1,347 search results for “global gene regulation” in the Public website
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Vriesendorp and prof. Wessels included in the 2020 Lawdragon Leading Global Restructuring & Insolvency Lists
Prof. Vriesendorp and prof. Wessels have been recognized in the 2020 Lawdragon list of 500 Leading Global Restructuring & Insolvency Lawyers. Prof. Haentjens has been recognized in the 2020 Lawdragon Leading Global Restructuring Advisors & Consultants guide.
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Transatlantic Trade and Investment Partnership (TTIP): an EU perspective on global economic governance
On 4-5 December the Europa Institute and the Faculty of Governance and Global Affairs of Leiden University organize a conference on the Transatlantic Trade and Investment Partnership (TTIP).
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At the Hinge of the Nomadic and Sedentary Worlds: A Multi-disciplinary approach
Episode 1: The Golden Horde in a Global Perspective: Imperial Strategies. This project intends to challenge the conventional way of considering the nomadic state organizations and the role of Nomads in world history.
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Nicole de Voogd appointed as Professor Global change and marine ecosystems
As of 1 May 2018, Nicole de Voogd has been appointed as Professor by special appointment Global change and marine ecosystems at the Institute of Environmental Sciences (CML). She is currently senior researcher at Naturalis Biodiversity Center in the field of tropical marine ecosystems.
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Evolution & Biodiversity in Animal Sciences
Animal Sciences’ contributions to the Evolution & Biodiversity research theme include evo-devo research, the evolution of cognitive and behavioural traits, and the evolutionary mechanisms of stress adaptation. This research involves both indoor and outdoor studies.
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Evaluation of synergistic effects of Chinese herbal medicine and natural compounds on cancers
What are the biological effects of Chinese herbal medicine in regulation of cancer cell metastasis?
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Linking soil microbial community dynamics to N2O emission after bioenergy residue amendments
Vinasse is a major by-product generated by the sugarcane biofuel industry. It is a source of microbes, nutrients and organic matter and often it is recycled as fertilizer.
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Kinetics for drug discovery – The first step towards an improved drug discovery paradigm
Supervisor: Indira Nederpelt
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François Mesnard
PhD at Université de Picardie Jules Verne, Amiens - France
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Reactive Copolypept(o)ides as Novel Material for Systemic siRNA Delivery
The aim of the project is the development of polypept(o)ide-based delivery systems to use siRNA as systemic applicated therapeutic agent against e.g. solid tumors
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Agrobacterium-mediated protein therapy for genome editing
Is translocation of nucleases possible via Agrobacterium T4SS and is it efficient enough for mutagenesis?
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Evolution and development of flowers, fruits and inflorescences of Phalaenopsis and other orchid species
The study of orchid flowers, fruits, and inflorescences is crucial due to the remarkable diversity of orchid species and their unique adaptations to pollinators and seed dispersers. However, our understanding of the evolution and development of these organs within the orchid family remains limited.
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Mycobacterial dihydrofolate reductase inhibitors identified using chemogenomic methods and in vitro validation
Source: PLoS ONE, Volume 10, Issue 3 (2015)
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Nucleosome stacking in chromatin fibers probed with single-molecule force- and torque-spectroscopy
In human cells, a meter-long DNA is condensed inside a micrometer-sized cell nucleus. Simultaneously, the genetic code must remain accessible for its replication and transcription to functional proteins.
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The EUROLITHIC project
Nowadays, most Europeans speak a language belonging to the Indo-European language family. However, very different languages were spoken on our continent before the arrival of the Indo-Europeans. The EUROLITHIC project tries to find answers to the question which languages these were and where they came…
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Molecular Signatures of the Evolving Immune Response in Mice following a Bordetella pertussis Infection
Worldwide resurgence of pertussis necessitates the need for improvement of pertussis vaccines and vaccination strategies.
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Intercellular Skin Barrier Lipid Composition and Organization in Netherton Syndrome Patients
Netherton Syndrome (NTS) is a rare genetic skin disease caused by mutations in the serine protease inhibitor Kazal-type 5 gene, which encodes the lympho-epithelial Kazal-type-related inhibitor. NTS patients have a profound impaired skin barrier function. Because SC lipids play a crucial role in the…
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Zebrafish as vertebrate model of Gaucher disease
Lysosomal storage disorders (LSDs) are a group of orphan diseases characterized by lysosomal dysfunction or impaired lysosomal catabolism and affect collectively about 1 in 5000 live births.
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Another Brick in the Wall: The role of the actinobacterial cell wall in antibiotic resistance, phylogeny and development
Streptomyces are multicellular, Gram-positive bacteria in the phylum of actinobacteria which produce a high amount of bioactive natural products of which the expression is tightly coordinated with the life cycle.
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Genetic and environmental factors determining heterogeneity in preservation stress resistance of Aspergillus niger conidia
Fungal food spoilage often starts with a contamination with spores. Experimental data strongly indicate the existence of subpopulations of spores with different levels of resistance to preservation methods.
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Social Anxiety and School Refusal
When and how does social anxiety develop? How can it go astray in some adolescents? How can we help troubled young people to attend school regularly and return to a normal developmental pathway?
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Finding and valorizing new antibiotics using AI
Antibiotics are a class of medicine most people take for granted. But pathogenic bacteria are becoming more and more resistant to our antibiotics, and this poses a great challenge for future treatments. There is thus a great societal need to identify new molecules that can address new targets and be…
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Lipid to protein ratio plays an important role in the skin barrier function of atopic eczema patients
The barrier function of the skin is primarily provided by the stratum corneum (SC), the outermost layer of the skin. Skin barrier impairment is thought to be a primary factor in the pathogenesis of atopic eczema (AE).
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Lipid to protein ratio plays an important role in the skin barrier function of atopic eczema patients
OBJECTIVES: To determine whether the lipid/protein ratio and the total dry SC mass per surface area are related with the skin barrier function of controls and AE patients.
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Shy parent, shy child?
Delineating psychophysiological endophenotypes of social anxiety disorder
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Phenoconversion
Pharmacogenetics is nowadays increasingly incorporated in the clinic to better predict pharmacokinetics and optimize dosing regimens of drug treatments. While this approach has been successful and improved our prediction of drug metabolism, drug levels within patients may still commonly deviate between…
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BioTherapeutics (MSc)
The master’s specialisation BioTherapeutics at Leiden University is a two-year programme which trains students in research in specific drug delivery techniques. The programme also examines the development of new therapeutic approaches to treat immune-based disorders, such as atherosclerosis, metabolic…
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Resolving rapid radiations
What are the phylogenetic relationships among the members of speciation bursts?
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Evolutionary traps – Balanced lethal systems
How do balanced lethal systems originate and persist in nature?
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Koops awarded with Jean Monnet Chair on ‘The EU’s Role in Security and Global Affairs’
Joachim Koops, Professor of Security Studies and Scientific Director of Leiden University’s Institute of Security and Global Affairs (ISGA) has been awarded a ‘Jean Monnet Chair’ with a focus on ‘The European Union’s Role in Security and Global Affairs’ (EURISGA).
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suffering: New perspectives on the Ethics of Suffering for Critical Global Health and Justice
Can suffering be positive? Currently dominant discourses, primarily voiced through human rights activism and humanitarianism, maintain the opposite: suffering, mentally and physically, has to be avoided and where it exists, it has to be reduced.
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Postdoc Computational Modeling for Drug Safety Prediction
Science, Leiden Academic Centre for Drug Research (LACDR)
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Catherine Harwood: ‘The Hague, a global epicentre for international law and justice’
Catherine Harwood joined the Grotius Centre in The Hague a few years ago. She received her Advanced Master’s degree in Public International Law in 2012 and continued her PhD studies at Leiden University.
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Global Exploration Grant awarded to Dr. Alexander Geurds for field research in Nicaragua
The proposed investigation focuses on the Pre-Hispanic archaeological site Aguas Buenas recently documented by Dr. Alexander Geurds
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Scientists of the Faculty of Governance and Global Affairs about the Terrorist Attacks in Europe
An overview of the media appearances of scientists working with the Faculty of Governance and Global Affairs about terrorist attacks in Europe, their consequences, and more.
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Here is how we can increase the effectiveness of global environment protection
Researchers from the Institute of Environmental Sciences (CML) identified six top priorities where environmental interventions can make the most difference. By doing so, they hope to help researchers and policymakers make the most out of the limited, available resources to protect people and the pla…
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Global problems, local actions: Leiden professors help teachers, students and citizens to engage with environmental issues
In 2021, Thijs Bosker and Paul Behrens — both Associate Professors in Environmental Sciences at Leiden University — received funding from the Leiden University Fund and the Gratama Foundation to develop tangible and practical exercises that help people to deal with environmental issues from a local…
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Urgent shifts in building practices are needed to tackle the global sand crisis
A rapid increase in the demand for construction sand is driving shortages and inequality around the world. Researchers from the Institute of Environmental Sciences at Leiden University have mapped the growing need for sand, as well as the bottlenecks and possible solutions. They have published their…
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event of Pillar A of research programme Citizenship, Migration, and Global Transformations
On the past 6th of October, the Pillar A of the research program me Citizenship, Migration and Global Transformations finally had its awaited kick-off event, which was previously cancelled last spring due to the COVID-19 outbreak.
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Antoaneta Dimitrova
Faculty Governance and Global Affairs
a.l.dimitrova@fgga.leidenuniv.nl | +31 70 800 9500
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José María Castro Ibarra
Faculty of Humanities
j.m.castro.ibarra@hum.leidenuniv.nl | +31 71 527 1646
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Irma Mosquera Valderrama
Faculteit Rechtsgeleerdheid
i.j.mosquera.valderrama@law.leidenuniv.nl | +31 71 527 6618
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ILS conference on the European Union as a Global Actor in Maritime Security
On Thursday 25 and Friday 26 October 2018, the Europa Institute organized a conference within the framework of ‘Interaction between Legal Systems (ILS): Policing the High Seas’ and in cooperation with four Interest Groups of the European Society of International Law. The event brought together representatives…
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Flaws in the Flow: Investigating Gaps in the Governance of Post-Consumer Textile in the Netherlands
Workshop
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Matthias Haentjens and Jouke Tegelaar at the AFM on the European dimension of judicial review of financial supervision
Matthias Haentjens and Jouke Tegelaar held a presentation on the European dimension of judicial review of financial supervision at the Dutch Authority for the Financial Markets (Autoriteit Financiële Markten, AFM).
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interest: MARS staff exchange programme "Non-Western Migration Regimes in a Global Perspective"
Are you working at Leiden University and researching migration regimes outside of the Global North? Are you interested in doing fieldwork or a research visit at one of our partner universities? Then you might want to join the Leiden team of the EU funded Marie Curie Staff Exchange Network on non western…
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Identification of regulators of cancer - immune interactions
PhD defence
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Regulatory networks in Streptomyces
We aim to unravel the complex and intertwining regulatory systems that control development and antibiotic production in streptomycetes.
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Child rights expert sounds the alarm: ‘Global crises are hitting children hardest’
Wars, climate change and the effects of covid have caused a global decline in children’s well-being. In her inaugural lecture Ann Skelton, Professor of Children’s Rights in a Sustainable World, points to the disastrous effects of multiple interacting crises.
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participates in The International Forum on the Future of Constitutionalism Global Summit
The Global Summit, which took place from 12-16 January 2021, is an initiative by Richard Albert, the William Stamps Farish Professor in Law, Professor of Government, Director of Constitutional Studies at the University of Texas at Austin, and Founder & Director of the International Forum on the Future…