401 search results for “bacteria” in the Public website
-
White blood cells in transparent embryos
Leiden molecular cell biologists in the research group of Annemarie Meijer have discovered novel early macrophage-specific genes in zebrafish, including a signal transducer pivotal for the migration of macrophages in the innate immune response to bacterial infection. Their findings were published on…
-
Veni grants for eleven Leiden researchers
Eleven Leiden researchers have been awarded a Veni grant by the Dutch Research Council (NWO). The grant will enable them to develop their research ideas for a period of three years.
-
Cum laude physicist Tom O’Brien to research quantum chemistry by quantum computers
With defending his thesis ‘Applications of topology to Weyl semimetals and quantum computing’, the Leiden theoretical physicist Tom O'Brien has gained the rare 'cum laude' qualification. The freshly minted PhD has started a five year research programme on quantum algorithms for quantum chemistry, funded…
-
Vidi research grant for physicist Daniela Kraft
The image of the Leiden microboat traveled all over the world, from the BBC up to Arab shipping blogs. But Daniela Kraft's research group has quite a few more different 3D printed microswimmers up their sleeves. Kraft receives a Vidi research grant for research into these variously shaped active par…
-
Controlling active matter with curvature
Nematic liquid crystals form the key ingredients of most tv screens. The active version of these complex fluids forms a useful model for physicists to research the responses of active matter—like bacteria or traffic flows—to mechanical and geometrical cues. An international research team publishes their…
-
This week the National Antibiotic Development Platform, NADP, was officially launched via a meeting in Utrecht.
Antibiotic resistance is one of the major threats to human health. This week the National Antibiotic Development Platform, NADP, was officially launched via a meeting in Utrecht, with many of the stakeholders in the field present.
-
Media Technology researchers presenting at Brave New World conference
The "BRAVE NEW WORLD" conference is about how future technology will impact human life. On November 8-9 it is held in Leiden. Two of the invited speakers are researchers and lecturers of the Media Technology program.
-
New insights into mycobacterial infections with NWO grant
Why are mycobacteria such successful pathogens? And are there defence mechanisms in the body that help reduce an infection? To find out, Annemarie Meijer has been awarded the NWO Open Competition ENW-XL grant. She will not explore this quest alone. Five other leading Dutch research groups are participating…
-
Free online course teaches you all about imaging
How do you microscopically image zebrafish larvae? The new free online course ‘Imaging the Vertebrate embryo’ teaches you all about it. Leiden PhD candidates Salomé Muñoz Sánchez and Radoslaw Gora contributed to the course.
-
Better insight into competition between microbes
It is mostly rainfall and soil acidity that determine which microbes survive in a particular habitat and which do not. This knowledge is important for maintaining biodiversity. Leiden environmentalists contributed to the research. Publication in Nature on 1 August.
-
Research
The current projects of the Molecular Physiology group focus on proteins of the endocannabinoid system, kinases and antibacterial targets. MSc- and BSc-students can contact Jessica van Krimpen-Kraaijenoord to apply for research internships.
-
Animal sciences and health
In the research theme ‘Animal Sciences and Health’, we work with various animal species to gain insights into fundamental biological processes in both animals and humans.
-
Awards and Grants 2022
An overview of awards and prizes granted to our staff and students in 2022, as well as special appointments at Leiden University and other institutions.
-
Chemical Probe Facility
The Chemical Probe Facility is part of the Leiden Early Drug Discovery & Development (LED3) center. Activity-based protein profiling (ABPP) is one of the pillars of chemical biology. ABPP determines the activity of entire protein families in living cells and tissues under physiological conditions, such…
-
Bio-organic Synthesis
The research in the Biosyn group is focused on the design, synthesis and function of the four major types of biomolecules: nucleic acids, carbohydrates, peptides and lipids and hybrid structures thereof. These biomolecules and their derivatives are used in drug discovery and chemical biology, to develop…
-
The skeleton as a source of information
Bones contain information about people’s lives such as where they came from, their age at death and which diseases they suffered from. Researchers can deduce a lot from them about a person’s life and about human evolution. This generates leads that could help solve present-day problems, such as how…
-
Hit and Lead Optimization
The goal of hit and lead optimization is to optimize suitable chemical starting points that can modulate a drug target. The methods and technologies used are similar to those in Hit Discovery, but once the compound has shown activity in an animal model, it moves from 'hit' to 'lead.'
-
Marcellus Ubbink receives grant for research into evolution of enzymes
The Dutch organisation for scientific research NWO has announced that it will award an ENW-Klein grant to Marcellus Ubbink (LIC) for his research into the role of temperature in the evolution of enzymes. Sixteen grants have been awarded in total.
-
AI research in Zuid-Holland: three examples
How designers are even more creative with a robot in their team, how Twitter could predict the stock market, and how to catch a single bacterium in the act of infecting a cell. Artificial intelligence has penetrated every corner of science in Zuid-Holland. Three researchers from Delft University of…
-
Discoverer of the Year, Best Dissertation and Education prize 2015
During the Faculty of Science New Year's reception, Daniël Rozen was named Discoverer of the year 2015. Nienke van der Marel and Koen van der Maaden both won the prize for the best dissertation and Jeroen van Smeden was named Best Teacher of 2015.
-
A lifeline for Leiden research – TB solution a step closer thanks to this Indonesian university
Herman Spaink knows of many substances that may help combat tuberculosis. Lab space to study them safely is very limited in Leiden. A brand-new lab at Universitas Gadjah Mada in Indonesia will soon provide a solution. About time, says Spaink, ‘The disease is on the rise and is becoming less sensitive…
-
How our single-celled relatives package their DNA
A group of single-celled organisms organises its DNA in a similar way to higher organisms such as plants, animals, and fungi. However, the way packaged DNA is read out differs between the two related groups, Bram Henneman discovered. PhD defence on 5 December.
-
‘Look beyond your own discipline’
Good research means looking beyond disciplinary boundaries, said Professor of Molecular and Cellular Biochemistry Remus Dame in his inaugural lecture on 10 May. Processes that take place on DNA shouldn’t only be researched in a test tube but also in living cells, for instance.
-
Niko Tinbergen lecture 2019: Stem cells, mini organs and eternal life
Three speakers, three fascinating science stories and a well-filled lecture hall. The Niko Tinbergen Lecture had a successful restart on 10 December 2019.
-
Combating antibiotic resistance together
Antibiotic resistance is a common problem among patients. The European Project TIPAT trains pharmacologists, microbiologists and immunologists of six universities in interdisciplinary thinking. The ultimate goal is to develop better treatment guidelines to combat resistance. Coen van Hasselt of the…
-
NWO-XS grants for two innovative research projects
Two Leiden Science researchers received an NWO-XS grant for their research. Both projects are highly promising, but also high-risk. Macrophages that trap bacteria and data storage made from 2D materials convinced the board of their potential.
-
Polluted water as a source of fertilizer
It may well be possible to remove nitrate from polluted groundwater and at the same time produce ammonia in a sustainable way, according to PhD candidate Phebe van Langevelde and Professor Marc Koper of the Leiden Institute of Chemistry in Joule on 26 January. Together with a German colleague, they…
-
Caterpillars listen to voicemail by eating soil
Leaf-eating caterpillars greatly enrich their intestinal flora by eating soil. Even effects of plants that previously grew in that soil can be found back in bacteria and fungi in caterpillars. Researchers from the Netherlands Institute of Ecology (NIOO-KNAW) and Leiden University write about this discovery…
-
New insights into chemical sensing of the human pathogen for cholera
The bacterium Vibrio cholerae is a serious threat to our health because it is the causative agent of cholera. Worldwide, over a billion people per year are at risk of cholera infection. New strains of V. cholerae are resistant to the multiple drugs used to treat cholera, meaning that new types of drugs…
-
The evolutionary added value of sex
Asexual procreation in female wasps leads to an accumulation of genetic mutations, and the shrivelling of their sex organ. Leiden biologist Ken Kraaijeveld published this discovery in Evolution. His research is one of the first experimental studies into the consequences of asexual procreation.
-
Something for everyone at Leiden's Night of Arts and Science
Come to the Night of Arts and Science in Leiden 's historic city centre on 17 September. You can enjoy music, interactive experiments, theatrical plays, lectures, modern dance, comedy and much, much more. Many of the activities are in English.
-
Daniela Kraft appointed professor of Experimental Physics
Daniela Kraft and her research are a familiar fixture at the Leiden Institute of Physics (LION). Both have been awarded fellowships, grants and frequent media coverage. Effective July 1, Kraft has been appointed professor of Experimental physics, particularly in soft and biological matter.
-
Mapping of bacterial genomes to combat infectious diseases
Mapping of bacterial genomes to combat infectious diseases
-
Oort Lecturer 2018: James Kasting about the search for life on planets around other stars
If there is life outside our galaxy, how could we find it? In his Oort Lecture, James Kasting talks about his search for simple life on other planets. Kasting was in the Netherlands for two weeks, because he was invited as the Oort Professor 2018.
-
Cancer pathogenesis and therapy
With cancer, a person’s body cells grow uncontrollably. Putting together a detailed picture of how this comes about makes it possible to develop efficient therapies. Researchers at the Leiden University Medical Centre (LUMC) and Leiden University are working together to gain a better understanding…
-
Publications
Relevant publications of the CIGR participants.
- Lectures
-
Leiden biologist receives National Zoology Award
Maurijn van der Zee, evolutionary biologist at the IBL, received the National Zoology Award for his research on the evolutionary success of the insects. The award was handed out last Saturday, the 17th of December, by Professor Jan Kammenga, chairman of the Royal Dutch Zoological society.
-
Macrophages as drivers of an opportunistic infection
The opportunistic bacterium Burkholderia cenocepacia is feared by cystic fibrosis patients and is emerging in hospital-acquired infections. An international study sheds new light on the infection mechanism of this opportunistic pathogen that may have large implications for treatment strategies.
-
“Principles of Plant-Microbe Interactions”
Emeritus Professor Ben Lugtenberg edited a book on “Principles of Plant-Microbe Interactions” together with Paul Hooykaas, Eddy van der Meijden and Jos Raaijmakers, all from the IBL.
-
Proteins and DNA loops: Science-Groot grant for Remus Dame
How do our cells keep DNA stored away? To find out, biochemist Remus Dame received a 3 million euro Science-Groot grant. Leiden University will share the grant with TU Delft, VU Amsterdam and the Hubrecht Institute.
-
What Darwin couldn’t see: Expedition to uncover invisible life in Galápagos
An international research team is to search for invisible life in the Galápagos Islands. The diversity of bacteria and other microscopic organisms may not be evident to the naked eye, but it is essential to nature. To the islands' giant daisies, for instance: unique endemic plants that are currently…
-
PhD candidates deserve special attention: their new confidential counsellor Annemarie Meijer explains why
She studied biology in Leiden and never left. Now, as Professor of Immunobiology, Annemarie Meijer has taken on the role of the new confidential counsell for for PhD candidates. It's a role that suits her perfectly: she has extensive experience in the research world and has guided dozens of PhD candidates.…
-
Veni grants for 16 Leiden researchers
Sixteen researchers at Leiden University are to receive a Veni grant from the Netherlands Organisation for Scientific Research (NWO). These awards offer promising young researchers the opportunity to further develop their own ideas over a period of three years.
-
Using gold particles to make the invisible visible
Gold nanoparticles give us a better understanding of enzymes and other molecules. Biswajit Pradhan, PhD candidate at the Leiden Institute of Physics, uses gold nanorods to study individual molecules that would be challenging to detect otherwise. Resulting knowledge can be applied to many research fields,…
-
How oak seedlings teach us more on dune restoration
What is the best way to restore dune ecosystems? The project TERRA-Dunes researches the role of soil microbes in the development of natural dune areas. Recently, the project went into a new phase: planting 412 oak seedlings grown in different type of soils.
-
Photosynthesis works with valves
Photosynthesis is the origin of life on earth, but it is a phenomenon that is still barely understood. Take, for example, the extremely efficient mechanism of electron transport. Leiden researchers demonstrate for the first time where one particular cause of this might be found.
-
Steering the immune system with liposomes
Liposomes – nano-sized spheres composed of fatty molecules – are very promising for vaccination. Bio-pharmaceutical scientist Naomi Benne discovered that the immune response in animal models can be steered by varying the charge of the liposomes. She obtained her PhD degree on 8 September for this research,…
-
Paco Barona Gomez ready to work in Leiden: ‘Fundamental research creates opportunities’
Paco Barona Gomez is the newest associate professor at the Institute of Biology Leiden (IBL). The Mexican researcher is fascinated by the evolution of natural products: compounds made by microbes, but also plants and animals. ‘It’s like we investigate chemical dark matter.’
-
Aphid genome unravelled
Leiden evolutionary biologist Maurijn van der Zee has co-operated on an enormous international project to describe the genetic material of the pea aphid Acyrthosiphon pisum. The more than 100 authors involved in the project have published their findings in the online magazine PLoS Biology.