How can we help children and adults to acquire better reading comprehension? Paul van den Broek and his colleagues at the Brain and Education Lab are searching for an answer to this question by investigating reading and the related brain activity.

The infectious diseases malaria and tuberculosis are responsible for 2.1 million deaths every year. Leiden researchers are currently testing a new tuberculosis vaccine.

How does stress influence cognitive performance? What is the role of selective attention to threatening information in this effect? Could we prevent stress-induced decline of cognitive performance with pharmacological interventions? Could we use resting state theta/beta ratio as a biomarker for cognitive…

Promotor: P.D. Grünwald

The receptor nomenclature committee of IUPHAR, the International Union of Pharmacology, has several subgroups. Among these are a few that our division is involved in, those for adenosine, nicotinic acid, and GnRH receptors.

You can ask virtual assistant Siri about the weather, but you can’t have a real conversation with it yet. You can’t refer to anything that’s been said before, or ask the system why it says what it says. Stephan Raaijmakers, Professor by Special Appointment from TNO, hopes to change this.

Lipid signaling is an essential biological event/process in a plethora of pathophysiological conditions. The underlying idea of this thesis is that many of the roles and the complex interplay of the individual signaling lipids in inflammatory processes and related conditions in health and disease is…

This thesis explores different avenues to develop insurmountable antagonists for CC Chemokine Receptors, such as CCR1, CCR2 and CCR5.

This thesis investigates how non-genetic factors, such as inflammation and concomitant medication, impact hepatic drug metabolism and subsequent drug metabolizing phenotype predictions.

Political Scientist Valentina Carraro (Leiden University) devises a framework to assess the degree to which United Nations human rights bodies provide duplicating or contradicting recommendations to states. Focusing on the case of torture, she creates an original database of recommendations delivered…

This article devises a framework to assess the degree to which human rights bodies provide duplicating or contradicting recommendations to States. Focusing on the case of torture, it creates an original database of recommendations delivered to 14 countries in the years 2012–2016. Results show that duplications…

On Friday 7 March 2025 Adam Knight successfully defended a doctoral thesis and graduated.

There are numerous ways in which Asia and the West influence one another. Having a good understanding of the countries of Asia and their inhabitants improves the contacts between these two world regions. Leiden experts have studied Asia for decades from the perspective of different disciplines. Read…

If you could design your own education, how would you do it? That is what the students of the Bachelor Honours Class 'Rebuilding Education' asked themselves. The students were divided into five groups in which they designed workshops to improve education. They presented their workshops in December in…

The discussion on employability of higher education graduates has been around for several years, with more emphasis in the 21st century. Yet, universities are still challenged in the pursuit of providing work-ready graduates who can meet industry expectations.

L1-oral language education is widely regarded as essential for developing communicative competence and critical thinking. However, as a research domain it remains relatively underexplored. The aim of this study was to identify effective elements and challenges within oral language education and to contribute…

Cramming from a book, making notes or learning summaries. In the past these were about the only ways to memorise your course material. But that has long since changed. Multimedia is the code word. But is it effective?

Leiden University has an active open science community. Open science means transparency in all phases of research by precisely documenting every step of the way and making this publicly available. ‘It’s time to be open,’ say psychologists Anna van ’t Veer and Zsuzsika Sjoerds. There is increasing awareness…

Artificial intelligence systems are smart. They can recognize patterns better than humans, for example. Yet humans are still very much needed. How can you better steer those AI systems? LIACS lecturer Jan van Rijn wrote a book about this together with a number of colleagues. We asked him a few quest…

Professor of Catalysis and Surface Chemistry Marc Koper has been appointed as member of the Koninklijke Nederlandse Akademie van Wetenschappen (KNAW). 'Very honourable, I see this as a confirmation of my work,’ says Koper.

Artificial intelligence systems are smart. They can recognize patterns better than humans, for example. Yet humans are still very much needed. How can you better steer those AI systems? LIACS lecturer Jan van Rijn wrote a book about this together with a number of colleagues. We asked him a few quest…

Aske Plaat is the scientific director of LIACS, the Leiden Institute of Advanced Computer Systems. He is also an ambassador for Leiden University's LGBT+ Network. His enthusiasm shines through when he explains why.

With a grant from NWO, Thomas Hankemeier will develop new methods to better understand the dynamics of the building blocks of life, such as cells, enzymes, and metabolites. He does this together with the University of Amsterdam and a number of companies.

Dutch political party VVD wants to set up a 'Mini Schengen zone' to control immigration better. But that is easier said than done, says Professor of European Law, Jorrit Rijpma.

At the conference of the Honours College Science & Society, students present TED Talks on a social issue of their interest. ‘It brings together everything they have learned in the past two and a half years.’

Mohamed Tleis was born in Lebanon and studied there up to and including university. It was not an easy path because Tleis has to cope with a number of limitations: he has problems with both hearing and vision.

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Global problems such as diseases of affluence or microplastics in the sea are too complex to be dealt with from a single scientific discipline or by just one country. Leiden University has the expertise to bring solutions to these enormous problems a step closer. Read more in the research dossier on…

Women in the Middle Ages often wore better quality clothes than men. This is one of the conclusions drawn by Leiden archaeologist Chrystel Brandenburgh, who studied textile remnants from the period from 400 to 1000 A.D. PhD defence 10 May.

Potential drugs that seem promising in the lab, but don’t show any activity in a person: they cost the industry an incredible amount of time and money. That’s why Indira Nederpelt focuses on a more efficient search for new drugs in her PhD, by determining the kinetics of a potential drug earlier on…

Synthetic fuel is cleaner than natural oil, but its production process needs to be more efficient. Now for the first time, physicists have directly observed the molecules produced in the chemical process. This paves the way for designing more efficient catalysts. Publication on September 19th in Nature…

An international team of researchers, including Federico Calle-Vallejo of Leiden University’s Institute of Chemistry, have taken the atomic-scale design of catalysts to the next level. Their research contributes to the quest for a method to generate or store energy more efficiently. The report is published…

For medical research, researchers often recreate tissue in the lab. Organ-on-a-chip technology emulates organs, right down to the blood that flows through them, thus creating a realistic test model for drugs or research into disease processes. Researchers from the LUMC are coordinating an NWO Gravitation…

The League of European Research Universities (LERU) calls for greater appreciation of fundamental research that does not have an immediate application. A working group headed by Geert de Snoo, dean of the Leiden Faculty of Science, issued a memorandum on the subject on 29 August.

The availability of natural resources, the energy transition, the importance of circularity and our dependence on China. This and more is what Professor of Industrial Ecology René Kleijn's inaugural lecture is about.

The perfect ship is light and sleek for speed, but also needs to be strong and stable for safe sailing. These and other conflicting requirements make it difficult, even with a supercomputer, to find the ideal design. Computer scientist Roy de Winter has developed an algorithm that helps strike the perfect…

It is mostly rainfall and soil acidity that determine which microbes survive in a particular habitat and which do not. This knowledge is important for maintaining biodiversity. Leiden environmentalists contributed to the research. Publication in Nature on 1 August.

What clothing is best to buy if you want to consider the environment? That question isn't so easy to answer. You have to consider the entire life cycle of a garment: from production to the moment we dispose of it. In the segment 'What's better?' of the radio programme Living Planet, environmental scientist…

She develops algorithms that outperform leading optimization techniques and can be applied in many fields. For this work, Niki van Stein and her team have won the GECCO Humies Award. ‘With our method, we can create and refine algorithms for a wide range of applications—algorithms that are better than…

The European PANVIPREP research project started at the Leiden University Medical Center on 11 March. The participants are virologists, biochemists and pharmacists from 14 European countries. Their mission is to develop antiviral drugs to protect Europe during pandemics. At least two such antivirals…

Only one in five young people with emotional health problems such as an anxiety disorder receives appropriate professional help. GPs often fail to properly recognise the signals in children and young people, according to psychologist Semiha Aydin. How can we improve this? PhD defence 23 February.

Rapid developments in DNA techniques allow researchers to find out more and more about human genetics. An international group of scientists has drawn up five ethical guidelines to ensure that this DNA research is better regulated. Leiden archaeologist Marie Soressi – one of the signatories - explains…

Exceptional collaboration between physicians is needed to better understand and treat autoimmune diseases that cause inflammation in various organ systems.

Researchers at Leiden University and TU Delft have combined two techniques that are used to measure the structure of biomolecules, creating a method that is ten times more sensitive.

On 17 November, the European academic community will be a partnership richer, when EUniWell, the European University of Well-Being, is launched. Within EUniWell, Leiden University and six other universities are working together on well-being challenge. Four Leiden researchers explain the benefits of…

There is certainly some variation in terms of pupils’ performance and motivation. This is evident from the GUTS teaching innovation project conducted by education specialist Lindy Wijsman in the first three classes at a secondary school in Rotterdam. In the first three years, the level of pupils’ performance…

Where exactly on the surface of a catalyst do the chemical reactions occur? Until now, it has always been a challenge to identify the exact locations of these ‘active sites’. In a new article in Nature, Leiden chemists helped their international colleagues reveal new insights into this issue. Their…

Leiden University has published a research report on the working of the Temporary Act on the Transparency of Fast-track Liquidation in the Netherlands. The Act aimed to facilitate faster and more transparent business termination. Has this been achieved?

Doğukan Yilmaz chose a study that aligned with his favourite subjects, and it paid off. For his bachelor thesis, he developed a new model to better predict an important chemical reaction. ‘On the edge of what is possible at the bachelor level,’ his supervisors write. Thanks to his impressive achievements,…

More than 200 students completed their Bachelor’s degrees in combination with a three-year Honours programme last year. On 15 November, this resulted in a record number of certificates since the start of the Honours College 9 years ago. While listening to personal speeches, the students received their…