What are the social and neural mechanisms that contribute to fluctuations in self-esteem in healthy adolescents and adolescents with depression?

Serious forms of anxiety concerning other people’s opinions can hinder teenagers at school in social interactions or carrying out tasks. Psychologist Anne Miers is looking for ways to reduce this so-called ‘social anxiety’.

Heightened activation of the striatum that adolescents show in response to reward is often associated with risk-taking and negative health consequences. This article in Nature Communications investigates a potential positive side of this heightened activation. It shows that the activity peak in late…

What is the neural basis of social decision-making across childhood, adolescence and adulthood and what are the developmental patterns in terms of behavior and brain activation?

To investigate the effectiveness of an online self-help programme for people with HIV and depressive symptoms.

A study on the development of prosocial behaviour.

Our mission is to improve the description, prediction, understanding and the prevention and treatment of mood disorders, including unipolar and bipolar depression, as well as suicidal thoughts, feelings, and behaviors. To tackle this ambitious mission, we focus on several research streams.

Optimization, mechanisms of action and predictors of the outcome of light therapy in depression: A multicenter randomized trial

Trust and reciprocity are two important social behaviors that help adolescents to navigate their social world successfully. In their empirical article in Journal of Research on Adolescence, van de Groep, Meuwese, Zanolie, Güroğlu, and Crone describe the development of trust and reciprocity in adolescents…

Is blended care a feasible and effective treatment method for social anxiety in adolescence?

We found that, next to the effectiveness of the intervention, it’s also very likely that the intervention is cost-effective compared to attention only.

Promotores: C.A.J. Knibbe; J.N. van den Anker, Co-promotores: H.P.A. van Dongen; B. van Ramshorst

What is the effectiveness of (booklet or online) self-help programmes for people with somatic stressors and depressive symptoms? What works best for whom? How to improve motivation and adherence?

Up to 50% of all children and adolescents growing up worldwide are exposed to at least one form of childhood adversity (CA), which is one of the strongest predictors for later-life psychopathology.

In a longitudinal study, Eichengreen and colleagues explored how the certain aspects of emotional intelligence impact the development of adolescents’ mental health, thus identifying potential warning signs and targets for intervention programs. Despite a higher risk for mental health issues and lesser…

It may seem as though adolescents do as they please, but they are more sensitive to their parents’ opinions than they would appear. The adolescent brain reacts strongly to parental criticism or praise. These are the results of a study by an interdisciplinary research group of psychologists and neuroscientists…

Disclaimer: Manuscripts related to the Resilience Center are for academic purposes only and are not intended for mass distribution or copying. Please refer to applicable laws for fair use, including copyright holders' restrictions on publications.

Can positive peer feedback break the cycle of negative self-relevant cognitive processes and reduce self-reported anxiety in early adolescents?

Imagine getting a notification on your mobile phone with your personal code for impending mental health problems or even depression: yellow, orange, or red. Science fiction? Not for scientist Eiko Fried. 'There is a real chance we can prevent some mental health problems before they occur.' Want to participate…

What are the circadian disturbances underlying depression vulnerability? How are they related to mood, cognition and sleep ?

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CERQ is a questionnaire measuring cognitive coping strategies developed by Dr. Nadia Garnefski and Dr. Vivian Kraaij.

During adolescence, mood disorder onset peaks. Mood variability is associated with negative mental health outcomes, so understanding biological factors that might be associated with mood variability, such as sleep and structural brain development, could elucidate the mechanisms underlying mood and anxiety…

Nowadays children grow up with social media. This may influence the development of brain regions involved in social interaction. In their review article in Nature Communications, Crone and Konijn illustrate how neuroscience can contribute to a better understanding of how media and peers influence adolescents'…

The Leiden Index of Depression Sensitivity (LEIDS) measures cognitive reactivity (CR) to sadness, an aspect of cognitive vulnerability to depression, conceptually similar to rumination.

Persistent somatic symptoms are long term symptoms that lack a clear medical explanation. These symptoms have a high prevalence where most people know someone who experiences such symptoms or they experience such symptoms themselves. Symptoms can vary greatly in and between people. While one person…

Bernet Elzinga (Clinical Psychology) is one of the seven scientists from the Leiden University who has received a Vici grant of 1.5 million euros from NWO. Vici is one of the largest grants for individual scientists in the Netherlands. The funding will enable her to do research for the next five years…

Fundamental insights into the working of the adolescent brain help lecturers and parents to teach adolescents to function better. Professor Eveline Crone studies executive functions – such as planning and behaviour – in the adolescent brain.

Effects of age and social anxiety

Are you thinking about studying Child and Adolescent Psychology? Learn more and watch the videos.

Why do children with an Autism Spectrum Disorder (ASD) have difficulties with acquiring emotion regulation skills; and how is this related to their social impairments and comorbid psychopathology?

PhD defence

Adolescents with good friendships experience fewer anxiety and depression symptoms, PhD student Iris Koele discovered in her research on high school students' social relationships. 'As a psychologist, I include friends in the treatment plan: who do you call when things are not going well?'

How does having limited access to the social world affect Deaf or Hard of Hearing (DHH) children’s emotional development? And in turn, how do impairments in emotional functioning affect social development and the development of psychopathology?

This project investigates which aspects of social media content adolescents attend to and how these relate to their credibility judgments, aiming to systematically understand their susceptibility to misinformation and inform effective educational programs that foster youth’s resilience to misinforma…

In the specialisation Child and Adolescent Psychology , part of the Master in Psychology, you develop practical skills in assessing and managing developmental psychopathology.

What role do parent-child interactions play in the development, maintenance and treatment of depression in young people?

In online games conflicts between players may arise. Novin, Bos, Stevenson and Rieffe investigated factors that may explain why some adolescents react more angrily than others in this type of situation. In their realistically designed gaming environment, the (pre-programmed) fellow player suddenly started…

Pharmacometrist Bas Goulooze has won the prestigious Lewis Sheiner Student Session award. He received the prize of 300 euros at the annual conference of the Population Approach Group Europe (PAGE) in Stockholm, where he presented his research for 800 people.

A new therapy for the serious Graft-versus-Host disease

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Teens with depression appear to be more sensitive to criticism from their parents than their healthy peers are.

How do genetic and environmental factors make us vulnerable to depression?

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Study information

Children and adolescents really do use their ‘smart’ brain areas. This has been confirmed by an extensive and long-running study of the brain carried out by developmental psychologist Sabine Peters . Her findings can have important consequences for education. PhD defence 27 January.

Depression has traditionally been linked to increased inflammation. Innovative research by psychologist Eiko Fried refutes this popular assumption. He shows that specific depression symptoms such as sleeping problems explain this relationship. Publication in Psychological Medicine .

My ERC Starting Grant, funded with €1.5 million for 5 years as part of the Horizon 2020 research and innovation program, is focused on building the early warning system WARN-D to reliably forecast depression in young adults before it occurs. Why depression, and why prediction?

People already diagnosed with a mental disorder before the COVID-19 pandemic did not show a disproportionate increase in symptoms afterwards. This is one result from the first systematic review of longitudinal studies following their study population from before to during the first eighteen months of…

Somatic symptoms, such as pain, itch, and fatigue have been shown to have a bidirectional relationship with mental symptoms. Although acute somatic symptoms serve some adaptive properties, chronic symptoms can instead lead to interference in daily activities and lower quality of life.