922 search results for “complex systems” in the Public website
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investigation of the photoprotection mechanism of Light Harvesting Complex II
Solar energy is used by photosynthetic organisms to drive energy required cellular processes. Is absorbed by two groups of pigments, located in the LHCs.
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Fuzzy systems and unsupervised computing: exploration of applications in biology
In this thesis we will explore the use of fuzzy systems theory for applications in bioinformatics.
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Electoral Systems and Turnout: Evidence From a Regression Discontinuity Design
Electoral Systems and Turnout: Evidence From a Regression Discontinuity Design. In this article, published on the website SAGE research methods, authors Jaroslaw Kantorowicz and Tobias M. Hlobil discuss how a Regression Discontinuity Design can be executed.
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Quantitative systems pharmacology modeling of biotherapeutics in oncology
In this thesis, mathematical modeling and simulation was applied as a tool to inform quantitative decision making in oncology drug discovery and development.
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Diederik Meijer
Faculteit Archeologie
d.j.w.meijer@arch.leidenuniv.nl | +31 71 527 2444
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Oxygen Reduction Catalyzed by a Copper(II) Tris(2‐pyridylmethyl)amine Complex through a Stepwise Mechanism
The mechanism of the electrochemical reduction of dioxygen by a mononuclear pyridylalkylamine copper complex was investigated (see picture). It was shown that in neutral aqueous solution dioxygen undergoes stepwise reduction, wherein hydrogen peroxide plays a key role. The rate constants determined…
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The immune system in action against cervical cancer
In the hunt for a vaccine against cervical cancer, fundamental knowledge about the immune system and organic chemistry have been brought together and have already resulted in a vaccine that is now being tested in clinical trials. Scientists are now working hard on an improved variant.
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From molecules to planets: Exploring the chemical heritage of solar systems
Walsh
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Waste Collection Systems Assessed and Good Practices Identified (COLLECTORS)
What is the environmental impact of different waste collection systems across Europe? How can the collection be improved when considering collection, sorting, and treatment, as well as use options for secondary materials?
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Stress-induced modulation of the innate immune system in cardiovascular disease
Promotor: Prof.dr. J. Kuiper
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Liposomes as delivery system for allergen-specific immunotherapy
In this book liposomes are explored as delivery system for allergen-specific immunotherapy. Both cationic and anionic formulations are prepared with Bet v 1, one of the allergens in birch pollen.
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op complexiteit. Onderwijs voor het 'moeras' - Getting a grip on complexity. Education for the 'swamp'
How can pupils and students learn to get a grip on complex 'swamp situations'? Inaugural lecture in abbreviated form held by prof.dr.ir. Fred Janssen on the acceptance of the post of professor of science education at Leiden University on 19 June 2017.
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Integrated omics approaches for systems understanding of adverse outcome pathways
Pathways of toxicity
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Language and the core knowledge system of number
Knowledge and culture subproject 2:
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Resetting the immune system to cure diabetes and rheumatism
In autoimmune diseases such as rheumatism and diabetes the immune system attacks autologous proteins. Leiden researchers are trying to discover how this comes about.
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Geometry and Topology in Active and Driven Systems
The key characteristic of active matter is the motion of an emergent collection (such as a flock of birds), which is driven by the consumption of energy by its active components (i.e. individual birds).
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The interplay between lipids and the immune system in atherosclerosis
Cardiovascular diseases are among the most frequent causes of death in the world. The main underlying pathology of cardiovascular diseases is the development of atherosclerosis in the medium and large-sized arteries.
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Pre-Trial Detention in the Dutch Juvenile Justice System
On 25 January 2018 Yannick van den Brink defended his doctoral thesis titled ‘Voorlopige hechtenis in het Nederlands jeugdstrafrecht’ (‘Pre-trial detention in the Dutch juvenile justice system’). The doctoral research is supervised by Professor Ton Liefaard and Professor Mariëlle Bruning.
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Steady-State Analysis of Large Scale Systems
Promotor: W.Th.F. den Hollander Co-Promotor: F.M. Spieksma
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Sybil-AA: Systems Biology of Alcohol Addiction
The Horizon 2020 project Sybil-AA (Systems Biology of Alcohol Addiction) focuses on modeling and validating disease state networks in human and animal brains for understanding pathophysiology, predicting outcomes and improving therapy in alcohol addiction. Alcohol addiction, the most severe form of…
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Policy Note Insecurity in Burkina Faso – beyond conflict minerals: The complex links between artisanal gold mining and violence
Policy Note Insecurity in Burkina Faso – beyond conflict minerals: The complex links between artisanal gold mining and violence
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Disadvantage and the Legitimation of the System and its Representatives
Does powerlessness and dependence lead to the legitimation of the social, political, and economic status quo and of those in authority?
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Interaction with sound for participatory systems and data sonification
This thesis deals with the use of sound in interactions in the context of participatory systems and data sonification. We investigate an interactive environment where participants perceive information of the data through sound elements.
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WARN-D: developing an early warning system for depression in students
My ERC Starting Grant, funded with €1.5 million for 5 years as part of the Horizon 2020 research and innovation program, is focused on building the early warning system WARN-D to reliably forecast depression in young adults before it occurs. Why depression, and why prediction?
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Bartolomeus Häussling Löwgren
Science
b.j.p.m.haussling.lowgren@cml.leidenuniv.nl | +31 71 527 2727
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Hai Lin
Science
h.x.lin@cml.leidenuniv.nl | +31 71 527 7460
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Oliver Taherzadeh
Science
o.a.taherzadeh@cml.leidenuniv.nl | +31 71 527 2727
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Kristian Rietveld
Science
k.f.d.rietveld@liacs.leidenuniv.nl | +31 71 527 7038
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Suiting Ding
Science
s.t.ding@cml.leidenuniv.nl | +31 71 527 5615
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scanning tunneling microscopy experiments into correlated electron systems
This thesis presents insights from our study of various correlated electron systems with a scanning tunneling microscope (STM). In ordinary metals, electron-electron interactions exist, but get substantially screened due to the sheer number of electrons.
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The urban system in the North Western provinces
The first objective is to create a catalogue raisonée, i.e. a structured database that will store the main attributes of each town in a standardized format database, which will be freely accessible when completed; the second objective is to exploit theories and methods that can help us to understand…
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Systemic Accountability of the European Border and Coast Guard
On 11 November 2021, Mariana Gkliati defended the thesis 'Systemic Accountability of the European Border and Coast Guard'. The doctoral research was supervised by Prof. P. Rodrigues and Prof. L. Besselink (UvA).
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Civil Liability for Damage caused by Global Navigation Satellite System
On 17 December 2018, Dejian Kong defended his thesis 'Civil Liability for Damage caused by Global Navigation Satellite System'. The doctoral research was supervised by Prof. dr. P.M.J. Mendes de Leon.
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Pre-Trial Detention in the Dutch Juvenile Justice System
To what extent is the legislation and use of pre-trial detention of juveniles in the Netherlands in compliance with international children’s rights standards?
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Oegstgeest. A riverine settlement in the early medieval world system
Generations of Leiden students and academics have done archaeological research into the early medieval history of Oegstgeest. This makes this old settlement one of the best-documented sites from that era. In a new book, Leiden researchers take stock.
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SysMedPD: Systems Medicine of Mitochondrial Parkinson's Disease
The overall objective of this project is to identify novel drug candidates that are capable of slowing down the progression of neurodegeneration in the subset of Parkinson’s disease (PD) patients with overt mitochondrial dysfunction. Multimodal phenotypic characterisation of cohorts of monogenic PD…
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The phonological systems of the Mbam languages of Cameroon with a focus on vowels and vowel harmony
The languages of the Mbam-et-Inoubou District of the Centre Region of Cameroon have a unique position in Bantu linguistics. Being in between
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scheduling of cyclo-static dataflow and its application in system-level design
Promotor: Prof.dr. E.F.A. Deprettere, Co-promoter: Todor P. Stefanov
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Digital Humanitarian Networks: Crisis Management as a Social System
Intelligence of the crowd, or in other words, intelligence of a large, random collective, exists mostly in social media platforms such as twitter. The collective does not comprise (at least not necessarily) experts on crises, just regular people mostly. Nevertheless, there is valuable intelligence to…
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Morphodynamic equilibria in tidal inlet systems: sensitivity to geometrical variations
A tidal basin is an inland sea which is almost entirely enclosed by land and connected to the open sea by a tidal inlet. Through the tidal inlets interaction takes place between the tidal basin and the open sea.
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Leiden Complex Networks Network day on 23 September
On Friday 23 September 2016 the Leiden Complex Networks Network day, the LCN2 day, will take place in Leiden.
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Insights from modeling metabolism and amoeboid cell motility in the immune system
This thesis focuses on two processes involved in fighting infections: metabolism and immune cell motility and navigation.
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Fatemeh Mehrafrooz Mayvan
Science
f.mehrafrooz.mayvan@liacs.leidenuniv.nl | +31 71 527 2727
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Teresa Proto
Faculty of Humanities
t.proto@hum.leidenuniv.nl | +31 71 527 2125
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Vivi Rottschäfer
Science
vivi@math.leidenuniv.nl | +31 71 527 7113
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Sander Hille
Science
shille@math.leidenuniv.nl | +31 71 527 7109
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Jennifer Anderson
Science
j.a.anderson@cml.leidenuniv.nl | +31 71 527 2727
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Ben Wielstra
Science
b.m.wielstra@biology.leidenuniv.nl | +31 71 527 5135
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Han de Winde
Science
j.h.de.winde@science.leidenuniv.nl | +31 71 527 1036
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Development of novel analytical technologies for metabolomics and systems pharmacology
We are aiming to develop novel technologies to allow better sample preparation or coupling of analytical methods to (i) analyse ultra small samples, (ii) to analyse more metabolites in a quantitative manner and/or (iii) increase the sample throughput.