2,553 search results for “design” in the Public website
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Corpora Non Agunt Nisi Fixata: Ligand Receptor Binding Kinetics in G Protein-Coupled Receptors
The present thesis focuses on the pharmacological concept of drug-target interaction, which dates back to the beginning of modern pharmacology.
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From data to models: reducing uncertainty in benefit risk assessment: application to chronic iron overload in children
M. Danhof, Co-promotor: O.E. Della Pasqua
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Overview
Our research is aimed at a smoother and speedier transition from preclinical research to pharmacological interventions, and the delivery of drugs in the human body by use of small molecules and biologics.
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Sustaining the unsustainable? The political sustainability of pensions in Finland and the Netherlands
What makes a pension scheme sustainable? Most answers to this question have revolved around expert assessments of pension schemes’ affordability or adequacy. This study shifts focus from the financial or social sustainability of pension scheme designs to their political sustainability. The key question…
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Services
CWTS B.V. is a company affiliated to CWTS and owned by Leiden University. Our core mission is to contribute to a sustainable science system by providing high-quality services for research evaluation, research management and science policy. These services are based on analyses and visualizations of academic…
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First Steps for Teachers and Facilities
Getting started with active learning & teaching can be as simple as assessing on what is already accomplished. Here are some practical courses of action to begin experimenting with active learning, whether you are a teacher or responsible for the spaces.
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Mapping for meaning. Using concept maps to integrate clinical and basic sciences in medical education
In which way and to which extent is integration articulated in concept maps and which factors affect the resulting concept maps? By which factors is the perceived usefulness of such concept maps affected?
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Collaboration
Our AI researchers work closely with other institutions such as Delft University of Technology and Erasmus University.
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Considering to apply?
Media Technology: a master’s program for you?
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The Founder of Bon, the Birth of a Myth
In this dissertation, the life account is constructed of of the founder of Bon Religion, Shenrab Miwo.
- Integration in Urban planning
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The Social History of Labor in the Iranian Oil Industry
This dissertation studies the formation of the wage laboring class in the Iranian oil industry during the first decades of the 20th century.
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The recognition process of youth with problematic anxiety in general practice
Do general practitioners recognize children with or at risk of problematic anxiety and is there a pattern that might help differentiate those with and without anxiety disorders in general practice?
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Making Matters. Collective Material Practices in Critical Times
The NWO-funded research project Critical Making engages with practices that cross the disciplinary boundaries of art, design, engineering and technological making, and (artistic) social intervention.
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ELS Academy PhD Kick-off Event
PhD Kick-off Event
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Does feedback targeting text comprehension trigger the use of reading strategies or changes in readers' attitudes? A meta-analysis
Our previous meta-analysis (Swart et al., 2019) had shown that feedback targeting text comprehension given when students perform a reading task positively influences learning from text. So far, differences in the effects of feedback were explained by design features, such as the timing and richness…
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Security Vision
How do technologies of computer vision, which promise to replace humans in the understanding of images, work in practice in the field of security, and what are their ethical and political implications?
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Shape Analysis for Phenotype Characterisation from High-throughput Imaging
We have studied shape with a particular focus on the zebrafish model system. The shape is an essential appearance of the phenotype of a biological specimen and it can be used to read out a current state or response or to study gene expression.
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Natural Computing
Research in the natural computing cluster covers theoretical foundations, the development of new algorithms, and interdisciplinary applications of natural computing methods.
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Are Leadership Preferences Gendered?
This article examines the consequences of stereotypical beliefs regarding gender, traits, and leadership styles for manager preferences.
- Colophon
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Mechanical metamaterials: nonlinear beams and excess zero modes
Mechanical metamaterials are man-made materials which derive their unusual properties from their structure rather than their composition.
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Education
Religious Studies at Leiden University allows you to study a broad spectrum of religions and their manifestations.
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Empirical signatures of universality, hierarchy and clustering in culture
In this thesis,
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Research
The members of LUXs develop and validate new methods and algorithms for analysing data, and apply these in a wide range of problems. Their research ranges from multidisciplinary applications to proving mathematical theorems.
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The Public Dimension of International Investment Law and Arbitration
How can international investment law and arbitration take account of the public interest in, and more broadly, the public dimension of, the relations between foreign investors and host States ?
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Learn to Dare!
The ‘Leer te Durven!’ program (Learn to Dare) is a preventive training program for children with mild anxiety symptoms (Simon & Bögels, 2014). The program has been developed for children between the ages of 8 and 12 who feel or behave anxiously, avoid situations, are afraid of doing things wrong, appear…
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Leaving a Lasting Impression. The Impact of Incunabula on Late Medieval Spirituality, Religious Practice and Visual Culture in the Low Countries
This project investigates how the first generation of Dutch printed books (the incunabula, 1473-1501) affected late medieval spirituality, religious practice and visual culture in the Low Countries.
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Photo-activation of ruthenium-decorated upconverting nanoparticles
Metal-based prodrugs based on ruthenium(II) polypyridyl complexes have proven to be very suitable for application in both photodynamic therapy (PDT) and photo-activated chemotherapy (PACT).
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Student projects
Bachelor and Master students of all chemistry related studies are more than welcome to take part in our research activities. We have projects on design and synthesis of biologically relevant compounds within an ongoing research project. Supervision, following the apprentice/teacher model, is one of…
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Barbarism Revisited: New Perspectives on an Old Concept
The figure of the barbarian has captivated the Western imagination from Greek antiquity to the present. Since the 1990s, the rhetoric of civilization versus barbarism has taken center stage in Western political rhetoric and the media. But how can the longevity and popularity of this opposition be accounted…
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Human nature and governance: soulcraft and statecraft in eleventh century China
On the 2nd of September Jiyan Qiao successfully defended a doctoral thesis and graduated.
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About us
The Bachelor Honours Programme Sustainability is a joint iniatiative by the Honours Academies of Leiden University, TU Delft and Erasmus University Rotterdam.
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Style and Society in the Prehistory of West Asia
Essays in Honour of Olivier P. Nieuwenhuyse
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Open to all, not known to all: sustaining practices with open educational resources in higher education
In higher education, Open Educational Resources (OER) are available for anyone to use, but they are not widely used.
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Monitoring the penetration process of single microneedles with varying tip diameters
Microneedles represent promising tools for delivery of drugs to the skin. However, before these microneedles can be used in clinical practice, it is essential to understand the process of skin penetration by these microneedles.
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When structure-affinity relationships meet structure-kinetics relationships: 3-((Inden-1-yl)amino)-1-isopropyl-cyclopentane-1-carboxamides as
Source: Eur J Med Chem (2015)
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Measuring science communication impact
What tools can be applied to measure the output, outcome and impact of science communication efficiently and effectively?
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Market Power and Competition Law In the Software Industry
On Thursday 11 May 2017, Qiang Yu defended his doctoral thesis ‘Market Power and Competition Law in the Software Industry’. The supervisors of the research are Professor T.R. Ottervanger and Professor S.C.G. Van den Bogaert. A brief summary of his thesis is provided below.
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Towards an effective biodiversity conservation and governance in the Pontocaspian region
Freshwater and brackish water ecosystems are arguably the most vulnerable ecosystems on earth, due to concentrated human developments in and around them. The Pontocaspian (PC) region located at the border of Europe and Asia contains a variety of brackish water ecosystems and unique inhabitants, known…
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Elite and popular religiosity among Dutch-Turkish muslims in the Netherlands
Ömer Gürlesin defended his thesis on 28 November 2018
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Focal-plane wavefront sensors for direct exoplanet imaging: Theory, simulations and on-sky demonstrations
One of the key limitations of the direct imaging of exoplanets at small angular separations are quasi-static speckles that originate from evolving non-common path aberrations (NCPA) to which the primary adaptive optics system is inherently blind. The main focus of this thesis is the development and…
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Bioorthogonal Antigens as Tool for Investigation of Antigen Processing and Presentation
In order to be able to develop effective medicine and treatments to prevent or cure autoimmune diseases or cancer we need to understand the mechanisms how they arise and what drives their course.Unravelling the fundamental molecular mechanisms influencing the onset and course of diseases such as allergies,…
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Development and application of cryo-EM tools to study the ultrastructure of microbes in changing environments
Cryogenic electron microscopy (cryo-EM) is a powerful technique used to visualize the inside of cells and to study specific protein complexes. Within this thesis, I describe the use of various cryo-EM techniques to gain insight into the structural changes of the human pathogen, Vibrio cholerae, as it…
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Student teachers’ commitment to teaching
What are relationships between student teachers’ personal characteristics, learning experiences and perception of external environmental aspects impacting teacher career and their commitment to teaching?
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The field and the classroom
The field and the classroom invites ethnographers to engage with critical and engaged pedagogies. Breaking down the barriers between fieldsite and lecture hall, this research cluster aims to interrogate the structures and values that shape anthropological and sociological education today.
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Centre for Indigenous Americas Studies
The Centre for Indigenous America Studies (CIAS) at Leiden University is designed to coordinate and promote the teaching and research of Indigenous languages, literatures, cultures and cultural heritage.
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Bankside Plants
What plants grow along ditches in the Leiden region? What does this say about vegetation quality? Could it be better? Naturalis and Leiden University's Center for Environmental Sciences are looking for your help to answer these questions.
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Photothermal circular dichroism studies of single nanoparticles
In this work, we investigate the minute circular dichroism effects of single nanoparticles.To this aim, we apply photothermal imaging with a polarization-modulated heating beam.
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Progressive Indexes
Interactive exploration of large volumes of data is increasingly common, as data scientists attempt to extract interesting information from large opaque data sets. This scenario presents a difficult challenge for traditional database systems, as (1) nothing is known about the query workload in advance,…