The present thesis focuses on the pharmacological concept of drug-target interaction, which dates back to the beginning of modern pharmacology.

Researchers at LED3 are working together with biopharmaceutical company Galapagos to develop software for use in early drug discovery (funded by NWO). This software is able to design molecules with several simultaneously optimized characteristics and will also take prediction reliability into consideration…

Professor Jan Aart Scholte delivered an inaugural lecture, entitled “Governing a (Better) Global World” on Friday 4 February 2022 in the Groot Auditorium of the Academy Building, Rapenburg 73 in Leiden.

The post-PhD phase is discussed during the many formal and informal meetings PhD candidates have with their supervisors. However, there are also various online sources, workshops and events available to PhD candidates to better prepare for the next step.

On 8 February, the Leiden University Fund officially launched the LUF Children’s Fund. For one year, we will support research projects by Leiden scientists aimed at creating a better future for vulnerable children.

Anyone who creates a page for a magazine, a PowerPoint presentation, a brochure, a poster or dreams up an idea for an infographic is faced with important questions:

The Metabolic syndrome affects over 5 million people in the Netherlands. The HealthBox is an initiative from LUMC and NeLL to provide an innovative solution to help prevent and manage this chronic condition.

How can international investment law and arbitration take account of the public interest in, and more broadly, the public dimension of, the relations between foreign investors and host States ?

This thesis explored the molecular pharmacological mechanisms of targeting CB2R via investigation of novel drug discovery concepts such as target binding kinetics, allosteric modulation and biased signaling.

In 2025, we will celebrate 450 years of Leiden University—an occasion not just to look back, but to look ahead! The future belongs to our youth. However, young people’s mental and physical health is under significant pressure. That is why Leiden University places the highest priority on supporting young…

What is better for waste recycling: a plastic, paper or ceramic cup? A bio-based or fossil-based coating? Waste sorting at the source or at a recycling facility? Ask ten experts and you will get ten different opinions. We can all agree on one thing: doing nothing is not an option. Thus, Leiden University…

When to launch a next-generation product in a competitive market and how much capacity should be allocated to it

Research lines within the Pharmacy group:

Supervisor: Lizi Xia

How can mentors and social workers foster the vocational identity of at-risk youth and improve their prospects?

Promotor: Jelle S. Kaastra Co-promotor: Jelle de Plaa

Promotors: Prof.dr. T.H.W. Bäck, Prof.dr. B. Sendhoff (Technische Universität Darmstadt)

Whilst government’s ability to design ‘context-specific’ regional innovation policy is generally assumed to depend on the region’s decision-making power, the aim of this study is to investigate how regional government matters. In order to open up the black box of policy design, the study develops a…

Together with colleagues from the Stimson Center and in the framework of the Global Governance Innovation Network, Dr. Joris Larik has recently published the report

What are the functions of the endocannabinoid system?

The Brain and Education lab is a research group in the Institute of Education and Child Studies at Leiden University, the Netherlands. Our group is embedded in the Educational Sciences research program and the Leiden Institute of Brain and Cognition.

While ecosystems have concrete benefits for human society, these benefits are typically overlooked in decision-making.

Leiden University is an international, broad-based university. We distinguish five core domains for our research and teaching activities.

Despite the fact that gold nanoparticles (GNPs) are one of the most studied nanoparticles, there is still a necessity for new approaches allowing for effective protective coating to enable wider use of GNPs in biomedical applications.

In this project we study the properties of statistical- and rule-learning mechanisms in relation to the acquisition and evolution of language. We ask to what extent these mechanisms are unique to humans - or to human language - by comparing the acquisition of vocal structure in two species: humans (infants)…

HomininSpace is an agent based modelling and simulation system in which fluctuating carrying capacity is the key attractor for hominin dispersal. A parameterized and spatially explicit reconstructed palaeo-environment models available energy in the form of secondary biomass using reconstructed climate…

Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver

It has now been well established that shocks and turbulent motions in the intra-cluster medium (ICM) generated through cluster mergers can produce large-scale synchrotron emission.

Big data promises to transform public decision-making for the better by making it more responsive to actual needs and policy effects. However, much recent work on big data in public decision-making assumes a rational view of decision-making, which has been much criticized in the public administration…

Does student and teacher gender affect students’ performance and what is the role of gender stereotypes in this relation?

Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: Dr. L.H. Heitman

What kind of attentional focus can enhance learning and performance for musicians?

Catalysis is of extreme relevance in the production of everyday materials and plays a central role in many aspects of our life.

Promotor: J. Aarts

Promotor: A.P. IJzerman Co-promotor: L.H. Heitman

In this journal article, Dr. Joris Larik and Dr. Richard Ponzio put forward a broad-based pandemic recovery agenda that goes hand in hand with institutional reforms at the global level.

Towards Health and Resilience in Volatile Environments - People differ in how they are impacted by and respond to stressful experiences. Why is that?

Jelena Vićić and Richard Harknett offer an analytical construct to better understand the mechanism by which cyber-enabled influence operations work