2,683 search results for “cancer research” in the Public website
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Research
Research at the MCBIM group is comprised of the following research themes:
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Hanneke Leegwater
Science
h.leegwater@lacdr.leidenuniv.nl | +31 71 527 6274
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Maaike Wensveen
Faculteit Rechtsgeleerdheid
m.wensveen@law.leidenuniv.nl | +31 71 527 8541
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Lude Rozema
Faculteit der Sociale Wetenschappen
l.j.rozema@fsw.leidenuniv.nl | +31 71 527 2727
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Frans de Ruiter
Faculty of Humanities
f.c.de.ruiter@umail.leidenuniv.nl | +31 71 527 1480
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Marcel Cobussen
Faculty of Humanities
ma.cobussen@hum.leidenuniv.nl | +31 71 527 5041
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Research
An overview of the research at the Cancer Dug Target Discovery group.
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Hannah Bliersbach
Faculteit Rechtsgeleerdheid
h.bliersbach@fgga.leidenuniv.nl | +31 70 800 9500
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Cancer patients want a doctor who shows empathy and doesn’t make vague promises
Patients with incurable cancer want their oncologist to be clear but to show empathy too. They find hard and vague communication harmful. These are the results of a study by psychologists from Leiden that has been published in the American journal Cancer.
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NWO awards funding for LACDR research project to develop novel engineering approaches to study cancer immunity
As part of the HTSM2017 funding program, the LACDR division for Systems Biomedicine and Pharmacology received 1.08 million euros for a research project to develop novel engineering approaches to fight cancer.
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Arjen de Vetten
ICLON
a.j.de.vetten@iclon.leidenuniv.nl | +31 71 527 1771
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Ewa Snaar-Jagalska
Science
b.e.snaar-jagalska@biology.leidenuniv.nl | +31 71 527 4980
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Research
An overview of the research at the Biologics Formulation group
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Modelling metastatic melanoma in zebrafish
Death in all types of melanomas is generally caused by metastasis. Uveal melanoma (UM) is the most common intraocular melanoma, there are currently no (patient-derived) animal models that faithfully recapitulate metastatic dissemination of UM.
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Zebrafish: a new engraft model to study Ewing sarcoma progression
Can zebrafish provide a fast, sensitive in vivo vertebrate model for identifying novel mechanisms of Ewing sarcoma progression and for development of new anticancer compounds in a time- and cost-effective manner?
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Cancer cell mechanism found to be used against itself
Leiden biophysicists have found a new possible way to attack cancer cells. They have located ‘sinkholes’ on the cells where receptor proteins disappear from the surface. If a drug could push these proteins towards those areas, it would kill the cancer cell.
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Jennifer Doekhie
Faculteit Rechtsgeleerdheid
j.v.o.r.doekhie@law.leidenuniv.nl | +31 71 527 5301
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Research
The research conducted at the Leiden Academic Centre for Drug Research is clustered within the divisions of BioTherapeutics, Drug Discovery & Safety and Systems Biomedicine and Pharmacology, and the Metabolomics and Analytics Centre.
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New insight into immune cell behaviour offers opportunities for cancer treatment
An international group of scientists has discovered that certain cells of our immune system – the so-called T cells – communicate with each other and work together as a team. To fight an infection they stimulate each other’s growth, but at the same time, they inhibit each other when there is a surplus…
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Important developments in lung cancer surgery
Professor of Cardiothoracic Surgery, in particular pulmonary surgery, Jerry Braun will give his inaugural lecture on Friday 23 September entitled ‘Out of countless millions’. Braun has been a professor and acting head of the LUMC’s Department of Cardiothoracic Surgery since January 2020. Covid meant…
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Screening enormous databases to find a cure for cancer
Pharmaceutical research should make more use of data science, says Gerard van Westen, postdoctoral fellow at the Leiden Academic Centre for Drug Research (LACDR). ‘If we want to have better drugs, we should start with data.’
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Harold Nefs
Faculteit der Sociale Wetenschappen
h.t.nefs@fsw.leidenuniv.nl | +31 71 527 3992
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Ralph Rippe
Faculteit der Sociale Wetenschappen
rrippe@fsw.leidenuniv.nl | +31 71 527 3889
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Ben Smit
ICLON
smit@iclon.leidenuniv.nl | +31 71 527 3498
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Terry Mostert
Faculteit der Sociale Wetenschappen
t.m.m.mostert@fsw.leidenuniv.nl | +31 71 527 2727
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Nina Krupljanin
Faculteit der Sociale Wetenschappen
n.krupljanin@fsw.leidenuniv.nl | +31 71 527 2727
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Sarah Plukaard
Faculteit der Sociale Wetenschappen
s.c.plukaard@fsw.leidenuniv.nl | +31 71 527 7937
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Tamara Platteel
ICLON
tplatteel@iclon.leidenuniv.nl | +31 71 527 6498
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€10.6 million for innovative toolboxes to tackle brain cancer
Researchers at the Universities of Amsterdam (Uva) and Leiden together with the Netherlands Cancer Institute and Oncode Institute have received a €10,6 million ERC Synergy Grant to develop innovative therapeutic approaches to target glioblastoma. This is a deadly primary brain tumour for which no curing…
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New cellular imaging paves way for cancer treatment
A new technique using fluorescent imaging to track the actions of enzymes might aid drug design for new anti-cancer, inflammation and kidney disease treatments. Researchers at the University of York and Leiden University have published these findings in Nature Chemical Biology.
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Fighting cancer with light (and a drug that self-assembles into nanoparticles)
Chemotherapy that does not harm the body, but effectively fights cancer cells: that is the goal of chemist Sylvestre Bonnet and his team. During his PhD research, chemist Xuequan Zhou brought that goal a little closer. He developed molecules that, upon injection in the bloodstream, self-assemble into…
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Bioorthogonal Antigens as Tool for Investigation of Antigen Processing and Presentation
In order to be able to develop effective medicine and treatments to prevent or cure autoimmune diseases or cancer we need to understand the mechanisms how they arise and what drives their course.Unravelling the fundamental molecular mechanisms influencing the onset and course of diseases such as allergies,…
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Research
The current projects of the Molecular Physiology group focus on proteins of the endocannabinoid system, kinases and antibacterial targets. MSc- and BSc-students can contact Jessica van Krimpen-Kraaijenoord to apply for research internships.
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The chemistry behind cancer drugs: searching for fewer side effects
PhD candidate Dennis Wander searches for the best of both worlds. That is to say: a cancer drug that is effective and also has minimal side effects. To this end, he makes new molecules inspired by two existing medicines. And not without result: ‘We have created a new variant that is very promising.’…
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Sylvestre Bonnet
Science
bonnet@chem.leidenuniv.nl | +31 71 527 4260
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Monitoring Cytoskeletal Conductance Variation for Sensing Cancer Drug Resistance
Actin and microtubules form cellular cytoskeletal network, which mediates cell shape, motility and proliferation and are key targets for cancer therapy. Changes in cytoskeletal organization correlate with proliferative capacity and invasiveness of cancer cells. These changes expectedly lead to altered…
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Key publications
Key publications of the Cancer Drug Target Discovery group
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Breast cancer patients remember more information if doctors show empathy
Patients with incurable breast cancer remember more information about their treatment if their doctor is more empathetic during consultations. These are the results of research by psychologists from Leiden University in collaboration with Nivel research institute. Publication in Patient Education and…
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Cell Systems and Drug Safety
The research within the Division of Cell Systems and Drug Safety, headed by Prof. Bob van de Water, is focused on novel therapeutic modalities and novel concepts in early drug discovery, in order to develop more effective and safer therapeutic strategies. We generate advanced cell and computational…
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Special nanoparticles for cancer therapy! Will you help?
Developing a better treatment for patients with head and neck cancer, that is what Binanox, The 2022 iGEM Leiden team, want to achieve. They hope to raise at least 10,000 euros for this cause. Support their crowdfunding campaign today.
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Unlocking the potential of small molecules in cancer therapy
How can we translate more fundamental discoveries into clinical solutions for patients? From that question, the Oncode Accelerator programme emerged. Professor of Molecular Physiology Mario van der Stelt has been one of the driving forces behind it since its inception. In an interview on the website…
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AI application in pathology reveals novel insights in endometrial cancer diagnostics
Research at the Leiden University Medical Center (LUMC) Department of Pathology shows the power of artificial intelligence (AI) applied to endometrial carcinoma microscopy images. The group of Dr. Tjalling Bosse offers novel insights that could improve diagnosis and treatment of uterine cancer. Their…
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Stem cells as cure
Leiden has a long history in the treatment of blood cell cancer. Research to find better therapies never stands still. One of the potential treatments currently being worked on is a ‘living medicine’.
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Role of leukocytes in metastasis formation in a zebrafish
How do macrophages and neutrophils contribute to metastatic onset?
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Research
Research at the BIOSYN group is comprised of the following research themes:
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Drug research
In the Drug Research theme, we primarily work with rodents. Rodents, such as mice, are one of the most common laboratory animals. These small mammals are easily housed and exhibit a rapid rate of reproduction.
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‘Using real-world data to enhance our healthcare system’
On 16 May 2022, Professor Michel Wouters from the Department of Biomedical Data Sciences at the Leiden University Medical Centre (LUMC), will deliver his inaugural lecture titled ‘Quality of Cancer Care: why the real world matters’. Wouters will use the opportunity to describe how quality registries…
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References to the Steel Industry in a Definitive GGD Report on Lung Cancer in the Dutch IJmond Region
Arco Timmermans is Professor by special appointment Public Affairs at the Institute of Public Administration. On Dutch television programme 'EenVandaag', he discussed the remarkable changes that have been made in a report on lung cancer in and around the Dutch city of Beverwijk that was presented by…
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‘How can we translate the language of cells into cancer therapies?’
On 23 April 2021, Professor Alfred Vertegaal from the Department of Cell and Chemical Biology at the Leiden University Medical Center (LUMC) delivered his inaugural lecture ‘Unraveling and exploiting cellular communication codes’. Vertegaal used the opportunity to describe how research in the field…
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impact does communication have on individuals dealing with advanced cancer? Looking for participants
This study is important because it seeks to uncover whether clinicians' communication influences neurobiological and physiological outcomes for patients.