Horses were first domesticated in South-West Russia, is the conclusion drawn by an international team of researchers writing in the well-respected journal Nature. Their conclusion resolves a longstanding archaeological question. But, surprisingly enough, this domestication did not contribute to the…

Lions in West and Central Africa form a unique group, only distantly related to lions in East and Southern Africa. Biologists at Leiden University confirm this in an article published in Scientific Reports.

Promotor: E. Gittenberger, Co-promotor: B.W. Hoeksema

We aim to unravel the molecular mechanisms involved in the transformation of eukaryotic cells by Agrobacterium.

The molecular mechanisms that instigate a healthy cell to become malignant are fueled by (epi)genetic alterations in so-called driver genes.

Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.

Assistant Professor Karlsson Linnér, who works at the Department of Economics, is one of the recipients of a Veni grant. His research on the accuracy of preventive genetic testing is a fine example of the intersection of economic science and law.

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Streptomyces are multicellular, Gram-positive bacteria in the phylum of actinobacteria which produce a high amount of bioactive natural products of which the expression is tightly coordinated with the life cycle.

The role of language in self-regulation and social behavior in children with an extra X chromosome

PhD defence

The clinical potential of applying synthetic lethality to cancer treatment is famously demonstrated by the BRCA1/PARP1 paradigm: a tumor specific defect in BRCA1 – a component of the DNA double-strand break (DSB) repair pathway homologous recombination (HR) – results in a remarkable sensitivity to PARP1…

Social anxiety runs in families, but the neurobiology underlying this genetic vulnerability is until now largely unknown. The unique Leiden Family Lab study on Social Anxiety Disorder (LFLSAD) aims to broaden our knowledge with respect to this genetic susceptibility.

The aim of the project is to unravel the genetic and contact relations between the indigenous languages of Mesoamerica (Mexico and western Central America) and the Middle Andes region (Ecuador, Peru, Bolivia), as part of a larger endeavor to understand the historical process of the peopling of the Americas…

Animal diet studies are critical for understanding ecological processes such as trophic interactions, energy flow, and nutrient cycling. By examining what animals consume, ecologists gain insights into species specialization, predator-prey relationships, and ecosystem management.

Supervisor: P.J.J. Hooykaas Co-Supervisor: R. Offringa

This longitudinal study is focused on neurodevelopmental problems in young children with XXY, XXX and XYY, aged 1 to 6 years.

PhD defence

Insect egg development in a warming world: the eco-evo-devo of embryonic developmental time: What is the genetic basis of developmental time?

PhD defence

Getting personal

Promotor: Prof.dr. M. Danhof, Co-Promotor: J. de Jongh

Promotor: P. J. J. Hooykaas, Co-promotor: R. Offringa

Organisms often need to adapt more efficiently and devise new strategies for surviving difficult ecological circumstances.

Challenges for the protection of traditional knowledge and genetic resources, traditional cultural expressions, and traditional knowledge of indigenous peoples in the international scenario.

Do you have questions about the master’s specialisation Molecular Genetics and Biotechnology? Please contact us.

Up to 45% of patients with Parkinson's disease experience impulse control disorders, characterised by a loss of voluntary control over impulses, drives or temptations. This study aimed to investigate whether previously identified genetic and psychiatric risk factors interact towards the development…

Find out how to apply for Molecular Genetics and Biotechnology at Leiden University by following our step-by-step guide.

Lecture, Tuesday Talks: Science Insights

Brain development in children with an extra X chromosome as compared to children with autism: evidence from MRI

Promotores: J. Jonkers, K.E. de Visser

Lecture, Comparative Indo-European Linguistics (CIEL) Seminars

Hybrid zones occur where two species meet and produce offspring (hybrids). Typically, hybrids show a considerable reduction in fitness. In this thesis two hybrid zones are treated.

Research in the group Clinical Neurodevelopmental Sciences is focused on understanding and influencing developmental mechanisms in children and adolescents.

Lysosomal storage disorders (LSDs) are a group of orphan diseases characterized by lysosomal dysfunction or impaired lysosomal catabolism and affect collectively about 1 in 5000 live births.

Source: Biosens Bioelectron, Volume 74, pp. 233-42 (2015)

Promotor: P. J. J. Hooykaas Co-promotor: B. S de Pater

We perform multidisciplinary research at molecular, cellular, and organismal levels of animal biology to increase fundamental understanding of health and disease.