1,033 search results for “biological clock” in the Public website
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Synthesis of well-defined ADP-Ribosylated biomolecules
Promotor: G. A. van der Marel, Co-promotor: D. V. Filippov
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Mechanistic modelling of drug target binding kinetics as determinant of the time course of drug action in vivo
Drug-target binding kinetics determine the time course of the central event in pharmacotherapy: Drug-target interaction.
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Early Medieval English Life Courses: Cultural-Historical Perspectives
How did the life course, with all its biological, social and cultural aspects, influence the lives, writings, and art of the inhabitants of early medieval England?
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Patterns in natural systems
Promotor: A. Doelman, Co-promotores: P.J.A. van Heijster; A. Zagaris
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Narrative Science: Reasoning, Representing and Knowing since 1800
Narrative Science examines the use of narrative in scientific research over the last two centuries.
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Contracts and supplies
Find out about the effects of Brexit on contracts and supplies.
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Spin-label EPR Approaches to Protein Interactions
Promotor: Prof.dr. E.J.J. Groenen
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Louise Jawerth Lab
Research in the Jawerth lab focuses on using principles from soft condensed matter physics to understand important biological materials.
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Self-assembly of Colloidal Particles
The miniaturization of machines towards the micron and nanoscale requires the development of joint-like elements that enable and constrain motion. We developed a facile method to create colloidal joints, that is, anisotropic colloidal particles functionalized with surface mobile DNA linkers that control…
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Health, Ageing and Society
Are you interested in an interactive Master’s programme that prepares you for important roles in the innovations of our future healthcare? The Health, Ageing and Society Master’s focuses on biological, individual and social aspects of healthy ageing, as well as emphasizing on personal and professional…
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Iminosugars as glucosylceramide processing enzymes inhibitors: design, synthesis and evaluation
This Thesis describes the design, synthesis and evaluation as glycoprocessing enzyme inhibitors of focused libraries of iminosugars.
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Health, Ageing and Society
Are you interested in an interactive Master’s programme that prepares you for important roles in the innovations of our future healthcare? The Health, Ageing and Society Master’s focuses on biological, individual and social aspects of healthy ageing, as well as emphasizing on personal and professional…
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New professor Luca Giomi creates his own physics of living systems
Swarms of drones, pedestrians or the cells in your body. Those are all examples of active matter: materials whose building blocks can move autonomously. That’s what Luca Giomi studies. Giomi has been appointed Professor of theoretical physics in the area of soft matter and biological physics at the…
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Symposium 2023: Reaction mechanisms in heterogeneous, inorganic and biological electro(photo)catalysis
Conference
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Biological evaluations of nanocarriers to improve the effectiveness of colorectal cancer treatment
PhD defence
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Self-folding metamaterial
The more complex the object, the harder it is to fold up. Space satellites often need many small motors to fold up an instrument, and people have difficulty simply folding up a roadmap. Physicists from Leiden and Amsterdam have now designed a structure that folds itself up in several steps. Publication…
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Elastic Leidenfrost Effect enables soft engines
Water droplets float in a hot pan because of the so-called Leidenfrost effect. Now physicists have discovered a variation: the Elastic Leidenfrost effect. It explains why hydrogel balls jump around on a hot plate making high pitched sounds. Publication in Nature Physics on July 24.
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Postdoc Computational Modeling for Drug Safety Prediction
Science, Leiden Academic Centre for Drug Research (LACDR)
- Spanish 2
- Week 5: 5-11 February 2017
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Islam and law
Systematic investigations into religious precepts, worldly rules of law and legal practices in the Muslim world show clearly how these societies deal with justice and injustice. Sharia, the Islamic ‘legal system’, plays an important role in this context.
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Animal sciences and health
In the research theme ‘Animal Sciences and Health’, we work with various animal species to gain insights into fundamental biological processes in both animals and humans.
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Research
The current projects of the Molecular Physiology group focus on proteins of the endocannabinoid system, kinases and antibacterial targets. MSc- and BSc-students can contact Jessica van Krimpen-Kraaijenoord to apply for research internships.
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Research
Research at the Macromolecular Biochemistry group is comprised of the following research themes:
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Solid State NMR and modelling of photoinduced energy and electron transfer
Huub de Groot is professor in Biophysical Organic Chemistry. With his team he works in the field of photosynthesis and artificial photosynthesis. The molecular basis for photosynthesis is formed by protein complexes and organelles that contain chlorophyll molecules. The antenna systems herein capture…
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Image-based Computational Biology
In this research group, led by Dr. Joost Beltman, the aim is to employ mathematical and computational dynamical modelling approaches in order to quantitatively and mechanistically understand the dynamical behaviour and regulation of intracellular networks of genes, proteins and metabolites as well as…
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Scouring the brain for causes of psychiatric illnesses
What happens in the brains of people with psychiatric illnesses? With a €23.23 million gravity grant, scientists from different fields will search for biological causes over the next decade. ‘By joining forces, we hope to improve diagnosis and treatment for patients with these diseases.’
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Record sum Leiden Science Run for refugee scholars
The Leiden Science Run 2019 has raised a record sum of 12,135 euros for refugee student foundation UAF. No less than 101 teams – also a record – and the sponsors CORPUS and Janssen Biologics raised the amount.
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Supramolecular materials: from biosensors to cell delivery devices
The group of Dr. Roxanne Kieltyka designs and synthesizes molecules that self-assemble into polymeric materials using specific non-covalent interactions. These substrates can be used for numerous applications in medicine ranging from disease detection to cell delivery depending on the (bio)molecular…
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Colloidal LEGO with peptides
Kros
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Research
An overview of the research at the Biologics Formulation group
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Oncode Accelerator
Providing each cancer patient with the right treatment remains a challenge. Oncode Accelerator aims to change this by innovating the way we develop cancer treatments, thus ensuring the patient is at the heart of the process. Leiden University, the LUMC and other partners will implement this new way…
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Research
The researchers at the Institute of Education and Child Studies focus on child rearing and the development of children and adolescents with and without developmental and other problems, in biological and non-biological families, childcare, education and care institutions.
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Diego Garlaschelli Group - Econophysics and Network Theory
We study the structure, dynamics and physics of complex networks emerging from the intricate interconnectedness of the constituents of large systems.
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Combination, variation and reproductive cues in vocalisations of the common marmoset (Callithrix jacchus)
How do common marmosets combine their calls into sequences and how are their vocalisations influenced by reproductive state?
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Measuring water life
Human activity, such as pollution, may disturb the balance of living water systems, which has consequences for biodiversity, but also for other functions such as water purification. Leiden University maps living water systems using the most advanced technologies.
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Education and Child Studies
How do people develop and how do they learn? How does their environment affect them? How do we ensure that they develop in optimal fashion? And what can we do if problems occur? These are questions that the researchers at the Institute of Education and Child Studies try to answer.
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Research
Physicists at the Leiden Institute of Physics (LION) conduct fundamental research into physical phenomena. They are inspired by curiosity and the desire to know more about the world in which we live. This research has always paved the way for new practical applications. These are something that the…
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PhD Theses
A full overview of MCBIM PhD theses.
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Computational modeling of tumor growth and metastasis and the role of the immune system in tumor destruction
In this project, we aim to obtain a quantitative understanding of the role of the immune system in tumor regression, of the role of tumor cell heterogeneity in cancer growth and of tumor cell migration properties.
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Education
Education & outreach
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Career prospects
The knowledge and skills you will acquire will qualify you for many different jobs. Possible careers include: researcher of learning, behavioural and emotional problems in children, or designer of prevention and intervention programmes.
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Above- and belowground interactions in Jacobaea vulgaris: zooming in and zooming out from a plant-soil feedback perspective
PhD defence
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Bacterial Chromatin
The relative simplicity of the bacterial cell, short generation times and well defined and inexpensive culturing conditions have significantly contributed to our understanding of many complex biological systems. Yet the workings of the bacterial genome, seemingly impossibly compressed within a tiny…
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RAISE Study
The aim of the RAISE study is to investigate how resilient people respond to stress. Specifically, we will study how key biological systems (HPA-axis, immune system) interact with the brain and social environment in order to facilitate resilient functioning after childhood adversities.
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Anisotropy, multivalency and flexibility-induced effects in colloidal systems
We have studied the impact of particle shape anisotropy, multivalent interactions and flexibility on systems of micron-sized colloidal particles.
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Aria of the Dutch North Sea
Promotores: C. J. ten Cate; M. A. Ainslie. Co-promotor: W. Slabbekoorn
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Systems pharmacology of the endocannabinoid system
What are the functions of the endocannabinoid system?
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Teacher knowledge and lesson design
The studies reported in this thesis were situated in the context of an innovation of Dutch secondary school biology curricula. As in any innovation, the practical knowledge of teachers determine the outcomes through the decisions they make while planning and teaching their lessons. The aim of the studies…
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Dormancy in stochastic interacting systems
Organisms often need to adapt more efficiently and devise new strategies for surviving difficult ecological circumstances.