This dissertation explores matters of collectivity, drawing from the experience of working with the Amsterdam-based collective Hackers & Designers (H&D).

e-SIDES (ethical and societal impact of data sciences) is a Coordination & Support Action (CSA) part of the Horizon 2020 programme.

The aim of this study was to provide insight into how teachers in higher education can be supported in the design, implementation and evaluation of group assignments by developing a theoretical and evidence-based framework for the design of group assignments.

The new book by Dimiter Toshkov - associate professor of Public Administration at the Faculty of Governance and Global Affairs - has been recently published by Palgrave Macmillan.

DSE 2.0 concerns research on DSE techniques for complex dCPS

The increasing competition in the automotive industry requires the tailored, swift development of technologically sophisticated vehicles. Therefore, the computationally expensive state-of-the-art simulation technologies are combined with optimization algorithms. An example of a real-world optimization…

Constraint multi-objective optimization with a limited budget for function evaluations is challenging. This thesis tackles this problem by proposing new optimization algorithms. These algorithms are applied on holistic ship design problems. This helps naval architects balance objectives like cost, efficiency,…

In order to analyze the challenges linked to data use in the context of nexus governance, Giest & Mukherjee use a policy design lens and more specifically the perspective of organizational policy instruments to look at the Mediterranean region.

Glycosidases are essential in fundamental biological processes and are responsible for the degradation of most (oligo)saccharides, glycolipids and glycoproteins.

The thesis describes the development, synthesis and biological evaluation of several proteasome inhibitor designs. Mainly, this work focusses on designing proteasome inhibitors that selectively inhibit the immunoproteasome, while leaving the constitutive proteasome mostly, if not completely, untouch…

The main subject of this thesis is the design and synthesis of paramagnetic molecules for protein studies with NMR and EPR spectroscopy.

In this research project, the protection of personal data is compared in eight EU member states: France, Germany, the UK, Ireland, Romania, Italy, Sweden and the Netherlands. The comparison of the countries is focused on government policies for the protection of personal data, the applicable laws and…

In design optimization problems, engineers typically handcraft design representations based on personal expertise, which leaves a fingerprint of the user experience in the optimization data. Thus, learning this notion of experience as transferrable design features has potential to improve the performance…

Promotores: Prof.dr. T.H.W. Bäck, Prof.dr. M.R.V. Chaudron, Co-Promotor: M.T.M. Emmerich

What are the characteristics of impactful education for student application of inclusive design principles in design and technology programs?

Optimally solving real-world expensive Black-Box Optimization (BBO) problems w.r.t. real-world constraints, such as wall-clock time and computational costs, is extremely difficult and tedious.

How do we approach education that facilitates creative confidence for students that leads to innovative solutions to society’s present day and future sustainability challenges? This education research project tackles a sustainability dilemma faced by households in everyday life viz.

This thesis describes the design, synthesis, and immunological evaluation of varying (neo)antigenic peptide conjugates containing either a TLR2 or a TLR7 agonist.

The Ministry of Health seems to be going full steam ahead in the search for a track-and-trace app to contain the coronavirus crisis. The apps are being developed with irresponsible haste, according to Valerie Frissen, Professor of Digital Technologies and Social Change.

Over several decades, a variety of computational methods for drug discovery have been proposed and applied in practice. With the accumulation of data and the development of machine learning methods, computational drug design methods have gradually shifted to a new paradigm, i.e. deep learning methods…

Whilst government’s ability to design ‘context-specific’ regional innovation policy is generally assumed to depend on the region’s decision-making power, the aim of this study is to investigate how regional government matters. In order to open up the black box of policy design, the study develops a…

Utilizing the polymeric platform of polypept(o)ides, this thesis describes synthesis and investigation of novel triblock copolymers to obtain carrier systems with multiple compartments for efficient siRNA delivery. Although the individual microstructure of nanoparticles differs depending on the polymeric…

Promotores: Prof.dr. G. Miley & Prof.dr. J.M. van den Broek

Atherosclerosis is a chronic inflammatory disease affecting millions of people world-wide.

You are warmly invited to join us for the second meeting of the KABK Design / Research Club, a forum for researchers from the KABK and Leiden University who are conducting research in, about, or through design-related disciplines.

Those who know their dystopian classics will inevitably associate the concept of surveillance society with the all-knowing oppressive force characterized as Big Brother in George Orwell’s novel 1984. However, surveillance permeats our society in many more subtle aspects than our worst fears about spy…

The central issue of this research concerns how students can best be supported in their study choice, study career and future orientation with a view to flexible entry and transitions and perspective in education and work.

Eduard Fosch Villaronga, Assistant Professor at eLaw, co-organised together with Aurelia Tamò-Larrieux, Christoph Lutz, Anton Fedesov, and Anto Čartolovni the GoodBrother International Conference on Privacy-friendly and Trustworthy Technology for Society on 28 June 2022 in Zagreb, Croatia.

Although the General Data Protection Regulation (GDPR) harmonizes the protection of personal data across the EU as of May 2018, its open norms in combination with cultural differences between countries result in differences in the practical implementation, interpretation and enforcement of personal…

Tuberculosis is an infectious disease which is spreaded through the air. It is caused by Mycobacterium tuberculosis and it led 1.7 million people to death in 2016. This mortarlity rate is concentrated in developing countries such as Indonesia, Philippines, Pakistan, and South Africa. These numbers make…

Glycoside hydrolases (glycosidases/GHs) are widely abundant enzymes in all kingdoms of life and are important biocatalysts that catalyze the hydrolysis of glycosidic linkages in oligo/polysaccharides, glycoproteins and glycolipids with tremendous efficiency

Electoral Systems and Turnout: Evidence From a Regression Discontinuity Design. In this article, published on the website SAGE research methods, authors Jaroslaw Kantorowicz and Tobias M. Hlobil discuss how a Regression Discontinuity Design can be executed.

Privacy continues to keep the attention: from MeToo! to Facebook. The legal magazine 'Ars Aequi' has published a special issue 2019 dedicated to the concept of Privacy. Three contributions originate from eLaw, the center for Law and Digital Technologies at the Faculty of Law.

Starting four years ago, the same privacy laws apply throughout the European Union: the General Data Protection Regulation (GDPR). The law also affects our work at the university. As a refresher, we spoke with Privacy Officer Max van Arnhem about privacy in the workplace and what to do if something…

Technologies that help to enhance our educational environments can be found everywhere.

How to strike a balance between the sometimes conflicting stakes of individual, public and private data-producers and data-processors?

Research in and through art is an inseparable part of the artistic or design practice of the researcher. Consequently, research-in-art (as opposed to research-about-art, such as art history) does not have a set goal or expected result, nor are there predetermined general procedures. The outcome of the…