2,743 search results for “development disease” in the Public website
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In conversation with the head of the rodent facility
Before patients can take a pill, scientists often spend years in the lab developing and testing a candidate drug. That often includes experiments with laboratory animals. As head of the rodent facility, Ilze Bot and her colleagues ensure that these experiments are conducted in an ethically responsible…
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Influencing your health with your behaviour and thoughts
Psychological processes have a major effect on the course of a disease and the effects of medical treatment. Researchers in the field of Psychoneurobiology examine the interactions between body and mind. They investigate the effects of stress as well as the effect of placebos and nocebos, which can…
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PhD candidates in their own words
The Data Science Research Programme at Leiden University combines data science with PhD projects in a wide range of disciplines. The programme has been running for over two years, and is producing the first astonishing results. A number of PhD candidates talk about their experiences and research bel…
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Unequal Land Relations in North East India: Custom, Gender and the Market
Presenting case studies by both senior and emerging scholars, it makes mandatory reading for anyone interested in the challenges of governance, citizenship and development faced by the people of India’s North East.
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Support Departments
List of Support Departments at LION and the Faculty of Science
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Chemical Biology & Immunology
The Chemical Biology & Immunology (CBI) group is headed by Prof. Sander van Kasteren and Prof. Kim Bonger.
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Health and Medical Psychology (MSc)
In the specialisation Health and Medical Psychology, part of the Master in Psychology, you will acquire knowledge on clinical and scientific topics in health promotion and disease prevention as well as practical training on clinical skills and behaviour change.
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NWO-XS Grants for Psychology Researchers
Researchers Marit Ruitenberg and Janna Marie Bas-Hoogendam have received NWO-XS grants for their research projects on freezing in Parkinson’s disease and the neurobiology of social anxiety. The grant supports innovative, curiosity-driven research within the social sciences and humanities.
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Child care
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Research
Research at the BIOSYN group is comprised of the following research themes:
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Advanced non-invasive diagnostics in congenital heart disease
PhD defence
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Evolutionary adaptability of β-lactamase: a study of inhibitor susceptibility in various model systems
β-Lactamases are enzymes that can break down β-lactam substrates, such as antibiotics, preventing the use of these antibiotics for the treatment of various infectious diseases. However, some compounds, β-lactamase inhibitors, can block these enzymes allowing for possible treatments using a combination…
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Historical and Linguistic Development of the Signing Community in Mozambique: The Emergence of local sign through contact, influence and linguistic
This PhD project investigates the historical and sociolinguistic factors that have influenced the emergence of local sign languages in Mozambique. It examines how these factors have shaped the Deaf signing community and contributed to the development of a national sign language that incorporates borrowings…
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Java: the role of indigenous institutions in integrated elderly care development in Indonesia
This research delves into the unique cultural approach of the Tenggerese people, an Indigenous community in East Java, Indonesia, regarding elderly care. It focuses on their traditional practices of bakti (‘filial piety’) and sayan (‘mutual aid’), deeply ingrained in the community's lifestyle and va…
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Leiden University and ICTU start research on software development
How can we further streamline the development of software for the government? Leiden University and ICTU are to investigate this in a joint research project that was launched on 6 July 2016.
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Research
Leiden University is an international, broad-based university. We distinguish five core domains for our research and teaching activities.
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Talks
Five talks will be given during the Leiden Science Family Day: two children's lectures and three lectures for adults. Will you be there ?
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Exposed to events that never happen: Genaralized unsafety and prolonged psysiological stress responses
The aims of the project are to: further clarify 'inhibition by safety'; explore and describe all possible sagety factors, with a special focus on the primary human safety source: social connectedness; reviewing prolonged stress responses without stressors.
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Unwiring beneficial functions and regulatory networks in the plant endosphere
How do plants lure microscopically small 'support teams' into their roots for protection against diseases? And what functions are activated in the microbes and the plants?
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Illuminating Host Defence against Mycobacterial Infection: Interactions with Autophagy and LC3-Associated Phagocytosis
Despite substantial progress in understanding tuberculosis (TB), the eradication of the TB epidemic is still far from reach.
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Health and well-being in a healthy society
The theme 'Health and well-being in a healthy society' is one of the focal points of the Faculty of Social and Behavioural Sciences (FSW). We are committed to promoting health and well-being for people of all ages.
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Discoverer of the Year bridges science and medicine
Fascinated by science since high school, Alireza Mashaghi Tabari is driven to explore new ways of thinking in medicine. With a strong academic network, he educates students and gives public lectures. For his research at LACDR, he won the C.J. Kok Public Award 2018, making him the Faculty of Science's…
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FAQ research with animals
Antwoord op veelgestelde vragen over onderzoek met proefdieren bij de Universiteit Leiden. FAQ
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Blood vessels on a chip make the cause of dementia visible
New technology offers many new possibilities for research, such as on dementia. ‘Organ-on-a-chip’ is a new technology in which small bits of organ are grown out of stem cells on a small plastic plate. A small piece of blood vessel, heart or nerve offers many new possibilities for research, such as…
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Chemical genetic approaches for target validation
Drug development is a time- and resource-consuming process that starts with the discovery and validation of a (protein) target that contributes to pathogenesis or disease progression.
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Shielding software systems: A comparison of security by design and privacy by design based on a systematic literature review
The authors systematically search and review relevant definitions of Security by Design (SbD) in comparison with Privacy by Design (PbD).
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Archaeological Sciences
With the emergence of new methods and technologies such as improved DNA analysis and big data, archaeological research has changed radically in recent decades. The researchers from the Department of Archaeological Sciences at the Faculty of Archaeology use new scientific knowledge to answer fundamental…
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Prestigious Edinburgh Medal awarded for ‘Astronomy for Development’
The Edinburgh Medal 2016 had been awarded to both Kevin Govender of the Office of Astronomy for Development (OAD) and the International Astronomical Union (IAU). The award is a recognition for furthering education and technological capacity worldwide through the inspirational science of astronomy. The…
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Minor Sustainable Development
Make a difference! Join the interdisciplinary Minor Sustainable Development and learn everything about the challenges we are facing and how to find solutions. Discover your sustainable future!
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Richard Karlsson Linnér: ‘I expect a future where a genetic test will be as much a no-brainer as getting X-rayed.’
Assistant Professor Karlsson Linnér, who works at the Department of Economics, is one of the recipients of a Veni grant. His research on the accuracy of preventive genetic testing is a fine example of the intersection of economic science and law.
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Major international study links genes to brain structural changes over time
There seem to be genes that influence how our brains develop over time. A large international consortium has discovered this with an extensive study. The results of the study were recently published in Nature Neuroscience.
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Research ecosystem
The chain that supplies patients with new medicines consists of various complex links: from fundamental research to clinical tests and production. This entire chain is represented in Leiden. Leiden University, the Leiden University Medical Center (LUMC), and the companies on the Leiden Bio Science Park…
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B cell modulation in atherosclerosis
Cardiovascular disease is a major global burden and atherosclerosis is the main underlying pathological process.
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New clue to severe MS progression: ‘Overloaded cleanup cells’ in the brain
Researcher Daan van der Vliet, together with colleagues from the Netherlands Institute for Neuroscience, Leiden University and Utrecht University, has discovered an important mechanism that may be linked to severe cases of multiple sclerosis (MS): the brain contains large numbers of abnormal immune…
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Hoko HoriiFaculteit der Rechtsgeleerdheid
h.horii@law.leidenuniv.nl | 071 5277260
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John van Noort Lab - Chromatin Dynamics
Chromatin is an ubiquitous protein-DNA complex that forms the structural basis of DNA condensation in all eukaryotic organisms.
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Replacing the needle and syringe for vaccine administration
Promotores: Prof.dr. G.F.A Kersten, Prof dr. J.A. Bouwstra
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Reading the Dental record
A dental anthropological approach to foodways, health and disease, and crafting in the pre-Columbian Caribbean.
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Strategy
The research area of this division is focused on the development of novel therapeutic modalities and novel concepts in early drug discovery, in order to better predict ligand-target interactions.
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Natural and non-natural factors influencing Alzheimer´s Aβ
Promotor: Prof.dr. J.P. Abrahams
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Application of zebrafish and murine models in lipoprotein metabolism and atherosclerosis research
Cardiovascular diseases are still a major concern for the global health.
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Monounsaturated fatty acids reduce the barrier of stratum corneum lipid membranes by enhancing the formation of a hexagonal lateral packing
The effectiveness of the skin barrier underlies the outer layer of the skin: the stratum corneum (SC). However, in several skin diseases this barrier is impaired. In two inflammatory skin diseases, atopic eczema and Netherton syndrome, an increased level of monounsaturated fatty acids (MUFAs) has been…
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Martin Giera
Assistant Professor at the Metabolomics group, LUMC, The Nederlands
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Force sensing and transmission in human induced pluripotent stem-cell-derived pericytes
Pericytes, the mural cells of blood microvessels, are important regulators of vascular morphogenesis and function that have been postulated to mechanically control microvascular diameter through as yet unknown mechanisms.
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Anticipatory Grief in Dementia: An Ethnographic Study of Loss and Connection
Natashe Lemos Dekker addresses the experiences of family members of people with dementia as they expressed their sense of gradually losing the person with dementia in the article 'Anticipatory Grief in Dementia: An Ethnographic Study of Loss and Connection' published in Culture, Medicine, and Psychi…
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Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity, Nat. Commun., 2017
The cannabinoid CB2 receptor (CB2R) represents a promising therapeutic target for various forms of tissue injury and inflammatory diseases. Although numerous compounds have been developed and widely used to target CB2R, their selectivity, molecular mode of action and pharmacokinetic properties have…
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Topic: Work and health
The research connected to this topic is related to Work and health.
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System-level design for efficient execution of CNNs at the edge
A convolutional neural network (CNN) is a biologically inspired algorithm, highly capable at processing images and videos.
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Mechano-transduction mediated by integrin-based adhesion complexes: integration of cytoskeleton and adhesion dynamics
In this thesis, we focus on novel proteins/mechanisms that regulate integrin-adhesion mediated mechano-transduction.
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Hypermarker
Developing a clinical decision support tool that will make it easier for clinicians to personalise the treatment for patients with high blood pressure. The team is using AI, deep learning methods and patient cohort data from 11 European countries.