756 search results for “immunity infection and tol” in the Public website
-
Nose of E. coli zips open and shut
PhD student Wen Yang discovered how certain cell receptors in E. coli bacteria signal 'smells'. With the use of ice-cold electron microscopy microbiologists from Leiden gain more insight into how bacteria respond to their environment. Publication in mBio.
-
Translating science into treatments of rare metabolic disorders
Leiden biotech startup Azafaros has successfully completed a funding round, raising 25 million euros of investments for developing treatments of rare metabolic disorders. The company holds exclusive license to a library of novel patented compounds discovered by experts from Leiden University.
-
My favourite spot: one for the coffee lovers
'This one is really for the coffee lovers out there, but tea drinkers and co. need not tune out because this spot has got more to offer than just coffee.' Rachel Quennell, student of International Studies in The Hague, is a mine of information for lovers of good coffee.
-
Flu stops when you block the enzyme that cleaves off virus particles
A flu virus could cause a pandemic. And then we would be poorly armed because flu viruses are starting to become resistant to flu medications like Tamiflu. Chemist Merijn Vriends successfully worked on an improved version of such medications. He will be awarded his doctorate on September 12th.
-
How to determine medication dosages for premature babies
Premature babies almost always require treatment with medication. Doctors usually determine the dosages based on data from children who were not born prematurely, while preterm infants often develop differently. Medication researcher Aline Engbers investigated three commonly used drugs, focusing on…
-
Master student Maddalena Centanni awarded with Arenberg-Coimbra Group Prize
Former masterstudent Bio-Pharmaceutical Sciences Maddalena Centanni will be awarded the 2020 Arenberg Coimbra Prize for Erasmus Students. Centanni spent her six month Erasmus exchange at Uppsala Universiy in Sweden where she looked for ways to improve anti-cancer drug dosing.
-
Student team hopes to heal skin with squid protein
Eleven ambitious Leiden students hope to heal burns with a special substance from squid teeth. They are taking part in the international iGEM competition. They need to raise almost 10,000 euros to fund their project this summer.
-
How a pathogenic bacterium searches for food
Bacteria whirl around in the mouths of most people, forming dental plaques and sometimes causing nasty gum infections. Treponema denticola might be a dangerous pathogen, but not much is known about this bacterium. It was up to Ariane Briegel and her research group to change that.
-
Status update in the evolutionary race between humans and resistant bacteria: two steps forward for us
A patent for what may be a potent, new antibiotic. And: a clear overview of promising approaches to overcome a crucial resistance tactic employed by bacteria. In the span of one week, two researchers from Leiden are receiving their PhDs, each of them on an important step in the battle against bacteria…
-
Career College: To PhD or not to PhD?
Career and apply for jobs
- International seminar: “Indonesian Heritage and Library Collections”
-
ERC Starting Grants for five young Leiden researchers
Five researchers from Leiden University have been awarded a Starting Grant by the European Research Council (ERC). This grant of on average 1.5m euros enables researchers who show potential to start their own project, lead a research team and implement their best ideas.
-
Restoring and constructing organs
Physicians and researchers of the Leiden University Medical Center (LUMC) and Leiden University are working on therapies for restoring damaged organs such as hearts and kidneys. They are even trying to construct tailor-made organs. Read more on this topic in the new science dossier on Vascular and Regenerative…
-
ERC Consolidator Grants for four Leiden researchers
From fake news via WhatsApp to mini hearts from a 3D printer: four Leiden researchers have been awarded a Consolidator Grant by the European Research Council. These grants, of up to 2m euros, enable researchers to establish or expand their research team and continue to develop their career.
-
Seventeen million for Dutch X-omics Initiative
The Dutch X-omics Initiative has received seventeen million euros from NWO as part of the National Roadmap for Large-Scale Infrastructure. Leiden University’s metabolomics research led by Thomas Hankemeier is one of the participators.
-
Tailored medicines
Medicines do not follow the one size fits all principle, because genetic differences can influence their efficiency. That is what research by PhD candidate Julia Hillger shows. She defends her PhD dissertation Take it Personal on Thursday 7 December.
-
Health psychologist Jos Brosschot professor by special appointment
Jos F. Brosschot has been appointed as a professor by special appointment on the chair ‘psychophysiological mechanisms of stress in daily life’. This chair has been created by the Foundation for Research into Psychosocial Stress.
-
PhD Graduate Van Groesen: ‘Nothing is too crazy to try.’
In a world where bacteria are increasingly resistant to antibiotics, Emma van Groesen set out to find a solution. This month she obtained her PhD, after four years of research into new variants of the antibiotic vancomycin. With success.
-
Do placebos help against itching?
If a pill containing no active ingredients still helps, this positive expectation is called a placebo effect. A negative expectation is called a nocebo effect. Both can be produced by verbal suggestions and conditioning. According to Andrea Evers’ research group, combining these is the most promising…
-
Tracing cancer with a simple blood test
Thanks in part to the persistence of a Leiden research group, cancer could be detected in the near future with just a single drop of blood. Not only can the diagnosis be determined at an earlier stage, but the blood test is also cheap, fast and patient friendly. The first results of this method seem…
-
Caterpillars listen to voicemail by eating soil
Leaf-eating caterpillars greatly enrich their intestinal flora by eating soil. Even effects of plants that previously grew in that soil can be found back in bacteria and fungi in caterpillars. Researchers from the Netherlands Institute of Ecology (NIOO-KNAW) and Leiden University write about this discovery…
-
€8.5m for research into healthy ageing and vitality
A large multidisciplinary team of experts on ageing has secured over €8.5m for a major study of which factors and solutions promote healthy ageing and increase vitality. The LUMC and the Leiden Academic Centre for Drug Research (LACDR) are two of the centres involved in this national research projec…
-
Preventing heart attacks by earlier detection of cardiovascular disease
In the Netherlands, 1.55 million people suffer from cardiovascular diseases. Yet, acute cardiovascular events, such as a heart attack or stroke, often occur unexpectedly. That is because many people do not know they are at risk for such an event. Immunological researcher Amanda Foks and her colleagues…
-
These are the seven Veni winners of the Faculty of Science
The Faculty of Science has received no less than seven Veni grants this year. Camila Correa, Max van Duijn, Stéphanie van der Pas, Sergii Pud, Mónica Varela Álvarez, Joseph Callingham, and Melissa McClure will receive a maximum of 250,000 euros to further develop their own research ideas over a three-year…
-
'Dear Leader’ – but not really
On 8 May, the memoirs of Jang Jin-sung are appearing worldwide under the title Dear Leader. Jan Jin-sung was a member of the personal circle of the former North Korean leader, Kim Jong Il. Dear Leader provides a radically different perspective on the workings of the regime, as it reveals the moving…
-
Bacteria without cell wall gobble up DNA from environment
A bacterium hiding from the immune system and picking up bits of DNA from its environment. The result: gaining new traits, such as better protection against antibiotics. Fortunately, we have not found such a damning scenario yet. However, PhD student Renée Kapteijn did find the first clues, which…
-
Treatment before patients develop rheumatism provides lasting relief
Early treatment benefits patients who have not fully developed rheumatoid arthritis but are in the preliminary stages of the disease. This is what researchers from the Leiden University Medical Centre (LUMC) have reported in The Lancet. Patients in the pre-arthritis stage who were temporarily prescribed…
-
Pain relief without the high
Researchers at Leiden University led by Mario van der Stelt (Leiden Institute for Chemistry) have set ‘gold standards’ for developing new painkillers based on the medicinal effects of cannabis. Publication in Nature Communications.
-
Ensnaring tumours in their own web
Erik Danen is looking at how to inhibit tumours that do not respond well to medicine – and he is making some headway. The Professor of Cancer Drug Target Discovery studies the interaction between tumour cells and their surroundings. Inaugural lecture on Friday 10 May.
-
LCN2 Seminar February 2023
Lecture
-
Improving immunotherapy for melanoma: models, biomarkers and regulatory T cells
PhD defence
-
Structural biochemistry of the pentraxins
PhD defence
-
CRB1 gene therapy coming of age: Mechanistic insight and rAAV assays on mouse & human retinal organoid models
PhD defence
-
Detection of schistosome circulating antigens CCA and CAA
PhD defence
-
Improving Nature’s Antibiotics to Overcome Resistant Bacteria
Lecture, NGL-lezing
-
Rembrandt made a mess of his legal and financial life
‘Rembrandt was a stubborn, socially inept shopaholic.’ In his lifetime the Dutch master became embroiled in over 20 legal disputes. Emeritus Professor of Private Law Bob Wessels has written a book about Rembrandt’s legal and financial dealings.
- IBL Symposium 2022
-
Book Reviews
The Hague Journal of Diplomacy regularly publishes reviews of recent books within the field of diplomacy and global affairs.
-
FAQ research with animals
Antwoord op veelgestelde vragen over onderzoek met proefdieren bij de Universiteit Leiden. FAQ
-
Discoverer of the Year, Best Dissertation and Education prize 2015
During the Faculty of Science New Year's reception, Daniël Rozen was named Discoverer of the year 2015. Nienke van der Marel and Koen van der Maaden both won the prize for the best dissertation and Jeroen van Smeden was named Best Teacher of 2015.
-
More efficient drug development with the help of computer models
The coronavirus has the world in its grip. Finding a cure has never been more important. Unfortunately, the development of new drugs for treatment of the COVID-19 disease caused by the virus and development of a vaccine are complex, lengthy, and above all costly processes. With the help of computer…
-
Urgent research projects funded by LUF
Misleading graphs, the erosion of democracy and the weakening of bones as a side-effect of medication. Researchers are starting work on these very topical problems, funded by subsidies from the Leiden University Fund awarded on 12 October.
-
New professor of Theoretical Physics: ‘The problems I study can come from anywhere in society’
The financial sector, supply chains and ecology. Not necessarily topics you might associate with physics, yet it’s exactly what new professor Diego Garlaschelli is dealing with. The common thread? Complex networks.
-
Astronaut André Kuipers touches down at Leiden University
In his guest lecture on 22 January André Kuipers took school pupils and students on trip through space. His mission was to interest his young listeners in science and technology.
-
Phenomix Field Lab offers promising healthcare solutions
In the Phenomix Medical Delta Field Lab, which was officially opened on Thursday 9 July, scientists, healthcare institutions and businesses work together to develop innovative applications in the field of metabolomics. This research field makes it possible to determine which drugs will be effective…
-
‘Girls can be hackers too’
How safe are the dozens of apps on our phone? And how do we make sure organisations don’t get hacked? Cybersecurity expert Olga Gadyatskaya works on all these kind of security issues. Next to that, she hopes to inspire young girls to consider a career in cybersecurity. ‘Too many young women think: I’m…
-
Big data on a small scale
Mirjam van Reisen favours big data built up from local inputs in developing countries and suitable for local use. The new Professor of Computing for Society at Leiden's Faculty of Science connects data science with development sociology. Inaugural lecture 10 March.
-
Three Leiden Science projects receive computing time on national supercomputers
A night sky of more than 40 petabytes in size, simulating young star clusters and understanding how the body inhibits viruses: three Leiden projects have received computing time on one of the national computer systems.
-
Teaching Prize nominations are now in
Every year, an outstanding lecturer receives the Faculty Teaching Prize from the teaching committee. The prize is awarded during the official opening of the academic year on 7 September. This year, students nominated eight candidates.
-
Caught in living cells: how bacteria regulate their genes to defend themselves
For the first time, it was shown in living cells how the bacterium E. coli regulates genes that help it survive in a new environment. Biochemist Fatema Zahra Rashid managed to do this using a technique she fine-tuned. Her research into changes in 3-dimensional chromosome structure offers clues for ways…