Anja Groten investigates matters of collectivity, drawing from the experience of working with the Amsterdam-based collective Hackers & Designers (H&D)*.

This dissertation explores matters of collectivity, drawing from the experience of working with the Amsterdam-based collective Hackers & Designers (H&D).

The aim of this study was to provide insight into how teachers in higher education can be supported in the design, implementation and evaluation of group assignments by developing a theoretical and evidence-based framework for the design of group assignments.

The new book by Dimiter Toshkov - associate professor of Public Administration at the Faculty of Governance and Global Affairs - has been recently published by Palgrave Macmillan.

DSE 2.0 concerns research on DSE techniques for complex dCPS

The increasing competition in the automotive industry requires the tailored, swift development of technologically sophisticated vehicles. Therefore, the computationally expensive state-of-the-art simulation technologies are combined with optimization algorithms. An example of a real-world optimization…

Constraint multi-objective optimization with a limited budget for function evaluations is challenging. This thesis tackles this problem by proposing new optimization algorithms. These algorithms are applied on holistic ship design problems. This helps naval architects balance objectives like cost, efficiency,…

In order to analyze the challenges linked to data use in the context of nexus governance, Giest & Mukherjee use a policy design lens and more specifically the perspective of organizational policy instruments to look at the Mediterranean region.

Glycosidases are essential in fundamental biological processes and are responsible for the degradation of most (oligo)saccharides, glycolipids and glycoproteins.

How can the Safe and Sustainable by Design (SSbD) framework developed in the SSbD4CheM project facilitate the creation of safer and more sustainable chemicals and materials across various industries?

The thesis describes the development, synthesis and biological evaluation of several proteasome inhibitor designs. Mainly, this work focusses on designing proteasome inhibitors that selectively inhibit the immunoproteasome, while leaving the constitutive proteasome mostly, if not completely, untouch…

How to deal with the most challenging design question of your life: what do I want to be when I grow up? The ‘Designing Your Life’ method teaches students how to craft their own future. The project will start next academic year, thanks to a Comenius grant. ‘Everyone interested should be able to borrow…

The main subject of this thesis is the design and synthesis of paramagnetic molecules for protein studies with NMR and EPR spectroscopy.

In design optimization problems, engineers typically handcraft design representations based on personal expertise, which leaves a fingerprint of the user experience in the optimization data. Thus, learning this notion of experience as transferrable design features has potential to improve the performance…

Promotores: Prof.dr. T.H.W. Bäck, Prof.dr. M.R.V. Chaudron, Co-Promotor: M.T.M. Emmerich

What are the characteristics of impactful education for student application of inclusive design principles in design and technology programs?

Optimally solving real-world expensive Black-Box Optimization (BBO) problems w.r.t. real-world constraints, such as wall-clock time and computational costs, is extremely difficult and tedious.

How do we approach education that facilitates creative confidence for students that leads to innovative solutions to society’s present day and future sustainability challenges? This education research project tackles a sustainability dilemma faced by households in everyday life viz.

A convolutional neural network (CNN) is a biologically inspired algorithm, highly capable at processing images and videos.

This thesis describes the design, synthesis, and immunological evaluation of varying (neo)antigenic peptide conjugates containing either a TLR2 or a TLR7 agonist.

Over several decades, a variety of computational methods for drug discovery have been proposed and applied in practice. With the accumulation of data and the development of machine learning methods, computational drug design methods have gradually shifted to a new paradigm, i.e. deep learning methods…

Whilst government’s ability to design ‘context-specific’ regional innovation policy is generally assumed to depend on the region’s decision-making power, the aim of this study is to investigate how regional government matters. In order to open up the black box of policy design, the study develops a…

The first index to measure product safety, sustainability, and circularity, operationalising the EU’s (SSbD) framework.

Utilizing the polymeric platform of polypept(o)ides, this thesis describes synthesis and investigation of novel triblock copolymers to obtain carrier systems with multiple compartments for efficient siRNA delivery. Although the individual microstructure of nanoparticles differs depending on the polymeric…

Promotores: Prof.dr. G. Miley & Prof.dr. J.M. van den Broek

Atherosclerosis is a chronic inflammatory disease affecting millions of people world-wide.

In September 2023, we started transforming a under-utilised outdoor space into a greener and more biodiverse garden in which all students and staff of the Schouwburgstraat can relax and enjoy.

The central issue of this research concerns how students can best be supported in their study choice, study career and future orientation with a view to flexible entry and transitions and perspective in education and work.

Tuberculosis is an infectious disease which is spreaded through the air. It is caused by Mycobacterium tuberculosis and it led 1.7 million people to death in 2016. This mortarlity rate is concentrated in developing countries such as Indonesia, Philippines, Pakistan, and South Africa. These numbers make…

Glycoside hydrolases (glycosidases/GHs) are widely abundant enzymes in all kingdoms of life and are important biocatalysts that catalyze the hydrolysis of glycosidic linkages in oligo/polysaccharides, glycoproteins and glycolipids with tremendous efficiency

Electoral Systems and Turnout: Evidence From a Regression Discontinuity Design. In this article, published on the website SAGE research methods, authors Jaroslaw Kantorowicz and Tobias M. Hlobil discuss how a Regression Discontinuity Design can be executed.

Technologies that help to enhance our educational environments can be found everywhere.

Research in and through art is an inseparable part of the artistic or design practice of the researcher. Consequently, research-in-art (as opposed to research-about-art, such as art history) does not have a set goal or expected result, nor are there predetermined general procedures. The outcome of the…

The Lectorate Design at the KABK explores the research method of walking from a design perspective, and features the working process used by public space and landscape designers Krijn Christiaansen and Cathelijne Montens (KCCM) who teach field research in BA Interior Architecture and Furniture Design…

On December 16th 23 students of the Institute of Environmental Sciences of Leiden University took part of the first total species inventory to assess the effectiveness of an underwater landscape that was build in March 2003 to restore the biodiversity in an area where the environment was destroyed by…

The Institute of Electrical and Electronics Engineers (IEEE) appointed Professor Thomas Bäck as an IEEE Fellow in the class of 2022. Bäck is becoming a Fellow for his contributions in synthesising evolutionary computation. Less than 0.1% of voting members are selected each year for this member grade…

The Green Office wants to help start a community garden in the open patio space of the Schouwburgstraat buiding in the Hague.

Since the end of the nineteenth century Arabic book designers have influenced the social and cultural situation in the Middle East with their work. Huda Smitshuijzen Abi-Farès has written the first global overview of this neglected field of science. PhD defence 10 January.