827 search results for “modelling simulations” in the Public website
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Tom O'Brien
Science
obrien@lorentz.leidenuniv.nl | +31 71 527 5568
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Tessa Verhoef
Science
t.verhoef@liacs.leidenuniv.nl | +31 71 527 7903
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Ramira van der Meulen
Science
a.van.der.meulen@liacs.leidenuniv.nl | +31 71 527 2727
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Galaxy formation traced by heavy element pollution
Galaxies form and evolve through close interaction with their surroundings. As a result, the heavy elements ('metals') that are synthesized in stars, are found both inside and outside galaxies.
- Mathematical Institute
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Antiviral Pharmacology
The focus of the Antiviral Pharmacology group led by Anne-Grete Märtson is optimizing antiviral therapy for different viral infections by conducting clinical trials and using innovative computational and dynamic laboratory methodologies.
- About this minor
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using population pharmacokinetic and physiology based pharmacokinetic modeling approaches
In this thesis population pharmacokinetic and physiologically-based pharmacokinetic (PBPK) approaches were applied to investigate the influence of glomerular filtration (GF) and active tubular secretion (ATS) on renal clearance in children.
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These researchers turn mathematical models into healthcare solutions
Two Leiden researchers have demonstrated how mathematics can improve our healthcare. Daniel Gomon has developed a model that contributes to the quality of care in hospitals. Marta Spreafico works on an app that helps physicians make well-informed decisions about the treatment of a certain type of cancer.…
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Personalised medicine for multiple outcomes: methods and application
The main objective of this thesis was to develop clinically relevant survival models for patients with high-grade soft tissue sarcoma of the extremities, in particular the development and validation of prediction models for use in clinical practice.
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Anisotropy in cell mechanics
Mechanical interactions between cells and their environment play an important role in many biological processes.
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Helmut Schiessel Group - Theoretical Physics of Life Processes
The group Theoretical Physics of Life Processes, led by Helmut Schiessel, focuses on the physics of chromatin, the DNA-protein complex that fills the nuclei of eukaryotic cells.
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Expertise
The CIGR brings together a diverse range of unique expertise in genome research rooted in biology, chemistry and physics. Members of the CIGR investigate genome folding and genome transactions. An important aspect is direct as well as long term relevance for medicine. The available expertise extends…
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Sebastiaan Deetman
Science
s.p.deetman@cml.leidenuniv.nl | +31 71 527 5616
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Mirko Forastiere
Science
m.forastiere@cml.leidenuniv.nl | +31 71 527 2727
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Ruben Huele
Science
huele@cml.leidenuniv.nl | +31 71 527 FLEX
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Laboratory for Astrophysics
We simulate interstellar clouds with special plasma expansions and chemical reactions on icy dust grains to be measured in ultra-high vacuum setups. This provides the data necessary to guide and interpret astronomical observations and to model reaction networks in space. [Harold Linnartz]
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Learning from small samples
Learning from small data sets in machine learning is a crucial challenge, especially when dealing with data imbalances and anomaly detection. This thesis delves into the challenges and methodologies of learning from small datasets in machine learning, with a particular focus on addressing data imbalances…
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Visualizing cityscapes of Classical antiquity
This study aims to make a practical contribution to a new understanding and use of 3D reconstructions, namely as ‘laboratories’ to test hypotheses and visualize, evaluate and discuss alternative interpretations.
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Winner of the Model Gamification Contest
Dave R. Stikkolorum, Michel R.V. Chaudron, Oswald de Bruin won the Best Paper Award of the Model Gamification Contest at the ACM/IEEE Models 2012 Conference for their paper: The Art Of Software Design, a Video Game for Learning Design Principles.
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New flowchart to eliminate Universe models
Cosmologists have many possible models for the Universe, of which only one can be true. A new flowchart will eliminate some of them when two specific Universe features are accurately measured. Publication in Physical Review D on 7 November.
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Strings and AdS/CFT at finite density
Promotor: Prof.dr. J. Zaanen, A. Parnachev
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Bioactivity based quality control for Chinese herbal medicine
Can we establish a new quality control system for herbal medicines that is based on bioactivity rather than a few abundant chemicals?
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The Role of Linker DNA in Chromatin Fibers
The genetic information of all living organisms is contained in their DNA. Cells modify the degree of DNA compaction by epigenetics, which largely determines what genes are read out and which genes are transcriptionally silent.
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Master Projects
The following master research projects are currently available.
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Complexity Models to Prevent Financial Crashes
The financial system needs complexity theory to predict economic crises like the 2008 meltdown. An international team of scientists, including Leiden physicist Diego Garlaschelli, state this in a paper published in Science on February 19th.
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Franco Donati
Science
f.donati@cml.leidenuniv.nl | +31 71 527 4571
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Explaining European Union Decision-Making: Insights from the Natural and Social Sciences (EUDINS)
How do processes of coalition-formation influence patterns of decision-making in the European Union?
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Dynamics of a β-lactamase
BlaC is the β-lactamase of Mycobacterium tuberculosis. We show that it can recover from inhibition by clavulanic acid and that phosphate helps it do so.
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Socially Embedded AI Systems
This interdisciplinary research project explores several adaptive machine learning methods which can give insight into the interaction between human and machine. The ultimate goal is open and natural communication between humans and AI that should result in mutual trust, cooperation and coordination…
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Nicolas Navarre
Science
n.h.navarre@cml.leidenuniv.nl | +31 71 527 2727
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Kyra Verboon
Faculteit der Sociale Wetenschappen
k.e.verboon@fsw.leidenuniv.nl | +31 71 527 2727
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Dirk-Jan Kok
Science
d.d.kok@cml.leidenuniv.nl | +31 71 527 2727
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Myrthe Veenman
Faculteit der Sociale Wetenschappen
m.veenman@fsw.leidenuniv.nl | +31 71 527 2727
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Mathilde Verdam
Faculteit der Sociale Wetenschappen
m.g.e.verdam@fsw.leidenuniv.nl | +31 71 527 3789
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Weilin Huang
Science
w.huang@cml.leidenuniv.nl | +31 71 527 2727
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Carina Harpprecht
Science
c.i.harpprecht@cml.leidenuniv.nl | +31 71 527 2727
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Carlotta Rieble
Faculteit der Sociale Wetenschappen
c.l.rieble@fsw.leidenuniv.nl | +31 71 527 2727
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Anne Uilhoorn
Science
a.g.uilhoorn@cml.leidenuniv.nl |
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Amie Corbin
Science
a.e.corbin@cml.leidenuniv.nl | +31 71 527 2727
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Jinhui Zhou
Science
j.zhou.12@cml.leidenuniv.nl | +31 71 527 2727
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Henk Kelderman
Faculteit der Sociale Wetenschappen
h.kelderman@fsw.leidenuniv.nl | +31 71 527 2727
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Fermions and Bosons: Excitons in strongly correlated materials
Promotors: Prof.dr. J. Zaanen, Prof.dr.ir. H. Hilgenkamp
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Leiden econophysics model tested best by central banks
A full overview of all loans and debts between banks would help preventing a new financial collapse. But banks do not provide this information. An econophysics model by Diego Garlaschelli and collaborators reconstructs the most probable situation and finishes first place in two independent tests.
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Tracing the journey of the sun and the solar siblings through the Milky Way
Supervisor: S.F. Portegies Zwart Co-Supervisor: A.G.A. Brown
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On the amount of sieving in factorization methods
Promotoren: R. Tijdeman, A.K. Lenstra, Co-promotor: H.J.J. te Riele
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Stepwise latent class analysis
The main methodological aspects of the use of stepwise LCA estimators under different circumstances.
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The evolution and plasticity of life histories upon variation in nutrition: on aging focused integrative approach
Promotores: Prof.dr. P.M. Brakefield, Prof.dr. B.J. Zwaan (Wageningen Universiteit)
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Astronomy Research (MSc)
The master's specialisation Astronomy Research at Leiden University students focus on astronomical data analysis using models and large-scale simulation, combining the fields of Astronomy, Physics, Mathematics and Computer Science.
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Cholesterol metabolism and hematopoiesis interaction in atherothrombosis
Cardiovascular disease is the leading cause of death worldwide.