2,300 search results for “drug research” in the Public website
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Stefan van der Vorm
Science
s.van.der.vorm@chem.leidenuniv.nl | +31 71 527 4269
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A much-needed new class of antibiotics
Antimicrobial resistance (AMR) is the phenomenon that pathogens become insensitive to the antibiotics that we use against them. A growing number of pathogens is becoming resistant, with methicillin-resistant S. aureus (MRSA) as the most famous example. But while the threat of AMR represents a slow-moving…
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Fluorescence Polarization Activity-Based Protein Profiling on Retaining Glycosidases
Glycosidases are important enzymes in the turnover of polysaccharides and glycoconjugates, and are involved in a range of human pathologies including genetic disorders such as Gaucher and Pompe disease, but also in various cancers.
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New techniques for tuberculosis treatment
About nine million people worldwide contract tuberculosis each year. Research into new treatment for this disease has received fresh stimulus with more efficient techniques and a new understanding of how the tuberculosis bacteria works.
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Why Leiden University?
We are committed to provide you with meaningful, rigorous and quality graduate experiences in a personalized environment with a cutting edge research infrastructure and internationally renowned supervisors.
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Why Leiden University?
We are committed to provide you with meaningful, rigorous and quality graduate experiences in a personalized environment with a cutting edge research infrastructure and internationally renowned supervisors.
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Why Leiden University?
We are committed to provide you with meaningful, rigorous and quality graduate experiences in a personalized environment with a cutting edge research infrastructure and internationally renowned supervisors.
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About Faculty of Science
The Faculty of Science is located at the Leiden Bio Science Park. It was founded more than two centuries ago and currently, more than 8000 people are working and studying at the eight institutes.
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Programme
Everyone is welcome at the Leiden Science Family Day. We have set up a programme with a variety of activities for children, teenagers and adults.
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GRIPonMASH
GRIPonMASH will address the unmet public health need of reducing disease burden and comorbidities associated with Metabolic dysfunction-Associated Steatotic Liver Disease (MASLD).
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Schedule
The Gorlaeus Building will be constructed in three phases, with the new building due to be completed by 2028.
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Master Bio-Pharmaceutical Sciences
This page provides information to support your application for the Master's programme of Bio-Pharmaceutical Sciences.
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Extra-curricular
Are you interested in taking up an extra challenge during your master’s programme? Have you thought about applying for our Summer School programme or are you interested in developing your personal leadership style?
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Extra-curricular
Are you interested in taking up an extra challenge during your master’s programme? Have you thought about applying for our Summer School programme or are you interested in developing your personal leadership style?
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About the programme
BioTherapeutics consists of 120 European Credit Transfer System (EC) points.
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Extra-curricular
Are you interested in taking up an extra challenge during your master’s programme? Have you thought about applying for our Summer School programme or are you interested in developing your personal leadership style?
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About the programme
System Biomedicine and Pharmacology consists of 120 European Credit Transfer System (EC) points.
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Engineering of antigen-saving dissolving microneedles for intradermal vaccine delivery
The intradermal administration route is attractive for vaccine delivery, because of the highly populated antigen-presenting cells in the skin. However, the skin’s main physical barrier, the stratum corneum, prevents vaccines from entering the skin.
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Unlocking Nature’s Pharmacy from Bogland Species
Development of Natural Resource for New Medicines
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Pharmacy
The Pharmacy research group focusses on the development of predictive models to improve clinical drug efficacy and safety. We are moreover strongly involved in the Master specialisation of Pharmacy at Leiden University. We work on clinical problems that require further mechanistic understanding and…
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About the programme
The two-years MSc programme spans the entire spectrum of Analytical BioSciences, Biopharmaceutics, Drug Delivery Technology, Medicinal Chemistry, Pharmacology and Toxicology.
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Fundamental Research in Chemical Biology
Chemical biology research at the Leiden Institute of Chemistry is aimed at understanding biological processes at the molecular level to strengthen the knowledge base of human health and disease. The approach to achieve this goal is a fundamental chemical one; with the aid of chemical probes biological…
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Screening enormous databases to find a cure for cancer
Pharmaceutical research should make more use of data science, says Gerard van Westen, postdoctoral fellow at the Leiden Academic Centre for Drug Research (LACDR). ‘If we want to have better drugs, we should start with data.’
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Science for Society
By carrying out fundamental research and providing excellent education, universities become a breeding ground for innovation and entrepreneurship.
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Vascular and Regenerative Medicine
Methods of treatment for chronic illnesses are limited. Doctors and researchers at Leiden University Medical Center (LUMC) and Leiden University are working on new therapies as an alternative for organ transplants. The goal is to cure the illnesses by restoring organs to their original function. Stem…
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Development of innovative engineered models for viral diseases
A main goal of MSBB research is to address the major bottle-necks in combatting viral diseases: the lack of experimental models that are representative of human pathology and are cost effective and versatile. Viral diseases such as those that cause viral hemorrhagic syndromes or severe acute respiratory…
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Translational pharmacokinetics-pharmacodynamics in zebrafish: integration of experimental and computational methods
The zebrafish is a promising vertebrate model organism in early drug discovery and development.
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Glucocorticoid modulation of the immune response
Glucocorticoids (GCs) are widely prescribed as anti-inflammatory drugs due to their well-established immunosuppressive effects.
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Discovery of FLT3 inhibitors for the treatment of acute myeloid leukemia
The disease acute myeloid leukemia (AML) is characterized by fast progression and low survival rates.
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Upconverting nanovesicles for the activation of ruthenium anti-cancer prodrugs with red light
Promotor: E. Bouwman, Co-promotor: S. Bonnet
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Zebrafish Delivery
Is there a sufficiently large market for drug screening and testing in Zebrafish larvae using membrane fusion?
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European Lead Factory
The European Lead Factory has been created with the ultimate goal to develop lead drug candidates to address neglected diseases including bacterial infections, psychiatric disorders and oncology.
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Coen van Hasselt
Science
coen.vanhasselt@lacdr.leidenuniv.nl | +31 71 527 3266
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Anthe Janssen
Science
a.p.a.janssen@lic.leidenuniv.nl | +31 71 527 4362
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Joost Batenburg
Science
k.j.batenburg@liacs.leidenuniv.nl | +31 71 527 6985
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Roeland van der Rijst
ICLON
rrijst@iclon.leidenuniv.nl | +31 71 527 6496
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Laura Heitman appointed as Professor of Molecular Pharmacology
As of 1 November, Laura Heitman has been appointed full Professor of Molecular Pharmacology at the Leiden Academic Centre for Drug Research (LACDR). Heitman has been working on the understanding and improvement of drug-receptor interactions in early drug discovery. ‘My ultimate aim is to make medicines…
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Diversity Research Cluster
The CADS Research Cluster People, Power and Diversity aims to further theoretical and methodological debates on the classifications of human difference, such as gender, race, ethnicity, sexuality, class, age, ability, religion, level of development, time, etc., and the way these classifications organize…
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Two-pronged attack on infectious diseases
A combination of two potential drugs gives hope of a 'super blockage' of an over-active immune system, Leiden researchers report in Nature. The breakthrough came from the crystallisation of a membrane protein.
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Quantitative systems pharmacology modeling of biotherapeutics in oncology
In this thesis, mathematical modeling and simulation was applied as a tool to inform quantitative decision making in oncology drug discovery and development.
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Quantitative Systems Pharmacology
This research area is focused on the development and application of novel concepts and models in the emerging area of quantitative systems pharmacology (QSP).
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Research in Africa reduces health spending and prevents diseases of affluence
Health workers have always sought ways to fight disease in vulnerable groups in the population. It is now clear that such research also benefits more prosperous countries. African worm infections and innovative thermometers have shown Leiden researchers how to fight diseases of affluence and keep health…
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2024
Elk jaar organiseert het LIBC in samenwerking met de gemeente Leiden een Publieksdag over hersenonderzoek.
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Leiden Medicinal Chemistry researcher Andreas Bender receives prestigious EFMC Prize
Andreas Bender, Assistant Professor for Medicinal Chemistry in the Medicinal Chemistry Division of the Leiden / Amsterdam Center for Drug Research, received the
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Affinity-based profiling of the adenosine receptors
The adenosine receptors are proteins that reside in the extracellular membranes of cells. Activation of adenosine receptors plays a role in many physiological and pathological processes, such as immune responses and cancers.
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Participants
The CIGR comprises research groups from the Institute of Biology Leiden (IBL), the Leiden Institute of Chemistry (LIC), the Leiden Academic Centre for Drug Research (LACDR) and the Leiden Institue of Physics (LION).
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Computational modeling of tumor growth and metastasis and the role of the immune system in tumor destruction
In this project, we aim to obtain a quantitative understanding of the role of the immune system in tumor regression, of the role of tumor cell heterogeneity in cancer growth and of tumor cell migration properties.
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Breakthrough by Leiden researchers in Pompe disease
Researchers at Leiden University have made a breakthrough in the study of the hereditary Pompe disease. Together with colleagues in York, they have developed a molecule that binds to the enzyme that is key to the progress of the disease. The findings have been published in ACS Central Science.
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Systems pharmacology of the endocannabinoid system
In this thesis, a system pharmacology approach, integrating metabolomics, pharmacology and chemical biology, was applied to understand and modulate the endocannabinoid system across different model systems (cells, zebrafish, mice and humans).
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The interplay between lipids and the immune system in atherosclerosis
Cardiovascular diseases are among the most frequent causes of death in the world. The main underlying pathology of cardiovascular diseases is the development of atherosclerosis in the medium and large-sized arteries.