1,518 search results for “computational biology” in the Public website
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Wessel Kraaij
Science
w.kraaij@liacs.leidenuniv.nl | +31 71 527 5778
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Marcello Bonsangue
Science
m.m.bonsangue@liacs.leidenuniv.nl | +31 71 527 7095
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Knowledge extraction in the quantum random-oracle model
The aim of this thesis is to present novel techniques for proving cryptographic schemes secure against quantum adversaries. Most results are within the context of an idealized model called the ‘quantum random-oracle model’.
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Dirk-Jan Kok
Science
d.d.kok@cml.leidenuniv.nl | +31 71 527 2727
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Karline Janmaat
Faculteit der Sociale Wetenschappen
k.r.l.janmaat@fsw.leidenuniv.nl | +31 71 527 2727
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Michael Richardson
Science
m.k.richardson@biology.leidenuniv.nl | +31 71 527 5215
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Anugrah Anugrah Aditya Budiarsa
Science
a.anugrah.aditya.budiarsa@cml.leidenuniv.nl | +31 71 527 2727
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Jeroen Hubert
Science
j.hubert@biology.leidenuniv.nl | +31 71 527 2727
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Niels van der Windt
Science
n.van.der.windt@cml.leidenuniv.nl | +31 71 527 2727
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Han van Konijnenburg
Science
j.h.a.van.konijnenburg-van.cittert@biology.leidenuniv.nl | +31 71 527 2727
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Madeline Kavanagh
Science
m.e.kavanagh@lic.leidenuniv.nl | +31 71 527 3527
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Chemical tools to study the cannabinoid receptor type 2
The cannabinoid receptor type 2 (CB2R) is associated with several inflammatory diseases with an unmet medical need (e.g. Alzheimers, multiple sclerosis, reumatoid arthritis). Development of new chemical biology strategies to study this protein is essential to aid future development of drugs for these…
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Archaeology thanks to computer-based research
A mix of data research, artificial intelligence and archaeology led to lively discussions on 31 January. On that day the unique event 'AI & Data Science @ Archaeology' took place in which the Data Science Research Programme (DSRP), SAILS and the Faculty of Archaeology joined forces.
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Molecular Physiology
Molecular Physiology is a research group at the Leiden Institute of Chemistry dedicated to the design, synthesis and application of chemical tools to study important biological and biomedical questions. The group is headed by Prof. Dr. Mario van der Stelt and includes the research lines of Assistant…
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A computer made of floppy rubber
A piece of corrugated rubber can function as a simple computer, displaying memory and displaying the ability to count to two. Leiden physicists describe the computing rubber in the journal PNAS. ‘Simple materials can process information, and we want to find the principles behind that.’
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Horizontal gene transfer and spreading of biosynthetic gene clusters and antimicrobial resistance
Biosynthetic gene clusters (BGCs) for natural products are widespread in microbial genomes, and they are rapidly exchanged. This research assesses the factors that control the spread of BGCs and resistance genes in nature. This includes risk assessment for the spread of engineered DNA in nature.
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Molecular Biology for Physics will NOW start on Monday 5 February!
Please note that the course Molecular Biology for Physics will start on Monday 5 February. Please check the schedules for the time and location!
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Interaction with sound for participatory systems and data sonification
This thesis deals with the use of sound in interactions in the context of participatory systems and data sonification. We investigate an interactive environment where participants perceive information of the data through sound elements.
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Synthetic modification of fusogenic coiled-coil peptides
A structural investigation of coiled coil peptides used as membrane fusogens, mimicing naturally occuring coiled-coil fusion proteins. Synthetic modifications have been made to alter lipid attachment, secondary structure and to insert photoactive azobenzene moieties for active control over coiled coil…
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Strategies for braiding and ground state preparation in digital quantum hardware
With the help of quantum mechanics, digital quantum hardware may be able to tackle some of the problems that are too difficult for ordinary computers. But despite these expectations and the ongoing effort of the research community, reliable quantum computers are not yet realized in a lab setting.
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'Biologists also need to be a bit of a data analyst’
Biologists today have to be able to work with big data. Data analysis skills should be taught from the start of the degree programme, or - even better - in secondary school. This is the message of Vera van Noort, new Professor of Computational Biology. Inaugural lecture 22 January.
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Linking the gene regulatory network with the functional physical structure of whole-genome engineered Arabidopsis mutants : an HR-MAS NMR-based
Climate change is a challenge for both current and future generations. New biological resources have to be developed in order to meet the demand for energy as well as the demand for food.
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Archaeology thanks to computer-based research
A mix of data research, artificial intelligence and archaeology led to lively discussions on 31 January. On that day the unique event 'AI & Data Science @ Archaeology' took place in which the Data Science Research Programme (DSRP), SAILS and the Faculty of Archaeology joined forces.
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‘The first quantum computer will fill a sports hall’
The worldwide race to the quantum computer is in full swing. This computer can bring about a breakthrough in discovering medicines and new materials. Leiden researchers, together with the TU Delft, are taking part in the race. There is now a dossier online about their work.
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Quantum computing pioneer Seth Lloyd is the 2019 Lorentz Professor
American physicist and quantum computing pioneer Seth Lloyd is the 65th Lorentz professor. He will deliver the Ehrenfest lecture on 5 June, and several more lectures on quantum computing on 11, 18 and 25 June.
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Master Computer Science in Leiden nr.1 according to Elsevier
Master Computer Science in Leiden nr.1 according to Elsevier
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From Descriptive to Predictive Pharmacology in Children using Semi-Physiological population modelling
An integrated approach of physiological concepts, advanced statistical approaches and large clinical datasets.
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Multi-dimensional feature and data mining
In this thesis we explore machine and deep learning approaches that address keychallenges in high dimensional problem areas and also in improving accuracy in wellknown problems. In high dimensional contexts, we have focused on computational fluid dynamics (CFD) simulations.
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Computer Science: half in Beijing and half in Leiden
Leiden University and the Beijing Institute of Technology will be collaborating in the area of computer science teaching and research. One of the first outcomes of this collaboration will be a joint four-year bachelor's programme. Willem te Beest, Vice-President of the Executive Board, and Professor…
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Topology and Geometry in Chiral Liquids
We study the interplay of topology and geometry with chirality for several passive and active systems, employing both analytical and numerical methods.
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Astrolinguistics
Design of a Linguistic System for Interstellar Communication Based on Logic
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Deep learning for visual understanding
With the dramatic growth of the image data on the web, there is an increasing demand of the algorithms capable of understanding the visual information automatically.
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Leiden University strengthens its focus on Chemical Biology and Medicinal Chemistry with seven new group leaders
Tackling key challenges of Chemical Biology and Medicinal Chemistry to aid drug discovery is one of the focus areas of Leiden University. To this end, the Leiden Early Drug Discovery & Development network (LED3) was established by the Leiden Institute of Chemistry (LIC), the Institute of Biology Leiden…
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Computer science research in Leiden of major relevance to society
An international committee has assessed computer science research at all Dutch universities in the period 2009-2014. For its computer science research, Leiden was awarded the ‘highest’ mark (1) for relevance to society.
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Interfacing the past
Computer applications and quantitative methods in archaeology CAA95.
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Life work award for computer scientist Grzegorz Rozenberg
Leiden prof. emeritus Grzegorz Rozenberg is honoured with the first life time award in formal languages, a research area of theoretical computer science. During a small ceremony at his house, he received a statue that was specially made for the occasion.
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Science
There are eight institutes at the Faculty of Mathematics and Natural Sciences:
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Structural and functional analysis of proteins involved in natural product biosynthesis and morphological differentiation in Streptomyces
Streptomyces present a valuable platform for natural product discovery. Lugdunomycin is a novel angucycline-derived polyketide from Streptomyces sp QL37, with unprecedented skeleton and antimicrobial activity.
- About this minor
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Computer models chart extensive Caribbean inter-island networks
The precolonial inhabitants of the Caribbean islands communicated, travelled, and exchanged objects and ideas along an expansive inter-island network. New methods of computer modeling shed light on these networks. Emma Slayton is set to discuss her work on this topic at her Defense on the 12th of Se…
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Simulating the prehistoric use of fire through computer models
Archaeologists often use the percentages of heat-affected stone or bone artifacts found at archaeological sites as a way to determine how frequently fire was used by the inhabitants. Andrew Sorensen and Fulco Scherjon have come up with a computer model called 'fiReproxies' to simulate how fires used…
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Interactions of nutrients and pesticides and their effects on aquatic macrofauna
Can we distinguish the effects of pesticides from other abiotic and biotic factors that occur in the field? And how do these factors interact with pesticides?
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Towards an effective biodiversity conservation and governance in the Pontocaspian region
Freshwater and brackish water ecosystems are arguably the most vulnerable ecosystems on earth, due to concentrated human developments in and around them. The Pontocaspian (PC) region located at the border of Europe and Asia contains a variety of brackish water ecosystems and unique inhabitants, known…
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Aquatic eDNA: Beyond Species Presence
As a non-invasive genetic method, eDNA based approaches have become an important component of ecologists' and environmental managers' toolkits for biomonitoring in conservation and an increasingly important source of ecological knowledge.
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Erik van Kampen publishes in the Journal of Leukocyte Biology: The effects of poor eating habits persist even after diet
New research published in the Journal of Leukocyte Biology suggests that these changes to the behavior of the immune system are persistent and can continue even after diet is improvedAlmost everyone knows that improving your eating habits will most likely improve your health. What most people may not…
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Article on Affective Computing by Andreas Häuselmann published in IDPL
Affective Computing (AC and sometimes called ‘Emotional AI’) provides opportunities to automatically process emotional data. However, is EU data protection law fit for purpose when it is applied to such AC approaches?
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Granted STW Project: Energy Efficient Computer-Brain Interaction
The STW project Energy Efficient Computer-Brain Interaction (principal investigator for LIACS: dr. T.P. Stefanov) has been granted. Funding for LIACS: 1 PhD student + travel/equipment budget, project duration: 4 years.
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Flat but not shallow. Towards flatter representations in deep semantic parsing for precise and feasible inferencing
Simulating human language understanding on the computer is a great challenge. A way to approach it is to represent natural language meanings in logic, and to use logical provers to determine what does and does not follow from a text. What logic is best to use and how natural language meanings are best…
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Peptide amphiphiles and their use in supramolecular chemistry
Promotor: J.G.E.M.Fraaije, Co-promotor: A. Kros
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Using computer simulations to discover where Neanderthals lived
Archaeologist Fulco Scherjon has used computer simulations to identify where and how Neanderthals lived in West Europe. What stood out was that they probably had lots of children and lived in smaller groups than was previously thought. PhD defence on 28 May.