87 search results for “adp rol” in the Public website
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Synthetic Study on ADP-ribosylation
This Thesis focuses on the design and synthesis of ADP-ribosylated compounds that can be applied in biological studies.
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Synthesis of ADP-ribose Analogues
Since the global COVID-19 pandemic, the coronavirus responsible (SARS-CoV-2) has been extensively probed for promising protein targets to establish drug-based therapies.
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Puzzling pyrophosphates: synthetic methodologies for ADP-ribosylated biopolymers
This thesis focuses on developing new chemical synthesis strategies to produce native ADP‑ribosylated biomolecules with precise structural control.
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Synthetic Methodology Towards ADP-Ribosylation Related Molecular Tools
Phosphorylation affects all four major biomolecules – proteins, lipids, carbohydrates and nucleic acids – and plays a pivotal role in the most fundamental cellular functions.
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Synthetic Affinity-Based Probes for ADP-Ribose Interactome Studies
Adenosine diphosphate ribosylation (ADP-ribosylation) is a fascinating post-translational modification (PTM) that plays a role in a variety of cellular processes and is associated with several diseases, including cancer and viral infections.
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Synthetic peptides, nucleic acids and molecular probes to study ADP-Ribosylation
This thesis presents the first synthetic peptides ADP-ribosylated on serine, threonine, tyrosine, arginine and cysteine.
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Synthesis of well-defined ADP-Ribosylated biomolecules
Promotor: G. A. van der Marel, Co-promotor: D. V. Filippov
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Research project NET-ROL
The NET-ROL project builds on the EU's definition of the rule of law to investigate the role of networks in law-making, executive decision-making, and the judiciary. It examines how these networks influence the weakening of the rule of law. Through an interdisciplinary perspective, the project explores…
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Veranderend kunstenaarschap - De rol en betekenis van de kunstenaar in participatieve kunstpraktijken
De positie van kunst en kunstenaars in de westerse samenleving
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The development of molecular tools for investigating NAD+ metabolism and signalling
Nicotinamide adenine dinucleotide (NAD+) is the substrate used for the introduction of the ubiquitous and highly dynamic PTM in which either one or multiple adenosine diphosphate ribose (ADPr) moieties are covalently attached to a nucleophilic side chain of an specific amino acid in the target protein…
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Sven Wijngaardens.wijngaarden@lic.leidenuniv.nl | 071 5272727
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De rol van de curator bij de aanpak van onregelmatigheden (NL)
This publication is in Dutch. Please consult the Dutch page.
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How protein modifications cooperate to repair DNA
How do protein modifications work together to repair DNA, and what can we learn about these interactions to better understand disease?
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'Fiscaliteit speelt rol bij vertrek DSM uit Nederland'
Na Shell en Unilever is DSM het derde grote bedrijf dat vertrekt uit Nederland. Fiscalisten zijn niet verbaasd: het sentiment over het vestigingsklimaat hier is momenteel minder gunstig.
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Eerste Kamer vervult te veel een politieke rol
De rol van de Eerste Kamer is het toetsen van wetten op uitvoerbaarheid. Wim Voermans, hoogleraar Staatsrecht, zegt voor NPO Radio1 dat de Eerste Kamer nu te veel een politieke rol in plaats van een controlerende rol vervult.
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Eric De Brabandere over rol EU in kwestie rond Westelijke Sahara
Marokko zegt het contact met de Duitse regering op. Volgens Marokkaanse media is ministeries en andere overheidsinstanties per brief gevraagd direct de samenwerking op te schorten met de Duitse ambassade in Marokko.
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Dissertations
The E.M. Meijers Book Series is the book series published by the E.M. Meijers Institute of the Leiden Law School. The series includes dissertations defended by PhD candidates from the Leiden Law School. Below you will find recent dissertations of team members of the Business & Law Research Network.
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The Manichaeans of Kellis: Religion, Community, and Everyday Life
Mattias Brand defended his thesis on 10 April 2019
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Islamophobia and Securitisation: The Dutch Case
This book examines how Muslim communities in the Netherlands perceive and experience extremism, counter-radicalisation policies, and Islamophobia.
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Gaining control of lipid-based nanomedicine by understanding the nano-bio interface
Dit proefschrift beschrijft een collectie aan alternatieve strategieën voor het begrijpen, ontwerpen en toepassen van lipide nanosystemen, waarin de rol van de bio-nano interacties centraal staan. In het bijzonder wordt gekeken naar de interactie van RNA-lipide nanosystemen, bekend van de toepassing…
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Maar zo bedoelde ik het niet!
Aan de hand van bekende en minder bekende voorbeelden uit de wereld van politiek en media laat dit boek zien hoe je strategisch gebruik én misbruik kunt maken van taal.
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Elementaire deeltjes. Kunstgeschiedenis
Een nieuw boek in de reeks Elementaire deeltjes
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A recipe for desert: analysis of an extended Klausmeier model
Promotores: Arjen Doelman, Jens Rademacher, Max Rietkerk
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PhD Research
Doctoral research at Leiden Law School means research at the highest level.
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Small molecule inhibitors of Nicotinamide N-Methyltransferase (NNMT)
NNMT wordt beschouwd als een nieuw potentieel farmacologisch doelwit in de behandeling van een verscheidenheid van kankers, stofwisselingsziekten en andere pathologieën. Het toenemend aantal publicaties waarin de rol van NNMT bij ziekten wordt opgehelderd, heeft op zijn beurt de ontwikkeling van krachtige…
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Other books
Below you will find a collection of books, other than those in the BLRN book series, to which members of BLRN have contributed.
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Research
Combining different disciplines, researchers work together to formulate innovative solutions to societal problems.
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Dynastic Juniors in Europe and Asia
Subproject of
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Return to sender: a multi-method study of guardianship against transnational sexual exploitation of children
On 22 June, Anneke Koning defended the thesis 'Return to sender: a multi-method study of guardianship against transnational sexual exploitation of children'. The doctoral research was supervised by Joanne van der Leun, Masja van Meeteren and Johan van Wilsem.
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Research Group Diplomacy and Global Affairs
The research group on Diplomacy and Global Affairs studies international diplomacy, international organisation, global, transnational, multi-level and comparative governance.
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Towards a comprehensive understanding of (facilitating) teacher professional development
What are ‘missing links’ in research on teacher professional development trajectories? We focus on the role and development of teacher facilitators in designing and implementing (collaborative) professional development trajectories.
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The scientists behind LED3
Meet the scientists within the LED3 community
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Klimaatstrafrecht: De rol van het strafrecht binnen het juridische antwoord op klimaatverandering
PhD defence
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Archaeology of Europe
In the master’s programme in Archaeology, you can follow courses on the archaeology of Europe, deepening your understanding of the continent’s long history.
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Life in Custody Study (LIC)
The Life in Custody (LIC) Study comprises a large-scale research project into prison climate and the quality of prison life in Dutch prisons.
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Leidse handboeken
Recente publicaties in de Leidse handboekenreeks zullen hieronder verschijnen.
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Institute of Security and Global Affairs
The Institute of Security and Global Affairs (ISGA) in The Hague offers bachelor’s and master’s programmes, minors, and research in security studies, covering cybersecurity, terrorism, diplomacy and contemporary security challenges. Focus keywords: ISGA, bachelor, master, minors, research, security…
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Irregularities in the vicinity of insolvency
Every year, more than three thousand businesses are declared insolvent in the Netherlands. The purpose of bankruptcy is to divide the assets of these companies among the creditors. However, the value of the claims of the creditors often exceed the value of the assets of the company
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Ellen de Bruijn: In the media
Stay tuned for updates on relevant media appearances of Ellen de Bruijn.
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Julia Cramer Group - Quantum and Society
The research group ‘Quantum and Society’ explores the boundary between quantum technology and science communication.
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Bestraffing
Leids onderzoek naar bestraffing komt tot stand uit verschillende disciplines. Het onderzoeksproject kent een juridische, criminologische, sociaalwetenschappelijke en filosofische invalshoek.
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Gineke Wiggers receives prize for paper on User-Focused Ranking in Legal Information Retrieval
PhD student Gineke Wiggers has won the 2nd prize for her paper on User-Focused Ranking in Legal Information Retrieval in the PhD consortium of the 31st International Conference on Legal Knowledge and Information Systems (JURIX).
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Publications
ELS@Leiden research encompasses a wide range of empirical-legal projects carried out within Leiden Law School from the perspective of multiple disciplines and methods. Here you can find the publications of our (former) lab members since the start of the Sector Plan.
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Hoven in Holland, 900-1300
In welke mate hebben domaniale structuren de machtsvorming en nederzettingsontwikkeling in en van het gewest Holland bepaald?
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Professor Joke Bouwstra elected as KNAW member
Professor Joke Bouwstra has been elected as member of the Koninklijke Akademie van Wetenschappen (KNAW, The Royal Dutch Academy of Sciences). This is a very prestigious recognition and a great honor for Joke. You can find the announcement by the KNAW below (short version) and as an attachment.
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Health Governance
Growing health inequalities, rising healthcare costs, an ageing population, and shortages of healthcare staff are just some of the challenges facing healthcare, both in the Netherlands and beyond. These issues transcend the boundaries of the medical sector and touch on broader themes such as social…
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Imams in Western Europe. Developments, Transformations, and Institutional Challenges
Bij Amsterdam University Press verschijnt 'Imams in Western Europe. Developments, Transformations and Institutional Challenges' onder redactie van Mohammed Hashas, Jan Jaap de Ruiter en Niels Valdemar Vinding, een publicatie waarin tal van zaken met betrekking tot imams in Europa behandeld worden. De…
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Evaluatie Wet homologatie onderhands akkoord
In juli 2024 is het boek 'Evaluatie Wet homologatie onderhands akkoord' uitgebracht. Het boek bevat het rapport van het evaluatieonderzoek van de Wet homologatie onderhands akkoord (WHOA) uitgevoerd door een onderzoeksteam van de Rijksuniversiteit Groningen en de Universiteit Leiden in opdracht van…
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Leiden Law Cast #1: Child benefits scandal & compassion with Professor A.G. Castermans
Leiden Law Cast is a podcast made by Leiden Law School, Leiden University, for everyone who wants to learn more about current legal issues.
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Media about hundreds of thousands of unknown galaxies
An international team of more than 200 astronomers from 18 countries has published hundreds of thousands of unknown galaxies. The data are part of a project lead by Leiden professor of Observational cosmology Huub Röttgering. Both Dutch and international media reported extensively about the publica…