999 search results for “complex systems” in the Public website
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Systems pharmacology of the amyloid cascade
According to the amyloid cascade hypothesis, accumulation of beta-amyloid (Aβ) peptides initiates the pathological cascade in Alzheimer's disease (AD).
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Concurrent Systems
In modern information systems, a large number of different components are often active simultaneously. This phenomenon - known as concurrency - underlies not only the functioning of computer systems but of any system in which many processes take place at the same time.
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Topological decoding of biomolecular fold complexity
Biological polymers, including proteins and the genome, undergo folding processes crucial for their proper functioning. Even slight changes in the folding structure of these biopolymers can have significant implications, leading to the development of various pathological conditions, such as neurodegenerative…
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NWO grant for optimal design of complex and distributed cyber-physical systems
NWO awarded a grant for novel research on Complex and Distributed Cyber-Physical Systems (CPS). The grant will fund a four-year research project in which they hope to devise a method to explore and find optimal designs for CPS. Todor Stefanov, Associate Professor at the Leiden Institute of Advanced…
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Systems Pharmacology
The aim of the research programme Systems Pharmacology lies in the development of personalised medicine strategies, and development of new systems-based approaches in translational and clinical pharmacology.
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Systems and security
Researchers at LIACS are working to devise the computers of tomorrow that will be the backbone of the Cloud and Edge computing paradigms as well as the Internet of Things. In this respect, we are involved in research and development of high performance computing systems, embedded & real-time computing…
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Systems & infrastructure
Here are some systems and infrastructures that are useful to students.
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Accelerating the Photocatalytic Water Splitting in Catalyst−Dye Complexes
As a virtually inexhaustible source, solar energy plays a major role in future global energy scenarios.
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Hidden Complexities of the Frankish Castle
Social Aspects of Space in the Configurational Architecture of Frankish Castles in the Holy Land, 1099-1291
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Iron complexes as electrocatalysts for the water oxidation reaction
In this dissertation, the synthesis and characterization of a series of iron complexes based on different ligand platforms are described.
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The Saint-Servatius complex in Maastricht
The Vrijthof excavations (1969-1970)
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Charge transport properties of Ru-complex molecules: the influence of humidity
I will give a general introduction to the field of molecular electronics, its history, methods and challenges. I will also introduce the subject of my investigation and provide a brief outlook to the remainder of our thesis.
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Targeting the adenosinergic system
Adenosine is an endogenous ligand which exerts its action by activating adenosine receptors (ARs), while its circulating levels are controlled via a variety of mechanism and proteins, amongst others the equilibrative nucleoside transporters (ENTs).
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Quantitative Systems Pharmacology
This research area is focused on the development and application of novel concepts and models in the emerging area of quantitative systems pharmacology (QSP).
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Ennis & Blarel, The South Asia to Gulf Migration Governance Complex
The Gulf is a major global destination for migrant workers, with a majority of these workers coming from South Asia. In this book, a team of international contributors examine the often-overlooked complex governance of this migration corridor. Going beyond state-centric analysis, the contributors present…
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Distance-based analysis of dynamical systems and time series by optimal transport
Promotor: S.M. Verduyn Lunel
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addition reactions in interstellar ice - new pathways towards molecular complexity in space -
Promotor: Prof.dr. H.V.J. Linnartz, Co-Promotores: S. Ioppolo, H.M. Cuppen
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Education system
Every year, Leiden University welcomes some 27,000 students from 115 different countries. In educating these students, we are committed to ensuring that the quality of our tuition meets or exceeds the highest-possible standards.
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Marc Spijker
Science
spijker@math.leidenuniv.nl | +31 71 527 2727
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Onno van Gaans
Science
vangaans@math.leidenuniv.nl | +31 71 527 7122
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Hermen Jan Hupkes
Science
hhupkes@math.leidenuniv.nl | +31 71 527 5587
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Marcel de Jeu
Science
mdejeu@math.leidenuniv.nl | +31 71 527 7118
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Arjen Doelman
Science
doelman@math.leidenuniv.nl | +31 71 527 7123
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Analysis of Energy Systems
The Institute of Environmental Sciences has carried out and participates in several projects that deal with the analysis of energy systems.
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Modulation of the immune system for treatment of atherosclerosis
Cardiovascular diseases are the primary cause of death in the world with atherosclerosis as primary underlying cause.
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System Verification Lab (SVL)
The correctness of computational systems is of great importance to our society, since it becomes ever more reliant on the benefits of computing.
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ELIXIR Systems Biology Community
Making systems biology modelling a central pillar of research in biology
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Analysis and Dynamical Systems
The research of our group is centered around dynamical systems, functional analysis and their interplay.
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1,2-cis-glycosylations: method development and synthesis of complex oligosaccharides
Promotor: G.A. van der Marel, Co-promotor: D.C. Codée
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Patterns in natural systems
Promotor: A. Doelman, Co-promotores: P.J.A. van Heijster; A. Zagaris
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Leiden study system
Students in Leiden are entitled to good teaching and good supervision. For their part, there are some conditions they have to meet to ensure that they complete their studies within the time allotted.
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Biomimetic redox reactions of the Cu(II) μ-thiolate complex
Promotor: Prof.dr. E. Bouwman
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Oxidation catalysis on Pt and Au: complexity of simple chemistry
Promotor: J.W.M. Frenken Co-Promotores: I.M.N. Groot; L.B.F. Juurlink
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Inextricable ties between chemical complexity and dynamics of embedded protostellar regions
Promotor: E. F. van Dishoeck, Co-promotor: C. Walsh
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Analysis and Dynamical Systems
The research of this programme is centered around dynamical systems, functional analysis, and their interplay.
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LU-Card support centre WSD-complex (Lipsius)
Lipsius, Cleveringaplaats 1, 2311 BD, Leiden
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Martina Chirilus-Bruckner
Science
m.chirilus-bruckner@math.leidenuniv.nl | +31 71 527 4837
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Advanced Computing and Systems (MSc)
The master's specialisation Bioinformatics at Leiden University focuses on research, development and application of computational tools and approaches for expanding the use of biological, medical, behavioral and health data.
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The structure of the cytochrome P450cam-putidaredoxin complex determined by paramagnetic NMR spectroscopy and crystallography
Promotor: Prof.dr. M. Ubbink
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Statistical learning for complex data to enable precision medicine strategies
Explaining treatment response variability between and within patients can support treatment and dosing optimization, to improve treatment of individual patients.
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Systems Biomedicine and Pharmacology (MSc)
The two-years master’s specialisation System Biomedicine and Pharmacology at Leiden university focuses on predicting drug response with computational modelling, developing individualised therapies, and developing innovative analytical tools for personalised health strategies.
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Pulses in singularly perturbed reaction-diffusion systems
Promotor: Arjen Doelman, Co-promotor: Vivi Rottschäfer
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Measures and Matching for Number Systems
This thesis provides explicit expressions for the density functions of absolutely continuous invariant measures for general families of interval maps, that include random maps and infinite measure transformations, not necessarily number systems.
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Interaction between legal systems
Interaction between Legal Systems acknowledges that law-making and law enforcement are increasingly taking place on various levels: in a global context, in EU context, on a national level and in a private law framework. These levels influence each other, sometimes directly, on the basis of a hierarchical…
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Control theory methods for quantitative systems pharmacology models
Following their application to system biological models, control theory techniques have further potential to aid in the understanding and application of quantitative systems pharmacology models.
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Evolutionary traps – Balanced lethal systems
How do balanced lethal systems originate and persist in nature?
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Systems diagnosis of chronic diseases, explored by metabolomics and ultra-weak photon emission
Promotor: J. van der Greef; Co-promotor: E. van Wijk, M. Wang
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Nano-scale electronic structure of strongly correlated electron systems
In condensed matter systems electron-electron interactions, negligible in everyday metals, can dramatically alter the electronic behavior of the system. Examples of such altered behavior include high-temperature superconductivity and modulation of the electron density.
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Development of organ-on-a-chip systems for translational and personalized medicine
We have developed a microfluidic platform for complex 3D organotypic cell cultures (so-called organ-on-a-chip systems) which are suited for integration in 96 or higher well plate format.