In this project, we aim to obtain a quantitative understanding of the role of the immune system in tumor regression, of the role of tumor cell heterogeneity in cancer growth and of tumor cell migration properties.

Prostate cancer (PCa) is one of the most prevalent cancer in males.

In the first part, we introduce a new condition, called toric-additivity, on a family of abelian varieties degenerating to a semi-abelian scheme over a normal crossing divisor.

Novel entities may pose risks to humans and the environment. The small particle size and relatively large surface area of micro- and nanoparticles (MNPs) make them capable of adsorbing other novel entities, leading to the formation of aggregated contamination.

This dissertation explores various perspectives on the term immersion, and its relation with, and transformation through, a composer’s practice.

Taal als sleutel tot het begrijpen van de mens.

The multidisciplinary minor The (Un)just Society explores social justice in the Netherlands. You examine issues such as poverty, discrimination, housing shortages, climate, and migration from various perspectives. Through practical assignments and reflection on your own role in society, you actively…

Marine Le Pen, an immensely popular French politician, has been found guilty of misappropriating EU funds and is barred from running for public office for five years. Wim Voermans, Professor of Constitutional Law, commented on her conviction in ‘Bar Laat’.

The LUCAS Institute has both a new Scientific Director and a new Education Director. Stijn Bussels and Esther Op de Beek both commenced their new roles at the start of the academic year.

Promotor: A.H. Meijer, Co-promotor: B.E. Snaar-Jagalska

On 17 October 2018, Henriëtte Weststrate defended her doctoral thesis 'De Notaris en Private Rechtspraak'. The doctoral research was supervised by Prof.dr. H.J. van der Herik and Prof. mr. G.J. Meijer.

Om de verkeersveiligheid te kunnen waarborgen en overlast in de binnenstad tegen te gaan, wil de gemeente Enschede als eerste gemeente in Nederland een verbod op fatbikes invoeren. Geerten Boogaard, hoogleraar decentrale overheden, zegt in RTL-nieuws vraagtekens te hebben bij de juridische haalbaarheid…

On Friday morning, 18 October, Rector Magnificus Hester Bijl and Professor Remco Breuker welcomed Korea Foundation President Gheewan Kim.

Dr. Pauline Aarten onderzoekt welke impact een verkeersongeval heeft op slachtoffers en nabestaanden en hoe we de positie van deze mensen kunnen verbeteren.

Huub de Groot is professor in Biophysical Organic Chemistry. With his team he works in the field of photosynthesis and artificial photosynthesis. The molecular basis for photosynthesis is formed by protein complexes and organelles that contain chlorophyll molecules. The antenna systems herein capture…

Reijer Passchier, universitair docent Staatrecht in Leiden en hoogleraar Digitalisering en de democratische rechtsstaat aan de Open Universiteit, pleit voor de ontwikkeling van europese techbedrijven, waarbij europa zijn soevereiniteit weet te behouden. Hij waarschuwt vooral niet het ‘destructieve gigantisme-model…

Our group explores the larger domain of quantum measurement. In particular we investigate two themes that are closely connected: The detection of specially prepared quantum states of light and understanding and characterizing quantum photon detectors.

On 12 January 2022, Mirjam Franke defended the thesis 'Over de grens van de onrechtmatige daad'. The doctoral research was supervised by Prof. A.G. Castermans and Prof. J.H. Crijns.

On 25 November 2018, Laurens de Hoog defended his thesis 'De prioriteitsregel in het vermogensrecht'. The doctoral research was supervised by Prof. mr. W.G. Huijgen.

‘The storm of the passions rages’: The works of Johannes Jelgerhuis as a source of stagecraft for the historically informed performer.

This dissertation provides a formal description of the relationship between diatopic/diachronic micro-variation and phonologization through analysis of the phonetic/phonological properties of unstressed vowel reduction and vowel insertion in two Northern Italian dialects.

In this paper, the authors outline how the UK and USA adopt the Chilean pension model without proper attribution, potentially distorting the lessons.

The objective of this project is the development of a new psychometric model, called the Generalized Squared Distance Logistic Model (GSDLM). This model is an evolution of older psychometric approaches (such as PARELLA, GHCM, and GGUM) and the Gaussian Ordination Models (GOMs) used in environmental…

The aim of this thesis is to present novel techniques for proving cryptographic schemes secure against quantum adversaries. Most results are within the context of an idealized model called the ‘quantum random-oracle model’.

PhD defence

This research project adresses the question how local and traditional European forms of parrhesiastic theater— events, actions, and performances staged by characters who courageously speak their minds through scenes of excess and laughter, that take place in public view and incite the spectator’s agency…

PhD defence

Cholesterol influences many pathways, including serving as precursor for adrenal steroidogenesis. Imbalance of cholesterol levels has been implicated in several diseases including cardiovascular diseases and its underlying pathology, atherosclerosis.

This dissertation addresses the different use of the same philosophical model: immanent teleology. In this work Aristotle, the founder of the study of final causes, is put in relation with the modern French evolutionary thinker Henri Bergson, the philosopher of time. The dissertation tackles the two…

The Repository from the Drug Disease Model Resources (DDMoRe) consortium provides a home to a collection of computational models of disease and drug action that have been used in pharmaceutical and/or academic research. This publically available open-access resource will make it easier for researchers…

We use zebrafish as a model organism to study human development and disease as well as animal welfare and environmental impact.

Clearance is the most important pharmacokinetic parameter for drug dose selection. Pharmacokinetic information is typically first available in the adult population, and in general only limited pharmacokinetic data are available in children when drugs enter into the market. It is therefore of the utmost…

Discover the new MSc in Public Sector Economics at Leiden University, offered entirely in Dutch. This program prepares future policy economists by bridging economic theory, Dutch institutions, and real-world policy challenges. Starting September 2025 in The Hague, it focuses on key issues like inequality,…