2,362 search results for “modelling 26 simulations” in the Public website
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QS rankings: Law at Leiden ranked 26 worldwide
The results of the QS World University Rankings by Subject 2019 were announced last week. Law at Leiden has achieved 26th place of this worldwide ranking. It is the highest ranking for law programmes in the Netherlands.
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using population pharmacokinetic and physiology based pharmacokinetic modeling approaches
In this thesis population pharmacokinetic and physiologically-based pharmacokinetic (PBPK) approaches were applied to investigate the influence of glomerular filtration (GF) and active tubular secretion (ATS) on renal clearance in children.
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These researchers turn mathematical models into healthcare solutions
Two Leiden researchers have demonstrated how mathematics can improve our healthcare. Daniel Gomon has developed a model that contributes to the quality of care in hospitals. Marta Spreafico works on an app that helps physicians make well-informed decisions about the treatment of a certain type of cancer.…
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Personalised medicine for multiple outcomes: methods and application
The main objective of this thesis was to develop clinically relevant survival models for patients with high-grade soft tissue sarcoma of the extremities, in particular the development and validation of prediction models for use in clinical practice.
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Anisotropy in cell mechanics
Mechanical interactions between cells and their environment play an important role in many biological processes.
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dr. ir. Hai-Xiang Lin working on Data Analytics for Environmental Modelling joins CML
Prof.dr.ir. Hai-Xiang Lin is appointed on 1 March 2015 as part-time professor on Data Analytics for Environmental Modelling at CML on behalf of the R. Timman foundation. He will join the CML-department of Industrial Ecology. He has a position at the Department of Applied Mathematics at the Faculty…
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Sebastiaan Deetman
Science
s.p.deetman@cml.leidenuniv.nl | +31 71 527 5616
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Mirko Forastiere
Science
m.forastiere@cml.leidenuniv.nl | +31 71 527 2727
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Ruben Huele
Science
huele@cml.leidenuniv.nl | +31 71 527 FLEX
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Learning from small samples
Learning from small data sets in machine learning is a crucial challenge, especially when dealing with data imbalances and anomaly detection. This thesis delves into the challenges and methodologies of learning from small datasets in machine learning, with a particular focus on addressing data imbalances…
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Visualizing cityscapes of Classical antiquity
This study aims to make a practical contribution to a new understanding and use of 3D reconstructions, namely as ‘laboratories’ to test hypotheses and visualize, evaluate and discuss alternative interpretations.
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More efficient drug development with the help of computer models
The coronavirus has the world in its grip. Finding a cure has never been more important. Unfortunately, the development of new drugs for treatment of the COVID-19 disease caused by the virus and development of a vaccine are complex, lengthy, and above all costly processes. With the help of computer…
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Institute of Biology Leiden
The Institute of Biology Leiden (IBL) is an internationally oriented institute for research and education in biology. We are part of the Faculty of Science at Leiden University.
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Winner of the Model Gamification Contest
Dave R. Stikkolorum, Michel R.V. Chaudron, Oswald de Bruin won the Best Paper Award of the Model Gamification Contest at the ACM/IEEE Models 2012 Conference for their paper: The Art Of Software Design, a Video Game for Learning Design Principles.
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New flowchart to eliminate Universe models
Cosmologists have many possible models for the Universe, of which only one can be true. A new flowchart will eliminate some of them when two specific Universe features are accurately measured. Publication in Physical Review D on 7 November.
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Rob van Wijk
Science
r.c.van.wijk@lacdr.leidenuniv.nl | +31 71 527 4505
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Strings and AdS/CFT at finite density
Promotor: Prof.dr. J. Zaanen, A. Parnachev
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The Role of Linker DNA in Chromatin Fibers
The genetic information of all living organisms is contained in their DNA. Cells modify the degree of DNA compaction by epigenetics, which largely determines what genes are read out and which genes are transcriptionally silent.
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Bioactivity based quality control for Chinese herbal medicine
Can we establish a new quality control system for herbal medicines that is based on bioactivity rather than a few abundant chemicals?
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Complexity Models to Prevent Financial Crashes
The financial system needs complexity theory to predict economic crises like the 2008 meltdown. An international team of scientists, including Leiden physicist Diego Garlaschelli, state this in a paper published in Science on February 19th.
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Franco Donati
Science
f.donati@cml.leidenuniv.nl | +31 71 527 4571
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Dynamics of a β-lactamase
BlaC is the β-lactamase of Mycobacterium tuberculosis. We show that it can recover from inhibition by clavulanic acid and that phosphate helps it do so.
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New technique to study vascular growth
Sonja Boas developed new techniques to study vascular growth computationally. The results of her research provide a better understanding into mechanisms behind vascular growth, which is relevant to the development of medical therapies. She defends her thesis 'Computational modeling of angiogenesis'…
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Nicolas Navarre
Science
n.h.navarre@cml.leidenuniv.nl | +31 71 527 2727
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Kyra Verboon
Faculteit der Sociale Wetenschappen
k.e.verboon@fsw.leidenuniv.nl | +31 71 527 2727
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Dirk-Jan Kok
Science
d.d.kok@cml.leidenuniv.nl | +31 71 527 2727
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Myrthe Veenman
Faculteit der Sociale Wetenschappen
m.veenman@fsw.leidenuniv.nl | +31 71 527 2727
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Mathilde Verdam
Faculteit der Sociale Wetenschappen
m.g.e.verdam@fsw.leidenuniv.nl | +31 71 527 3789
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Weilin Huang
Science
w.huang@cml.leidenuniv.nl | +31 71 527 2727
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Carina Harpprecht
Science
c.i.harpprecht@cml.leidenuniv.nl | +31 71 527 2727
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Carlotta Rieble
Faculteit der Sociale Wetenschappen
c.l.rieble@fsw.leidenuniv.nl | +31 71 527 2727
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Anne Uilhoorn
Science
a.g.uilhoorn@cml.leidenuniv.nl |
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Amie Corbin
Science
a.e.corbin@cml.leidenuniv.nl | +31 71 527 2727
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Jinhui Zhou
Science
j.zhou.12@cml.leidenuniv.nl | +31 71 527 2727
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Henk Kelderman
Faculteit der Sociale Wetenschappen
h.kelderman@fsw.leidenuniv.nl | +31 71 527 2727
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World news: eleven asteroids on a collision course with Earth
The discovery that eleven asteroids might collide with our Earth has become world news. The research of three Leiden astronomers has appeared on more than 190 news sites worldwide, from America to China. They developed and trained an artificial neural network for this discovery.
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Conference: Jan van Eyck and the Northern Renaissance in Bruges (Brugge, 25/26 April)
Henri Pirenne Institute for Medieval Studies (Ghent University) & BRON Research Centre (Musea Brugge) are organising a two-day conference on new and ongoing research on Jan van Eyck and the Northern Renaissance in Bruges.
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Five principles to preserve social trust in scientific modelling
Experts from several disciplines have raised concerns about the use of seemingly precise models to guide policies in matters as complex as the current Covid-19 pandemic. 22 scholars wrote down five principles on how to responsibly use scientific models. This comment was published in Nature on 24 June…
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Lecture: Politics and Religion in the Middle Ages and Today (RUG, June 26)
In the context of the summer school "Medieval Religon" prof. Christopher M. Bellitto (Kean University) will give a keynote lecture on June 26th: "Politics and Religion in the Middle Ages and Today: Thoughts of an American Medievalist". This lecture is also open to those interested who do not participate…
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Leiden econophysics model tested best by central banks
A full overview of all loans and debts between banks would help preventing a new financial collapse. But banks do not provide this information. An econophysics model by Diego Garlaschelli and collaborators reconstructs the most probable situation and finishes first place in two independent tests.
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A piece of the Universe in the computer
Simulations of galaxies help researchers understand astronomical observations better. The EAGLE simulation, a large project in which Leiden astronomers play a leading role, shows the evolution of the Universe, from just after the Big Bang to the present day.
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Tracing the journey of the sun and the solar siblings through the Milky Way
Supervisor: S.F. Portegies Zwart Co-Supervisor: A.G.A. Brown
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On the amount of sieving in factorization methods
Promotoren: R. Tijdeman, A.K. Lenstra, Co-promotor: H.J.J. te Riele
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Stepwise latent class analysis
The main methodological aspects of the use of stepwise LCA estimators under different circumstances.
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The evolution and plasticity of life histories upon variation in nutrition: on aging focused integrative approach
Promotores: Prof.dr. P.M. Brakefield, Prof.dr. B.J. Zwaan (Wageningen Universiteit)
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Computer models chart extensive Caribbean inter-island networks
The precolonial inhabitants of the Caribbean islands communicated, travelled, and exchanged objects and ideas along an expansive inter-island network. New methods of computer modeling shed light on these networks. Emma Slayton is set to discuss her work on this topic at her Defense on the 12th of Se…
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Cholesterol metabolism and hematopoiesis interaction in atherothrombosis
Cardiovascular disease is the leading cause of death worldwide.
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Identifying the origins of galaxy formation
This thesis investigates how galaxies form and what diversifies the evolutionary histories of galaxies.
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New vegetation models can improve climate change predictions
A new study in Nature Plants has explored the most important organising principles that control vegetation behaviour. The insights from this study can be used to improve predictions on climate change. Leiden scientists Peter van Bodegom and Nadia Soudzilovskaia participated in the study.
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New Business models for the Legal Services Market
Linking Empirical Academic thinking with Legal Practice. Internationally and particularly in the Netherlands. By René Orij, April, 2016.