2,346 search results for “ f mri research” in the Public website
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The Manichaeans of Kellis: Religion, Community, and Everyday Life
Mattias Brand defended his thesis on 10 April 2019
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Crisis management
Training and Exercising in Crisis management and Emergency Control
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Residence in Tax Treaties
On Thursday 1 December 2016 at 13.45 hrs, Francisco Sepulveda Ramirez will defend his doctoral thesis ‘Residence in Tax Treaties' at the Academy Building of Leiden University. Supervisor is Professor F.A. Engelen.
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Metabolomic characterization of plant exudates and their correlation with plant defense systems
Plant exudates appeared long time ago in the history line of life in the early Devonian. They are typical saps produced by specialized cells.
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Understanding functional dynamics and conformational stability of beta-glycosidases
Due to their central physiological roles in living organisms, retaining beta-glycosidases have been the subject of tremendous research efforts to examine their structure/function relation using numerous biophysical and biochemical approaches.
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Keys to Rome
Shining a new light on the Roman world
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Singing is silver, hearing is gold: impacts of local FoxP1 knockdowns on auditory perception and gene expression in female zebra finches
The experiments described in this thesis employ local lentiviral knockdowns in brain areas of female zebra finches followed by behavioural assays consisting of preference and Go/Nogo tasks.
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Slave in a Palanquin: Colonial Servitude and Resistance in Sri Lanka
For hundreds of years, the island of Sri Lanka was a crucial stopover for people and goods in the Indian Ocean. For the Dutch East India Company, it was also a crossroads in the Indian Ocean slave trade. Slavery was present in multiple forms in Sri Lanka—then Ceylon—when the British conquered the island…
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Strategy Dynamics
In the thesis the dynamics of strategies is studied from two perspectives.In the first part of the thesis strategies are considered to be opinions present in a community.
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Beyond Friends and Foes: Immigration Policymaking in Contemporary China
On 19 September 2023 Tabitha Speelman successfully defended a doctoral thesis and graduated.
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The End of our Third Decade (volume I)
Papers written on the occasion of the 30th anniversary of the Institute of Prehistory, Volume I.
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Redox Interconversion between Metal Thiolate and Disulfide Compounds
In the last decade, the redox interconversion between metal thiolate and disulfide compounds has been extensively investigated for copper, but not for other transition metal ions.
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Library
The library of the Papyrological Institute is the most complete facility for papyrological studies in the Netherlands.
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Resolving the building blocks of galaxies in space and time
We investigate the buildup of galaxies from various vantage points. The first two chapters focus on the stellar content of galaxies, especially the distribution of stellar masses at birth and potential variations therein in various galactic environments.
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A timeless vale
Archaeological and related essays on the Jordan Valley in honour of Gerrit van der Kooij on the occasion of his sixty-fifth birthday
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The sociolinguistics of exclusion – Indexing (non)belonging in mobile communities
This is special issue of the journal Language & Communication. The papers of this issue delve into the multifaceted realm of (non)belonging.
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On hard real-time scheduling of cyclo-static dataflow and its application in system-level design
Promotor: Prof.dr. E.F.A. Deprettere, Co-promoter: Todor P. Stefanov
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American Hegemony and the Rise of Emerging Powers. Cooperation or Conflict
This book explores how changes in the patterns of cooperation and conflict among states, regional actors and transnational non-state actors have affected the rise of emerging global powers and the suggested decline of US leadership. Scholars, students and policy practitioners who are interested in the…
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Immunoproteomic Profiling of Bordetella pertussis Outer Membrane Vesicle Vaccine Reveals Broad and Balanced Humoral Immunogenicity
The current resurgence of whooping cough is alarming, and improved pertussis vaccines are thought to offer a solution. Outer membrane vesicle vaccines (omvPV) are potential vaccine candidates, but omvPV-induced humoral responses have not yet been characterized in detail.
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Oxidation catalysis on Pt and Au: complexity of simple chemistry
Promotor: J.W.M. Frenken Co-Promotores: I.M.N. Groot; L.B.F. Juurlink
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In vivo fluorescence imaging of IgG1 aggregates after subcutaneous and intravenous injection in mice
PURPOSE: To monitor the biodistribution of IgG1 aggregates upon subcutaneous (SC) and intravenous (IV) administration in mice and measure their propensity to stimulate an early immune response.
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From data to models: reducing uncertainty in benefit risk assessment: application to chronic iron overload in children
M. Danhof, Co-promotor: O.E. Della Pasqua
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Overview
Our research is aimed at a smoother and speedier transition from preclinical research to pharmacological interventions, and the delivery of drugs in the human body by use of small molecules and biologics.
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Monitoring Alzheimer's disease in transgenic mice with ultra high field magnetic resonance imaging
Promotor: H.J.M. de Groot, Co-Promotor: A. Alia
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Performance Requirement Prohibitions in International Investment Law
On Tuesday 17 October 2017 Alexandre Genest defended his PhD dissertation ‘Performance Requirement Prohibitions in International Investment Law’ as part of a double PhD programme at the Universities of Leiden and Ottawa. The Supervisors are Professors M.E. Koppenol-Laforce. F. Baetens (Universities…
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Classical and Mediterranean Archaeology
Caspar Reuvens, the world’s first Professor of Archaeology, was a prominent classical scholar and from his appointment in 1818 onwards Classical & Mediterranean Archaeology has been an important field of research in Leiden.
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Associates
Associates of Leiden University Center for Intercultural Philosophy
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Solid Bioneedle-Delivered Influenza Vaccines Are Highly Thermostable and Induce Both Humoral and Cellular Immune Responses
The potential of bioneedles to deliver influenza vaccines was investigated.
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A₃ adenosine receptor allosteric modulator induces an anti-inflammatory effect: in vivo studies and molecular mechanism of action
Source: Mediators Inflamm (2014)
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Molecular Signatures of the Evolving Immune Response in Mice following a Bordetella pertussis Infection
Worldwide resurgence of pertussis necessitates the need for improvement of pertussis vaccines and vaccination strategies.
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Early death of massive galaxies in the distant universe
Promotor: M. Franx, Co-Promotor: I.F. Labbé
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Poly-(lactic-co-glycolic-acid)-based particulate vaccines: particle uptake by dendritic cells is a key parameter for immune activation
Poly(lactic-co-glycolic acid) (PLGA) particles have been extensively studied as biodegradable delivery system to improve the potency and safety of protein-based vaccines. In this study we analyzed how the size of PLGA particles, and hence their ability to be engulfed by dendritic cells (DC), affects…
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Establishing State Responsibility in the Absence of Effective Government
On 16 June 2020, Andrea Varga defended her thesis 'Establishing State Responsibility in the Absence of Effective Government'. The doctoral research was supervised by Prof. N.J. Schrijver and Prof. F. Baetens (University of Oslo).
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Mediating Islam in Post-Suharto Indonesia: Performing Dakwah through Popular TV Shows
On the 9th of November Syahril Siddik successfully defended a doctoral thesis and graduated.
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Arabic in context: celebrating 400 years of Arabic at Leiden university
The edited volume 'Arabic in context: celebrating 400 years of Arabic at Leiden University' edited by Ahmad Al-Jallad is out. The volume contains the contributions to the 2013 conference with the same title, held at Leiden University and was published as part of Brill's the Studies in Semitics Language…
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Interactions of nutrients and pesticides and their effects on aquatic macrofauna
Can we distinguish the effects of pesticides from other abiotic and biotic factors that occur in the field? And how do these factors interact with pesticides?
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Mediating from Within. Metaxical Amplification as an Alternative Sonic Environment for Classical Music Performance
Heloisa’s doctoral research examines classical music performance from a curatorial perspective, reflecting upon and challenging the traditional configuration of performance environments.
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Leaving a Lasting Impression. The Impact of Incunabula on Late Medieval Spirituality, Religious Practice and Visual Culture in the Low Countries
This project investigates how the first generation of Dutch printed books (the incunabula, 1473-1501) affected late medieval spirituality, religious practice and visual culture in the Low Countries.
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Software and data for circular economy assessment
This thesis investigates how the assessment of circular economy (CE) at the macro-economic level can be facilitated and promoted.
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De verzamelwoede van Martinus van Marum (1750-1837) en de ouderdom van de aarde
Promotor: F.J. van Lunteren, E. Jorin
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Monitoring the penetration process of single microneedles with varying tip diameters
Microneedles represent promising tools for delivery of drugs to the skin. However, before these microneedles can be used in clinical practice, it is essential to understand the process of skin penetration by these microneedles.
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When structure-affinity relationships meet structure-kinetics relationships: 3-((Inden-1-yl)amino)-1-isopropyl-cyclopentane-1-carboxamides as
Source: Eur J Med Chem (2015)
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Taxation of Cross-border Inheritances and Donations
On 3 June 2021, Vassilis Dafnomilis defended his thesis 'Taxation of Cross-border Inheritances and Donations'. The doctoral research was supervised by Prof. F. Sonneveldt and Prof. S. Douma (UvA).
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Modulation of the immune system for treatment of atherosclerosis
Cardiovascular diseases are the primary cause of death in the world with atherosclerosis as primary underlying cause.
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Mining the kinematics of discs to hunt for planets in formation
Detecting planets during their formation stages is crucial for understanding the history and diversity of fully developed planetary systems like our own. However, observing young planets directly is challenging because they are often deeply embedded within their host protoplanetary discs, rich in gas…
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Data mining and algorithm development
Due to the modern techniques of combinatorial chemistry and high-throughput screening, data on the biological activity of many millions of compounds is known. However, it is still very difficult to transfer this data into knowledge: if we know that compounds A and B bind to a certain protein with high…
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Extra-curricular
Get the most out of your studies at Leiden University by taking part in our extracurricular activities.
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Contact
If there is anything you want to know about the Philosophy: Global and Comparative Perspectives bachelor’s programme, or if, perhaps, there’s another way in which you think we might be able to help you, don’t hesitate to get in touch with us.
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Affinity
Designing and synthesizing high-affinity ligands for a given drug target have always been among the more important challenges in the drug discovery process.