1,839 search results for “mathematical and statistical modelling” in the Public website
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Understanding membrane fusion at the molecular level using a biomimetic model system
How can the transport of molecules in living cells help to target medicines at exactly the right place?
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Enumeration and Simulation of Lattice Polymers as Models for Compact Biological Macromolecules
Promotores: H. Schiessel, G.T. Barkema
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Zebrafish embryos and larvae as a complementary model for behavioural research
Promotor: Prof.dr. M.K. Richardson
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Dirk van der Hoeven
Science
d.van.der.hoeven@math.leidenuniv.nl | +31 71 527 7146
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PKPD and disease modelling in therapy development for amyotrophic lateral sclerosis (ALS)
We aim to gain a better understanding of the natural disease progression of ALS in order to improve clinical trial design and analysis and to support drug discovery and clinical development of new drugs.
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Bart de Smit
Science
b.de.smit@science.leidenuniv.nl | +31 71 527 2727
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Jan-Hendrik Evertse
Science
evertse@math.leidenuniv.nl | +31 71 527 7148
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Ronald van Luijk
Science
rvl@math.leidenuniv.nl | +31 71 527 7147
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Robin de Jong
Science
rdejong@math.leidenuniv.nl | +31 71 527 4829
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Data Science and Artificial Intelligence (BSc)
The focus of the Bachelor Data Science & Artificial Intelligence is on computer science, and its applications in Artificial Intelligence. You will receive a strong basis in mathematics, statistics and computer science, combined with advanced knowledge of machine learning, cognitive science, human-robot…
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Seascape Corridors: How modelling routes through the sea can illuminate early island culture
What are the capabilities or limitations of traveling between islands and how does this reflect seasonal variation? Is it possible to show higher levels of connectivity between islands based on generated pathways between several sites on two separate islands?
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adaptability of β-lactamase: a study of inhibitor susceptibility in various model systems
β-Lactamases are enzymes that can break down β-lactam substrates, such as antibiotics, preventing the use of these antibiotics for the treatment of various infectious diseases. However, some compounds, β-lactamase inhibitors, can block these enzymes allowing for possible treatments using a combination…
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Gerard van Westen: 'Our model predicts what candidate drugs do in your body'
He’s a fast and animated speaker, which is only logical because Gerard van Westen is driving an express train. His destination? A virtual human, consisting of algorithms that predict what an administered substance will do in the body. The train is already a long way down the line and the pharmaceutical…
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A New Model of Global Governance in International Tax Law Making (GLOBTAXGOV).
Assessing the feasibility and legitimacy of the current model of global tax governance and the role of the OECD and EU in international tax law-making.
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Cultural evolutionary modeling of patterns in language change. Exercises in evolutionary linguistics
This thesis describes the use of the evolutionary approach in the study of language change, aiming to provide a better insight in the mechanisms that play a role in language change and to validate this approach in the field of language change.
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European Experts in Inflammation: from the molecular players to animal models and the bedside
How is inflammation in tuberculosis controlled by interplay between autophagy and inflammasome signalling?
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Zebrafish xenograft model: identification of novel mechanisms driving prostate cancer metastasis
Prostate cancer (PCa) is one of the most prevalent cancer in males.
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A monodromy criterion for existence of Neron models and a result on semi-factoriality
In the first part, we introduce a new condition, called toric-additivity, on a family of abelian varieties degenerating to a semi-abelian scheme over a normal crossing divisor.
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Innate immunity, developmental speed and their trade-offs in two hexapod models
This thesis focuses on important life history traits and their trade-offs using two hexapod models. Particularly, the trade-off between immune defense and embryonic developmental speed is a central theme of this study.
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Modelling the interactions of advanced micro- and nanoparticles with novel entities
Novel entities may pose risks to humans and the environment. The small particle size and relatively large surface area of micro- and nanoparticles (MNPs) make them capable of adsorbing other novel entities, leading to the formation of aggregated contamination.
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Flow through EMT Facilities Applying Dynamic Behavioral Simulation Models
This study aims to explore the use of a behavioral-design-based approach in simulating patient flow through EMTs. It provides a dynamic behavioral simulation model to assess the interactions between patients, staff members, and the related dynamic movements/interactions with the health care facility,…
- About this minor
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Organisation
The staff members of the Methodology & Statistics unit are members of various boards and committees.
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Training European experts in multilevel bioimaging, analysis and modelling of vertebrate development
How can novel bioimaging technologies and vertebrate model species be used to gain a better understanding of early cellular behaviours with the ultimate goal to increase our understanding of human development and disease processes?
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Our people
Some examples of AI-research done at Leiden.
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About the programme
The master's specialisation Methodology and Statistics in Psychology includes courses, a thesis and an internship. Teaching takes place in the form of seminars and small-group lectures and practicals, and is assessed primarily by written coursework and reports of empirical projects carried out individually…
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Bio-informatics lab
On the basis of the characteristic aspects of a picture, certain computers can tell us what the picture is showing. They can learn this in the same way that young children are able to learn to recognize images. Further improving these techniques opens the way to a whole range of new applications. Biology…
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United Nations Fellowship awarded to Statistics PhD Kevin Duisters
United Nations Global Pulse, an initiative of the UN Secretary-General on big data and AI, recently launched the Data Fellows program. Kevin Duisters, PhD in Statistics at the Mathematical Institute, was selected to take part in its first cohort of eight international students.
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Bayes and Networks
Promotor: A.W. van der Vaart
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Programme structure
The research specialisation offers you the opportunity to spend two full years on training in applied mathematics to become an independent scientist with a strong theoretical basis.
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Catherijne Knibbe
Science
c.knibbe@antoniusziekenhuis.nl | +31 71 527 6329
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Death of Mathematics student Willem Obbens
With dismay we took note of the sudden death of Willem Obbens, student and student assistant in Mathematics, Leiden University.
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Tense-Switching in Classical Greek A Cognitive Approach
The recently published book 'Tense-Switching in Classical Greek A Cognitive Approach' by Arjan Nijk provides classicists and linguists in general with a complete account of the 'historical present' in Classical Greek.
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Application of zebrafish and murine models in lipoprotein metabolism and atherosclerosis research
Cardiovascular diseases are still a major concern for the global health.
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Accurate modeling of the dynamics of dissociative chemisorption on metal surfaces
Fundamental understanding of molecular reactions on metal surfaces is important for improving heterogeneous catalysis.
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therapies for mitochondrial cardiomyopathies using advanced human stem cell models
PhD defence
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Modeling vascular disease using self-assembling human induced pluripotent stem cell derivatives in 3D vessels-on-chip
PhD defence
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Glucocorticoid signaling in a rat model of post-traumatic stress disorder
PhD defence
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Understanding and Targeting Coronaviruses Exploring advanced cell culture models and host-directed antiviral strategies
PhD defence
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Philipsprize for Mathematics to René Pannekoek
René Pannekoek received the 2013 Philipsprize for PhD students in Mathematics at the Dutch Congress for Mathematics 2013 in Nijmegen. It was the 8th time that this prize, 1000 Euro and a trophy, was awarded.
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Eiko Fried
Faculteit der Sociale Wetenschappen
e.i.fried@fsw.leidenuniv.nl | +31 71 527 2727
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Max van Haastrecht
Science
m.a.n.van.haastrecht@liacs.leidenuniv.nl | +31 71 527 4799
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Xaver Funk
Faculteit der Sociale Wetenschappen
s.x.funk@fsw.leidenuniv.nl | +31 71 527 2727
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Philips Mathematics Prize for Joost Batenburg
During the Dutch Mathematical Congress, Joost Batenburg has been awarded the Philips Mathematics Prize for PhD students.
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Multivariate Humanities
This case study-based textbook in multivariate analysis for advanced students in the humanities emphasizes descriptive, exploratory analyses of various types of data sets from a wide range of sub-disciplines, promoting the use of multivariate analysis and illustrating its wide applicability. Fields…
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Studying abstract mathematical equations using tangible surfaces
On January 5, Rosa Winter will obtain her doctorate in arithmetic geometry. She researched solutions of equations that define so-called ‘del Pezzo surfaces’. ‘I like geometry because I can imagine and draw the shapes and objects,’ says Winter. ‘That makes abstract mathematics feel more tangible.’
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Astrophysical plasma modeling of the hot Universe: Advances and challenges in high-resolution X-ray spectroscopy
Hot astrophysical plasma is ubiquitous in the Universe, from comets in our Solar system to the largest scale structures -- the cosmic web filaments. These hot plasmas, with the temperature of a few millions of degrees, are often observed in the X-ray wavelength range.
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Computational modeling of tumor growth and metastasis and the role of the immune system in tumor destruction
In this project, we aim to obtain a quantitative understanding of the role of the immune system in tumor regression, of the role of tumor cell heterogeneity in cancer growth and of tumor cell migration properties.
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Graphing algebraic formulas
Many students have difficulties to read and give meaning to algebraic formulas. In this study it is explored whether graphing formulas with pen and paper will improve students’ability to reason with algebraic formulas.
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Why Leiden University?
The Computer Science and SCS master specialisation gives you the opportunity to combine fundamental research in computer science with different aspects of science communication.