Luca Giomi has the first results of his ERC consolidator grant. He discovered that epithelial cells move collectively but in different ways, depending on the scale you look at. It is hexatic at small scales, and becomes nematic at larger scales: it is a multiscale order. This collective movement of…

Researchers at the Universities of Amsterdam (Uva) and Leiden together with the Netherlands Cancer Institute and Oncode Institute have received a €10,6 million ERC Synergy Grant to develop innovative therapeutic approaches to target glioblastoma. This is a deadly primary brain tumour for which no curing…

Researcher Daan van der Vliet, together with colleagues from the Netherlands Institute for Neuroscience, Leiden University and Utrecht University, has discovered an important mechanism that may be linked to severe cases of multiple sclerosis (MS): the brain contains large numbers of abnormal immune…

At science festival 'Over de kop', surprising brain facts alternate with confronting stories from the operating room. Researchers explain why our brains love beans and why you should never ride a racing bike without a helmet.

Researchers at LUMC have made a breakthrough in understanding PALB2 mutations, an important cause of hereditary breast cancer.

What effect did the lockdown have on young people? Leiden researchers started a study of this in the first year of the covid pandemic. They discovered an impact on the development of the brain areas involved in social behaviour. The researchers published their discovery in Scientific Reports at Nat…

Modified viruses can both kill cancer cells and activate the immune system. This is what an LUMC team discovered while researching a new prostate cancer therapy.

Biological chemist Nathaniel Martin and his team received an NWO grant to examine how blocking a specific enzyme in our body, NNMT, could be helpful in the treatment of some cancers. Trials with mice have been promising, and together with the Netherlands Cancer Institute, Martin wants to take the next…

Women are more often diagnosed with depression, whereas ADHD is much more frequently detected in men. And there are other more striking differences. What role does the brain play in mental health and what is the influence of the environment? For answers to these questions, listen to the ‘(Un)gendered…

Aukje Beers combined theory and practice, as well as chemistry, biology, and computer models. In this way, she discovered two protein inhibitors during her master’s project that could contribute to the development of a new cancer drug. For her research, Beers received the Unilever Research Prize on…

On Sept. 29, Lara Wierenga, together with graphic designer Dirma Janse, presented their new book Atlas of our Brain. In the presence of fellow scientists and other interested parties, they shared some of the stunning illustrations and mind-boggling facts that can be found in the book.

Leiden researchers have developed a groundbreaking model to advance cancer immunotherapy. Using a 3D printer, they create mini-tumors within an environment that closely mimics human tissue. They have also developed a method to monitor real-time interactions of these mini-tumours with immune cells during…

On 11 November Professor of Gastroenterology and Hepatology, Monique van Leerdam will deliver her inaugural lecture entitled, ‘Aiming for Prevention’. Van Leerdam, who specialises in hereditary tumours, was appointed professor in July 2020. In her inaugural lecture she will discuss the importance of…

Leila Akkari was appointed Special Professor of Cancer-immune interactions at the Leiden Institute of Chemistry (LIC) on 15 December. Akkari is a researcher at the Netherlands Cancer Institute (NKI), where she studies the relationship between cancer cells and the immune system, with a particular focus…

Patients with incurable cancer want their oncologist to be clear but to show empathy too. They find hard and vague communication harmful. These are the results of a study by psychologists from Leiden that has been published in the American journal Cancer.

Researchers at the Leiden Institute of Advanced Computer Science (LIACS) are collaborating on the development of a conversation tool for patients with breast, prostate and skin cancer. The aim is to create a conversation tool that can support cancer patients in their care and help them make decisions.…

Few researchers see potential in research on glioblastoma, an incurable brain tumour. Alexander Kros brought together colleagues who are up to the challenge. European research funder ERC recently made 10.6 million euros available, a year earlier NWO provided 3 million euros. ‘In six years, we certainly…

What impact does growing up in a musical environment or during the COVID-19 pandemic have on the brain development of teenagers? This was the focus of psychologist Lina van Drunen’s PhD research, which studied hundreds of twins. Her findings reveal that practising music slows brain development, presenting…

How do you know if a drug will actually work? The Leiden-based spin-off Omivera is developing a new technology that could provide clearer answers. The young company received a seed investment from the investment fund UNIIQ to support its development.

Over a period of seven years, researchers from the International Brain Laboratory mapped 279 brain regions at the cellular level. Their findings are now published in Nature, with both data and software openly shared. Cognitive neuroscientist Anne Urai: 'Any researcher with a good question can make use…

In a new video series for the Corpus Kids Academy, researchers Marieke Bos and Janna Marie Bas-Hoogendam explain how the adolescent brain develops and how anxiety works. 'We wanted to present the information simply, while still preserving the complexity.'

How do fats and enzymes in the brain contribute to multiple sclerosis? In his PhD research, Daan van der Vliet combined chemistry and neuroscience to gain new insights into how brain disorders develop.

In a recent mega-analysis, researchers from Leiden University aimed to clarify the contradictory findings of research into social anxiety disorder. They found that to obtain reliable research results having the largest possible sample size is important. Publication in NeuroImage:Clinical.

For their research many neuropsychologists use the brain scanners at the LUMC. At the start of the pandemic, the rules for visiting the hospital became stricter and a large amount of psychology research looked as though it would fall through. Thanks to good protocols the researchers can now pick up…

Cancer research generates massive amounts of data, but traditional tools often fail to fully harness their potential. How can we unlock this data to provide better treatments for cancer patients? PhD candidate Marina Gorostiola González explored this by using advanced data analysis techniques to guide…

Using mathematics to help children with bone cancer. It sounds a little strange, but for statistician Marta Fiocco, it's just her job. She gets a substantial grant from KiKa for it. With that money, she is going to study the effect of chemotherapy adjustments.

During a well-attended Studium Generale lecture at Rijksmuseum Boerhaave, Professor Ellen de Bruijn demonstrated how hormonal fluctuations influence the female brain. 'We urgently need more attention for the mental health of girls and women during transitional periods.'

Developing a better treatment for patients with head and neck cancer, that is what Binanox, The 2022 iGEM Leiden team, want to achieve. They hope to raise at least 10,000 euros for this cause. Support their crowdfunding campaign today.

Hoping to learn something about the human brain, Leiden researchers are creating a setup to shoot single photons, particles of light, into someone’s eye. ‘The eye is a passageway to the brain.’

Maaike Kempes believes more attention should be paid to non-congenital brain injuries in suspects. This may partly explain their criminal behaviour.

The brain structure of young people with conduct disorder differs significantly from that of their typically developing peers. This is the conclusion of an international study that analysed more than two thousand MRI scans, recently published in The Lancet Psychiatry. Dr Moji Aghajani, one of the principal…

It may seem as though adolescents do as they please, but they are more sensitive to their parents’ opinions than they would appear. The adolescent brain reacts strongly to parental criticism or praise. These are the results of a study by an interdisciplinary research group of psychologists and neuroscientists…

What happens in the brains of people with psychiatric illnesses? With a €23.23 million gravity grant, scientists from different fields will search for biological causes over the next decade. ‘By joining forces, we hope to improve diagnosis and treatment for patients with these diseases.’

Autism, Alzheimer’s, and bipolar disorder: can the development of these mental health conditions be influenced by the ketogenic diet? Increasingly, research suggests it might. 'For those it helps, it can be life-changing,' says neuroscientist Eline Dekeyster.

Why do some people with adverse childhood experiences develop mental health conditions whereas others do not? A Leiden research project is looking for volunteers aged between 18 and 24 to help us understand more about human resilience.

Could we stop cancer cells by cutting off their energy supply? That’s what Dione Blok, a bachelor’s student in Bio-Pharmaceutical Sciences, aimed to find out during her thesis research. She investigated a compound that affects the tumour cells’ energy metabolism. ‘Hopefully, these insights will provide…

Parents appear to be extremely sensitive to feedback they receive about their child. Just how sensitive depends on the (‘rose-tinted’) glasses through which they look at their child. All this can be seen in the brain. Neuroscientist Lisanne van Houtum and her Leiden colleagues published on this issue…

'With this artwork, I want to give the audience a glance into my overstimulated brain and that of other people with autism', says Jasmijn den Hoed. The Faculty of Social and Behavioural Sciences is exhibiting her artwork 'Overstimulated' in the restaurant near the blue wall during Autism Week 25 March…

During adolescence, some young people have stable best-friend relationships, while others change best friends frequently. Developmental psychologist Lisa Schreuders has studied the brains of young adolescents: ‘It seems that friendships in your early years can have consequences for your friendships…

How do cells repair their damaged DNA—and what happens when that process is hindered and cancer arises? Sarah Moser has taken a closer look during her PhD, uncovering surprising insights that could help improve future cancer treatments.

The more data from cancer research we pool, the better we can search for new treatments. But how can we keep patient data safe when sharing it? Leiden researchers will tackle this challenge in a major European project.

Lecture, Tuesday Talk