416 search results for “blood vessels” in the Public website
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The ANASTASIS project: Reviving Merovingian archaeology in the Netherlands
The goal of the ANASTASIS project is the analysis and publication of early medieval (Merovingian) cemeteries in the Netherlands (c. 500 – 750 AD).
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The End of our Third Decade (volume II)
Papers written on the occasion of the 30th anniversary of the institute of Prehistory, Volume II.
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Religion and Trade: Cross-Cultural Exchanges in World History, 1000-1900
This book published by Oxford University Press discusses religion and trade in world history.
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ForSeaDiscovery - Forest resources for Iberian empires: ecology and globalization in the age of discovery
An interdisciplinary and innovative research group combining History, underwater archaeology, GIS and wood provenancing methods.
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Flora in Utopias: On Thinking Through Moving Images
How do documentary moving images and fictional narratives involve and evolve each other?
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Veni grants for 16 Leiden researchers
Sixteen researchers at Leiden University are to receive a Veni grant from the Netherlands Organisation for Scientific Research (NWO). These awards offer promising young researchers the opportunity to further develop their own ideas over a period of three years.
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GRIPonMASH
GRIPonMASH will address the unmet public health need of reducing disease burden and comorbidities associated with Metabolic dysfunction-Associated Steatotic Liver Disease (MASLD).
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Shaping the pharmacokinetic landscape for renally cleared antibiotics in obesity
The prevalence of obesity (BMI >40 kg/m2) has increased rapidly over the recent years, not only in adults, but also in children and adolescents.
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Lab facilities Developmental and Educational Psychology
Social anxiety and factors determining school success in children. Brain development in relation to cognitive, social and emotional development in adolescence.
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Reactive Copolypept(o)ides as Novel Material for Systemic siRNA Delivery
The aim of the project is the development of polypept(o)ide-based delivery systems to use siRNA as systemic applicated therapeutic agent against e.g. solid tumors
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Dynastic Identity in Early Modern Europe - Rulers, Aristocrats and the Formation of Identities
Aristocratic dynasties have long been regarded as fundamental to the development of early modern society and government. Yet recent work by political historians has increasingly questioned the dominant role of ruling families in state formation, underlining instead the continued importance and independence…
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Molecular Signatures of the Evolving Immune Response in Mice following a Bordetella pertussis Infection
Worldwide resurgence of pertussis necessitates the need for improvement of pertussis vaccines and vaccination strategies.
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Magnetic Resonance Microimaging of Alzheimer's Disease
Alzheimer's disease (AD) is the most frequent neurodegenerative disorder and the primary cause of dementia. The neuropathological features of AD include the occurrence of senile plaques, neurofibrillary tangles, decreased synaptic density, and loss of neurons. An obstacle in the study and treatment…
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Measuring sulfur with satellites
Seagoing vessels may emit fewer and fewer harmful substances, but how do you measure whether they comply with the standards? The Dutch Environment and Transport Inspectorate (ILT) and the universities of Leiden and Wageningen are starting a joint study to detect the emission of sulfur and nitrogen dioxide…
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Athens
Athens is universally known as a symbol of democracy, philosophy, and ancient Greek aesthetics. Some of the most famous classical monuments, including the Parthenon and the temple of Hephaestus, can be found here.
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Research methods
Because we cannot directly ask babies about what they know or what they are thinking about, we must find smart and baby-friendly ways to figure it out! Below you can read about the different methods that we typically use in our studies.
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Healthy ageing
The elderly accept may minor discomforts like stiffer muscles and getting tired more quickly, but they do want to go to their children's birthdays independently. Preventive elderly care helps people with that. The goal is to let people grow old while maintaining their self-reliance and independence…
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Vici grants for seven researchers from Leiden University
From research on stellar winds to sign language: an impressive seven researchers from Leiden University will receive a prestigious Vici grant from the Dutch Research Council (NWO).
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Metabolomics and Analytics Centre
The ambition of the Metabolomics and Analytics Centre led by Thomas Hankemeier is to develop innovative analytical strategies for metabolomics-driven health monitoring and systems biology studies. Understanding the intricate balance between health, disease and adaptation to challenges relies on the…
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Publications
For a full overview of the publications of the Translational Immuno-Pharmacology group, visit the Google Scholar page.
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Medicine
The Faculty of Medicine
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Cationic liposomes loaded with a synthetic long Peptide and poly(i:C): a defined adjuvanted vaccine for induction of antigen-specific T cell
For effective cancer immunotherapy by vaccination, co-delivery of tumour antigens and adjuvants to dendritic cells and subsequent activation of antigen-specific cytotoxic T cells (CTLs) is crucial. In this study, a synthetic long peptide (SLP) harbouring the model CTL epitope SIINFEKL was encapsulated…
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Research
Knowledge on how to adjust a drug dose in special patient populations such as (prematurely born) neonates or children, obese individuals or critically-ill patients, is not only crucial for novel compounds, but also for existing drugs which are often used in an off-label manner in these special patient…
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Babylab
Psycholinguistic research
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Politics: Chinese migration
Chinese organisations increasingly operate across the borders of China, and growing numbers of people from outside China are coming to live there. Professor Frank Pieke believes these movements have a significant effect on central and local government policy in China.
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Pharmacometabolomics; prediction of system-wide multi-biomarker drug response
The lack of success of new CNS drugs in clinical development is in part due to the complexity of the CNS, unexpected side effects, difficulties for drugs to penetrate the brain, but also by the lack of biomarkers.
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Polypept(o)ide-based nanostructures for therapeutic and diagnostic application
Nanoparticles exhibit a number of adjustable properties, e.g., their size, shape, and surface and core chemistry, which can be further diversified with different functional moieties. This opens a broad field for application in diagnostic and therapy. In this respect, the use of a polymeric hybrid material,…
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Minerva in her Study
Following its foundation in 1575, Leiden University was quick to incorporate Roman goddess Minerva in its coat of arms. This explains why Rembrandt’s Minerva from 1635 can be seen on the façade of the Academy Building, which has been in use by the University since 1581. This is where, in the Senate…
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AI in Neuroscience: Development of Methods to make Personalized Predictions for Migraine and Stroke from E-Health Sensor Data
The research of this PhD project can be subdivided into two main disease areas: migraine and stroke. For both we will be investigating how artificial intelligence (AI) and machine learning (ML) techniques can be used to study these afflictions, their (early) detection, and their potential treatment.
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Research
At the division of Biopharmaceutics, we aim to develop and test new therapeutic approaches to limit or even prevent the development of atherosclerosis in order to reduce the number of acute cardiovascular syndromes such as myocardial infarction or stroke.
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Why Things End
Studies on the Decline and Fall of the Amphora Phenomenon
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Tell Ibrahim Awad
Update : August 2017 Dr Willem van Haarlem
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APELAFICO: Acoustic ecology of PELAgic FIsh COmmunities: A study into the effects of construction and operation of wind farms
Do offshore windfarms affect the local biodiversity of the pelagic fish community and are fish deterred or attracted by sounds?
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Guadeloupe
Between 1993 and 2000 the Faculty of Archaeology had a formal cooperation with the Service Régional de l’Archéologie de la Guadeloupe, Direction Regional des Affaires Culturelles (DRAC) and the then director André Delpuech. During that period surveys and excavations were carried out at a number of s…
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Leiden scientists map cell types in fetal kidney
Kidney failure is a serious issue because kidneys cannot regenerate themselves after injury. A possible solution consists of artificially growing healthy kidney tissue. To achieve that, scientists first need to understand kidney development during the earliest stages, in the fetus. Leiden researchers…
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The Netherlands becomes global player organ-on-chip technology
Organ-on-chip technology is used in drug research and customized treatments for patients. Research Institutes and industry join forces within the Institute for human Organ and Disease Model Technologies (hDMT) that was officially launched on May 18. Combining facilities, people and expertise will allow…
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Key publications
Key publications of the Cardiovascular Pharmacology group
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Making the most of the first time a medicine is administered to humans
Collecting as much information as possible about administering a new medicine to people can save a lot of money.
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Research in Africa reduces health spending and prevents diseases of affluence
Health workers have always sought ways to fight disease in vulnerable groups in the population. It is now clear that such research also benefits more prosperous countries. African worm infections and innovative thermometers have shown Leiden researchers how to fight diseases of affluence and keep health…
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Stem cells suppress rejection in organ transplants
Treatment with special stem cells seems to be a good option for suppressing the immune system in organ transplants. Researchers are trying to learn from processes that take place in the human body during pregnancy.
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Computer Science at Leiden University
Leiden Institute of Advanced Computer Science (LIACS)
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Cancer cells: A closer look
What distinguishes a tumour cell from a healthy cell? Researchers are trying to answer this question as precisely as possible. Certain differences could eventually lead to new therapies.
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Applied statistics as a pillar of data science
Data science is now growing fast in many places, but scholars at Leiden University have been developing data science techniques for a long time already. Thanks to their broad-based expertise, Leiden statisticians are currently combining the achievements in statistics with the latest methods of statistical…
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Leiden Institute of Advanced Computer Science
Digital technology is changing academia and society at lightning speed. LIACS is in the midst of this with groundbreaking research into data processing and artificial intelligence (AI). It conducts a unique combination of fundamental and applied research into major issues facing academia and society…
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Key publications
Key publications of the Predictive Pharmacology group.
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Topic: Aging and neuropsychological rehabilitation
Cognitive decline (amongst other problems with attention, concentration, memory) is a common symptom in patients with a variety of brain disorders and has been related to healthy ageing as well. People suffering from cognitive deficits are often significantly hampered in their day-to-day functioning…
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Immune Activation and Tolerance
The Immune Activation and Tolerance group is headed by Dr. Bram Slütter. Vaccination is an experimental, but promising, treatment strategy for atherosclerosis. Previous work has shown that immunization of mice with modified LDL particles can reduce atherosclerotic lesion development, however such vaccines…
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Repair a bad kidney or make a new one to order
Searching for ways to delay the need for a transplant and trying to build kidneys to order.
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Physiological responses to a social-evaluative situation
How is the development of physiological responses to social evaluation in adolescence affected by other normative developments, such as pubertal, socio-cognitive and psychosocial development? Are social anxiety and public speaking anxiety associated with characteristic patterns of stress responses…
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Distracted consumption and compensatory mechanisms
A research into the consumption experience and consumption behaviour.