With the advent of multicore processors and data centers, computer hardware has become increasingly parallel, allowing one to run multiple pieces of software at the same time on different machines. Coordination of these pieces is best expressed in a coordination language as an explicit interaction protocol…

In a typical glycosylation reaction, a donor is activated to form a (variety of) electrophilic species which can react with a nucleophilic acceptor, following a reaction mechanism having both SN1 and SN2 character.

Scientific integrity is an essential element in the PhD trajectory and is addressed in several different settings.

Promotor: Prof.dr. S. Portegies Zwart

Find out how to apply for Visual Ethnography at Leiden University by following our step-by step guide.

Trust in public institutions in the Tata Steel case and beyond

Find out how to apply for Policy in Practice at Leiden University by following our step-by step guide.

Promotor: G.A. van der Marel, Co-promotor: D.C. Codée

Promotor: G.A. van der Marel, Co-promotor: J.D.C. Codée

From Los Angeles to Tokyo, Urban Sociolinguistics is a sociolinguistic study of twelve urban settings around the world.

Psychoeducational Assessment, Intervention and Rehabilitation (PAIR) publishes high quality articles on theoretical and empirical research regarding psychological and psychoeducational assessment, intervention, and rehabilitation in all areas related to cognitive and socio-emotional development.

The goal of this study is to systematically investigate how intonation (speech melody) is conveyed in whispered speech.

How were (post) colonial migrants included in post-war welfare systems?

On 18 May 2022, Annelien Bouland defended her thesis 'Please give me my divorce: an ethnography of Muslim women and the law in Senegal'. The doctoral research was supervised by Prof.dr. J.M. Otto, Prof.dr. M.M.A. Kaag and Dr.ir. C.I.M. Jacobs.

What are the foundations of the regulation of blasphemy, and in which manner, in legal as well as in extra-legal terms, has blasphemy developed over the last decades?

Nowadays, it is well known that hydrogen and helium (and small traces of lithium and beryllium) were created shortly after the Big Bang, while the heavier elements are created in the cores of stars at different evolutionary stages. When these stars explode as supernovae, they expel metals synthesised…

This thesis describes the design and synthesis of fragments of various cell wall carbohydrates of the Streptococcus species, including the branched Group B-specific antigen (GBC) of Group B Streptococcus, glycerol phosphate (GroP) modified group A carbohydrate (GAC), and the O-acetylated type 1 capsular…

The transition period in which men become fathers might provide an important window of opportunity for parenting interventions that may produce long-term positive effects on paternal care and, consequently, child development. Existing prenatal programs traditionally focus on maternal and infant health…

This work has described synthetic strategies towards well-defined structures resembling capsular polysaccharide (CPS) fragments, CPS mimics, teichoic acid (TA) fragments as well as a third-generation ring-closing tandem metathesis (RCM) linker to better exploit the potential of automated synthesis.

Promotor: F. Arbab

HomininSpace is an agent based modelling and simulation system in which fluctuating carrying capacity is the key attractor for hominin dispersal. A parameterized and spatially explicit reconstructed palaeo-environment models available energy in the form of secondary biomass using reconstructed climate…

One of the main challenges in the development of an effective anti-cancer vaccine is the generation of an adequate and directed cellular immune response.

This thesis describes the use of a combined approach of computational and experimental techniques to gain novel insights to understand the glycosylation reaction and its reactive intermediates.

Carbohydrates, or sugars, are the most diverse and most abundant biomolecules known. However, the isolation of carbohydrate samples in sufficient amounts and purity is often impractical or even impossible, so the chemical synthesis of glycosides becomes relevant. The glycosylation reaction, in which…

The project investigates how bilingual speakers navigate lexico-syntactic features, including grammatical gender, classifier systems, and the linear order of adjectives and nouns, across Spanish and Chinese in both unilingual and bilingual contexts.

Built Environment and Domestic Material Culture in the Medieval and Post-Medieval Cyclades, Greece (13th – 20th Centuries AD)

Has there been continuity or change in US counterterrorism policy since 9/11? What factors led to the continuity or change, and how do we classify any such continuity or change?

On the basis of the characteristic aspects of a picture, certain computers can tell us what the picture is showing. They can learn this in the same way that young children are able to learn to recognize images. Further improving these techniques opens the way to a whole range of new applications. Biology…

Schistosomiasis is an acute and chronic disease caused by blood dwelling parasitic trematodes of the genus Schistosoma, and it is classified as the second most socioeconomically devastating parasitic disease, second only to malaria.

Pseudomonas Aeruginosa is a Gram-negative bacterium which can form biofilms, increasing its resistance against antibiotics and the host immune system. Polysaccharides are an integral part of this biofilm, one of these polysaccharides is called Psl. PslG is a glycosidase, able to cleave this polysaccharide,…

This Thesis describes a strategy to synthesize 1,2-cis-oligosaccharides modulated by additives, such as dimethylformamide (DMF), triphenylphosphine oxide (Ph3P=O) and N-methyl(phenyl)formamide (MPF), using building blocks that carry solely benzyl type protecting groups and are therefore of uniform r…

This book presents a comprehensive description of the grammar of Logba, one of the fourteen Ghana-Togo Mountain (GTM) languages spoken by approximately 7,500 speakers on the South-Eastern frontier of the Ghana-Togo border. It is the outcome of fifteen months research in Logba speaking communities.

This research project problematizes the applicability of ballet within a contemporary choreographic practice.

Antibiotic resistance, caused by widespread use of antibiotics, leads to bacterial infections that are difficult, if not impossible, to treat and is a major worldwide health concern.

Promotor: Prof.dr. E. Deprettere

Promotor: Prof.dr. A. Achucarro

Leiden University is developing new short stay living space for foreign guests and employees. De Kloksteeg is currently the last of four projects that has been renovated by the Leiden University Real Estate directorate since 2017. The Service Centre International Staff (SCIS) is responsible for rental…

This thesis focuses on the X-ray spectral analysis of merging galaxy clusters and the plasma code development for future high-resolution X-ray spectroscopy observations.

Together@FGGA – Together towards a safe, inclusive and balanced work environment

Can conspiracy constructions explain for hatred of the system? And if so, should conspiracy constructions be considered to be a risk in terms of national security?

Promotores: Prof.dr. J. Kuiper, Prof.dr. P.H.A. Quax

In human cells, a meter-long DNA is condensed inside a micrometer-sized cell nucleus. Simultaneously, the genetic code must remain accessible for its replication and transcription to functional proteins.

Eduard Fosch-Villaronga and Hadassah Drukarch from eLaw - Center for Law and Digital Technologies, recently published the book ‘AI for Healthcare Robotics’, published by CRC Press from Taylor and Francis Group in their AI for Everything Series.

Over the last three decades, the discovery of exoplanets has revealed the boundless variety of worlds beyond our own Solar System⁠. Majority of planetary systems contain short-period planets that are larger than Earth but smaller than Neptune⁠.

Promotor: R. Cramer

Bikes are one of the most sustainable ways of travel which use should be promoted by the University.

Find out how to apply for Global Ethnography at Leiden University by following our step-by step guide.

The library of the Papyrological Institute is the most complete facility for papyrological studies in the Netherlands.

This book is a much-needed update on our understanding of public diplomacy. It intends to stimulate new thinking on what is one of the most remarkable recent developments in diplomatic practice that has challenged practitioners as much as scholars.