3,288 search results for “design” in the Public website
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Pharmacology based toxicity assessment: towards quantitative risk prediction in humans
Promotor: Prof.dr. M. Danhof, Co-promotor: O.E. Della Pasqua
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Plant BioDynamics Laboratory
The Plant BioDynamics Lab (PBDL) is a laboratory dedicated to experiments designed to develop and validate quantitative mathematical models of dynamical processes in biology. The principal objective of developing these models is to make quantitative predictions about these processes.
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Custom-made language training
The form and content of the course are determined by your answers on the intake form and, if necessary, an intake interview.
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Emotion regulation in young children with autism
Children with autism spectrum disorder experience serious challenges in social functioning, which threatens their development in many areas of functioning.
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Algorithms for analyzing and mining real-world graphs
Promotor: Prof.dr. J.N. Kok, Co-Promotor: W.A. Kosters
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Mission and Vision of ACPA
ACPA brings art practices and academic research together in a programme that enhances both cutting-edge practice and blue-sky research.
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Education highlights
These aspects make the Media Technology MSc program unique:
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Chaotic dynamics in N-body systems
Promotor: Prof.dr. S.F. Portegies Zwart, Co-promotor: D.C. Heggie
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Biological, Soft and Complex Systems
We study the physics of a broad range of biological and soft materials
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A European Ministry of Finance?
On 21 October 2021, Frederik Behre defended the thesis 'A European Ministry of Finance?'. The doctoral research was supervised by Prof. S.C.G. Van den Bogaert.
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Visualizing strongly-correlated electrons with a novel scanning tunneling microscope
Materials with strongly correlated electrons show some of the most mysterious and exotic phases of quantum matter, such as unconventional superconductivity, quantum criticality and strange metal phase.
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Terror and the Legitimation of Violence: A Cross-National Analysis on the Relationship between Terrorism and Homicide Rates
This article written by Marieke Liem & Alexander Kamprad investigates the relationship between terrorism and interpersonal violence. They conducted cross-national analyses on the effects of terrorism mortality rates on homicide rates. Results showed that terrorism appears to be robustly and positively…
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LUCRIS/GSM Graduate School Management
The Graduate School Management (GSM) module is a registration and monitoring system for PhD candidates and their supervisors. All information is stored uniformly and made accessible in one place. The GSM module is part of the LUCRIS system. Converis is the software behind LUCRIS.
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Optimal decision-making under constraints and uncertainty
We present an extensive study of methods for exactly solving stochastic constraint (optimisation) problems (SCPs) in network analysis. These problems are prevalent in science, governance and industry.
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Strategy
The division of BioTherapeutics consists of the former divisions Biopharmaceutics and Drug Delivery Technology.
- Leiden Institute of Advanced Computer Science
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Evaluation of (4-Arylpiperidin-1-yl)cyclopentanecarboxamides As High-Affinity and Long-Residence-Time Antagonists for the CCR2 Receptor
Animal models suggest that the chemokine ligand 2/CC-chemokine receptor 2 (CCL2/CCR2) axis plays an important role in the development of inflammatory diseases. However, CCR2 antagonists have failed in clinical trials because of a lack of efficacy.
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European Lead Factory
The European Lead Factory has been created with the ultimate goal to develop lead drug candidates to address neglected diseases including bacterial infections, psychiatric disorders and oncology.
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Iron complexes as electrocatalysts for the water oxidation reaction
In this dissertation, the synthesis and characterization of a series of iron complexes based on different ligand platforms are described.
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The ins and outs of ligand binding to CCR2
Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: Dr. L.H. Heitman
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Tools and Data
Tools and Data of the department of Environmental Biology
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City Gates in the Roman West: Forms and functions
This publication by Cornelis van Tilburg, will be published at Sidestone Press on September 28, 2022. It discusses various aspects of city gates in the Western Roman Empire: Italy, Spain, Gaul, Germany and Britain.
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Transforming Innovations in Africa
The authors in this volume explore how external innovations (products, technologies, services, institutions and processes) have been appropriated in African societies in order to be acceptable and relevant to local conditions, expectations and demands.
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Gorlaeus Bicycle Storage
Currently, the construction is underway for a large, covered bicycle parking facility with space for nearly 3000 bicycles. In the summer of 2024, the Gorlaeus bicycle parking will be ready for use.
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Leiden Learning & Innovation Centre
LLInC supports innovative and high-quality education, within Leiden University and in partnership with academic and social organisations.
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Intellectual Property Law
The IP Law (Intellectual Property Law) department provides education and conducts research in the field of intellectual property law.
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Hysterons and pathways in mechanical metamaterials
Mechanical metamaterials are carefully engineered materials whose properties are controlled by their structure, not by their composition, which allows using metamaterials to study and control physical effects in detail.
- Leiden Leadership Centre
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Framing international cooperation: citizen support for cooperation with the European Union in Eastern Europe
This article studies the influence of framing on preferences for cooperation with the EU.
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Opportunity and Problem in Context (OPiC). A framework for environmental management in developing countries
Promotor: W.T. de Groot
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On the efficacy of digitized storybooks for young learners with attention problems
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Research
The programme group Research Methods and Statistics offers support to researchers from a variety of research projects within Education and Child Studies.
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On the geometry of fracture and frustration
Promotor: Prof.dr. M.L. van Hecke, Co-Promotor: Prof. dr. V. Vitelli
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TARGETBIO: Transmission of Antimicrobial Resistance Genes and Engineered DNA from Transgenic Biosystems in Nature
This project aims to assess the risk of spread of antimicrobial resistance genes in the environment derived from currently used synthetic biology approaches in the field of drug discovery.
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LUCRIS/Converis Graduate School Management module
The Graduate School Management (GSM) module is a registration and monitoring module for you and your supervisor(s). All information is stored in a uniform way and made accessible in one place. Converis is the software behind LUCRIS.
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Teacher professional learning and collaboration in secondary schools
This dissertation focuses on teacher professional learning and collaboration in secondary schools.
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Utility Spots, Science Policy, Knowledge Transfer and the Politics of Proximity
How we think about and act on the usefulness of scientific research has epistemological and political implications: what knowledge consists of, how it comes about and to what ends. In this dissertation, I situate the usefulness of scientific research in concrete places for knowledge exchange. The exchange…
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Benchmarking Discrete Optimization Heuristics
This thesis involves three topics: benchmarking discrete optimization algorithms, empirical analyses of evolutionary computation, and automatic algorithm configuration.
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Stakeholder engagement as a conduit for regulatory legitimacy?
Stakeholder engagement practices are on the rise in regulatory governance. This raises an important question regarding implications for regulatory legitimacy. Engagement mechanisms are not by default legitimizing: Even when initiated to tap into an array of ‘benevolent’ desiderata, unless carefully…
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Development of kinase inhibitors and activity-based probes
Promotor: H.S. Overkleeft, J. Neefjes, Co-promotor: M. van der Stelt
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A landscape biography of the 'Land of Drumlins': Vooremaa, East Estonia
In the contemporary myriad of definitions and approaches of landscape, the starting points and limits of the concept of landscape biography are being explored, but also tested in this thesis. What exactly is a landscape biography? What does it constitute of? Is landscape biography just a narration of…
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Systems Pharmacology
The aim of the research programme Systems Pharmacology lies in the development of personalised medicine strategies, and development of new systems-based approaches in translational and clinical pharmacology.
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Sparsity-Based Algorithms for Inverse Problems
Inverse problems are problems where we want to estimate the values of certain parameters of a system given observations of the system. Such problems occur in several areas of science and engineering. Inverse problems are often ill-posed, which means that the observations of the system do not uniquely…
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Strategic Partnerships/ Cooperation Partnerships
Erasmus+ Strategic Partnerships (Key Action 2) are transnational projects designed to develop and share innovative practices and promote cooperation, peer learning, and exchanges of experiences in the fields of education, training, and youth. There are two kinds of Strategic Partnership; those supporting…
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Using synthetic control method to estimate the growth effects of economic liberalisation: Evidence from transition economies
Jaroslaw Kantorowicz and Rok Spruk examine the contribution of institutional reforms to economic growth.
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Vaccination against atherosclerosis; induction of protective CD8 T-cells through immunization
Atherosclerosis, in particular rupture of atherosclerotic plaques, is the underlying cause of most heart attacks or strokes and is the leading cause of death worldwide.
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Acknowledgements and contributors
Rembrandt & Leiden University: The Bigger Picture commemorates the 444th anniversary of Leiden University and the 2019 Rembrandt Year. Our special thanks go to Germanisches Nationalmuseum (Nuremberg), The Leiden Collection (New York), Museum De Lakenhal (Leiden), Mauritshuis (The Hague), Rijksmuseum/Musée…
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Learning tools
It is our goal to deliver a convenient, enjoyable, learning experience that goes beyond the basics. All of the apps are an initiative of the HANDS! Lab for Sign Languages and Deaf Studies at Leiden University, as part of the Language Socialization in Deaf Families project funded by the Leiden University…
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In vitro and in vivo evaluation of synergistic and opposing effects of Chinese herbal medicine and natural compounds on immuno-modulation.
Can we link multiple components from herbal extracts with their biological activities?
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Global Perspectives on the Bretton Woods Conference and the Post-War World Order
The historiography of the Bretton Woods conference of July 1944 is dominated by the personal clash between the principal negotiators, Harry Dexter White of the United States and John Maynard Keynes of Britain.