The CIGR brings together a diverse range of unique expertise in genome research rooted in biology, chemistry and physics. Members of the CIGR investigate genome folding and genome transactions. An important aspect is direct as well as long term relevance for medicine.

The Joan van der Waals colloquium is an ongoing bi-weekly lecture series.

Promotor: Prof.dr. H.P. Spaink Co-promotor: Dr. B.E. Snaar

Leiden physicists have managed to detect a single molecule called dibenzoterrylene in a new crystal, and found that it is a candidate component for a quantum network. Future quantum computers will need such a network to work together while maintaining their advantages. Publication in ChemPhysChem jo…

In the current global context, there is a pressing need to address sustainable energy supplies to safeguard our Planet and its ecosystems. The choices made by human society have a significant impact on genetic evolution and climate.

In this thesis, the focus lies on studying glucocorticoid receptor dynamics in living cells with the aim of understanding how this transcription factor finds its DNA target sites to regulate transcription.

Viral hemorrhagic fever (VHF) is a group of acute diseases caused by highly infectious viruses including Ebola, Lassa, Dengue viruses. Its high mortality rate poses high risk to public health, however, studies on VHF have been hampered due to the non-availability of proper models and incomplete knowledge…

Microglia support the central and peripheral nervous system by forming the first line of defense against hazardous events. Microglia are increasingly acknowledged as critical players in neurodegenerative diseases, highlighting them as potential therapeutic targets.

Research projects for students of the University of Leiden and other Dutch Universities are often available at the MacBio group. The research lines are also described in the Research section. For details of specific projects contact the supervisor (Ubbink, Dame, Boyle, Jeuken or Wentink).

Apart from his activities as coordinator of the Academy of Creative and Performing Arts, Rogier Schneemann is co-founder, guitarist and composer of the Dutch-Italian group Azure Hiptronics, originally formed in 2006.

The Division of Systems Pharmacology and Pharmacy (SPP) aims to develop precision medicine approaches to characterize and predict variation in treatment response and enhance translational drug development strategies.

Chemists developed a new graphene-transferring method which makes use of cyclohexane. This new method leaves less impurities on graphene, is easier to handle than current methods and is widely applicable in graphene research. The publication will be on the cover of the journal ACS Central Science late…

Heterogeneous catalysis is one of the fundamental processes of modern life, being common in industrial refinery and hydrogen vehicles, all the way to the living cell. The dissociation of H2 on Cu(111) is an important benchmark system for studying heterogeneous catalysis, with a large and varied amount…

Mechanical forces are known to play an important role in bacterial colonies. In this dissertation, we study the self-organization at various stages of growing bacterial colonies, and focus on the mechanical effects of cell growth.

This project aims at describing the Khoisan languages !Ora (Korana/Griqua) and !Ui of South Africa.

This thesis is about the study of hydrocarbons via infrared spectroscopy.

We perform multidisciplinary research at molecular, cellular, and organismal levels of animal biology to increase fundamental understanding of health and disease.

Large areas of space are filled by molecular clouds that consist of gas and dust grains that are the remnants of dead stars. When these clouds start collapsing, the decreasing temperature and increasing density cause gas particles to start accreting onto dust grain surfaces.

Individual molecules are extremely hard to see through feeble fluorescence. Tiny gold nanorods serve as new antennas to intensify their signal 500 times. Publication on 24 February in Angewandte Chemie.

Single-celled organisms have stiffer DNA than multicellular lifeforms like humans and rice. Theoretical physicists managed to simulate the folding in full genomes for the first time to reach this conclusion. Publication in Biophysical Journal on February 7.

The long-held desire - to link structure directly to function and to explain molecular mechanisms based on basic chemical or physical principles - is finally coming closer, satisfying not only our scientific curiosity but also offering new solutions to the many challenges in the field of health, energy…

Please note that the course Molecular Biology for Physics will start on Monday 5 February. Please check the schedules for the time and location!

Ferritin is a spherical metalloprotein, capable of storing and releasing iron in a controllable way. It is composed of a protein shell of about 12 nm and within its cavity, iron is stored in a mineral form.

Promotores: G.W. Canters, T.J. Aartsma

In the past decade many population studies have been performed with the Atacama Large Millimeter/submillimeter Array (ALMA) to understand the bulk properties of protoplanetary disks around young stars. These population studies mostly consisted of low mass stars, with relatively few of the disks around…

The last blog of Leiden Law Blog of 2018 was written by Ladislav Kováč. He discusses the proposal for the Single-use Plastics Directive of the EU which was agreed upon on 19 December.

The "Van Marum Colloquia" are a collaborative lecture series between the LION and LIC institutes, focusing on fundamental and applied surface science.

Promotor: F.P. Israel, Co-Promoter: R. Meijerink

All research at Leiden University is organised into institutes. To do justice to the wide spectrum of research (and consequently teaching) that comes from these, you will find descriptions of all the Leiden institutes on these pages.

During my PhD research, I studied the photon statistics of light emitted by a microcavity that contains a single quantum dot (QD) on resonance.

Paleobotanist Menno Booi discovered that 250 previously described fossil tree species are objectively not distinguishable; they belong to only one single species.

The increasing resistance of pathogenic bacteria to antibiotics necessitates the discovery of new medicines.

Healthy aging is one of the prime goals in today's society and atherosclerosis is among the greatest causes of morbidity in elderly. Cardiovascular disease patients receiving treatment are often of advanced aged and have an aged immune system, which limits translating experimental findings to the pa…

Promotor: E.R. Eliel, Co-Promotor: M.J.A. de Dood

Research at the SBC group is comprised of the following research themes:

PhD at the Max Planck Institute of Molecular Plant Physiology, Golm – Germany

Emily den Boer of LAPP visited the Canal Cups Expo, displaying the plastic cups cleaned up by students after Leidens Ontzet.

This thesis advance our understanding and the application of molecular catalysts relevant to the reduction of oxygen as well as reduction of nitrite.

In this research group, headed by Bob Van de Water, cell signaling programs that underlie adverse drug reactions as well as cancer development and progression are unraveled. Adverse drug reactions involve cell injury in critical target organ cells which leads to the activation of cellular stress response…

Heterogeneous catalyzed processes are highly significant to the chemical industry. Dissociative chemisorption (DC) of molecules on surfaces is always considered as a step with a high degree of rate control for heterogeneous catalysis.

The ongoing increase in antimicrobial resistance combined with the low discovery of novel antibiotics is a serious threat to our health care.

Promotor: Prof.dr. E.F. van Dishoeck, Co-Promotor: M.R. Hogerheijde

Streptomyces are multicellular, Gram-positive bacteria in the phylum of actinobacteria which produce a high amount of bioactive natural products of which the expression is tightly coordinated with the life cycle.

The symposium is open to all registered participants and consists of a one-day programme and a poster session.