Research at the SBC group is comprised of the following research themes:

In this research group, headed by Bob Van de Water, cell signaling programs that underlie adverse drug reactions as well as cancer development and progression are unraveled. Adverse drug reactions involve cell injury in critical target organ cells which leads to the activation of cellular stress response…

Emily den Boer of LAPP visited the Canal Cups Expo, displaying the plastic cups cleaned up by students after Leidens Ontzet.

Heterogeneous catalyzed processes are highly significant to the chemical industry. Dissociative chemisorption (DC) of molecules on surfaces is always considered as a step with a high degree of rate control for heterogeneous catalysis.

Streptomyces are multicellular, Gram-positive bacteria in the phylum of actinobacteria which produce a high amount of bioactive natural products of which the expression is tightly coordinated with the life cycle.

The ongoing increase in antimicrobial resistance combined with the low discovery of novel antibiotics is a serious threat to our health care.

The symposium is open to all registered participants and consists of a one-day programme and a poster session.

Promotor: Prof.dr. E.F. van Dishoeck, Co-Promotor: M.R. Hogerheijde

Which brain cell does what, when Parkinson's disease arises? It won't be long before this jigsaw is solved piece by piece. Ahmed Mahfouz, computational biologist, combines bio-knowledge from Leiden with algorithms from Delft and is getting closer to finding the key.

This thesis describes a study from both a theoreticaL and an experimental point of view.

Despite the history of studies on methanol formation from CO2, the dominant elementary reaction steps that constitute the chemical mechanism for this catalyzed process are not determined.

Promotor: H.V.J. Linnartz

Hybrid zones occur where two species meet and produce offspring (hybrids). Typically, hybrids show a considerable reduction in fitness. In this thesis two hybrid zones are treated.

The Royal Netherlands Academy of Arts and Sciences (KNAW) selects prominent researchers as members based on their scientific achievements. On September 17th, the KNAW will install 21 new members, including Leiden physicist Michel Orrit and chemist Hermen Overkleeft.

Leiden researchers have found minute movements in the laccase enzyme. This discovery could lead to the development of much more efficient biofuel cells. Publication in Biophysical Journal.

The "Van Marum Colloquia" are a collaborative lecture series between the LION and LIC institutes, focusing on fundamental and applied surface science.

Astronomers who simulate galaxies do not always get the same result, even when they start from identical conditions. New research from Leiden University shows that this is not a flaw, but a consequence of how galaxies behave — and how they are modelled.

How do plant defense genes get activated?

The formation and evolution of galaxies is fundamentally driven by the formation of new stars out of cold gas.

Promotor: E. Bouwman, Co-Promotor: S. Bonnet

The quantum nature of matter and light has grown into a broad and fruitful research field for theorists and experimentalists alike. It combines foundational research with toward applications, the most well known of which is the quantum computer.

The Netherlands X-omics Initiative is a new facility as part of the National Roadmap for Large-Scale Research Infrastructures. It is partly funded by NWO with a total budget of 40 million euro. The project started on September 2018 and will last for ten years.

With the powerful electron microscopes at NeCEN we study abnormalities in cells of blood vessels in cardiovascular disease, the interaction between pathogens and hosts in infectious diseases, molecular processes that cause cancer and the interaction between drugs and target proteins. Drug development…

Developing new medicines is one of modern science's most significant hurdles, a process marked by high costs, long timelines, and frequent failures of promising candidates.

Research at the Macromolecular Biochemistry group is comprised of the following research themes:

Promotor: Prof.dr. E. F. van Dishoeck, Co-promotor: A. N. Heays

The aim of the research presented in this thesis was to develop new methods forchallenging systems in liquid-state NMR using paramagnetic effects generated by thetwo-armed probe CLaNP-5.

Promotor: T. Schmidt, Co-Promotor: B.E. Snaar-Jagalska

Heterogeneous catalysis is essential to many industrial applications. These catalysts are often comprised of supported nanoparticles, which contain various different surface sites.

Several techniques are explored for going beyond the born-oppenheimer static surface model for molecule-surface reactions.

The work in this thesis demonstrates how to obtain an atomic-scale picture of a diverse set of complex surface structures observed using STM, under disparate conditions.

Promotor: Prof.dr. T. Schmidt, Co-Promotor: Dr. ir. S.J.T. van Noort

To be eligible for Chemistry at Leiden University, you must meet the following admission requirements.

In surface science there is great effort to move from studying simple, flat model surfaces in vacuum to investigating more complex model catalysts in gas environments (in situ). This thesis gives three examples of such studies using microscopy and spectroscopy.

What is the difference between highly visible and poorly visible monuments on the alignment? And is this difference reflected in the social position of the dead buried underneath these mounds.

Scientists at Leiden University (Netherlands), Stuttgart University (Germany) and Ural Federal University (Russia) have successfully put forward a novel, computed, reaction mechanism that was experimentally tested and show that formaldehyde is formed at much earlier stages in the birthplaces of stars…

Biophysicist Alireza Mashaghi and his collaborators are taking up the fight against muscular dystrophy: genetic disorders that cause muscle weakness. They want to inhibit the clumping of proteins that results in toxic aggregates. For this, the team receives 550,000 euros from Health Holland. The team…

Research groups in the Quantum Matter & Optics programme investigate electronic properties of matter and light-matter interactions with emphasis on quantum information.

Michel Orrit has received an NWO-TTW Open Technology Programme grant. He will use it to image single molecules without the need for fluorescence.

This dissertation combines the use of defined microenvironments, high-resolution fluorescence microscopy, and time-resolved analysis, to study intracellular and cellular motility.

This thesis presents pioneering work on the panchromatic emission of some of the most luminous galaxies in the early Universe: star forming galaxies and active galactic nuclei.

Animal diet studies are critical for understanding ecological processes such as trophic interactions, energy flow, and nutrient cycling. By examining what animals consume, ecologists gain insights into species specialization, predator-prey relationships, and ecosystem management.

In the search for sustainable energy solutions, the idea of artificial photosynthesis has been proposed as an approach with which to use water and sunlight to produce hydrogen.

Promotor: E. Bouwman, Co-promotor: S. Bonnet

This thesis takes steps toward understanding the interaction between gas-phase and solid-state molecules in star- and planet-forming regions.