
Violence and the Mimetic Unconscious: Volume 2, The Affective Hypothesis
Representations of violence have subliminal contagious effects, but what kind of unconscious captures this imperceptible affective dynamic in the digital age?
-
Postdoc Computational Modeling for Drug Safety Prediction
Science, Leiden Academic Centre for Drug Research (LACDR)
-
The relation between communication and violence in the Guéra and Moyen –Chari regions (Chad) from 1940 to 2010
French title: Communication et violences dans le Guéra et le Moyen-Chari (Tchad) de 1940 à 2010. This research investigates the relationship between the introduction of new means of communication and violence experienced by the local populations in the Moyen-Chari and the Guéra regions in Chad from…
-
Crisis and Security Management: Governance of Violence (MSc)
Are you thinking about studying Crisis and Security Management: Governance of Violence? Learn more and watch the videos.
-
The Silent Majority: justice for child victims of violence
The position of child victims, globally and in Liberia and their right to physical and psychological recovery and social reintegration covered by art. 39 CRC.
-
Terror and the Legitimation of Violence: A Cross-National Analysis on the Relationship between Terrorism and Homicide Rates
This article written by Marieke Liem & Alexander Kamprad investigates the relationship between terrorism and interpersonal violence. They conducted cross-national analyses on the effects of terrorism mortality rates on homicide rates. Results showed that terrorism appears to be robustly and positively…
-
To explore the drug space smarter: Artificial intelligence in drug design for G protein-coupled receptors
Over several decades, a variety of computational methods for drug discovery have been proposed and applied in practice. With the accumulation of data and the development of machine learning methods, computational drug design methods have gradually shifted to a new paradigm, i.e. deep learning methods…
-
Pedagogies of Prohibition: Time, Education, and the War on Drugs in Rio de Janeiro’s Zona Norte
Benjamin Fogarty-Valenzuela published the article 'Pedagogies of Prohibition: Time, Education, and the War on Drugs in Rio de Janeiro’s Zona Norte' in Cultural Anthropology 37. The article’s three sections focus on three forms of temporal control—busyness, punctuality, and rhythm—and each demonstrates…
-
The Performative Force of Accented Speech: Language, Body, and Violence
This research examines the social, political, and cultural forces that structure people’s responses towards accented speech, and further uses the accent as a focal point to theorize the interrelation between language and body.
-
Pharmacogenomics in drug development: implementation and application of PKPD model based approaches
Promotor: Prof.dr. M. Danhof, Co-Promotor: J. de Jongh
-
Monitoring drug-related homicides: An assessment of existing data sources and potential for future monitoring
This project’s aim is to critically assess current homicide data sources in order to develop a proposal for long-term EU-level monitoring of DRH.
-
Computational Approaches to Disease, Signaling and Drug Targets
The Minor Computational Approaches to Disease, Signaling and Drug Targets (CADSDT) is focused on fundamental scientific research required for discovery of new drug targets and development of new drugs.
- Leiden Academic Centre for Drug Research
-
mRNA and drug delivery with lipid-based nanoparticles
This thesis focuses on the application of lipid-based nanomedicine in drug delivery, including small molecular antitumor drugs and biomacromolecules including mRNA, and evaluates their biological performance.
-
Quan/Qual analysis of drugs and metabolites in biological matrices
Can we develop a generic method for Quan/Qual analysis of small molecule drugs, their metabolites and endogenous metabolites in (pre-)clinical samples?
-
24-hour rhythms in drug exposure and effect
Although rarely considered by the pharmaceutical industry or clinicians, 24-hour rhythms in physiology are a factor of potential influence on the pharmacokinetics and pharmacodynamics of drugs.
-
Spatial (3-D) CNS drug distribution in vivo
Another research line is the development of a spatial CNS drug distribution model, by ultimately including the 3-dimensional anatomical organization of the CNS.
-
Why don't drugs make it to the market?
How can we extend the drug residence time to combat diseases more effectively?
-
Katharina Krüsselmann
Faculty Governance and Global Affairs
k.krusselmann@fgga.leidenuniv.nl | +31 70 800 9192
-
Proteins in harmony: Tuning selectivity in early drug discovery
This thesis describes the importance of being able to control the selectivity of potential drug candidates.
-
Towards improved drug action : target binding kinetics and functional efficacy at the mGlu2 receptor
During the course of drug discovery translational steps are made.
-
The Role of Target Binding Kinetics in Drug Discovery
Source: ChemMedChem (2015)
-
Microengineered Human Blood Vessels For Next Generation Drug Discovery
Heart failure is a major health care problem with high mortality.
-
Antibiotic combination therapies against drug resistant Gram negative pathogens
Can effective synergists be identified to enhance the effect of antibiotics against Gram negative pathogens?
-
Scientific computing for Drug Discovery in Python and/or R
Data analysis with Python and R are rapidly becoming essential skills for modern scientists. Therefore, we are offering courses to develop your scientific computing skills. Those courses are optional for LACDR PhD candidates.
-
New imaging technology to assess early drug success
Human and animal cells are very complex: very different chemical processes are going on at the same time, but they are separated from each other because the cells are divided in compartments. These compartments may also have a profound effect on the potential efficacy of therapeutics, because the drug…
-
New publication: Proving Discriminatory Violence at the European Court of Human Rights
Jasmina Mačkić, Assistant Professor of Human Rights Law at the Europa Institute, has published her book, Proving Discriminatory Violence at the European Court of Human Rights. This work is based on her doctoral dissertation, which she defended in May 2017 and which was funded by the Netherlands Organisation…
-
GMP facility for innovative drugs (KFT-J10 / IGFL)
The GMP Facility facilitates development and production of Advanced Therapy Medicinal Products (ATMPs) and chemical (peptide) synthesis.
-
vesicles: An efficient membrane biophysical tool and its application in drug delivery studies
Promotor: A. Kros
-
Digital warfare in the Sahel: popular networks of war and Cultural Violence
This interdisciplinary study focuses on (trans)national ethnic and popular networks, combining historical-ethnographic and computational methods to understand the ‘workings’ of networked conflict interfering in the increasingly violent conflict in the Sahel (Africa) and beyond. The project focuses on…
-
Embedded Remembering: Memory Culture of the 1965 Violence in Rural East Java
Grace Leksana defended her thesis on 26 May 2020.
-
Rebels and Conflict Escalation: Explaining the Rise and Decline in Violence
Violence during war often involves upswings and downturns that have, to date, been insufficiently explained. Why does violence at a particular point in time increase in intensity and why do actors in war decrease the level of violence at other points? Duyvesteyn discusses the potential explanatory variables…
-
2010 Important gift of the Mexican Embassy
The Mexican embassy, represented by the cultural attaché, Mr. José Manuel Springer, donated to the Faculty of Archaeology a voluminous publication of detailed maps of the historical and contemporary distribution of the indigenous languages of Mexico: “Catálogo de Lenguas Indígenas Mexicanas, Cartografía…
-
Of ticking bombs: Western security services against political violence and terrorism
How have British, Dutch, and German security services dealt with political violence and terrorism since the late 1960s; to what extent did they consider these new phenomena as a task and how have they developed activities in order to counter these security threats?
-
Beyond the Pale: Dutch Extreme Violence in the Indonesian War of Independence, 1945-1949
On 17 August 1945, two days after the Japanese surrender that also brought an end to the Second World War in Asia, Indonesia declared its independence. The declaration was not recognized by the Netherlands, which resorted to force in its attempt to take control of the inevitable process of decolonization.…
-
Activity-based protein profiling for drug discovery
Activity-based protein profiling (ABPP, also termed chemical proteomics), is one of the pillars of chemical biology, and at LED3 we have taken it to the next level. ABPP allows the assessment of protein function in live cells and tissues, which means that the activity of a complete protein family can…
-
Transnational Pentecostalism in the Age of #MeToo: Sexual Violence and Harassment from Lagos to Los Angeles
This initiative is intended to support generative research collaborations between and among scholars located in different geographical regions who wish to pursue focused, joint projects in any area of the study of religion.
-
PhD Candidate: Strategic Violence by Non-State Actors (1,0 FTE)
Governance and Global Affairs, Institute of Security and Global Affairs
-
What sets extremists who use terrorist violence apart from those who do not?
This paper contributes on an increasing body of work on radicalisation. It specifically focuses on what distinguishes individuals whose behavioural radicalisation includes involvement in terrorist violence from those whose behavioural radicalisation does not.
-
A chemical biology approach for targeting of ligand-drug conjugates
Promotores: Prof.dr. H. S. Overkleeft, Prof.dr. G. A. van der Marel
-
The Dutch and English East India Companies: Diplomacy, Trade and Violence in Early Modern Asia
The Dutch and English East India Companies were formidable organizations that were gifted with expansive powers that allowed them to conduct diplomacy, wage war and seize territorial possessions. But they did not move into an empty arena in which they were free to deploy these powers without resista…
-
Freedom and the Fifth Commandment. Catholic priests and political violence in Ireland, 1919-21
A new paperback edition of Brian Heffernan's book Freedom and the Fifth Commandment. Catholic priests and political violence in Ireland, 1919-21 was published by Manchester University Press in September 2016.
-
Systems pharmacokinetic models to the prediction of local CNS drug concentrations in human
Clinical development of drugs for central nervous system (CNS) disorders has been particularly challenging and still suffers from high attrition rates.