2,653 search results for “heart and vascular disease” in the Public website
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Cardiovascular Pharmacology
The Cardiovascular Pharmacology research group headed by Ilze Bot aims to elucidate the mechanisms that underlie atherosclerotic plaque destabilization, which is the key process that leads to acute cardiovascular syndromes such as a myocardial infarction or stroke.
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Political Religion Beyond Totalitarianism
The eleven innovative essays in this volume explore the notion that all forms of modern mass politics, including liberal democracies, need such a form of sacralization of politics to function.
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Noonan and LEOPARD syndrome in zebrafish: molecular mechanisms and cardiac development
Promotor: Prof.dr. J. den Hertog
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Layers of dental tartar
Bacteria in the teeth tell us a lot about nutrition and disease in our ancestors. It also tells us more about the immune system. This provides clues for treating modern diseases and allergies. For a long time archaeologists were irritated by tartar on the teeth of excavated skulls. They thought that…
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Vision and Mission
The need for novel drugs as well as innovations in their development and application is as urgent as ever. Below we present our vision , mission, and our key research areas.
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LIFES: From Reusable Data to New Treatments and Faster Diagnoses
Early diagnosis, new treatments, and personalised care: all of these are possible if we can better unlock the wealth of information hidden in health data. Unfortunately, this data is often poorly organised, difficult to access, and not interoperable. The new international Leiden Institute for FAIR and…
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Cancer pathogenesis and therapy
With cancer, a person’s body cells grow uncontrollably. Putting together a detailed picture of how this comes about makes it possible to develop efficient therapies. Researchers at the Leiden University Medical Centre (LUMC) and Leiden University are working together to gain a better understanding…
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ERC Consolidator Grants for four Leiden researchers
From fake news via WhatsApp to mini hearts from a 3D printer: four Leiden researchers have been awarded a Consolidator Grant by the European Research Council. These grants, of up to 2m euros, enable researchers to establish or expand their research team and continue to develop their career.
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A quick call with Nadine Akkerman about the Annie Romein-Verschoor Lecture: ‘I feel a connection with Annie’
Each year on or around International Women’s Day, the university hosts the Annie Romein-Verschoor Lecture. You are welcome to attend − even if you wouldn't call yourself a feminist, says professor and organiser Nadine Akkerman. ‘You get the best discussions with a diverse audience.’
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Targeting Inter-Organ Cross-Talk in Cardiometabolic Diseases
PhD defence
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5 Vidis for Leiden researchers
Of the 87 Vidi research subsidies awarded by NWO, five have been awarded to Leiden researchers. This represents almost 6 per cent of the successful applications.
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Leiden researchers join forces against tuberculosis
About one and a half million people worldwide die each year from tuberculosis. For thirty years, therapy with antibiotics has been the same, while it takes far too long and can lead to resistant pathogens. Leiden researchers from four institutes are now joining forces to develop more effective and efficient…
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VICI grants for five Leiden researchers
Research organisation NWO has awarded a VICI grant to five Leiden researchers. In total, 32 leading researchers in the Netherlands have been awarded a VICI grant.
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Dangerous microbes in lower level safety lab? A new technique could make it possible
Researchers need to work in specialized environments when they work with dangerous bacteria and viruses. These microbes spread easily, so only in labs with a high biosafety levels they can be studied. Unfortunately, to look at the microbes properly, expensive microscopes are needed that are not always…
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Live long and healthy
Leiden University will be 444 years old this year and is still very much alive and kicking. But how can we humans grow old healthily? Hanno Pijl at LUMC is the grand master of lifestyle medicine. He explains how we can all benefit from a sensible - but still enjoyable - lifestyle.
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NWO awards curiosity-driven research Ariane Briegel with grant
Professor of Ultrastructural Biology Ariane Briegel has received a grant in the NWO Open Competition Domain Science in the XS category. This grant emphatically encourages curiosity-driven and bold research with a maximum of 50,000 euros.
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Research lines
Current research at the Skin Barrier and Vaccination group.
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Drugs for our immune system in the right place at the right time
Immunologist Leender Trouw specialises in the complement system, which is part of the immune system. In some diseases drugs help activate or inhibit this system. This is best done ‘in the right place at the right time’ − the title of his inaugural lecture.
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26 million for research into the impact of non-genetic factors on health
Who will be affected by certain chronic diseases, and who will not? For 30 percent that depends on heredity factors, whereas no less than seventy percent is explained by external factors. A Dutch research consortium receives 18 million euros from the prestigious Zwaartekrachtsubsidies to study these…
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Osteoarchaeologist Maia Casna receives the NVFA Incentive Prize: ‘I try to push osteology into the public eye as much as I can’
PhD candidate Maia Casna received an Incentive Prize from the Dutch Association for Physical Anthropology (NVFA). She was rewarded this honor for her innovative research into respiratory diseases and her talent for presenting her results to both academic and general audiences. ‘It feels really nice…
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Better vaccines against malaria and tuberculosis
The infectious diseases malaria and tuberculosis are responsible for 2.1 million deaths every year. Leiden researchers are currently testing a new tuberculosis vaccine.
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Global Public Health (BSc Major of Liberal Arts and Sciences: Global Challenges)
Although the world has made tremendous progress in health, education, sanitation and hygiene, global public health challenges still exist. Disparities in health exist between and within nations as evidenced by inequalities in disease burden, mortality, nutrition and environmental well-being. How does…
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Growth and development of actinomycetes
We aim to provide new insights relating to the spectacular multi-cellular life cycle of streptomycetes and other actinobacteria.
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Versatile SNP genotyping
The SNP genotyping line offers flexible genotyping for small and large projects at affordable price and high quality. The use as SNPs as molecular markers is very versatile and can be used for a wide variety of scientific questions ranging from paternity analysis, conservatuion genetis towards QTL…
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Inkomen en afkomst zijn risicofactoren bij kans op hart- en vaatziekten
Nederlanders met lage inkomens lopen tot 1,5 keer meer risico op het krijgen van een hartaanval of beroerte dan rijkere landgenoten. Bij Surinaamse Hindoestanen is dit risico 1,9 keer hoger. Dat blijkt uit onderzoek van het LUMC en het HagaZiekenhuis. Nederlandse artsen kijken tot nu toe niet naar deze…
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Contact
Leiden Law School is located in two beautifully renovated national monuments in the historic heart of Leiden. The Law School also has teaching and research facilities at its campus in The Hague.
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On the Emergence of the Energy Transition
The energy system is at the heart of two of the greatest challenges of the 21st century: decreasing CO2 emissions to meet the ambitions of the Paris agreement while fulfilling the growing energy demand associated with the economic aspirations of a growing world population.
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Exploratory Data Mining in Multimodal data
The change from a closed institution to an open living environment for patients with late stages of dementia will give the patients more freedom in their day-to-day life. The effect of this change on the patients’ mobility, activity and interaction with others will be assessed with sensor technology…
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Academia in Motion
Would you like Leiden University to be a more open workplace that recognizes and rewards all contributions, and an institution that creates and shares knowledge more freely with society?
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Research
At the division of Biopharmaceutics, we aim to develop and test new therapeutic approaches to limit or even prevent the development of atherosclerosis in order to reduce the number of acute cardiovascular syndromes such as myocardial infarction or stroke.
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Research
The research carried out within the unit Health, Medical and Neuropsychology investigates the psychological factors of health and disease, and the development of innovative treatment.
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Development and evaluation of evidence based self-help and online programs for people with a somatic stressor and depressive symptoms
What is the effectiveness of (booklet or online) self-help programmes for people with somatic stressors and depressive symptoms? What works best for whom? How to improve motivation and adherence?
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Imaging the prenatal brain in congenital heart defects
PhD defence
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Imaging and Bioinformatics
On the basis of the characteristic aspects of a picture, certain computers can tell us what the picture is showing. They can learn this in the same way that young children are able to learn to recognize images. Further improving these techniques opens the way to a whole range of new applications. Biology…
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Skin Barrier and Vaccination
The Skin Barrier and Vaccination group is led by Prof. Joke Bouwstra. One of the key functions of the skin is its barrier function, which is located in the uppermost layer of the skin, the stratum corneum. The stratum corneum consists of enucleated dead cells (corneocytes) embedded in a lipid matrix.…
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Education
The Faculty of Archaeology at Leiden University offers education in Human Osteoarchaeology. We offer a second-year Bachelor course in Human Osteoarchaeology and an extensive one-year track in the Master’s in Archaeological Science specialisation, resulting in a Master of Science degree after complet…
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Serge Rombouts: 'AI is learning from brain scans and helping find a diagnosis'
Serge Rombouts is a physicist whose PhD thesis was about functional MRI (fMRI). This visualises activity in regions of the brain. The appealing images of glowing brain regions that emerge from the computer are the result of calculations. According to Rombouts, this isn’t proper artificial intelligence.…
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Research
The chemical industry must continue to innovate for a more sustainable, healthier society. The reseachers from the Leiden Institute of Chemistry (LIC) contribute by applying their knowledge to themes such as sustainability, energy and health.
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Partners
Our research programme collaborates with all kinds of partners to achieve our goal: bringing scientific discoveries to the clinic as soon as possible.
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Unwiring beneficial functions and regulatory networks in the plant endosphere
How do plants lure microscopically small 'support teams' into their roots for protection against diseases? And what functions are activated in the microbes and the plants?
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Quantitative Systems Pharmacology
This research area is focused on the development and application of novel concepts and models in the emerging area of quantitative systems pharmacology (QSP).
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Kinetic profiling of positive allosteric modulators of the mGlu2 receptor
Supervisor: Maarten Doornbos
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AI in Neuroscience: Development of Methods to make Personalized Predictions for Migraine and Stroke from E-Health Sensor Data
The research of this PhD project can be subdivided into two main disease areas: migraine and stroke. For both we will be investigating how artificial intelligence (AI) and machine learning (ML) techniques can be used to study these afflictions, their (early) detection, and their potential treatment.
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Clinical and Health Psychology (research) (MSc)
The research master’s specialisation Clinical and Health Psychology prepares you for a PhD trajectory.
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NWO grant gives way to more sustainable production of antibiotics
The opportunity to explore a new, exciting research topic. That is how Lennart Schada von Borzyskowski describes his successful application for the NWO XS grant. It comprises 50,000 euros, which the researcher from the Institute of Biology Leiden (IBL) will spend on investigating a more sustainable…
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Discovery Leiden nominated for KIJK: Best Tech-idea of 2021
Using artificial intelligence to find new antibiotics. With that, researchers from Leiden University are nominated by magazine KIJK for the Best Tech-idea of 2021. From September 14 onwards people can vote to crown one of the nominees as the winner.
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Ultrasensitive in situ visualization of active glucocerebrosidase molecules
Deficiency of glucocerebrosidase (GBA) underlies Gaucher disease, a common lysosomal storage disorder. Carriership for Gaucher disease has recently been identified as major risk for parkinsonism. Presently, no method exists to visualize active GBA molecules in situ. We here report the design, synthesis…
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Personalized Medicine
Assessing and implementing new diagnostics strategies for stratifying patients
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B cell modulation in atherosclerosis
Cardiovascular disease is a major global burden and atherosclerosis is the main underlying pathological process.