3,333 search results for “ f mri research” in the Public website
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Resolving the building blocks of galaxies in space and time
We investigate the buildup of galaxies from various vantage points. The first two chapters focus on the stellar content of galaxies, especially the distribution of stellar masses at birth and potential variations therein in various galactic environments.
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A timeless vale
Archaeological and related essays on the Jordan Valley in honour of Gerrit van der Kooij on the occasion of his sixty-fifth birthday
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The sociolinguistics of exclusion – Indexing (non)belonging in mobile communities
This is special issue of the journal Language & Communication. The papers of this issue delve into the multifaceted realm of (non)belonging.
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On hard real-time scheduling of cyclo-static dataflow and its application in system-level design
Promotor: Prof.dr. E.F.A. Deprettere, Co-promoter: Todor P. Stefanov
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American Hegemony and the Rise of Emerging Powers. Cooperation or Conflict
This book explores how changes in the patterns of cooperation and conflict among states, regional actors and transnational non-state actors have affected the rise of emerging global powers and the suggested decline of US leadership. Scholars, students and policy practitioners who are interested in the…
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Immunoproteomic Profiling of Bordetella pertussis Outer Membrane Vesicle Vaccine Reveals Broad and Balanced Humoral Immunogenicity
The current resurgence of whooping cough is alarming, and improved pertussis vaccines are thought to offer a solution. Outer membrane vesicle vaccines (omvPV) are potential vaccine candidates, but omvPV-induced humoral responses have not yet been characterized in detail.
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Oxidation catalysis on Pt and Au: complexity of simple chemistry
Promotor: J.W.M. Frenken Co-Promotores: I.M.N. Groot; L.B.F. Juurlink
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In vivo fluorescence imaging of IgG1 aggregates after subcutaneous and intravenous injection in mice
PURPOSE: To monitor the biodistribution of IgG1 aggregates upon subcutaneous (SC) and intravenous (IV) administration in mice and measure their propensity to stimulate an early immune response.
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From data to models: reducing uncertainty in benefit risk assessment: application to chronic iron overload in children
M. Danhof, Co-promotor: O.E. Della Pasqua
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Overview
Our research is aimed at a smoother and speedier transition from preclinical research to pharmacological interventions, and the delivery of drugs in the human body by use of small molecules and biologics.
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Monitoring Alzheimer's disease in transgenic mice with ultra high field magnetic resonance imaging
Promotor: H.J.M. de Groot, Co-Promotor: A. Alia
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Performance Requirement Prohibitions in International Investment Law
On Tuesday 17 October 2017 Alexandre Genest defended his PhD dissertation ‘Performance Requirement Prohibitions in International Investment Law’ as part of a double PhD programme at the Universities of Leiden and Ottawa. The Supervisors are Professors M.E. Koppenol-Laforce. F. Baetens (Universities…
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Classical and Mediterranean Archaeology
Caspar Reuvens, the world’s first Professor of Archaeology, was a prominent classical scholar and from his appointment in 1818 onwards Classical & Mediterranean Archaeology has been an important field of research in Leiden.
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Associates
Associates of Leiden University Center for Intercultural Philosophy
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Solid Bioneedle-Delivered Influenza Vaccines Are Highly Thermostable and Induce Both Humoral and Cellular Immune Responses
The potential of bioneedles to deliver influenza vaccines was investigated.
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A₃ adenosine receptor allosteric modulator induces an anti-inflammatory effect: in vivo studies and molecular mechanism of action
Source: Mediators Inflamm (2014)
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Molecular Signatures of the Evolving Immune Response in Mice following a Bordetella pertussis Infection
Worldwide resurgence of pertussis necessitates the need for improvement of pertussis vaccines and vaccination strategies.
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Early death of massive galaxies in the distant universe
Promotor: M. Franx, Co-Promotor: I.F. Labbé
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Poly-(lactic-co-glycolic-acid)-based particulate vaccines: particle uptake by dendritic cells is a key parameter for immune activation
Poly(lactic-co-glycolic acid) (PLGA) particles have been extensively studied as biodegradable delivery system to improve the potency and safety of protein-based vaccines. In this study we analyzed how the size of PLGA particles, and hence their ability to be engulfed by dendritic cells (DC), affects…
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Establishing State Responsibility in the Absence of Effective Government
On 16 June 2020, Andrea Varga defended her thesis 'Establishing State Responsibility in the Absence of Effective Government'. The doctoral research was supervised by Prof. N.J. Schrijver and Prof. F. Baetens (University of Oslo).
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Mediating Islam in Post-Suharto Indonesia: Performing Dakwah through Popular TV Shows
On the 9th of November Syahril Siddik successfully defended a doctoral thesis and graduated.
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Arabic in context: celebrating 400 years of Arabic at Leiden university
The edited volume 'Arabic in context: celebrating 400 years of Arabic at Leiden University' edited by Ahmad Al-Jallad is out. The volume contains the contributions to the 2013 conference with the same title, held at Leiden University and was published as part of Brill's the Studies in Semitics Language…
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Interactions of nutrients and pesticides and their effects on aquatic macrofauna
Can we distinguish the effects of pesticides from other abiotic and biotic factors that occur in the field? And how do these factors interact with pesticides?
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Mediating from Within. Metaxical Amplification as an Alternative Sonic Environment for Classical Music Performance
Heloisa’s doctoral research examines classical music performance from a curatorial perspective, reflecting upon and challenging the traditional configuration of performance environments.
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Leaving a Lasting Impression. The Impact of Incunabula on Late Medieval Spirituality, Religious Practice and Visual Culture in the Low Countries
This project investigates how the first generation of Dutch printed books (the incunabula, 1473-1501) affected late medieval spirituality, religious practice and visual culture in the Low Countries.
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Software and data for circular economy assessment
This thesis investigates how the assessment of circular economy (CE) at the macro-economic level can be facilitated and promoted.
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De verzamelwoede van Martinus van Marum (1750-1837) en de ouderdom van de aarde
Promotor: F.J. van Lunteren, E. Jorin
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Monitoring the penetration process of single microneedles with varying tip diameters
Microneedles represent promising tools for delivery of drugs to the skin. However, before these microneedles can be used in clinical practice, it is essential to understand the process of skin penetration by these microneedles.
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When structure-affinity relationships meet structure-kinetics relationships: 3-((Inden-1-yl)amino)-1-isopropyl-cyclopentane-1-carboxamides as
Source: Eur J Med Chem (2015)
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Taxation of Cross-border Inheritances and Donations
On 3 June 2021, Vassilis Dafnomilis defended his thesis 'Taxation of Cross-border Inheritances and Donations'. The doctoral research was supervised by Prof. F. Sonneveldt and Prof. S. Douma (UvA).
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Modulation of the immune system for treatment of atherosclerosis
Cardiovascular diseases are the primary cause of death in the world with atherosclerosis as primary underlying cause.
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Mining the kinematics of discs to hunt for planets in formation
Detecting planets during their formation stages is crucial for understanding the history and diversity of fully developed planetary systems like our own. However, observing young planets directly is challenging because they are often deeply embedded within their host protoplanetary discs, rich in gas…
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Data mining and algorithm development
Due to the modern techniques of combinatorial chemistry and high-throughput screening, data on the biological activity of many millions of compounds is known. However, it is still very difficult to transfer this data into knowledge: if we know that compounds A and B bind to a certain protein with high…
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Extra-curricular
Get the most out of your studies at Leiden University by taking part in our extracurricular activities.
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Contact
If there is anything you want to know about the Philosophy: Global and Comparative Perspectives bachelor’s programme, or if, perhaps, there’s another way in which you think we might be able to help you, don’t hesitate to get in touch with us.
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Affinity
Designing and synthesizing high-affinity ligands for a given drug target have always been among the more important challenges in the drug discovery process.
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3rd History and Philosophy of Physics in the Netherlands Workshop
Conference
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Previous OSCL events and OSCL member initiatives
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Supramolecular and Biomaterials Chemistry
Alexander Kros studies supramolecular systems in a biological environment. The unifying theme between the projects in my lab is specific molecular recognition, i.e. the intermolecular interaction between complementary molecules with high affinity and selectivity. Studying, imitating and dissecting processes…
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Memory and Identity
Research conducted in this group aims at furthering our understanding of how communities and individuals deal with social change, conflict and trauma through remembrance and commemoration as well as forgetting in the arts.
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The domestic implements of the Single Grave Culture: the case of the Noord-Holland province
The use-wear analysis of domestic implements provided new insights of the Single Grave Culture population in the Netherlands.
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Chromatin organisation & dynamics
The genomic DNA of every organism is organized and compacted in order to fit inside the cell. This is achieved by the joint action of numerous architectural proteins that aid in folding the genome. Genome folding is tightly interconnected with transcription, with genes in certain regions being silenced,…
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New research reveals link between finger tapping and Alzheimer's
Suddenly getting lost, failing to recognise family members, or forgetting words and names are well-known symptoms of Alzheimer's disease. Psychologists have now discovered that the disease also manifests in more subtle ways: through the rhythm of finger tapping.
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The role of research in university teaching: A comparison of Chinese and Dutch teachers
The main interest of this research concerns the beliefs and perceptions of Chinese and Dutch university teachers regarding the role of research in university teaching, and how these beliefs and perceptions can be explained by their cultural, institutional and individual background characteristics.
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MoRRI – Monitoring the evolution and benefits of responsible research and innovation
Responsible Research and Innovation (RRI) implies that societal actors (researchers, citizens, policy makers, business, third sector organisations, etc.) work together during the whole research and innovation process in order to better align both the process and its outcomes with the values, needs and…